BRPI0811007A2 - Tratamento de degeneração macular relacionada à idade usando inibidores de fator de complemento d - Google Patents

Tratamento de degeneração macular relacionada à idade usando inibidores de fator de complemento d

Info

Publication number
BRPI0811007A2
BRPI0811007A2 BRPI0811007-7A2A BRPI0811007A BRPI0811007A2 BR PI0811007 A2 BRPI0811007 A2 BR PI0811007A2 BR PI0811007 A BRPI0811007 A BR PI0811007A BR PI0811007 A2 BRPI0811007 A2 BR PI0811007A2
Authority
BR
Brazil
Prior art keywords
age
treatment
macular degeneration
related macular
factor inhibitors
Prior art date
Application number
BRPI0811007-7A2A
Other languages
English (en)
Inventor
Carmelo Romano
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of BRPI0811007A2 publication Critical patent/BRPI0811007A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
BRPI0811007-7A2A 2007-04-30 2008-04-07 Tratamento de degeneração macular relacionada à idade usando inibidores de fator de complemento d BRPI0811007A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91487707P 2007-04-30 2007-04-30
PCT/US2008/059556 WO2008137236A2 (en) 2007-04-30 2008-04-07 Treatment of age-related macular degeneration using inhibitors of complement factor d

Publications (1)

Publication Number Publication Date
BRPI0811007A2 true BRPI0811007A2 (pt) 2015-01-27

Family

ID=39586997

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0811007-7A2A BRPI0811007A2 (pt) 2007-04-30 2008-04-07 Tratamento de degeneração macular relacionada à idade usando inibidores de fator de complemento d

Country Status (15)

Country Link
US (1) US20080269318A1 (pt)
EP (1) EP2139471A2 (pt)
JP (1) JP2010526074A (pt)
KR (1) KR20100014486A (pt)
CN (1) CN101674824A (pt)
AR (1) AR066292A1 (pt)
AU (1) AU2008248043A1 (pt)
BR (1) BRPI0811007A2 (pt)
CA (1) CA2680833A1 (pt)
CL (1) CL2008001259A1 (pt)
MX (1) MX2009009738A (pt)
RU (1) RU2009144142A (pt)
TW (1) TW200900056A (pt)
UY (1) UY31061A1 (pt)
WO (1) WO2008137236A2 (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316394B1 (en) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
ES2747755T3 (es) 2009-01-29 2020-03-11 Forsight Vision4 Inc Administración de un fármaco al segmento posterior
SI2600930T1 (sl) 2010-08-05 2021-08-31 Forsight Vision4, Inc. Injekcijska naprava za dajanje zdravila
CN103209664A (zh) * 2010-08-05 2013-07-17 弗赛特影像4股份有限公司 可植入的治疗装置
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
EP2739252A4 (en) 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
RU2495650C1 (ru) * 2012-02-29 2013-10-20 Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации Трехкомпонентный комплекс для клеточной терапии в офтальмологии
RU2485922C1 (ru) * 2012-03-28 2013-06-27 Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации Способ лечения "сухой" формы возрастной макулярной дегенерации
RU2494711C1 (ru) * 2012-05-18 2013-10-10 Федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения и социального развития Российской Федерации Способ хирургического лечения прогрессирующей и осложненной миопии
CA2905496A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
JP6385423B2 (ja) 2013-03-28 2018-09-05 フォーサイト・ビジョン フォー・インコーポレーテッド 治療物質送達用の眼移植片
JP6463359B2 (ja) * 2013-08-12 2019-01-30 ジェネンテック， インコーポレイテッド 補体関連病態を治療するための組成物及び方法
US10518002B2 (en) 2013-09-06 2019-12-31 The Regents Of The University Of Colorado, A Body Corporate Intraocular drug delivery and filter device and methods of using same
US11219552B2 (en) 2013-09-06 2022-01-11 The Regents Of The University Of Colorado, A Body Corporate Intraocular filter device and methods of using same
US20160237146A1 (en) * 2013-10-07 2016-08-18 Massachusetts Eye And Ear Infirmary Methods of Preventing or Reducing Photoreceptor Cell Death
DE102014107380A1 (de) 2014-05-26 2015-11-26 Eberhard Karls Universität Tübingen Medizinische Fakultät Verfahren zur Diagnose einer durch den alternativen Weg des Komplementsystems vermittelten Krankheit oder eines Risikos hierfür
CA2949985C (en) 2014-06-12 2023-10-17 Ra Pharmaceuticals, Inc. Modulation of complement activity
MY182793A (en) 2014-08-08 2021-02-05 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US9937222B2 (en) 2015-01-28 2018-04-10 Ra Pharmaceuticals, Inc. Modulators of complement activity
KR20180084104A (ko) 2015-11-20 2018-07-24 포사이트 비젼4, 인크. 연장 방출 약물 전달 장치를 위한 다공성 구조물
KR20180094913A (ko) 2015-12-16 2018-08-24 라 파마슈티컬스 인코포레이티드 보체 활성의 조절인자
CN108934169A (zh) 2016-01-20 2018-12-04 维特里萨医疗公司 用于抑制因子d的组合物和方法
JP7301741B2 (ja) 2016-12-07 2023-07-03 ラ ファーマシューティカルズ インコーポレイテッド 補体活性のモジュレータ
WO2018136827A1 (en) 2017-01-20 2018-07-26 Vitrisa Therapeutics, Inc. Stem-loop compositions and methods for inhibiting factor d
EP3610010A4 (en) * 2017-04-14 2021-02-24 Kodiak Sciences Inc. COMPLEMENT D-FACTOR ANTAGONIST ANTIBODIES AND THEIR CONJUGATES
KR20200095485A (ko) 2017-12-04 2020-08-10 라 파마슈티컬스 인코포레이티드 보체 활성의 조절인자
WO2020185541A2 (en) 2019-03-08 2020-09-17 Ra Pharmaceuticals, Inc. Modulators of complement activity
US20230115176A1 (en) 2019-03-29 2023-04-13 Ra Pharmaceuticals, Inc. Complement Modulators and Related Methods
AU2020261059A1 (en) 2019-04-24 2021-10-14 Ra Pharmaceuticals, Inc. Compositions and methods for modulating complement activity
EP4041312A4 (en) 2019-10-10 2023-12-20 Kodiak Sciences Inc. METHOD FOR TREATING AN EYE DISORDER
MX2022014275A (es) 2020-05-12 2022-12-07 Alexion Pharma Inc Uso de inhibidores del factor d del complemento solos o junto con anticuerpos anti-c5 para el tratamiento de la hemoglobinuria paroxistica nocturna.
CN114686481B (zh) * 2020-12-31 2023-08-15 北京键凯科技股份有限公司 一种抑制cfd表达的干扰rna及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7808198A (en) * 1997-06-03 1998-12-21 Biocryst Pharmaceuticals, Inc. Novel compounds useful in the complement, coagulat and kallikrein pathways and method for their preparation
AU775149B2 (en) * 1999-10-21 2004-07-22 Alcon Inc. Sub-tenon drug delivery
DK2026073T3 (en) * 2000-04-29 2016-07-25 Univ Iowa Res Found Diagnosis and treatment of macular degeneration-related disorders
ATE526421T1 (de) * 2005-02-14 2011-10-15 Univ Iowa Res Found Verfahren und reagenzien zur behandlung und diagnose von altersbedingter makuladegeneration
AU2008214359B2 (en) * 2007-02-05 2014-01-16 Apellis Pharmaceuticals, Inc. Local complement inhibition for treatment of complement-mediated disorders

Also Published As

Publication number Publication date
CL2008001259A1 (es) 2009-01-02
EP2139471A2 (en) 2010-01-06
WO2008137236A3 (en) 2009-02-05
KR20100014486A (ko) 2010-02-10
RU2009144142A (ru) 2011-06-10
AU2008248043A1 (en) 2008-11-13
TW200900056A (en) 2009-01-01
CA2680833A1 (en) 2008-11-13
AR066292A1 (es) 2009-08-12
CN101674824A (zh) 2010-03-17
US20080269318A1 (en) 2008-10-30
WO2008137236A2 (en) 2008-11-13
UY31061A1 (es) 2008-10-31
JP2010526074A (ja) 2010-07-29
MX2009009738A (es) 2009-09-24

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]