JP6378089B2 - 微生物におけるタンパク質産生のための、Ｂ．ズブチリス（Ｂ．ｓｕｂｔｉｌｉｓ）からのリボソームプロモーター - Google Patents

微生物におけるタンパク質産生のための、Ｂ．ズブチリス（Ｂ．ｓｕｂｔｉｌｉｓ）からのリボソームプロモーター Download PDF

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JP6378089B2
JP6378089B2 JP2014546087A JP2014546087A JP6378089B2 JP 6378089 B2 JP6378089 B2 JP 6378089B2 JP 2014546087 A JP2014546087 A JP 2014546087A JP 2014546087 A JP2014546087 A JP 2014546087A JP 6378089 B2 JP6378089 B2 JP 6378089B2
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nucleic acid
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JP2015500032A (ja
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ボンジョルニ、クリスティーナ
フォックス、ブライアン・ピー
ヴァン・キムネーデ・アニタ
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ダニスコ・ユーエス・インク
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

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  • Life Sciences & Earth Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
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  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
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  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2014546087A 2011-12-09 2012-12-06 微生物におけるタンパク質産生のための、Ｂ．ズブチリス（Ｂ．ｓｕｂｔｉｌｉｓ）からのリボソームプロモーター Active JP6378089B2 (ja)

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US201161569202P 2011-12-09 2011-12-09
US61/569,202 2011-12-09
US201161577491P 2011-12-19 2011-12-19
US61/577,491 2011-12-19
PCT/US2012/068285 WO2013086219A1 (en) 2011-12-09 2012-12-06 Ribosomal promotors from b. subtilis for protein production in microorganisms

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JP2015500032A JP2015500032A (ja) 2015-01-05
JP2015500032A5 JP2015500032A5 (https=) 2016-01-28
JP6378089B2 true JP6378089B2 (ja) 2018-08-22

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US (1) US20140329309A1 (https=)
EP (1) EP2788491B1 (https=)
JP (1) JP6378089B2 (https=)
CN (1) CN104053780A (https=)
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WO (1) WO2013086219A1 (https=)

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CN111944808B (zh) * 2019-05-16 2025-04-29 武汉合生科技有限公司 核糖体rna启动子在强启动表达非rna基因中的用途
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EP2788491B1 (en) 2019-01-23
JP2015500032A (ja) 2015-01-05
WO2013086219A1 (en) 2013-06-13
US20140329309A1 (en) 2014-11-06
EP2788491A1 (en) 2014-10-15
DK2788491T3 (en) 2019-04-01
CN104053780A (zh) 2014-09-17

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