BR112017000529A2 - comprimido dispersível de misoprostol - Google Patents
comprimido dispersível de misoprostolInfo
- Publication number
- BR112017000529A2 BR112017000529A2 BR112017000529A BR112017000529A BR112017000529A2 BR 112017000529 A2 BR112017000529 A2 BR 112017000529A2 BR 112017000529 A BR112017000529 A BR 112017000529A BR 112017000529 A BR112017000529 A BR 112017000529A BR 112017000529 A2 BR112017000529 A2 BR 112017000529A2
- Authority
- BR
- Brazil
- Prior art keywords
- misoprostol
- dispersible tablet
- pharmaceutically acceptable
- acceptable salt
- relates
- Prior art date
Links
- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 title abstract 3
- 229960005249 misoprostol Drugs 0.000 title abstract 3
- 239000007919 dispersible tablet Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 206010036246 Post abortion haemorrhage Diseases 0.000 abstract 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000005070 ripening Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14176821.8A EP2965750B1 (en) | 2014-07-11 | 2014-07-11 | Misoprostol dispersible tablet |
| US14/329,023 US20160008310A1 (en) | 2014-07-11 | 2014-07-11 | Misoprostol dispersible tablet |
| PCT/DK2015/050216 WO2016004960A2 (en) | 2014-07-11 | 2015-07-10 | Misoprostol dispersible tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017000529A2 true BR112017000529A2 (pt) | 2017-11-14 |
Family
ID=53879283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017000529A BR112017000529A2 (pt) | 2014-07-11 | 2015-07-10 | comprimido dispersível de misoprostol |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11406615B2 (enExample) |
| EP (1) | EP3166597B1 (enExample) |
| JP (2) | JP6532529B2 (enExample) |
| AU (1) | AU2015287186B2 (enExample) |
| BR (1) | BR112017000529A2 (enExample) |
| CA (1) | CA2954086C (enExample) |
| DK (1) | DK3166597T3 (enExample) |
| EA (1) | EA039069B1 (enExample) |
| FI (1) | FI3166597T3 (enExample) |
| MX (1) | MX392771B (enExample) |
| NZ (1) | NZ727876A (enExample) |
| PL (1) | PL3166597T3 (enExample) |
| RU (1) | RU2017104233A (enExample) |
| TN (1) | TN2017000003A1 (enExample) |
| WO (1) | WO2016004960A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108434110B (zh) * | 2018-04-28 | 2019-09-10 | 浙江仙琚制药股份有限公司 | 米索前列醇组合物、片剂及其用途 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB994518A (en) | 1962-07-18 | 1965-06-10 | Needle Industries Ltd | Improvements relating to shavers |
| US4301146A (en) * | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
| US4335097A (en) | 1981-01-15 | 1982-06-15 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Stabilized, prostaglandin-containing tablets with controlled rate of solubility, for local use and process for the preparation thereof |
| JPH06199779A (ja) | 1992-06-08 | 1994-07-19 | Newpharma Internatl Corp | トランス−▲δ２▼−１５−デオキシ−１６−ヒドロキシ−１６−メチル−ｐｇ▲ｅ１▼のメチルエステル（ｂ−４０７） |
| EP0574185B1 (en) | 1992-06-08 | 1997-09-03 | Newpharma International Corporation | PGE1 analogs |
| GB9419566D0 (en) * | 1994-09-27 | 1994-11-16 | El Refaey Hazem | Oral prostagladins for the routine management of the third stage of labour |
| US5993856A (en) | 1997-01-24 | 1999-11-30 | Femmepharma | Pharmaceutical preparations and methods for their administration |
| US6228213B1 (en) | 1997-09-19 | 2001-05-08 | University Of Nebraska-Lincoln | Production of microcrystalline cellulose by reactive extrusion |
| US7815937B2 (en) | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
| US6526980B1 (en) | 1999-08-26 | 2003-03-04 | West Virginia University | Cervical drug delivery system |
| KR20020062323A (ko) * | 1999-12-06 | 2002-07-25 | 펜웨스트 파머슈티칼즈 컴파니 | 제약학적 초붕해제 |
| GB2375303A (en) | 2001-05-11 | 2002-11-13 | Medical Res Council | Method of inducing cervical ripening |
| GB0204771D0 (en) * | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
| SI21221A (sl) | 2002-06-21 | 2003-12-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Hitro razpadljive tablete |
| TW200502000A (en) * | 2003-03-28 | 2005-01-16 | Kyowa Hakko Kogyo Kk | Dividing tablet |
| WO2006125450A1 (en) | 2005-05-26 | 2006-11-30 | Atef Mohammed Mostafa Darwish | Rectal and vaginal suppositories containing misoprostol |
| WO2006133048A2 (en) | 2005-06-03 | 2006-12-14 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
| EP1906937B1 (en) * | 2005-07-22 | 2016-10-19 | Rubicon Research Pvt Ltd. | Novel dispersible tablet composition |
| US7799530B2 (en) | 2005-09-23 | 2010-09-21 | Celera Corporation | Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof |
| WO2007035954A2 (en) | 2005-09-23 | 2007-03-29 | Duramed Pharmaceuticals, Inc. | Vaginal tablets comprising misoprostol and methods of making and using the same |
| CN1939308A (zh) | 2005-09-28 | 2007-04-04 | 应圣俊 | 一种米索前列醇栓剂 |
| EP1987820A1 (en) | 2007-05-04 | 2008-11-05 | Christian Fiala, Ph. D. | Slow release misoprostol for obstetric and/or gynaecological applications |
| EP2572705B1 (en) * | 2007-10-01 | 2017-09-13 | Laboratorios Lesvi, S.L. | Orodispersible tablets |
| WO2009154810A2 (en) * | 2008-02-25 | 2009-12-23 | Dr. Reddy's Laboratories Ltd. | Delivery systems for multiple active agents |
| WO2010036878A1 (en) | 2008-09-26 | 2010-04-01 | The Trustees Of Columbia University In The City Of New York | Use of trpv1 receptor agonists in cervical pain and labor |
| US20120077888A1 (en) | 2009-03-26 | 2012-03-29 | Royal College Of Surgeons In Ireland | Orodispersible tablets |
| US20100260825A1 (en) | 2009-04-13 | 2010-10-14 | Nair Madhavan G | Antifolates for the treatment of cardiovascular, inflammatory, neoplastic, autoimmune and related diseases in sublingual dosage units, film strips, or skin patches |
| RU2394814C1 (ru) | 2009-05-22 | 2010-07-20 | Учреждение Российской академии наук Институт органической химии Уфимского научного центра РАН | Средство, представляющее собой этиловый эфир (±)-11,15-дидезокси-16-метил-16-гидроксипростагландина e1, проявляющее утеротоническую активность |
| PL2579866T3 (pl) | 2010-06-11 | 2017-01-31 | Ferring B.V. | Dopochwowe podawanie mizoprostolu |
| CN102302443B (zh) | 2011-09-21 | 2014-04-23 | 天津市聚星康华医药科技有限公司 | 一种米索前列醇阴道缓释栓剂及其制备方法 |
| CN102697746B (zh) * | 2012-06-11 | 2014-03-19 | 广州朗圣药业有限公司 | 一种快速融变的米索前列醇阴道用组合物及其制备方法和应用 |
| EP2689781A1 (en) | 2012-07-26 | 2014-01-29 | Ferring B.V. | Misoprostol composition |
| CN104487077A (zh) | 2012-07-26 | 2015-04-01 | 辉凌公司 | 米索前列醇制剂 |
| KR20150038174A (ko) | 2012-07-26 | 2015-04-08 | 훼링 비.브이. | 미소프로스톨 조성물 |
| EP2689802A1 (en) | 2012-07-26 | 2014-01-29 | Ferring B.V. | Misoprostol formulation |
| CN102872024B (zh) * | 2012-09-28 | 2015-06-17 | 天津市聚星康华医药科技有限公司 | 口腔内使用的米索前列醇药物组合物 |
| CN103040842B (zh) | 2012-12-08 | 2014-11-12 | 浙江圣博康药业有限公司 | 一种前列腺素类药物组合物及其制成的前列腺素类药物栓剂 |
| CN103340837B (zh) * | 2013-07-08 | 2018-04-27 | 天津市聚星康华医药科技有限公司 | 一种米索前列醇阴道泡腾片及其制备方法 |
-
2015
- 2015-07-10 WO PCT/DK2015/050216 patent/WO2016004960A2/en not_active Ceased
- 2015-07-10 RU RU2017104233A patent/RU2017104233A/ru not_active Application Discontinuation
- 2015-07-10 DK DK15750921.7T patent/DK3166597T3/da active
- 2015-07-10 CA CA2954086A patent/CA2954086C/en active Active
- 2015-07-10 JP JP2017521290A patent/JP6532529B2/ja active Active
- 2015-07-10 NZ NZ727876A patent/NZ727876A/en unknown
- 2015-07-10 EP EP15750921.7A patent/EP3166597B1/en active Active
- 2015-07-10 BR BR112017000529A patent/BR112017000529A2/pt not_active Application Discontinuation
- 2015-07-10 FI FIEP15750921.7T patent/FI3166597T3/fi active
- 2015-07-10 PL PL15750921.7T patent/PL3166597T3/pl unknown
- 2015-07-10 TN TN2017000003A patent/TN2017000003A1/en unknown
- 2015-07-10 AU AU2015287186A patent/AU2015287186B2/en active Active
- 2015-07-10 MX MX2017000399A patent/MX392771B/es unknown
- 2015-07-10 EA EA201692536A patent/EA039069B1/ru unknown
-
2019
- 2019-05-20 JP JP2019094296A patent/JP6921894B2/ja active Active
-
2020
- 2020-05-08 US US16/870,556 patent/US11406615B2/en active Active
-
2022
- 2022-07-11 US US17/861,711 patent/US12005041B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016004960A2 (en) | 2016-01-14 |
| JP6532529B2 (ja) | 2019-06-19 |
| CA2954086A1 (en) | 2016-01-14 |
| AU2015287186A1 (en) | 2017-01-19 |
| JP2017520628A (ja) | 2017-07-27 |
| EP3166597A2 (en) | 2017-05-17 |
| WO2016004960A3 (en) | 2016-03-17 |
| RU2017104233A3 (enExample) | 2018-12-18 |
| NZ727876A (en) | 2018-05-25 |
| JP6921894B2 (ja) | 2021-08-18 |
| PL3166597T3 (pl) | 2025-11-17 |
| EA039069B1 (ru) | 2021-11-30 |
| MX392771B (es) | 2025-03-24 |
| FI3166597T3 (fi) | 2025-09-16 |
| DK3166597T3 (en) | 2025-09-01 |
| US12005041B2 (en) | 2024-06-11 |
| CA2954086C (en) | 2020-03-31 |
| AU2015287186B2 (en) | 2018-05-31 |
| RU2017104233A (ru) | 2018-08-13 |
| US20220347145A1 (en) | 2022-11-03 |
| MX2017000399A (es) | 2017-08-10 |
| US20210322356A1 (en) | 2021-10-21 |
| US11406615B2 (en) | 2022-08-09 |
| EP3166597B1 (en) | 2025-08-06 |
| EA201692536A1 (ru) | 2017-06-30 |
| JP2019147831A (ja) | 2019-09-05 |
| TN2017000003A1 (en) | 2018-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |