DK2788491T3 - RIBOSOMAL PROMOTERS FROM B. SUBTILIS FOR PROTEIN PRODUCTION IN MICRO-ORGANISMS - Google Patents
RIBOSOMAL PROMOTERS FROM B. SUBTILIS FOR PROTEIN PRODUCTION IN MICRO-ORGANISMS Download PDFInfo
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- DK2788491T3 DK2788491T3 DK12806777.4T DK12806777T DK2788491T3 DK 2788491 T3 DK2788491 T3 DK 2788491T3 DK 12806777 T DK12806777 T DK 12806777T DK 2788491 T3 DK2788491 T3 DK 2788491T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
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- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
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| US201161569202P | 2011-12-09 | 2011-12-09 | |
| US201161577491P | 2011-12-19 | 2011-12-19 | |
| PCT/US2012/068285 WO2013086219A1 (en) | 2011-12-09 | 2012-12-06 | Ribosomal promotors from b. subtilis for protein production in microorganisms |
Publications (1)
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|---|---|
| DK2788491T3 true DK2788491T3 (en) | 2019-04-01 |
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| US (1) | US20140329309A1 (https=) |
| EP (1) | EP2788491B1 (https=) |
| JP (1) | JP6378089B2 (https=) |
| CN (1) | CN104053780A (https=) |
| DK (1) | DK2788491T3 (https=) |
| WO (1) | WO2013086219A1 (https=) |
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| EP3259358B1 (en) * | 2015-02-19 | 2024-06-19 | Danisco US Inc. | Enhanced protein expression |
| KR20180069057A (ko) | 2015-10-30 | 2018-06-22 | 다니스코 유에스 인크. | 향상된 단백질 발현 및 이의 방법 |
| MX391716B (es) * | 2015-12-14 | 2025-03-21 | Basf Se | Promotor de catalasa modificado bidireccional de bacilo. |
| US20180371445A1 (en) | 2015-12-23 | 2018-12-27 | Danisco Us Inc. | Enhanced protein production and methods thereof |
| WO2017152169A1 (en) | 2016-03-04 | 2017-09-08 | Danisco Us Inc. | Engineered ribosomal promoters for protein production in microorganisms |
| CA3027745A1 (en) | 2016-06-17 | 2017-12-21 | Danisco Us Inc. | Protease variants and uses thereof |
| EP4520820A3 (en) | 2016-12-21 | 2025-04-16 | Danisco Us Inc | Protease variants and uses thereof |
| MX2019007335A (es) | 2016-12-21 | 2019-09-09 | Dupont Nutrition Biosci Aps | Métodos para usar serina proteasas termoestables. |
| US11946081B2 (en) | 2016-12-21 | 2024-04-02 | Danisco Us Inc. | Bacillus gibsonii-clade serine proteases |
| EP3571217B1 (en) | 2017-01-23 | 2023-06-21 | Danisco US Inc. | Methods and compositions for obtaining natural competence in bacillus host cells |
| EP3585910B1 (en) | 2017-02-24 | 2024-03-20 | Danisco US Inc. | Compositions and methods for increased protein production in bacillus licheniformis |
| MX386582B (es) | 2017-03-15 | 2025-03-19 | Int N&H Denmark Aps | Métodos para usar una serina proteasa de arqueas. |
| EP3583210B1 (en) | 2017-03-15 | 2021-07-07 | Danisco US Inc. | Trypsin-like serine proteases and uses thereof |
| US20200015499A1 (en) | 2017-03-15 | 2020-01-16 | Dupont Nutrition Biosciences Aps | Trypsin-like serine proteases and uses thereof |
| WO2018187524A1 (en) | 2017-04-07 | 2018-10-11 | Dupont Nutrition Biosciences Aps | BACILLUS HOST CELLS PRODUCING β-GALACTOSIDASES AND LACTASES IN THE ABSENCE OF P-NITROBENZYLESTERASE SIDE ACTIVITY |
| WO2019055261A1 (en) | 2017-09-13 | 2019-03-21 | Danisco Us Inc | MODIFIED 5 'NON-TRANSLATED REGION (UTR) SEQUENCES FOR INCREASED PROTEIN PRODUCTION IN BACILLUS |
| EP3717643A1 (en) | 2017-11-29 | 2020-10-07 | Danisco US Inc. | Subtilisin variants having improved stability |
| JP7280269B2 (ja) | 2018-01-03 | 2023-05-23 | ダニスコ・ユーエス・インク | タンパク質の産生増加のための変異及び遺伝子改変バチルス属（ｂａｃｉｌｌｕｓ）細胞、並びにその方法 |
| CN110004166A (zh) * | 2018-01-05 | 2019-07-12 | 中国科学院天津工业生物技术研究所 | 高效表达分泌β-甘露聚糖酶的重组枯草芽孢杆菌菌株及其获得方法 |
| CN108441489B (zh) * | 2018-04-09 | 2023-04-14 | 潍坊康地恩生物科技有限公司 | 一种蛋白生产方法及高产碱性蛋白酶的枯草芽孢杆菌 |
| EP3799601A1 (en) | 2018-06-19 | 2021-04-07 | Danisco US Inc. | Subtilisin variants |
| WO2019245704A1 (en) | 2018-06-19 | 2019-12-26 | Danisco Us Inc | Subtilisin variants |
| BR112021000116A2 (pt) | 2018-07-06 | 2021-04-06 | Dupont Nutrition Biosciences Aps | Aditivos de alimento contendo xilanase para alimento de animal à base de cereal |
| CN113366108B (zh) * | 2018-11-28 | 2024-11-22 | 丹尼斯科美国公司 | 新颖启动子序列及其增强芽孢杆菌属细胞蛋白生产的方法 |
| US20220177923A1 (en) | 2019-04-05 | 2022-06-09 | Danisco Us Inc | Methods for integrating a donor DNA sequence into the genome of bacillus using linear recombinant DNA constructs and compositions thereof |
| CA3136113A1 (en) | 2019-04-05 | 2020-10-08 | Danisco Us Inc. | Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof |
| CN111944808B (zh) * | 2019-05-16 | 2025-04-29 | 武汉合生科技有限公司 | 核糖体rna启动子在强启动表达非rna基因中的用途 |
| CA3155372A1 (en) | 2019-10-28 | 2021-05-06 | Sharief Barends | Microbial host cells for the production of heterologous cyanuric acid hydrolases and biuret hydrolases |
| JP2023502967A (ja) | 2019-11-19 | 2023-01-26 | ダニスコ・ユーエス・インク | バチルス（Ｂａｃｉｌｌｕｓ）のゲノムを改変するための、選択マーカーを使用しない方法及びその組成物 |
| IL294248A (en) * | 2019-12-31 | 2022-08-01 | Air Protein Inc | High protein food compositions |
| CN114945665A (zh) | 2020-01-15 | 2022-08-26 | 丹尼斯科美国公司 | 用于增强地衣芽孢杆菌中蛋白产生的组合物和方法 |
| CN119630280A (zh) | 2022-05-14 | 2025-03-14 | 诺维信公司 | 用于预防、处理、抑制和/或消除植物病原性侵染和感染的组合物和方法 |
| KR20250054813A (ko) | 2022-09-02 | 2025-04-23 | 다니스코 유에스 인크. | 그람 양성 세포에서 단백질 생산을 향상시키는 신규한 프로모터 및 5'-비번역 영역 돌연변이 |
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| EP0351029B1 (en) | 1988-07-15 | 2002-03-06 | Genencor International, Inc. | Novel glucose isomerase enzymes and their use |
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| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| US6255115B1 (en) | 1997-04-07 | 2001-07-03 | Unilever Patent Holdings Bv | Agrobacterium mediated transformation of moulds, in particular those belonging to the genus Aspergillus |
| AR016969A1 (es) | 1997-10-23 | 2001-08-01 | Procter & Gamble | VARIANTE DE PROTEASA, ADN, VECTOR DE EXPRESIoN, MICROORGANISMO HUESPED, COMPOSICIoN DE LIMPIEZA, ALIMENTO PARA ANIMALES Y COMPOSICIoN PARA TRATAR UN TEXTIL |
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| FI108728B (fi) | 1999-10-12 | 2002-03-15 | Carbozyme Oy | Menetelmä perheen G/11 ksylanaasien stabiilisuuden parantamiseksi ja optimaalisen pH-alueen muuttamiseksi |
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| GB0422052D0 (en) | 2004-10-04 | 2004-11-03 | Dansico As | Enzymes |
| WO2006038128A2 (en) | 2004-10-04 | 2006-04-13 | Danisco A/S | Citrobacter freundii phytase and homologues |
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| AR074105A1 (es) | 2008-11-11 | 2010-12-22 | Danisco Us Inc | Composiciones y metodos que comprenden variantes de subtilisina |
| GB0922467D0 (en) | 2009-04-24 | 2010-02-03 | Danisco | Feed supplement |
| US8530218B2 (en) | 2009-04-24 | 2013-09-10 | Danisco Us Inc. | Proteases with modified pro regions |
| AR076941A1 (es) * | 2009-06-11 | 2011-07-20 | Danisco Us Inc | Cepa de bacillus para una mayor produccion de proteina |
| US20110171718A1 (en) | 2009-07-31 | 2011-07-14 | Danisco Us Inc. | Proteases With Modified Pre-Pro Regions |
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- 2012-12-06 WO PCT/US2012/068285 patent/WO2013086219A1/en not_active Ceased
- 2012-12-06 US US14/364,016 patent/US20140329309A1/en not_active Abandoned
- 2012-12-06 EP EP12806777.4A patent/EP2788491B1/en active Active
- 2012-12-06 JP JP2014546087A patent/JP6378089B2/ja active Active
- 2012-12-06 DK DK12806777.4T patent/DK2788491T3/en active
- 2012-12-06 CN CN201280059922.9A patent/CN104053780A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2788491B1 (en) | 2019-01-23 |
| JP2015500032A (ja) | 2015-01-05 |
| WO2013086219A1 (en) | 2013-06-13 |
| US20140329309A1 (en) | 2014-11-06 |
| EP2788491A1 (en) | 2014-10-15 |
| JP6378089B2 (ja) | 2018-08-22 |
| CN104053780A (zh) | 2014-09-17 |
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