JP6512759B2 - 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤 - Google Patents

羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤 Download PDF

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JP6512759B2
JP6512759B2 JP2014130142A JP2014130142A JP6512759B2 JP 6512759 B2 JP6512759 B2 JP 6512759B2 JP 2014130142 A JP2014130142 A JP 2014130142A JP 2014130142 A JP2014130142 A JP 2014130142A JP 6512759 B2 JP6512759 B2 JP 6512759B2
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cell
cells
mesenchymal
collagenase
composition
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JP2015061520A (ja
JP2015061520A5 (enExample
Inventor
研一 山原
研一 山原
明彦 田口
明彦 田口
俊裕 相馬
俊裕 相馬
俊介 大西
俊介 大西
小林　明
明 小林
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Hokkaido University
Hyogo Medical University
Kaneka Corp
National Cerebral and Cardiovascular Center
Foundation for Biomedical Research and Innovation
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Hokkaido University
Hyogo Medical University
Kaneka Corp
National Cerebral and Cardiovascular Center
Foundation for Biomedical Research and Innovation
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Application filed by Hokkaido University, Hyogo Medical University, Kaneka Corp, National Cerebral and Cardiovascular Center, Foundation for Biomedical Research and Innovation filed Critical Hokkaido University
Priority to EP14837352.5A priority patent/EP3037523B1/en
Priority to PCT/JP2014/071546 priority patent/WO2015025810A1/ja
Priority to CN201480046241.8A priority patent/CN105765060B/zh
Priority to US14/912,662 priority patent/US10441611B2/en
Publication of JP2015061520A publication Critical patent/JP2015061520A/ja
Publication of JP2015061520A5 publication Critical patent/JP2015061520A5/ja
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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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JP2014130142A 2013-08-19 2014-06-25 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤 Active JP6512759B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2014130142A JP6512759B2 (ja) 2013-08-19 2014-06-25 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤
PCT/JP2014/071546 WO2015025810A1 (ja) 2013-08-19 2014-08-18 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤
CN201480046241.8A CN105765060B (zh) 2013-08-19 2014-08-18 羊膜间充质系细胞组合物的制造方法和冷冻保存方法、以及治疗剂
US14/912,662 US10441611B2 (en) 2013-08-19 2014-08-18 Method for producing amniotic mesenchymal stromal cell composition, method for cryopreserving the same, and therapeutic agent
EP14837352.5A EP3037523B1 (en) 2013-08-19 2014-08-18 Production method and cryopreservation method for amniotic mesenchymal cell composition, and therapeutic agent
US16/508,463 US11389486B2 (en) 2013-08-19 2019-07-11 Method for producing amniotic mesenchymal stromal cell composition, method for cryopreserving the same, and therapeutic agent

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JP2013170008 2013-08-19
JP2013170008 2013-08-19
JP2014130142A JP6512759B2 (ja) 2013-08-19 2014-06-25 羊膜間葉系細胞組成物の製造方法及び凍結保存方法、並びに治療剤

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JP2015061520A JP2015061520A (ja) 2015-04-02
JP2015061520A5 JP2015061520A5 (enExample) 2017-09-14
JP6512759B2 true JP6512759B2 (ja) 2019-05-15

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US (2) US10441611B2 (enExample)
EP (1) EP3037523B1 (enExample)
JP (1) JP6512759B2 (enExample)
CN (1) CN105765060B (enExample)
WO (1) WO2015025810A1 (enExample)

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CN109312302A (zh) * 2015-10-27 2019-02-05 株式会社钟化 包含间充质系干细胞的细胞群的制造方法、间充质系干细胞、细胞群、以及医药组合物
JP6727334B2 (ja) * 2016-02-01 2020-07-22 グリーン・クロス・ラブ・セル・コーポレイション 細胞の凍結保存のための培地組成物およびその使用
EP3564356A4 (en) * 2016-11-04 2020-05-06 The University Of Tokyo SOLUTION FOR THE CRYCON PRESERVATION OF ANIMAL CELLS OR ANIMAL TISSUE, CRYCON PRESERVED PRODUCT AND METHOD FOR THE CRYCON PRESERVATION
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CN110494556B (zh) * 2017-04-03 2024-04-30 株式会社钟化 包含间充质系干细胞的细胞群、其制造方法、以及医药组合物
JP7140752B2 (ja) * 2017-04-03 2022-09-21 株式会社カネカ 胎児付属物由来接着細胞を含む細胞集団とその製造方法、及び医薬組成物
JP7152389B2 (ja) * 2017-04-03 2022-10-12 株式会社カネカ 間葉系幹細胞を含む細胞集団とその製造方法、間葉系幹細胞及び医薬組成物
CN106967675A (zh) * 2017-05-31 2017-07-21 东莞市保莱生物科技有限公司 一种从胎盘中分离提取造血干细胞的方法
WO2019059279A1 (ja) * 2017-09-20 2019-03-28 株式会社カネカ 細胞懸濁液を調製するためのデバイス、システム及び方法
JP7454379B2 (ja) * 2017-12-28 2024-03-22 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
JP7526001B2 (ja) * 2017-12-28 2024-07-31 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
CN108904533A (zh) * 2018-07-04 2018-11-30 卡替（上海）生物技术股份有限公司 牙髓间充质干细胞在制备肝硬化治疗药物中的用途
WO2020184350A1 (ja) 2019-03-08 2020-09-17 株式会社カネカ 多能性幹細胞の大量培養
WO2020251020A1 (ja) * 2019-06-14 2020-12-17 株式会社カネカ 間葉系細胞を含む細胞集団、それを含む医薬組成物、及び、その製造方法
US20230338428A1 (en) * 2020-09-08 2023-10-26 Amit Patel Allogenic umbilical cord stem cells for treating severe respiratory conditions
JP7672647B2 (ja) * 2021-02-05 2025-05-08 株式会社カネカ 間葉系幹細胞を含む細胞集団を含有する軟部組織再生用医薬組成物
WO2022203022A1 (ja) * 2021-03-26 2022-09-29 株式会社カネカ 羊膜由来間葉系幹細胞を含む細胞集団の製造方法
CN113456891B (zh) * 2021-06-16 2022-05-17 成都微沃科技有限公司 一种从细胞层中提取细胞外基质层的方法
CN114097768A (zh) * 2021-11-24 2022-03-01 李敬 一种骨髓干细胞用保护液及其制备方法和应用
WO2025150510A1 (ja) 2024-01-12 2025-07-17 株式会社カネカ 単一の間葉系幹細胞を単離する方法
CN120400046B (zh) * 2025-07-03 2025-10-17 济南万泉生物技术有限公司 一种羊膜基质细胞培养体系、细胞培养方法及应用

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US20160228474A1 (en) 2016-08-11
US11389486B2 (en) 2022-07-19
CN105765060A (zh) 2016-07-13
EP3037523A4 (en) 2017-01-25
JP2015061520A (ja) 2015-04-02
WO2015025810A1 (ja) 2015-02-26
US10441611B2 (en) 2019-10-15
US20190343892A1 (en) 2019-11-14
EP3037523B1 (en) 2020-08-12
CN105765060B (zh) 2020-04-28
EP3037523A1 (en) 2016-06-29

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