AU2014306867B2 - Compositions and method for treating complement-associated conditions - Google Patents

Compositions and method for treating complement-associated conditions Download PDF

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Publication number
AU2014306867B2
AU2014306867B2 AU2014306867A AU2014306867A AU2014306867B2 AU 2014306867 B2 AU2014306867 B2 AU 2014306867B2 AU 2014306867 A AU2014306867 A AU 2014306867A AU 2014306867 A AU2014306867 A AU 2014306867A AU 2014306867 B2 AU2014306867 B2 AU 2014306867B2
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snp
allele
antibody
amd
patient
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AU2014306867A1 (en
Inventor
Teodorica Bugawan
Amy DRESSEN
Robert Royal Graham
Zhengrong Li
Erich STRAUSS
Brian YASPAN
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2014306867A 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions Ceased AU2014306867B2 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361864941P 2013-08-12 2013-08-12
US61/864,941 2013-08-12
US201361866651P 2013-08-16 2013-08-16
US61/866,651 2013-08-16
US201361872098P 2013-08-30 2013-08-30
US61/872,098 2013-08-30
US201461988012P 2014-05-02 2014-05-02
US61/988,012 2014-05-02
US201462021487P 2014-07-07 2014-07-07
US62/021,487 2014-07-07
PCT/US2014/050579 WO2015023596A1 (en) 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018200531A Division AU2018200531A1 (en) 2013-08-12 2018-01-23 Compositions and method for treating complement-associated conditions

Publications (2)

Publication Number Publication Date
AU2014306867A1 AU2014306867A1 (en) 2016-03-10
AU2014306867B2 true AU2014306867B2 (en) 2017-10-26

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AU2014306867A Ceased AU2014306867B2 (en) 2013-08-12 2014-08-11 Compositions and method for treating complement-associated conditions

Country Status (18)

Country Link
US (3) US10093978B2 (enExample)
EP (1) EP3033436A1 (enExample)
JP (3) JP6463359B2 (enExample)
KR (2) KR20180021234A (enExample)
CN (1) CN107318267B (enExample)
AU (1) AU2014306867B2 (enExample)
BR (1) BR112016002845A2 (enExample)
CA (1) CA2920666A1 (enExample)
CL (1) CL2016000326A1 (enExample)
CR (1) CR20160132A (enExample)
EA (1) EA201690213A1 (enExample)
IL (1) IL243928A0 (enExample)
MX (1) MX2016001854A (enExample)
PE (1) PE20160192A1 (enExample)
PH (1) PH12016500302A1 (enExample)
SG (1) SG11201601044XA (enExample)
TW (1) TWI656217B (enExample)
WO (1) WO2015023596A1 (enExample)

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US10093978B2 (en) 2013-08-12 2018-10-09 Genentech, Inc. Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
AU2015253042A1 (en) 2014-05-01 2016-10-20 Genentech, Inc. Anti-factor D antibody variants and uses thereof
US10407510B2 (en) 2015-10-30 2019-09-10 Genentech, Inc. Anti-factor D antibodies and conjugates
JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体変異体コンジュゲート及びその使用
CA3003647A1 (en) * 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody formulations
CN106885910B (zh) * 2015-12-15 2018-12-21 上海吉涛生物科技有限公司 肿瘤易感微环境检测装置及试剂盒
CA3011819A1 (en) 2016-01-20 2017-07-27 Vitrisa Therapeutics, Inc. Compositions and methods for inhibiting factor d
WO2018136827A1 (en) 2017-01-20 2018-07-26 Vitrisa Therapeutics, Inc. Stem-loop compositions and methods for inhibiting factor d
CN109706238B (zh) 2017-10-26 2023-04-07 珠海岐微生物科技有限公司 一种老年性黄斑病变的检测与治疗方法
TWI831792B (zh) * 2018-06-12 2024-02-11 合一生技股份有限公司 靶向淋巴細胞活化基因3(lag-3)的核酸適體及其用途
CN109243567B (zh) * 2018-08-14 2021-11-02 山东科技大学 一种基于处方数据挖掘的药物推荐方法
CN109448781B (zh) * 2018-11-06 2021-09-14 云南大学 一种流感病毒抗原变化的预测方法
SG11202105025VA (en) 2018-11-14 2021-06-29 Zhuhai Qiwei Bio Tech Ltd Animal models, screening methods, and treatment methods for intraocular diseases or disorders
US11753382B2 (en) 2019-06-25 2023-09-12 Translatum Medicus Inc. Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
CN114395620B (zh) * 2021-12-20 2022-09-20 温州谱希医学检验实验室有限公司 一种检测高度近视易感人群的生物标志物组合
CN117235479A (zh) * 2023-08-25 2023-12-15 上海金仕达软件科技股份有限公司 目标因子筛选方法及装置

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