JP6463359B2 - 補体関連病態を治療するための組成物及び方法 - Google Patents

補体関連病態を治療するための組成物及び方法 Download PDF

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JP6463359B2
JP6463359B2 JP2016533496A JP2016533496A JP6463359B2 JP 6463359 B2 JP6463359 B2 JP 6463359B2 JP 2016533496 A JP2016533496 A JP 2016533496A JP 2016533496 A JP2016533496 A JP 2016533496A JP 6463359 B2 JP6463359 B2 JP 6463359B2
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snp
allele
polymorphism
seq
antibody
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ブライアン ヤスパン,
ブライアン ヤスパン,
ロバート ロイヤル グレアム,
ロバート ロイヤル グレアム,
エイミー ドレッセン,
エイミー ドレッセン,
チョンロン リー,
チョンロン リー,
エーリヒ シュトラウス,
エーリヒ シュトラウス,
テオドリカ ブガワン,
テオドリカ ブガワン,
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Genentech Inc
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2016533496A 2013-08-12 2014-08-11 補体関連病態を治療するための組成物及び方法 Expired - Fee Related JP6463359B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361864941P 2013-08-12 2013-08-12
US61/864,941 2013-08-12
US201361866651P 2013-08-16 2013-08-16
US61/866,651 2013-08-16
US201361872098P 2013-08-30 2013-08-30
US61/872,098 2013-08-30
US201461988012P 2014-05-02 2014-05-02
US61/988,012 2014-05-02
US201462021487P 2014-07-07 2014-07-07
US62/021,487 2014-07-07
PCT/US2014/050579 WO2015023596A1 (en) 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions

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JP2017222267A Division JP2018064566A (ja) 2013-08-12 2017-09-28 補体関連病態を治療するための組成物及び方法

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JP6463359B2 true JP6463359B2 (ja) 2019-01-30

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JP2017222267A Withdrawn JP2018064566A (ja) 2013-08-12 2017-09-28 補体関連病態を治療するための組成物及び方法
JP2019154149A Pending JP2020028293A (ja) 2013-08-12 2019-07-30 補体関連病態を治療するための組成物及び方法

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JP2019154149A Pending JP2020028293A (ja) 2013-08-12 2019-07-30 補体関連病態を治療するための組成物及び方法

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US (3) US10093978B2 (enExample)
EP (1) EP3033436A1 (enExample)
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KR (2) KR20180021234A (enExample)
CN (1) CN107318267B (enExample)
AU (1) AU2014306867B2 (enExample)
BR (1) BR112016002845A2 (enExample)
CA (1) CA2920666A1 (enExample)
CL (1) CL2016000326A1 (enExample)
CR (1) CR20160132A (enExample)
EA (1) EA201690213A1 (enExample)
IL (1) IL243928A0 (enExample)
MX (1) MX2016001854A (enExample)
PE (1) PE20160192A1 (enExample)
PH (1) PH12016500302A1 (enExample)
SG (1) SG11201601044XA (enExample)
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WO (1) WO2015023596A1 (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2020028293A (ja) * 2013-08-12 2020-02-27 ジェネンテック, インコーポレイテッド 補体関連病態を治療するための組成物及び方法

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JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック, インコーポレイテッド 抗d因子抗体変異体コンジュゲート及びその使用
CA3003647A1 (en) * 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody formulations
CN106885910B (zh) * 2015-12-15 2018-12-21 上海吉涛生物科技有限公司 肿瘤易感微环境检测装置及试剂盒
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CN109706238B (zh) 2017-10-26 2023-04-07 珠海岐微生物科技有限公司 一种老年性黄斑病变的检测与治疗方法
TWI831792B (zh) * 2018-06-12 2024-02-11 合一生技股份有限公司 靶向淋巴細胞活化基因3(lag-3)的核酸適體及其用途
CN109243567B (zh) * 2018-08-14 2021-11-02 山东科技大学 一种基于处方数据挖掘的药物推荐方法
CN109448781B (zh) * 2018-11-06 2021-09-14 云南大学 一种流感病毒抗原变化的预测方法
SG11202105025VA (en) 2018-11-14 2021-06-29 Zhuhai Qiwei Bio Tech Ltd Animal models, screening methods, and treatment methods for intraocular diseases or disorders
US11753382B2 (en) 2019-06-25 2023-09-12 Translatum Medicus Inc. Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
CN114395620B (zh) * 2021-12-20 2022-09-20 温州谱希医学检验实验室有限公司 一种检测高度近视易感人群的生物标志物组合
CN117235479A (zh) * 2023-08-25 2023-12-15 上海金仕达软件科技股份有限公司 目标因子筛选方法及装置

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