MXPA02005562A - Superdesintegrante farmaceutico. - Google Patents
Superdesintegrante farmaceutico.Info
- Publication number
- MXPA02005562A MXPA02005562A MXPA02005562A MXPA02005562A MXPA02005562A MX PA02005562 A MXPA02005562 A MX PA02005562A MX PA02005562 A MXPA02005562 A MX PA02005562A MX PA02005562 A MXPA02005562 A MX PA02005562A MX PA02005562 A MXPA02005562 A MX PA02005562A
- Authority
- MX
- Mexico
- Prior art keywords
- superdisintegrant
- superdisintegrants
- dosage form
- solid dosage
- compactibility
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen superdesintegrantes los cuales proporcionan compresabilidad mejorada en comparacion con los superdesintegrantes de la tecnica anterior que no tienen un impacto negativo sobre la compresabilidad de formulaciones que incluyen farmacos en altas dosis, y metodos para obtener los mismos. Los superdesintegrantes incluyen un aglomerado particulado de almidon o celulosa coprocesada y una cantidad suficiente de un agente aditivo para incrementar la compactabilidad del superdesintegrante. El superdesintegrante aumentado proporciona una desintegracion rapida de una forma de desintegracion solida cuando se incorpora en una cantidad suficiente homologa, sin afectar de manera adversa la compactabilidad de la forma de dosificacion solida (en relacion a una forma de dosificacion solida sin el superdesintegrante).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16917499P | 1999-12-06 | 1999-12-06 | |
PCT/US2000/032989 WO2001039746A1 (en) | 1999-12-06 | 2000-12-06 | Pharmaceutical superdisintegrant |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02005562A true MXPA02005562A (es) | 2004-09-10 |
Family
ID=22614504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02005562A MXPA02005562A (es) | 1999-12-06 | 2000-12-06 | Superdesintegrante farmaceutico. |
Country Status (11)
Country | Link |
---|---|
US (2) | US6660303B2 (es) |
EP (1) | EP1244428A1 (es) |
KR (1) | KR20020062323A (es) |
AU (2) | AU771440B2 (es) |
BR (1) | BR0016482A (es) |
CA (1) | CA2393231A1 (es) |
HU (1) | HUP0301333A3 (es) |
IL (1) | IL150053A0 (es) |
MX (1) | MXPA02005562A (es) |
NO (1) | NO20022645L (es) |
WO (1) | WO2001039746A1 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0204771D0 (en) * | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
AU2003256284A1 (en) * | 2002-06-20 | 2004-01-06 | Orapharma, Inc. | Rapidly disintegrating formulations for treating or preventing mucositis |
SI21221A (sl) * | 2002-06-21 | 2003-12-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Hitro razpadljive tablete |
US20040265375A1 (en) * | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
MXPA06006586A (es) * | 2003-12-09 | 2007-02-21 | Pharmasset Inc | Metodos de dosificacion para la terapia antiviral con beta-d-2',3'-didesoxi-2',3'-dideshidro-5-fluorocitidina. |
EP1725217B1 (en) * | 2004-03-10 | 2008-08-06 | Ranbaxy Laboratories, Ltd. | Processes for the preparation of solid dosage forms of amorphous valganciclovir hydrochloride |
US20050220865A1 (en) * | 2004-04-02 | 2005-10-06 | Koleng John J | Compressed composition comprising magnesium salt |
JP2007532623A (ja) * | 2004-04-12 | 2007-11-15 | ファイザー・プロダクツ・インク | 破裂型多重粒子中の味マスキング薬物 |
ES2675581T3 (es) | 2005-02-25 | 2018-07-11 | Takeda Pharmaceutical Company Limited | Método para producir gránulos de un compuesto de bencimidazol recubiertos |
US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
JP2009501801A (ja) * | 2005-07-18 | 2009-01-22 | ホライゾン セラピューティクス, インコーポレイテッド | イブプロフェンとファモチジンとを含有する医薬およびその投与 |
US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
US10357462B2 (en) * | 2006-11-30 | 2019-07-23 | Ben Research, Inc. | Multiparticulates of spray-coated drug and polymer on a meltable core |
US11116728B2 (en) | 2006-11-30 | 2021-09-14 | Bend Research, Inc. | Multiparticulates of spray-coated drug and polymer on a meltable core |
WO2008079343A2 (en) * | 2006-12-21 | 2008-07-03 | Mallinckrodt Inc. | Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients |
ES2758624T3 (es) * | 2009-02-12 | 2020-05-06 | Fuji Chem Ind Co Ltd | Composición de partículas desintegrantes y material de desintegración rápida moldeado por compresión que comprende la misma |
WO2010107507A1 (en) * | 2009-03-20 | 2010-09-23 | Incube Labs, Llc | Solid drug delivery apparatus, formulations and methods of use |
US20100285164A1 (en) * | 2009-05-11 | 2010-11-11 | Jrs Pharma | Orally Disintegrating Excipient |
US20160008310A1 (en) * | 2014-07-11 | 2016-01-14 | Azanta A/S | Misoprostol dispersible tablet |
CA2954086C (en) * | 2014-07-11 | 2020-03-31 | Azanta Danmark A/S | Misoprostol dispersible tablet |
WO2021174188A1 (en) * | 2020-02-27 | 2021-09-02 | Henkel IP & Holding GmbH | A personal care product and a method for making a personal care product by an additive process |
CN112618503B (zh) * | 2021-01-20 | 2022-04-15 | 天津市中央药业有限公司 | 头孢地尼分散片 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3141875A (en) | 1961-03-15 | 1964-07-21 | Fmc Corp | Crystallite aggregates disintegrated in acid medium |
GB2042888B (en) * | 1979-03-05 | 1983-09-28 | Teijin Ltd | Preparation for administration to the mucosa of the oral or nasal cavity |
US4772473A (en) * | 1986-06-16 | 1988-09-20 | Norwich Eaton Pharmaceuticals, Inc. | Nitrofurantoin dosage form |
US4910023A (en) * | 1988-06-09 | 1990-03-20 | Warner-Lambert Company | Drug in combination with flavor masking agent and method for making same |
HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
US5468286A (en) * | 1989-10-25 | 1995-11-21 | National Starch And Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
IT1241417B (it) | 1990-03-06 | 1994-01-14 | Vectorpharma Int | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione |
CA2041774C (en) | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
US5215757A (en) | 1991-03-22 | 1993-06-01 | The Procter & Gamble Company | Encapsulated materials |
US5272191A (en) | 1991-08-21 | 1993-12-21 | Fmc Corporation | Cold water soluble films and film forming compositions |
JP3647859B2 (ja) | 1992-07-24 | 2005-05-18 | ラボファーム・インコーポレーテッド | 酵素的に制御された薬剤放出のための架橋されたポリヒドロキシ材料 |
US5616343A (en) | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
US5948438A (en) | 1995-01-09 | 1999-09-07 | Edward Mendell Co., Inc. | Pharmaceutical formulations having improved disintegration and/or absorptivity |
IL139728A (en) | 1995-01-09 | 2003-06-24 | Penwest Pharmaceuticals Compan | Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient |
US6106865A (en) | 1995-01-09 | 2000-08-22 | Edward Mendell Co., Inc. | Pharmaceutical excipient having improved compressibility |
US5585115A (en) | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
US5733578A (en) | 1995-11-15 | 1998-03-31 | Edward Mendell Co., Inc. | Directly compressible high load acetaminophen formulations |
TW430561B (en) * | 1995-12-20 | 2001-04-21 | Gea Farmaceutisk Fabrik As | Rapid release tablet composition comprising tolfenamic acid or a pharmaceutically acceptable salt thereof as active ingredient and a method of preparing such tablet |
US5989589A (en) | 1997-10-24 | 1999-11-23 | Cartilier; Louis | Cross-linked cellulose as a tablet excipient |
-
2000
- 2000-12-06 WO PCT/US2000/032989 patent/WO2001039746A1/en not_active Application Discontinuation
- 2000-12-06 EP EP00983920A patent/EP1244428A1/en not_active Withdrawn
- 2000-12-06 MX MXPA02005562A patent/MXPA02005562A/es unknown
- 2000-12-06 BR BR0016482-8A patent/BR0016482A/pt not_active Application Discontinuation
- 2000-12-06 AU AU20614/01A patent/AU771440B2/en not_active Ceased
- 2000-12-06 US US09/731,238 patent/US6660303B2/en not_active Expired - Fee Related
- 2000-12-06 KR KR1020027007259A patent/KR20020062323A/ko not_active IP Right Cessation
- 2000-12-06 IL IL15005300A patent/IL150053A0/xx unknown
- 2000-12-06 CA CA002393231A patent/CA2393231A1/en not_active Abandoned
- 2000-12-06 HU HU0301333A patent/HUP0301333A3/hu unknown
-
2002
- 2002-06-05 NO NO20022645A patent/NO20022645L/no not_active Application Discontinuation
-
2003
- 2003-10-02 US US10/677,847 patent/US20050100600A1/en not_active Abandoned
-
2004
- 2004-06-10 AU AU2004202515A patent/AU2004202515A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001039746A1 (en) | 2001-06-07 |
US20020068084A1 (en) | 2002-06-06 |
AU2061401A (en) | 2001-06-12 |
US6660303B2 (en) | 2003-12-09 |
KR20020062323A (ko) | 2002-07-25 |
NO20022645L (no) | 2002-08-01 |
IL150053A0 (en) | 2002-12-01 |
CA2393231A1 (en) | 2001-06-07 |
AU771440B2 (en) | 2004-03-25 |
EP1244428A1 (en) | 2002-10-02 |
US20050100600A1 (en) | 2005-05-12 |
HUP0301333A3 (en) | 2005-06-28 |
BR0016482A (pt) | 2002-12-24 |
NO20022645D0 (no) | 2002-06-05 |
HUP0301333A2 (hu) | 2004-05-28 |
AU2004202515A1 (en) | 2004-07-01 |
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