BR112013010769A2 - predição de progressão para degeneração macular relacionada à idade avançada usando um escore poligênico - Google Patents
predição de progressão para degeneração macular relacionada à idade avançada usando um escore poligênicoInfo
- Publication number
- BR112013010769A2 BR112013010769A2 BR112013010769A BR112013010769A BR112013010769A2 BR 112013010769 A2 BR112013010769 A2 BR 112013010769A2 BR 112013010769 A BR112013010769 A BR 112013010769A BR 112013010769 A BR112013010769 A BR 112013010769A BR 112013010769 A2 BR112013010769 A2 BR 112013010769A2
- Authority
- BR
- Brazil
- Prior art keywords
- progression
- prediction
- macular degeneration
- related macular
- advanced age
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40903910P | 2010-11-01 | 2010-11-01 | |
| US201161573602P | 2011-09-09 | 2011-09-09 | |
| PCT/US2011/058829 WO2012061421A1 (en) | 2010-11-01 | 2011-11-01 | Predicting progression to advanced age-related macular degeneration using a polygenic score |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013010769A2 true BR112013010769A2 (pt) | 2019-09-24 |
Family
ID=45002128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013010769A BR112013010769A2 (pt) | 2010-11-01 | 2011-11-01 | predição de progressão para degeneração macular relacionada à idade avançada usando um escore poligênico |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US20120107315A1 (pt) |
| EP (2) | EP3170905A1 (pt) |
| JP (4) | JP2013544512A (pt) |
| KR (1) | KR20130130732A (pt) |
| CN (1) | CN103201393B (pt) |
| AR (1) | AR083677A1 (pt) |
| AU (2) | AU2011323487B2 (pt) |
| BR (1) | BR112013010769A2 (pt) |
| CA (1) | CA2816805A1 (pt) |
| DK (1) | DK2635704T3 (pt) |
| ES (1) | ES2628806T3 (pt) |
| HU (1) | HUE032938T2 (pt) |
| IL (1) | IL226063A0 (pt) |
| MX (1) | MX348025B (pt) |
| NZ (1) | NZ610067A (pt) |
| PL (1) | PL2635704T3 (pt) |
| RU (2) | RU2593954C2 (pt) |
| SG (2) | SG10201605904PA (pt) |
| SI (1) | SI2635704T1 (pt) |
| TW (1) | TW201250003A (pt) |
| WO (1) | WO2012061421A1 (pt) |
| ZA (1) | ZA201303001B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2883245A1 (en) * | 2012-09-06 | 2014-03-13 | Ancestry.Com Dna, Llc | Using haplotypes to infer ancestral origins for recently admixed individuals |
| US9737205B2 (en) | 2013-07-31 | 2017-08-22 | The Board Of Trustees Of The Leland Stanford Junior University | Method and system for evaluating progression of age-related macular degeneration |
| KR20160042438A (ko) | 2013-08-12 | 2016-04-19 | 제넨테크, 인크. | 보체-연관 상태의 치료를 위한 조성물 및 방법 |
| TW201623337A (zh) | 2014-05-01 | 2016-07-01 | 建南德克公司 | 抗－因子ｄ抗體變異體及其用途 |
| RU2559090C1 (ru) * | 2014-08-27 | 2015-08-10 | Александр Владимирович Кулик | Способ прогнозирования персонифицированного риска развития макулодистрофии |
| EP3368090A1 (en) | 2015-10-30 | 2018-09-05 | H. Hoffnabb-La Roche Ag | Anti-factor d antibody variant conjugates and uses thereof |
| WO2017075173A2 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibodies and conjugates |
| EP3405577B8 (en) | 2016-01-20 | 2023-02-15 | 396419 B.C. Ltd. | Compositions and methods for inhibiting factor d |
| CN106086222A (zh) * | 2016-08-24 | 2016-11-09 | 厦门美因生物科技有限公司 | 基于qPCR分型技术的运动基因检测评估方法及系统 |
| WO2018078631A1 (en) * | 2016-10-30 | 2018-05-03 | Taliaz Ltd. | Method and system for predicting response of a subject to antidepressant treatment |
| WO2018136827A1 (en) | 2017-01-20 | 2018-07-26 | Vitrisa Therapeutics, Inc. | Stem-loop compositions and methods for inhibiting factor d |
| WO2018209222A1 (en) * | 2017-05-12 | 2018-11-15 | Massachusetts Institute Of Technology | Systems and methods for crowdsourcing, analyzing, and/or matching personal data |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| CN109585017B (zh) * | 2019-01-31 | 2023-12-12 | 上海宝藤生物医药科技股份有限公司 | 一种年龄相关性黄斑变性的风险预测算法模型和装置 |
| WO2022010273A1 (ko) * | 2020-07-07 | 2022-01-13 | 주식회사 카나프테라퓨틱스 | 보체 경로 억제제를 포함하는 융합단백질 및 이의 용도 |
| RU2758662C1 (ru) * | 2021-03-19 | 2021-11-01 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Минздрава России) | Способ определения показаний к антиангиогенной терапии при подозрении на влажную форму возрастной макулярной дегенерации |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| AU746549B2 (en) * | 1996-11-20 | 2002-05-02 | Becton Dickinson & Company | Microfabricated isothermal nucleic acid amplification devices and methods |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| US6956107B2 (en) | 1998-02-20 | 2005-10-18 | Tanox, Inc. | Inhibitors of complement activation |
| US7112327B2 (en) | 1998-02-20 | 2006-09-26 | Tanox, Inc. | Inhibition of complement activation |
| CA2439735A1 (en) | 2001-03-14 | 2002-09-19 | Genentech, Inc. | Igf antagonist peptides |
| RU2186392C1 (ru) * | 2001-04-26 | 2002-07-27 | Должич Галина Ивановна | Способ диагностики сенильной макулярной дистрофии сетчатки |
| US7758859B2 (en) | 2003-08-01 | 2010-07-20 | Genentech, Inc. | Anti-VEGF antibodies |
| CN1950826A (zh) * | 2004-03-05 | 2007-04-18 | 佩勒根科学有限公司 | 遗传分析的方法 |
| US7127355B2 (en) * | 2004-03-05 | 2006-10-24 | Perlegen Sciences, Inc. | Methods for genetic analysis |
| US7527970B2 (en) | 2004-10-15 | 2009-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Method of identifying active chromatin domains |
| EP1833994A4 (en) * | 2005-01-04 | 2009-09-02 | Hitachi Chemical Co Ltd | ROLLING CIRCLE GAINING OF A PRIMER GENERATION |
| EP2357254A1 (en) * | 2005-02-14 | 2011-08-17 | University of Iowa Research Foundation | Methods and reagents for treatment and diagnosis of age-related macular degeneration |
| AU2006254979B2 (en) * | 2005-06-08 | 2011-11-24 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Susceptibility genes for age-related maculopathy (ARM) on chromosome 10q26 |
| HUE026423T2 (en) | 2005-11-04 | 2016-05-30 | Genentech Inc | Use of complement biosynthetic pathway inhibitors for treating eye diseases |
| US20080146501A1 (en) * | 2006-02-13 | 2008-06-19 | University Of Iowa Research Foundation | Protective complement proteins and age-related macular degeneration |
| JP2010526555A (ja) * | 2007-05-11 | 2010-08-05 | タフツ・メディカル・センター | 加齢関連黄斑変性と関係するポリヌクレオチド及び患者のリスクを評価する方法 |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| WO2009029587A2 (en) * | 2007-08-24 | 2009-03-05 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating macular degeneration |
| US20110177957A1 (en) * | 2008-04-18 | 2011-07-21 | Tufts Medical Center, Inc., (f/k/a/ New England Medical Center Hospitals, Inc.) | Polymorphisms Associated With Age-Related Macular Degeneration And Methods For Evaluating Patient Risk |
| AT506998B1 (de) * | 2008-06-30 | 2010-03-15 | Fronius Int Gmbh | Kontaktrohr für einen schweissbrenner |
| US20120115925A1 (en) * | 2008-12-23 | 2012-05-10 | Massachusetts Eye And Ear Infirmary | Allelic Variants Associated with Advanced Age-Related Macular Degeneration |
| WO2010085542A2 (en) * | 2009-01-23 | 2010-07-29 | Novartis Ag | Biomarkers related to age-related macular degeneration (amd) |
-
2011
- 2011-11-01 SG SG10201605904PA patent/SG10201605904PA/en unknown
- 2011-11-01 JP JP2013536932A patent/JP2013544512A/ja not_active Withdrawn
- 2011-11-01 SG SG2013033337A patent/SG190078A1/en unknown
- 2011-11-01 CN CN201180052312.1A patent/CN103201393B/zh not_active Expired - Fee Related
- 2011-11-01 MX MX2013004879A patent/MX348025B/es active IP Right Grant
- 2011-11-01 AU AU2011323487A patent/AU2011323487B2/en not_active Ceased
- 2011-11-01 CA CA2816805A patent/CA2816805A1/en not_active Abandoned
- 2011-11-01 KR KR1020137014161A patent/KR20130130732A/ko not_active Application Discontinuation
- 2011-11-01 SI SI201131208A patent/SI2635704T1/sl unknown
- 2011-11-01 ES ES11785527.0T patent/ES2628806T3/es active Active
- 2011-11-01 HU HUE11785527A patent/HUE032938T2/hu unknown
- 2011-11-01 DK DK11785527.0T patent/DK2635704T3/en active
- 2011-11-01 RU RU2013125230/10A patent/RU2593954C2/ru not_active IP Right Cessation
- 2011-11-01 AR ARP110104052A patent/AR083677A1/es unknown
- 2011-11-01 RU RU2016127684A patent/RU2016127684A/ru unknown
- 2011-11-01 NZ NZ610067A patent/NZ610067A/en not_active IP Right Cessation
- 2011-11-01 WO PCT/US2011/058829 patent/WO2012061421A1/en active Application Filing
- 2011-11-01 EP EP16193134.0A patent/EP3170905A1/en not_active Withdrawn
- 2011-11-01 EP EP11785527.0A patent/EP2635704B1/en active Active
- 2011-11-01 TW TW100139739A patent/TW201250003A/zh unknown
- 2011-11-01 BR BR112013010769A patent/BR112013010769A2/pt not_active IP Right Cessation
- 2011-11-01 US US13/317,949 patent/US20120107315A1/en not_active Abandoned
- 2011-11-01 PL PL11785527T patent/PL2635704T3/pl unknown
-
2013
- 2013-04-24 ZA ZA2013/03001A patent/ZA201303001B/en unknown
- 2013-04-30 IL IL226063A patent/IL226063A0/en unknown
-
2014
- 2014-03-04 US US13/999,496 patent/US20140286947A1/en not_active Abandoned
-
2016
- 2016-02-16 JP JP2016027382A patent/JP2016154538A/ja active Pending
- 2016-11-08 AU AU2016256692A patent/AU2016256692A1/en not_active Abandoned
-
2017
- 2017-07-18 US US15/653,460 patent/US20180163262A1/en not_active Abandoned
- 2017-10-19 JP JP2017202311A patent/JP2018068285A/ja not_active Withdrawn
-
2019
- 2019-08-02 JP JP2019143107A patent/JP2019216732A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112013010769A2 (pt) | predição de progressão para degeneração macular relacionada à idade avançada usando um escore poligênico | |
| MA35423B1 (fr) | Composés de cyclopropanamine | |
| CO6910194A2 (es) | Procesos e intemediarios para preparar un inhibidor de jak | |
| BR112014007782A2 (pt) | compostos para transdução viral aperfeiçoada | |
| IL231425B (en) | Solid formulations of anthelmintic sulfonamides | |
| BR112013018900A2 (pt) | conjuntos para uma estrutura | |
| BR112014006702A2 (pt) | método para tratar osteoporose | |
| BR112014012414A2 (pt) | processo para a preparação de 5-flúor-1h-pirazolopiridinas substituídas | |
| BR112013018875A2 (pt) | métodos e composições para a preparação de noribogaína a partir de voacangina | |
| BR112014004622A8 (pt) | processo para a preparação de isocianatos | |
| CO6842021A2 (es) | Análogos de ácido epoxieicosatrienoico y métodos para elaborarlosy utilizarlos | |
| BR112014003352A2 (pt) | métodos para fabricação de construções estruturais | |
| BR112013023465A2 (pt) | método para produzir l-cisteína | |
| BR112013031365A2 (pt) | método para produzir um composto | |
| BR112014013694A2 (pt) | método para tratar uma doença, e, kit | |
| BR112013024413A2 (pt) | compostos e métodos para a preparação de diarilpropanos | |
| BR112013022548A2 (pt) | processo para a preparação de aminas primárias | |
| BR112014014052A2 (pt) | processo para a preparação de 5-hidroximetilfurfural | |
| BR112013031749A2 (pt) | Mecanismo de barramento e método de formar um mecanismo de barramento | |
| BR112014010327A2 (pt) | processo para a preparação de compostos | |
| BR112014015545A2 (pt) | processo de preparação de uma mistura | |
| BR112014008575A2 (pt) | processo para a preparação de ditina-tetracarboximidas | |
| BR112014007744A2 (pt) | processo para a preparação de uma mistura | |
| BR112014014564A2 (pt) | método para formar um produto baseado em gesso | |
| FI20115116A0 (fi) | Menetelmä uistimen valmistamiseksi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |