JP6511432B2 - Ｃ型肝炎ウイルスの大環状二環式阻害剤 - Google Patents
Ｃ型肝炎ウイルスの大環状二環式阻害剤 Download PDFInfo
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- JP6511432B2 JP6511432B2 JP2016503218A JP2016503218A JP6511432B2 JP 6511432 B2 JP6511432 B2 JP 6511432B2 JP 2016503218 A JP2016503218 A JP 2016503218A JP 2016503218 A JP2016503218 A JP 2016503218A JP 6511432 B2 JP6511432 B2 JP 6511432B2
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- alkyl
- carbocyclyl
- aryl
- optionally substituted
- membered
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
-
- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
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| LT3236972T (lt) | 2014-12-26 | 2021-11-10 | Emory University | Antivirusiniai n4-hidroksicitidino dariniai |
| CN105503751B (zh) * | 2015-12-22 | 2018-06-05 | 广西师范大学 | 一种喹喔啉衍生物的高效合成方法 |
| LT3706762T (lt) | 2017-12-07 | 2024-12-27 | Emory University | N4-hidroksicitidinas ir jo dariniai bei susiję naudojimo prieš virusus būdai |
| CN108329332A (zh) * | 2018-03-16 | 2018-07-27 | 安徽华昌高科药业有限公司 | 一种制备Glecaprevir的方法 |
| CN111004188B (zh) * | 2019-12-18 | 2021-04-20 | 安徽红杉生物医药科技有限公司 | Ns3/4a蛋白酶抑制剂中间体及其合成方法、应用 |
| CN111018795B (zh) * | 2019-12-25 | 2023-03-28 | 上海彩迩文生化科技有限公司 | 一种碱性条件下合成喹喔啉-3-酮的方法 |
| US12083099B2 (en) | 2020-10-28 | 2024-09-10 | Accencio LLC | Methods of treating symptoms of coronavirus infection with viral protease inhibitors |
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2014
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- 2014-03-14 CA CA2902569A patent/CA2902569A1/en not_active Abandoned
- 2014-03-14 WO PCT/US2014/029765 patent/WO2014145095A1/en not_active Ceased
- 2014-03-14 CN CN201480015589.0A patent/CN105073758B/zh active Active
- 2014-03-14 EA EA201591456A patent/EA029088B1/ru not_active IP Right Cessation
- 2014-03-14 KR KR1020157028437A patent/KR102215400B1/ko active Active
- 2014-03-14 SG SG11201507223TA patent/SG11201507223TA/en unknown
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2015
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2017
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2018
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| BR112015021768A2 (pt) | 2016-02-02 |
| EA029088B1 (ru) | 2018-02-28 |
| US9617310B2 (en) | 2017-04-11 |
| IL240662A0 (en) | 2015-10-29 |
| CN105073758A (zh) | 2015-11-18 |
| CA2902569A1 (en) | 2014-09-18 |
| MX2015013224A (es) | 2015-12-11 |
| CN105073758B (zh) | 2017-08-11 |
| HK1217196A1 (en) | 2016-12-30 |
| AU2014233390B2 (en) | 2018-03-01 |
| ES2735355T3 (es) | 2019-12-18 |
| KR20150130456A (ko) | 2015-11-23 |
| US20170313745A1 (en) | 2017-11-02 |
| KR102215400B1 (ko) | 2021-02-10 |
| JP2016516069A (ja) | 2016-06-02 |
| WO2014145095A1 (en) | 2014-09-18 |
| AU2014233390A1 (en) | 2015-09-03 |
| EP2970335B1 (en) | 2019-05-08 |
| EP2970335A1 (en) | 2016-01-20 |
| EA201591456A1 (ru) | 2016-02-29 |
| JP2019059775A (ja) | 2019-04-18 |
| US20140274884A1 (en) | 2014-09-18 |
| SG11201507223TA (en) | 2015-10-29 |
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