BR112017000529A2 - comprimido dispersível de misoprostol - Google Patents
comprimido dispersível de misoprostolInfo
- Publication number
- BR112017000529A2 BR112017000529A2 BR112017000529A BR112017000529A BR112017000529A2 BR 112017000529 A2 BR112017000529 A2 BR 112017000529A2 BR 112017000529 A BR112017000529 A BR 112017000529A BR 112017000529 A BR112017000529 A BR 112017000529A BR 112017000529 A2 BR112017000529 A2 BR 112017000529A2
- Authority
- BR
- Brazil
- Prior art keywords
- misoprostol
- dispersible tablet
- pharmaceutically acceptable
- acceptable salt
- relates
- Prior art date
Links
- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 title abstract 3
- 229960005249 misoprostol Drugs 0.000 title abstract 3
- 239000007919 dispersible tablet Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010036246 Post abortion haemorrhage Diseases 0.000 abstract 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000005070 ripening Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
a presente invenção refere-se a uma formulação farmacêutica sólida que compreende misoprostol ou um sal farmaceuticamente aceitável do mesmo. em particular, a invenção se refere a um comprimido dispersível que compreende misoprostol ou um sal farmaceuticamente aceitável do mesmo, fornecendo rotas de administração alternativas. o comprimido é particularmente adequado para amadurecimento cervical, indução de trabalho de parto, prevenção e/ou tratamento de hemorragia pós-parto ou pós-aborto.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14/329,023 US20160008310A1 (en) | 2014-07-11 | 2014-07-11 | Misoprostol dispersible tablet |
EP14176821.8A EP2965750B1 (en) | 2014-07-11 | 2014-07-11 | Misoprostol dispersible tablet |
PCT/DK2015/050216 WO2016004960A2 (en) | 2014-07-11 | 2015-07-10 | Misoprostol dispersible tablet |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017000529A2 true BR112017000529A2 (pt) | 2017-11-14 |
Family
ID=53879283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017000529A BR112017000529A2 (pt) | 2014-07-11 | 2015-07-10 | comprimido dispersível de misoprostol |
Country Status (12)
Country | Link |
---|---|
US (2) | US11406615B2 (pt) |
EP (1) | EP3166597A2 (pt) |
JP (2) | JP6532529B2 (pt) |
AU (1) | AU2015287186B2 (pt) |
BR (1) | BR112017000529A2 (pt) |
CA (1) | CA2954086C (pt) |
EA (1) | EA039069B1 (pt) |
MX (1) | MX2017000399A (pt) |
NZ (1) | NZ727876A (pt) |
RU (1) | RU2017104233A (pt) |
TN (1) | TN2017000003A1 (pt) |
WO (1) | WO2016004960A2 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108434110B (zh) * | 2018-04-28 | 2019-09-10 | 浙江仙琚制药股份有限公司 | 米索前列醇组合物、片剂及其用途 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9419566D0 (en) * | 1994-09-27 | 1994-11-16 | El Refaey Hazem | Oral prostagladins for the routine management of the third stage of labour |
IL150053A0 (en) * | 1999-12-06 | 2002-12-01 | Mendell Co Inc Edward | Pharmaceutical superdisintegrant |
GB0204771D0 (en) * | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
TW200502000A (en) * | 2003-03-28 | 2005-01-16 | Kyowa Hakko Kogyo Kk | Dividing tablet |
WO2006125450A1 (en) | 2005-05-26 | 2006-11-30 | Atef Mohammed Mostafa Darwish | Rectal and vaginal suppositories containing misoprostol |
US20060286172A1 (en) | 2005-06-03 | 2006-12-21 | Anu Mahashabde | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
WO2007052289A2 (en) * | 2005-07-22 | 2007-05-10 | Rubicon Research Pvt Ltd. | Novel dispersible tablet composition |
US8148560B2 (en) * | 2005-09-23 | 2012-04-03 | Teva Women's Health, Inc. | Vaginal tablets comprising misoprostol and methods of making and using the same |
US7799530B2 (en) | 2005-09-23 | 2010-09-21 | Celera Corporation | Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof |
KR101626873B1 (ko) * | 2007-10-01 | 2016-06-02 | 라보라토리오스 레스비, 에스.엘. | 구강붕해정제 |
WO2009154810A2 (en) * | 2008-02-25 | 2009-12-23 | Dr. Reddy's Laboratories Ltd. | Delivery systems for multiple active agents |
CN102697746B (zh) * | 2012-06-11 | 2014-03-19 | 广州朗圣药业有限公司 | 一种快速融变的米索前列醇阴道用组合物及其制备方法和应用 |
WO2014016394A1 (en) | 2012-07-26 | 2014-01-30 | Ferring B.V. | Misprostol composition |
CN102872024B (zh) * | 2012-09-28 | 2015-06-17 | 天津市聚星康华医药科技有限公司 | 口腔内使用的米索前列醇药物组合物 |
CN103340837B (zh) * | 2013-07-08 | 2018-04-27 | 天津市聚星康华医药科技有限公司 | 一种米索前列醇阴道泡腾片及其制备方法 |
-
2015
- 2015-07-10 EP EP15750921.7A patent/EP3166597A2/en active Pending
- 2015-07-10 BR BR112017000529A patent/BR112017000529A2/pt not_active Application Discontinuation
- 2015-07-10 CA CA2954086A patent/CA2954086C/en active Active
- 2015-07-10 WO PCT/DK2015/050216 patent/WO2016004960A2/en active Application Filing
- 2015-07-10 NZ NZ727876A patent/NZ727876A/en unknown
- 2015-07-10 JP JP2017521290A patent/JP6532529B2/ja active Active
- 2015-07-10 TN TN2017000003A patent/TN2017000003A1/en unknown
- 2015-07-10 AU AU2015287186A patent/AU2015287186B2/en active Active
- 2015-07-10 MX MX2017000399A patent/MX2017000399A/es unknown
- 2015-07-10 EA EA201692536A patent/EA039069B1/ru unknown
- 2015-07-10 RU RU2017104233A patent/RU2017104233A/ru not_active Application Discontinuation
-
2019
- 2019-05-20 JP JP2019094296A patent/JP6921894B2/ja active Active
-
2020
- 2020-05-08 US US16/870,556 patent/US11406615B2/en active Active
-
2022
- 2022-07-11 US US17/861,711 patent/US20220347145A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6921894B2 (ja) | 2021-08-18 |
AU2015287186B2 (en) | 2018-05-31 |
US20210322356A1 (en) | 2021-10-21 |
CA2954086A1 (en) | 2016-01-14 |
AU2015287186A1 (en) | 2017-01-19 |
NZ727876A (en) | 2018-05-25 |
TN2017000003A1 (en) | 2018-07-04 |
WO2016004960A2 (en) | 2016-01-14 |
EA039069B1 (ru) | 2021-11-30 |
JP2017520628A (ja) | 2017-07-27 |
CA2954086C (en) | 2020-03-31 |
JP2019147831A (ja) | 2019-09-05 |
EP3166597A2 (en) | 2017-05-17 |
MX2017000399A (es) | 2017-08-10 |
RU2017104233A3 (pt) | 2018-12-18 |
JP6532529B2 (ja) | 2019-06-19 |
WO2016004960A3 (en) | 2016-03-17 |
US20220347145A1 (en) | 2022-11-03 |
EA201692536A1 (ru) | 2017-06-30 |
RU2017104233A (ru) | 2018-08-13 |
US11406615B2 (en) | 2022-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |