JP6363948B2 - ＴＧＦ−βに特異的な抗体 - Google Patents

ＴＧＦ−βに特異的な抗体 Download PDF

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JP6363948B2
JP6363948B2 JP2014513760A JP2014513760A JP6363948B2 JP 6363948 B2 JP6363948 B2 JP 6363948B2 JP 2014513760 A JP2014513760 A JP 2014513760A JP 2014513760 A JP2014513760 A JP 2014513760A JP 6363948 B2 JP6363948 B2 JP 6363948B2
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antibody
fibrosis
seq
amino acid
light chain
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JP2014518064A (ja
JP2014518064A5 (enExample
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ダニエル ベディンジャー
ダニエル ベディンジャー
シリーン エス． カーン
シリーン エス． カーン
アメール ミルザ
アメール ミルザ
アジャイ ジェイ． ナラシンハ
アジャイ ジェイ． ナラシンハ
トシヒコ タケウチ
トシヒコ タケウチ
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ゾーマ テクノロジー リミテッド
ゾーマ テクノロジー リミテッド
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K—PEPTIDES
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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JP2014513760A 2011-06-03 2012-06-01 ＴＧＦ−βに特異的な抗体 Active JP6363948B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493230P 2011-06-03 2011-06-03
US61/493,230 2011-06-03
PCT/US2012/040545 WO2012167143A1 (en) 2011-06-03 2012-06-01 Antibodies specific for tgf-beta

Related Child Applications (1)

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JP2018123833A Division JP6571843B2 (ja) 2011-06-03 2018-06-29 ＴＧＦ−βに特異的な抗体

Publications (3)

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JP2014518064A JP2014518064A (ja) 2014-07-28
JP2014518064A5 JP2014518064A5 (enExample) 2015-07-23
JP6363948B2 true JP6363948B2 (ja) 2018-07-25

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JP2014513760A Active JP6363948B2 (ja) 2011-06-03 2012-06-01 ＴＧＦ−βに特異的な抗体
JP2018123833A Active JP6571843B2 (ja) 2011-06-03 2018-06-29 ＴＧＦ−βに特異的な抗体
JP2019146320A Active JP6877500B2 (ja) 2011-06-03 2019-08-08 ＴＧＦ−βに特異的な抗体
JP2021074575A Active JP7179903B2 (ja) 2011-06-03 2021-04-27 ＴＧＦ－βに特異的な抗体
JP2022183014A Pending JP2023015300A (ja) 2011-06-03 2022-11-16 ＴＧＦ－βに特異的な抗体

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JP2019146320A Active JP6877500B2 (ja) 2011-06-03 2019-08-08 ＴＧＦ−βに特異的な抗体
JP2021074575A Active JP7179903B2 (ja) 2011-06-03 2021-04-27 ＴＧＦ－βに特異的な抗体
JP2022183014A Pending JP2023015300A (ja) 2011-06-03 2022-11-16 ＴＧＦ－βに特異的な抗体

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US (6) US8569462B2 (enExample)
EP (2) EP3954704A1 (enExample)
JP (5) JP6363948B2 (enExample)
KR (4) KR102577578B1 (enExample)
CN (3) CN108424451B (enExample)
AU (4) AU2012261933B2 (enExample)
BR (1) BR112013030958B1 (enExample)
CA (1) CA2837556C (enExample)
CY (1) CY1124610T1 (enExample)
DK (1) DK2714735T3 (enExample)
EA (2) EA201990698A1 (enExample)
ES (1) ES2894398T3 (enExample)
HR (1) HRP20211582T1 (enExample)
HU (1) HUE056808T2 (enExample)
IL (2) IL229638B (enExample)
LT (1) LT2714735T (enExample)
MX (1) MX351600B (enExample)
MY (2) MY171135A (enExample)
PH (2) PH12013502489B1 (enExample)
PL (1) PL2714735T3 (enExample)
PT (1) PT2714735T (enExample)
RS (1) RS62457B1 (enExample)
SG (2) SG10201902706VA (enExample)
SI (1) SI2714735T1 (enExample)
WO (1) WO2012167143A1 (enExample)
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US9589417B2 (en) 2005-07-14 2017-03-07 Ag 18, Llc Interactive gaming among a plurality of players systems and methods
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
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