JP6181646B2 - Ｔｎｆアルファによる生物学的治療に対する中和自己抗体の検出のためのアッセイ - Google Patents

Ｔｎｆアルファによる生物学的治療に対する中和自己抗体の検出のためのアッセイ Download PDF

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JP6181646B2
JP6181646B2 JP2014519077A JP2014519077A JP6181646B2 JP 6181646 B2 JP6181646 B2 JP 6181646B2 JP 2014519077 A JP2014519077 A JP 2014519077A JP 2014519077 A JP2014519077 A JP 2014519077A JP 6181646 B2 JP6181646 B2 JP 6181646B2
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tnfα
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JP2014525036A (ja
JP2014525036A5 (cg-RX-API-DMAC7.html
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スコット ハウエンスタイン，
スコット ハウエンスタイン，
リンダ オールムンド，
リンダ オールムンド，
シャラット シング，
シャラット シング，
シュイ ロン ワン，
シュイ ロン ワン，
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Nestec SA
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins

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  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Molecular Biology (AREA)
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  • Cell Biology (AREA)
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  • Pathology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014519077A 2011-07-06 2012-07-06 Ｔｎｆアルファによる生物学的治療に対する中和自己抗体の検出のためのアッセイ Expired - Fee Related JP6181646B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161505031P 2011-07-06 2011-07-06
US61/505,031 2011-07-06
US201161528072P 2011-08-26 2011-08-26
US61/528,072 2011-08-26
US201161535884P 2011-09-16 2011-09-16
US61/535,884 2011-09-16
PCT/US2012/045794 WO2013006810A1 (en) 2011-07-06 2012-07-06 Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha

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JP2014525036A JP2014525036A (ja) 2014-09-25
JP2014525036A5 JP2014525036A5 (cg-RX-API-DMAC7.html) 2015-08-27
JP6181646B2 true JP6181646B2 (ja) 2017-08-16

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US (2) US9465027B2 (cg-RX-API-DMAC7.html)
EP (2) EP3130921B1 (cg-RX-API-DMAC7.html)
JP (1) JP6181646B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140047628A (cg-RX-API-DMAC7.html)
CN (1) CN103782172A (cg-RX-API-DMAC7.html)
AU (2) AU2012278802B2 (cg-RX-API-DMAC7.html)
CA (1) CA2840232A1 (cg-RX-API-DMAC7.html)
MX (1) MX343324B (cg-RX-API-DMAC7.html)
RU (1) RU2013158256A (cg-RX-API-DMAC7.html)
SG (1) SG10201605516YA (cg-RX-API-DMAC7.html)
WO (1) WO2013006810A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201309703B (cg-RX-API-DMAC7.html)

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CN112730846B (zh) * 2020-12-18 2023-12-15 安渡生物医药(杭州)有限公司 一种用于小鼠血样检测免疫复合物的方法
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US9465027B2 (en) 2016-10-11
AU2016201196A1 (en) 2016-03-17
EP3130921A1 (en) 2017-02-15
JP2014525036A (ja) 2014-09-25
AU2012278802A1 (en) 2013-05-02
SG10201605516YA (en) 2016-08-30
AU2012278802B2 (en) 2015-11-26
HK1194467A1 (zh) 2014-10-17
EP3130921B1 (en) 2018-09-12
EP2729807A1 (en) 2014-05-14
AU2016201196B2 (en) 2018-01-25
MX343324B (es) 2016-11-01
KR20140047628A (ko) 2014-04-22
CN103782172A (zh) 2014-05-07
NZ619172A (en) 2016-01-29
EP2729807B1 (en) 2016-08-17
US20170176433A1 (en) 2017-06-22
US10794906B2 (en) 2020-10-06
US20140186973A1 (en) 2014-07-03
WO2013006810A1 (en) 2013-01-10
RU2013158256A (ru) 2015-07-10
CA2840232A1 (en) 2013-01-10
ZA201309703B (en) 2019-09-25

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