JP6309454B2 - 癌の併用処置 - Google Patents

癌の併用処置 Download PDF

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Publication number
JP6309454B2
JP6309454B2 JP2014543977A JP2014543977A JP6309454B2 JP 6309454 B2 JP6309454 B2 JP 6309454B2 JP 2014543977 A JP2014543977 A JP 2014543977A JP 2014543977 A JP2014543977 A JP 2014543977A JP 6309454 B2 JP6309454 B2 JP 6309454B2
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JP
Japan
Prior art keywords
combination
azd5363
pharmaceutically acceptable
acceptable salt
cancer
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JP2014543977A
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English (en)
Japanese (ja)
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JP2015500225A5 (enExample
JP2015500225A (ja
Inventor
デイヴィーズ，バリー・ロバート
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AstraZeneca AB
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AstraZeneca AB
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Publication of JP2015500225A publication Critical patent/JP2015500225A/ja
Publication of JP2015500225A5 publication Critical patent/JP2015500225A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2014543977A 2011-11-30 2012-11-30 癌の併用処置 Active JP6309454B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161564975P 2011-11-30 2011-11-30
US61/564,975 2011-11-30
PCT/GB2012/052969 WO2013079964A1 (en) 2011-11-30 2012-11-30 Combination treatment of cancer

Publications (3)

Publication Number Publication Date
JP2015500225A JP2015500225A (ja) 2015-01-05
JP2015500225A5 JP2015500225A5 (enExample) 2016-01-21
JP6309454B2 true JP6309454B2 (ja) 2018-04-11

Family

ID=47295082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014543977A Active JP6309454B2 (ja) 2011-11-30 2012-11-30 癌の併用処置

Country Status (26)

Country Link
US (2) US20140329786A1 (enExample)
EP (1) EP2785349B2 (enExample)
JP (1) JP6309454B2 (enExample)
KR (1) KR102035361B1 (enExample)
CN (1) CN103945849B (enExample)
AU (2) AU2012321110B2 (enExample)
CA (1) CA2856646C (enExample)
CY (1) CY1122624T1 (enExample)
DK (1) DK2785349T4 (enExample)
ES (1) ES2762250T5 (enExample)
FI (1) FI2785349T4 (enExample)
HR (1) HRP20191982T4 (enExample)
HU (1) HUE046667T2 (enExample)
IL (1) IL232530B (enExample)
LT (1) LT2785349T (enExample)
MX (1) MX367640B (enExample)
MY (1) MY175800A (enExample)
PH (1) PH12014500943A1 (enExample)
PL (1) PL2785349T5 (enExample)
PT (1) PT2785349T (enExample)
RS (1) RS59493B2 (enExample)
RU (1) RU2640485C2 (enExample)
SG (1) SG11201401471PA (enExample)
SI (1) SI2785349T2 (enExample)
SM (1) SMT201900708T1 (enExample)
WO (1) WO2013079964A1 (enExample)

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JP2020534320A (ja) * 2017-09-22 2020-11-26 ディスパーソル テクノロジーズ リミテッド ライアビリティ カンパニー アビラテロン環状オリゴマー薬学的製剤ならびにその形成法および投与法
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JP7644713B2 (ja) 2019-03-06 2025-03-12 プロペラ セラピューティクス インコーポレイテッド アビラテロンプロドラッグ

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Also Published As

Publication number Publication date
RU2014119713A (ru) 2016-01-27
US9737540B2 (en) 2017-08-22
CN103945849A (zh) 2014-07-23
MY175800A (en) 2020-07-09
WO2013079964A1 (en) 2013-06-06
IL232530B (en) 2018-07-31
PT2785349T (pt) 2019-12-11
SI2785349T2 (sl) 2023-01-31
MX2014006547A (es) 2014-07-09
CA2856646C (en) 2020-01-14
HK1202253A1 (en) 2015-09-25
RS59493B2 (sr) 2023-02-28
AU2012321110B2 (en) 2014-10-23
IL232530A0 (en) 2014-06-30
KR102035361B1 (ko) 2019-11-08
PL2785349T3 (pl) 2020-03-31
EP2785349A1 (en) 2014-10-08
DK2785349T4 (da) 2023-01-09
PL2785349T5 (pl) 2023-01-30
AU2013205648A1 (en) 2013-06-13
AU2013205648B2 (en) 2015-02-05
HUE046667T2 (hu) 2020-03-30
PH12014500943A1 (en) 2014-06-30
BR112014012261A2 (pt) 2017-06-13
AU2012321110A1 (en) 2013-06-20
CA2856646A1 (en) 2013-06-06
NZ625611A (en) 2016-10-28
HRP20191982T1 (hr) 2020-02-07
HRP20191982T4 (hr) 2023-01-06
EP2785349B1 (en) 2019-10-16
SMT201900708T1 (it) 2020-01-14
ES2762250T5 (es) 2023-01-05
RS59493B1 (sr) 2019-12-31
CN103945849B (zh) 2017-04-26
ES2762250T3 (es) 2020-05-22
CY1122624T1 (el) 2021-03-12
US20160151373A1 (en) 2016-06-02
US20140329786A1 (en) 2014-11-06
SG11201401471PA (en) 2014-08-28
MX367640B (es) 2019-08-29
JP2015500225A (ja) 2015-01-05
KR20140098799A (ko) 2014-08-08
DK2785349T3 (da) 2020-01-02
EP2785349B2 (en) 2022-11-09
LT2785349T (lt) 2019-12-10
RU2640485C2 (ru) 2018-01-09
FI2785349T4 (fi) 2023-02-09
SI2785349T1 (sl) 2019-12-31

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