JP6170234B2 - レベチラセタムを含む急速に分散する剤形 - Google Patents

レベチラセタムを含む急速に分散する剤形 Download PDF

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Publication number
JP6170234B2
JP6170234B2 JP2016502945A JP2016502945A JP6170234B2 JP 6170234 B2 JP6170234 B2 JP 6170234B2 JP 2016502945 A JP2016502945 A JP 2016502945A JP 2016502945 A JP2016502945 A JP 2016502945A JP 6170234 B2 JP6170234 B2 JP 6170234B2
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dosage form
matrix
lev
less
bound
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JP2016514680A (ja
JP2016514680A5 (cg-RX-API-DMAC7.html
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ジュール・ジェイコブ
ノーマン・コイル
トーマス・ジー・ウェスト
ドナルド・シー・モンクハウス
ヘンリー・エル・サープリナント
ネミチャンド・ビー・ジェイン
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アプレシア・ファーマスーティカルズ・カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016502945A 2013-03-15 2014-03-14 レベチラセタムを含む急速に分散する剤形 Active JP6170234B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791444P 2013-03-15 2013-03-15
US61/791,444 2013-03-15
PCT/US2014/028954 WO2014144512A1 (en) 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam

Related Child Applications (1)

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JP2016231964A Division JP6640069B2 (ja) 2013-03-15 2016-11-30 レベチラセタムを含む急速に分散する剤形

Publications (3)

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JP2016514680A JP2016514680A (ja) 2016-05-23
JP2016514680A5 JP2016514680A5 (cg-RX-API-DMAC7.html) 2016-09-15
JP6170234B2 true JP6170234B2 (ja) 2017-07-26

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JP2016502945A Active JP6170234B2 (ja) 2013-03-15 2014-03-14 レベチラセタムを含む急速に分散する剤形
JP2016231964A Active JP6640069B2 (ja) 2013-03-15 2016-11-30 レベチラセタムを含む急速に分散する剤形
JP2018116552A Active JP6788633B2 (ja) 2013-03-15 2018-06-20 レベチラセタムを含む急速に分散する剤形

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JP2018116552A Active JP6788633B2 (ja) 2013-03-15 2018-06-20 レベチラセタムを含む急速に分散する剤形

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Country Link
US (2) US20220211668A1 (cg-RX-API-DMAC7.html)
EP (2) EP2968994B1 (cg-RX-API-DMAC7.html)
JP (3) JP6170234B2 (cg-RX-API-DMAC7.html)
CN (2) CN105188849B (cg-RX-API-DMAC7.html)
AU (2) AU2014228990B2 (cg-RX-API-DMAC7.html)
CA (1) CA2906029C (cg-RX-API-DMAC7.html)
ES (2) ES2908292T3 (cg-RX-API-DMAC7.html)
HK (1) HK1216513A1 (cg-RX-API-DMAC7.html)
MX (1) MX365513B (cg-RX-API-DMAC7.html)
WO (1) WO2014144512A1 (cg-RX-API-DMAC7.html)

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AU2014228990B2 (en) 2013-03-15 2017-02-02 Aprecia Pharmaceuticals LLC Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof
KR20180014778A (ko) 2015-06-03 2018-02-09 트리아스텍 인코포레이티드 제형 및 이의 용도
JP7023935B2 (ja) 2016-09-09 2022-02-22 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 固形医薬品投与形態の製造のためのプロセス
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WO2018156141A1 (en) 2017-02-24 2018-08-30 Hewlett-Packard Development Company, L.P. Three-dimensional (3d) printing a pharmaceutical tablet
CN110381925A (zh) 2017-03-08 2019-10-25 辛瑞克斯制药有限公司 间苯三酚和三甲基间苯三酚的药物制剂
JP6970183B2 (ja) 2017-03-31 2021-11-24 日本製鉄株式会社 固体高分子形燃料電池の触媒担体用炭素材料及びその製造方法
WO2018230329A1 (ja) * 2017-06-16 2018-12-20 丸石製薬株式会社 レベチラセタム含有ゲル経口医薬組成物
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
JP7264711B2 (ja) * 2019-04-26 2023-04-25 東和薬品株式会社 レベチラセタム含有医薬組成物の製造方法
BR112021024026A2 (pt) 2019-05-31 2022-02-08 Dihesys Digital Health Systems Gmbh Método para a produção de uma forma de dosagem farmacêutica sólida ou semissólida, forma de dosagem farmacêutica sólida ou semissólida e forma de dosagem sólida ou semissólida
TWI734309B (zh) * 2019-12-19 2021-07-21 水星生醫股份有限公司 滲透性噴塗製作藥錠裝置
CN111840243B (zh) * 2020-07-30 2021-11-30 中国人民解放军军事科学院军事医学研究院 一种左乙拉西坦3d打印制剂及其制备方法
CN113599362A (zh) * 2021-01-15 2021-11-05 中国人民解放军军事科学院军事医学研究院 一种3d打印制剂及其制备方法和其应用

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