JP6077554B2 - 薬用花を活用した包み発酵法およびこれを活用した皮膚外用剤組成物 - Google Patents
薬用花を活用した包み発酵法およびこれを活用した皮膚外用剤組成物 Download PDFInfo
- Publication number
- JP6077554B2 JP6077554B2 JP2014538700A JP2014538700A JP6077554B2 JP 6077554 B2 JP6077554 B2 JP 6077554B2 JP 2014538700 A JP2014538700 A JP 2014538700A JP 2014538700 A JP2014538700 A JP 2014538700A JP 6077554 B2 JP6077554 B2 JP 6077554B2
- Authority
- JP
- Japan
- Prior art keywords
- skin
- flowers
- medicinal
- action
- flower
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title claims description 27
- 238000002360 preparation method Methods 0.000 title claims description 18
- 238000000034 method Methods 0.000 title claims description 17
- 238000000855 fermentation Methods 0.000 title description 13
- 230000004151 fermentation Effects 0.000 title description 13
- 239000000284 extract Substances 0.000 claims description 57
- 229930014626 natural product Natural products 0.000 claims description 42
- 241001107116 Castanospermum australe Species 0.000 claims description 41
- 235000021279 black bean Nutrition 0.000 claims description 41
- 240000002853 Nelumbo nucifera Species 0.000 claims description 39
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 39
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 38
- 244000025254 Cannabis sativa Species 0.000 claims description 31
- 238000004519 manufacturing process Methods 0.000 claims description 22
- 230000003078 antioxidant effect Effects 0.000 claims description 20
- 239000003963 antioxidant agent Substances 0.000 claims description 14
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 13
- 235000008708 Morus alba Nutrition 0.000 claims description 12
- 240000000249 Morus alba Species 0.000 claims description 12
- 230000003712 anti-aging effect Effects 0.000 claims description 11
- 241000283690 Bos taurus Species 0.000 claims description 10
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims description 9
- 230000003020 moisturizing effect Effects 0.000 claims description 9
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 claims description 8
- 244000178937 Brassica oleracea var. capitata Species 0.000 claims description 8
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 8
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 8
- 229910052737 gold Inorganic materials 0.000 claims description 8
- 239000010931 gold Substances 0.000 claims description 8
- 229910052709 silver Inorganic materials 0.000 claims description 8
- 239000004332 silver Substances 0.000 claims description 8
- 235000002789 Panax ginseng Nutrition 0.000 claims description 7
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 7
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 7
- 230000009286 beneficial effect Effects 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 7
- 240000005378 Magnolia kobus Species 0.000 claims description 6
- 235000014196 Magnolia kobus Nutrition 0.000 claims description 6
- 244000000626 Daucus carota Species 0.000 claims description 5
- 235000002767 Daucus carota Nutrition 0.000 claims description 5
- 240000001008 Dimocarpus longan Species 0.000 claims description 5
- 235000000235 Euphoria longan Nutrition 0.000 claims description 5
- 241000219925 Oenothera Species 0.000 claims description 5
- 235000004496 Oenothera biennis Nutrition 0.000 claims description 5
- 240000004922 Vigna radiata Species 0.000 claims description 5
- 235000010721 Vigna radiata var radiata Nutrition 0.000 claims description 5
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 claims description 5
- 240000005250 Chrysanthemum indicum Species 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 4
- 235000013555 soy sauce Nutrition 0.000 claims description 4
- 241000269851 Sarda sarda Species 0.000 claims description 2
- 206010040829 Skin discolouration Diseases 0.000 claims 1
- 230000009471 action Effects 0.000 description 77
- 239000003814 drug Substances 0.000 description 70
- 210000003491 skin Anatomy 0.000 description 67
- 230000000144 pharmacologic effect Effects 0.000 description 59
- 241000196324 Embryophyta Species 0.000 description 52
- 230000000694 effects Effects 0.000 description 44
- 206010037660 Pyrexia Diseases 0.000 description 43
- 206010011224 Cough Diseases 0.000 description 35
- 241000380130 Ehrharta erecta Species 0.000 description 32
- 206010042674 Swelling Diseases 0.000 description 32
- 230000000052 comparative effect Effects 0.000 description 32
- 230000008961 swelling Effects 0.000 description 32
- 235000013399 edible fruits Nutrition 0.000 description 31
- 230000001882 diuretic effect Effects 0.000 description 29
- 230000036407 pain Effects 0.000 description 29
- 208000002193 Pain Diseases 0.000 description 28
- 210000004369 blood Anatomy 0.000 description 28
- 239000008280 blood Substances 0.000 description 28
- 208000024891 symptom Diseases 0.000 description 28
- 206010047700 Vomiting Diseases 0.000 description 27
- 230000001754 anti-pyretic effect Effects 0.000 description 27
- 230000008673 vomiting Effects 0.000 description 27
- 239000002221 antipyretic Substances 0.000 description 26
- 239000000463 material Substances 0.000 description 26
- 206010019233 Headaches Diseases 0.000 description 25
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 25
- 231100000869 headache Toxicity 0.000 description 25
- 238000012360 testing method Methods 0.000 description 25
- 206010012735 Diarrhoea Diseases 0.000 description 24
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 23
- 230000001256 tonic effect Effects 0.000 description 23
- 230000036772 blood pressure Effects 0.000 description 22
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 21
- 230000000844 anti-bacterial effect Effects 0.000 description 21
- 206010030113 Oedema Diseases 0.000 description 20
- 201000010099 disease Diseases 0.000 description 20
- 210000002784 stomach Anatomy 0.000 description 20
- 230000003110 anti-inflammatory effect Effects 0.000 description 19
- 208000006673 asthma Diseases 0.000 description 19
- 235000009508 confectionery Nutrition 0.000 description 19
- 230000001629 suppression Effects 0.000 description 19
- 208000004998 Abdominal Pain Diseases 0.000 description 18
- 206010023126 Jaundice Diseases 0.000 description 18
- 239000002934 diuretic Substances 0.000 description 18
- 239000000126 substance Substances 0.000 description 18
- 208000000616 Hemoptysis Diseases 0.000 description 17
- 229940069765 bean extract Drugs 0.000 description 17
- 230000000954 anitussive effect Effects 0.000 description 16
- 210000004027 cell Anatomy 0.000 description 16
- 206010033799 Paralysis Diseases 0.000 description 15
- 208000001848 dysentery Diseases 0.000 description 15
- 208000001780 epistaxis Diseases 0.000 description 15
- 230000001965 increasing effect Effects 0.000 description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
- 102000029816 Collagenase Human genes 0.000 description 14
- 108060005980 Collagenase Proteins 0.000 description 14
- 208000032843 Hemorrhage Diseases 0.000 description 14
- 206010068319 Oropharyngeal pain Diseases 0.000 description 14
- 208000004880 Polyuria Diseases 0.000 description 14
- 206010036790 Productive cough Diseases 0.000 description 14
- 229960002424 collagenase Drugs 0.000 description 14
- 230000003419 expectorant effect Effects 0.000 description 14
- 208000014617 hemorrhoid Diseases 0.000 description 14
- 230000007794 irritation Effects 0.000 description 14
- 239000002609 medium Substances 0.000 description 14
- 230000028327 secretion Effects 0.000 description 14
- 206010010774 Constipation Diseases 0.000 description 13
- 206010020772 Hypertension Diseases 0.000 description 13
- 201000007100 Pharyngitis Diseases 0.000 description 13
- 206010046788 Uterine haemorrhage Diseases 0.000 description 13
- 235000006708 antioxidants Nutrition 0.000 description 13
- 229940124584 antitussives Drugs 0.000 description 13
- 231100000319 bleeding Toxicity 0.000 description 13
- 230000000740 bleeding effect Effects 0.000 description 13
- 239000003172 expectorant agent Substances 0.000 description 13
- 230000023597 hemostasis Effects 0.000 description 13
- 230000002401 inhibitory effect Effects 0.000 description 13
- 210000002700 urine Anatomy 0.000 description 13
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 12
- 108010050808 Procollagen Proteins 0.000 description 12
- 208000034158 bleeding Diseases 0.000 description 12
- 210000003414 extremity Anatomy 0.000 description 12
- 210000003734 kidney Anatomy 0.000 description 12
- 208000008035 Back Pain Diseases 0.000 description 11
- 208000034656 Contusions Diseases 0.000 description 11
- 201000004624 Dermatitis Diseases 0.000 description 11
- 241000207923 Lamiaceae Species 0.000 description 11
- 238000002835 absorbance Methods 0.000 description 11
- 230000036592 analgesia Effects 0.000 description 11
- 230000000202 analgesic effect Effects 0.000 description 11
- 206010006451 bronchitis Diseases 0.000 description 11
- 235000012000 cholesterol Nutrition 0.000 description 11
- 208000006454 hepatitis Diseases 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 11
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 10
- 241000208838 Asteraceae Species 0.000 description 10
- 206010039897 Sedation Diseases 0.000 description 10
- 230000017531 blood circulation Effects 0.000 description 10
- 230000007423 decrease Effects 0.000 description 10
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 description 10
- 230000035619 diuresis Effects 0.000 description 10
- 239000000706 filtrate Substances 0.000 description 10
- 210000004185 liver Anatomy 0.000 description 10
- 210000003205 muscle Anatomy 0.000 description 10
- 230000002265 prevention Effects 0.000 description 10
- 210000000952 spleen Anatomy 0.000 description 10
- 210000003802 sputum Anatomy 0.000 description 10
- 208000024794 sputum Diseases 0.000 description 10
- 235000019640 taste Nutrition 0.000 description 10
- 206010000060 Abdominal distension Diseases 0.000 description 9
- 230000032683 aging Effects 0.000 description 9
- 206010003246 arthritis Diseases 0.000 description 9
- 239000003795 chemical substances by application Substances 0.000 description 9
- 238000001035 drying Methods 0.000 description 9
- 235000013372 meat Nutrition 0.000 description 9
- 230000002829 reductive effect Effects 0.000 description 9
- 230000036280 sedation Effects 0.000 description 9
- 230000002087 whitening effect Effects 0.000 description 9
- 240000000530 Alcea rosea Species 0.000 description 8
- 235000017334 Alcea rosea Nutrition 0.000 description 8
- 235000017303 Althaea rosea Nutrition 0.000 description 8
- 208000010201 Exanthema Diseases 0.000 description 8
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 8
- 210000001015 abdomen Anatomy 0.000 description 8
- 201000011510 cancer Diseases 0.000 description 8
- 210000000038 chest Anatomy 0.000 description 8
- 201000006549 dyspepsia Diseases 0.000 description 8
- 201000005884 exanthem Diseases 0.000 description 8
- 210000002216 heart Anatomy 0.000 description 8
- 230000002439 hemostatic effect Effects 0.000 description 8
- -1 lipid peroxides Chemical class 0.000 description 8
- 206010037844 rash Diseases 0.000 description 8
- 235000000346 sugar Nutrition 0.000 description 8
- 230000002485 urinary effect Effects 0.000 description 8
- 108010035532 Collagen Proteins 0.000 description 7
- 102000008186 Collagen Human genes 0.000 description 7
- 235000011511 Diospyros Nutrition 0.000 description 7
- 208000005171 Dysmenorrhea Diseases 0.000 description 7
- 206010061218 Inflammation Diseases 0.000 description 7
- 208000008930 Low Back Pain Diseases 0.000 description 7
- 206010028980 Neoplasm Diseases 0.000 description 7
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 7
- 235000011613 Pinus brutia Nutrition 0.000 description 7
- 241000018646 Pinus brutia Species 0.000 description 7
- 208000004210 Pressure Ulcer Diseases 0.000 description 7
- 244000269722 Thea sinensis Species 0.000 description 7
- 208000010668 atopic eczema Diseases 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 7
- 210000000988 bone and bone Anatomy 0.000 description 7
- 229920001436 collagen Polymers 0.000 description 7
- 229940079593 drug Drugs 0.000 description 7
- 230000003908 liver function Effects 0.000 description 7
- 230000027939 micturition Effects 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 235000019198 oils Nutrition 0.000 description 7
- 230000001624 sedative effect Effects 0.000 description 7
- 239000013589 supplement Substances 0.000 description 7
- 235000019154 vitamin C Nutrition 0.000 description 7
- 239000011718 vitamin C Substances 0.000 description 7
- 230000037303 wrinkles Effects 0.000 description 7
- 206010063409 Acarodermatitis Diseases 0.000 description 6
- 206010003210 Arteriosclerosis Diseases 0.000 description 6
- 206010003445 Ascites Diseases 0.000 description 6
- 241000282994 Cervidae Species 0.000 description 6
- 206010009866 Cold sweat Diseases 0.000 description 6
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 6
- 244000068988 Glycine max Species 0.000 description 6
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 6
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 6
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 6
- 208000008454 Hyperhidrosis Diseases 0.000 description 6
- 241000233855 Orchidaceae Species 0.000 description 6
- 241000447727 Scabies Species 0.000 description 6
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 6
- 229930003268 Vitamin C Natural products 0.000 description 6
- 244000273928 Zingiber officinale Species 0.000 description 6
- 235000006886 Zingiber officinale Nutrition 0.000 description 6
- 208000002894 beriberi Diseases 0.000 description 6
- 238000009835 boiling Methods 0.000 description 6
- 230000000747 cardiac effect Effects 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 6
- 206010012601 diabetes mellitus Diseases 0.000 description 6
- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 description 6
- 206010013781 dry mouth Diseases 0.000 description 6
- 230000012953 feeding on blood of other organism Effects 0.000 description 6
- 235000008397 ginger Nutrition 0.000 description 6
- 231100000283 hepatitis Toxicity 0.000 description 6
- 230000000968 intestinal effect Effects 0.000 description 6
- 210000003127 knee Anatomy 0.000 description 6
- 229940010454 licorice Drugs 0.000 description 6
- 201000004792 malaria Diseases 0.000 description 6
- 229940126601 medicinal product Drugs 0.000 description 6
- 230000008099 melanin synthesis Effects 0.000 description 6
- 208000004296 neuralgia Diseases 0.000 description 6
- 231100000614 poison Toxicity 0.000 description 6
- 239000002574 poison Substances 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 208000005687 scabies Diseases 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 230000035900 sweating Effects 0.000 description 6
- 235000013616 tea Nutrition 0.000 description 6
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 5
- 244000144730 Amygdalus persica Species 0.000 description 5
- 206010003011 Appendicitis Diseases 0.000 description 5
- 208000006820 Arthralgia Diseases 0.000 description 5
- 206010006458 Bronchitis chronic Diseases 0.000 description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 5
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 5
- 244000020518 Carthamus tinctorius Species 0.000 description 5
- 241000207199 Citrus Species 0.000 description 5
- 240000004270 Colocasia esculenta var. antiquorum Species 0.000 description 5
- 206010011985 Decubitus ulcer Diseases 0.000 description 5
- 244000236655 Diospyros kaki Species 0.000 description 5
- 235000010469 Glycine max Nutrition 0.000 description 5
- 240000004670 Glycyrrhiza echinata Species 0.000 description 5
- 206010028813 Nausea Diseases 0.000 description 5
- 235000004789 Rosa xanthina Nutrition 0.000 description 5
- 235000002597 Solanum melongena Nutrition 0.000 description 5
- 244000061458 Solanum melongena Species 0.000 description 5
- 208000007107 Stomach Ulcer Diseases 0.000 description 5
- 206010046914 Vaginal infection Diseases 0.000 description 5
- 201000008100 Vaginitis Diseases 0.000 description 5
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 5
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 5
- 230000001093 anti-cancer Effects 0.000 description 5
- 230000000259 anti-tumor effect Effects 0.000 description 5
- 239000007864 aqueous solution Substances 0.000 description 5
- 210000000941 bile Anatomy 0.000 description 5
- 239000011575 calcium Substances 0.000 description 5
- 229910052791 calcium Inorganic materials 0.000 description 5
- 238000005119 centrifugation Methods 0.000 description 5
- 208000007451 chronic bronchitis Diseases 0.000 description 5
- 235000020971 citrus fruits Nutrition 0.000 description 5
- 201000003146 cystitis Diseases 0.000 description 5
- 230000029087 digestion Effects 0.000 description 5
- 239000004744 fabric Substances 0.000 description 5
- 238000001914 filtration Methods 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 201000005917 gastric ulcer Diseases 0.000 description 5
- 210000004209 hair Anatomy 0.000 description 5
- 230000009931 harmful effect Effects 0.000 description 5
- 241000411851 herbal medicine Species 0.000 description 5
- 208000021760 high fever Diseases 0.000 description 5
- 230000004054 inflammatory process Effects 0.000 description 5
- 210000000936 intestine Anatomy 0.000 description 5
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 5
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 5
- 229960004705 kojic acid Drugs 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 230000008693 nausea Effects 0.000 description 5
- 239000013641 positive control Substances 0.000 description 5
- 238000010992 reflux Methods 0.000 description 5
- 230000000241 respiratory effect Effects 0.000 description 5
- 239000000932 sedative agent Substances 0.000 description 5
- 210000004243 sweat Anatomy 0.000 description 5
- 235000019155 vitamin A Nutrition 0.000 description 5
- 239000011719 vitamin A Substances 0.000 description 5
- 229940045997 vitamin a Drugs 0.000 description 5
- 206010065360 Anal prolapse Diseases 0.000 description 4
- 208000019901 Anxiety disease Diseases 0.000 description 4
- 241000972773 Aulopiformes Species 0.000 description 4
- 235000009113 Betula papyrifera Nutrition 0.000 description 4
- 235000009109 Betula pendula Nutrition 0.000 description 4
- 244000089654 Betula populifolia Species 0.000 description 4
- 235000010928 Betula populifolia Nutrition 0.000 description 4
- 235000002992 Betula pubescens Nutrition 0.000 description 4
- 241000123667 Campanula Species 0.000 description 4
- 235000013162 Cocos nucifera Nutrition 0.000 description 4
- 244000060011 Cocos nucifera Species 0.000 description 4
- 241000254173 Coleoptera Species 0.000 description 4
- 240000008067 Cucumis sativus Species 0.000 description 4
- 208000007882 Gastritis Diseases 0.000 description 4
- 241000238631 Hexapoda Species 0.000 description 4
- 206010020565 Hyperaemia Diseases 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 4
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 4
- 240000004371 Panax ginseng Species 0.000 description 4
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 4
- 235000003140 Panax quinquefolius Nutrition 0.000 description 4
- 235000006040 Prunus persica var persica Nutrition 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 4
- 201000004681 Psoriasis Diseases 0.000 description 4
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 4
- 241000220222 Rosaceae Species 0.000 description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 4
- 208000009205 Tinnitus Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 230000003187 abdominal effect Effects 0.000 description 4
- 229930013930 alkaloid Natural products 0.000 description 4
- 208000007502 anemia Diseases 0.000 description 4
- 230000001773 anti-convulsant effect Effects 0.000 description 4
- 230000002921 anti-spasmodic effect Effects 0.000 description 4
- 239000003434 antitussive agent Substances 0.000 description 4
- 230000036506 anxiety Effects 0.000 description 4
- 208000011775 arteriosclerosis disease Diseases 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000023555 blood coagulation Effects 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 4
- 208000002173 dizziness Diseases 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000004438 eyesight Effects 0.000 description 4
- 239000003925 fat Substances 0.000 description 4
- 235000019197 fats Nutrition 0.000 description 4
- 235000019688 fish Nutrition 0.000 description 4
- 230000002496 gastric effect Effects 0.000 description 4
- 235000008434 ginseng Nutrition 0.000 description 4
- 230000036737 immune function Effects 0.000 description 4
- 206010022437 insomnia Diseases 0.000 description 4
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 4
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 4
- 210000002510 keratinocyte Anatomy 0.000 description 4
- 230000003907 kidney function Effects 0.000 description 4
- 239000004922 lacquer Substances 0.000 description 4
- 235000021374 legumes Nutrition 0.000 description 4
- 201000003453 lung abscess Diseases 0.000 description 4
- 206010025482 malaise Diseases 0.000 description 4
- 206010027175 memory impairment Diseases 0.000 description 4
- 208000011309 nasal bleeding Diseases 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 239000002953 phosphate buffered saline Substances 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 235000019515 salmon Nutrition 0.000 description 4
- 239000002689 soil Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 238000010025 steaming Methods 0.000 description 4
- 231100000886 tinnitus Toxicity 0.000 description 4
- 239000011732 tocopherol Substances 0.000 description 4
- 229960001295 tocopherol Drugs 0.000 description 4
- 229930003799 tocopherol Natural products 0.000 description 4
- 235000010384 tocopherol Nutrition 0.000 description 4
- 231100000331 toxic Toxicity 0.000 description 4
- 230000002588 toxic effect Effects 0.000 description 4
- 210000004291 uterus Anatomy 0.000 description 4
- 235000013311 vegetables Nutrition 0.000 description 4
- 229940088594 vitamin Drugs 0.000 description 4
- 229930003231 vitamin Natural products 0.000 description 4
- 235000013343 vitamin Nutrition 0.000 description 4
- 239000011782 vitamin Substances 0.000 description 4
- 239000000341 volatile oil Substances 0.000 description 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 4
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 description 3
- 206010001497 Agitation Diseases 0.000 description 3
- 201000000736 Amenorrhea Diseases 0.000 description 3
- 206010001928 Amenorrhoea Diseases 0.000 description 3
- 240000007087 Apium graveolens Species 0.000 description 3
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 3
- 235000010591 Appio Nutrition 0.000 description 3
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 3
- 235000018185 Betula X alpestris Nutrition 0.000 description 3
- 235000018212 Betula X uliginosa Nutrition 0.000 description 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
- 240000002791 Brassica napus Species 0.000 description 3
- 235000010149 Brassica rapa subsp chinensis Nutrition 0.000 description 3
- 235000000536 Brassica rapa subsp pekinensis Nutrition 0.000 description 3
- 241000499436 Brassica rapa subsp. pekinensis Species 0.000 description 3
- 241000208250 Calotropis gigantea Species 0.000 description 3
- 240000001548 Camellia japonica Species 0.000 description 3
- 206010010305 Confusional state Diseases 0.000 description 3
- 241000190633 Cordyceps Species 0.000 description 3
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 3
- 241000219104 Cucurbitaceae Species 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- 208000008967 Enuresis Diseases 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- 235000014066 European mistletoe Nutrition 0.000 description 3
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 description 3
- 241000287828 Gallus gallus Species 0.000 description 3
- 241000222336 Ganoderma Species 0.000 description 3
- 206010018612 Gonorrhoea Diseases 0.000 description 3
- 201000005569 Gout Diseases 0.000 description 3
- 235000003222 Helianthus annuus Nutrition 0.000 description 3
- 244000020551 Helianthus annuus Species 0.000 description 3
- 241000234280 Liliaceae Species 0.000 description 3
- 208000037093 Menstruation Disturbances Diseases 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 208000007101 Muscle Cramp Diseases 0.000 description 3
- 208000000112 Myalgia Diseases 0.000 description 3
- 206010028735 Nasal congestion Diseases 0.000 description 3
- 241000207834 Oleaceae Species 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- 206010035664 Pneumonia Diseases 0.000 description 3
- 241000209504 Poaceae Species 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 244000184734 Pyrus japonica Species 0.000 description 3
- 241000219492 Quercus Species 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 240000000513 Santalum album Species 0.000 description 3
- 235000008632 Santalum album Nutrition 0.000 description 3
- 235000003434 Sesamum indicum Nutrition 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 244000019194 Sorbus aucuparia Species 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 208000033809 Suppuration Diseases 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 3
- 231100000354 acute hepatitis Toxicity 0.000 description 3
- 231100000540 amenorrhea Toxicity 0.000 description 3
- 239000001961 anticonvulsive agent Substances 0.000 description 3
- 229960003965 antiepileptics Drugs 0.000 description 3
- 229940030225 antihemorrhagics Drugs 0.000 description 3
- 210000003056 antler Anatomy 0.000 description 3
- 235000019658 bitter taste Nutrition 0.000 description 3
- 208000027503 bloody stool Diseases 0.000 description 3
- 230000003177 cardiotonic effect Effects 0.000 description 3
- 238000004113 cell culture Methods 0.000 description 3
- 239000000812 cholinergic antagonist Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 235000018597 common camellia Nutrition 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 230000004069 differentiation Effects 0.000 description 3
- 230000001079 digestive effect Effects 0.000 description 3
- 229940030606 diuretics Drugs 0.000 description 3
- 206010013990 dysuria Diseases 0.000 description 3
- 229910052571 earthenware Inorganic materials 0.000 description 3
- 229940088598 enzyme Drugs 0.000 description 3
- 230000002964 excitative effect Effects 0.000 description 3
- 239000010685 fatty oil Substances 0.000 description 3
- 239000012091 fetal bovine serum Substances 0.000 description 3
- 230000010030 glucose lowering effect Effects 0.000 description 3
- 208000001786 gonorrhea Diseases 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 230000009036 growth inhibition Effects 0.000 description 3
- 208000035861 hematochezia Diseases 0.000 description 3
- 239000002874 hemostatic agent Substances 0.000 description 3
- 230000002440 hepatic effect Effects 0.000 description 3
- 230000002218 hypoglycaemic effect Effects 0.000 description 3
- 201000001881 impotence Diseases 0.000 description 3
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 230000000749 insecticidal effect Effects 0.000 description 3
- 230000001788 irregular Effects 0.000 description 3
- 208000024765 knee pain Diseases 0.000 description 3
- 201000003265 lymphadenitis Diseases 0.000 description 3
- 210000001809 melena Anatomy 0.000 description 3
- 231100000544 menstrual irregularity Toxicity 0.000 description 3
- 208000013465 muscle pain Diseases 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 201000008383 nephritis Diseases 0.000 description 3
- 210000001331 nose Anatomy 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 230000035935 pregnancy Effects 0.000 description 3
- 206010036596 premature ejaculation Diseases 0.000 description 3
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 description 3
- 206010039083 rhinitis Diseases 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 229930182490 saponin Natural products 0.000 description 3
- 150000007949 saponins Chemical class 0.000 description 3
- 235000017709 saponins Nutrition 0.000 description 3
- 210000000582 semen Anatomy 0.000 description 3
- 230000035807 sensation Effects 0.000 description 3
- 235000019615 sensations Nutrition 0.000 description 3
- 235000006414 serbal de cazadores Nutrition 0.000 description 3
- 238000004904 shortening Methods 0.000 description 3
- 208000017520 skin disease Diseases 0.000 description 3
- 210000002460 smooth muscle Anatomy 0.000 description 3
- 230000003393 splenic effect Effects 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- 235000018553 tannin Nutrition 0.000 description 3
- 239000001648 tannin Substances 0.000 description 3
- 229920001864 tannin Polymers 0.000 description 3
- 208000004371 toothache Diseases 0.000 description 3
- 208000000143 urethritis Diseases 0.000 description 3
- 210000003932 urinary bladder Anatomy 0.000 description 3
- 150000003722 vitamin derivatives Chemical class 0.000 description 3
- 239000009538 yokuinin Substances 0.000 description 3
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 2
- DANYIYRPLHHOCZ-UHFFFAOYSA-N 5,7-dihydroxy-4'-methoxyflavone Chemical compound C1=CC(OC)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 DANYIYRPLHHOCZ-UHFFFAOYSA-N 0.000 description 2
- HGUVPEBGCAVWID-KETMJRJWSA-N 7-O-(beta-D-glucosyl)isovitexin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1O)[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=CC2=C1C(=O)C=C(C=1C=CC(O)=CC=1)O2 HGUVPEBGCAVWID-KETMJRJWSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 235000007756 Akebia quinata Nutrition 0.000 description 2
- 240000008027 Akebia quinata Species 0.000 description 2
- 240000006108 Allium ampeloprasum Species 0.000 description 2
- 235000005254 Allium ampeloprasum Nutrition 0.000 description 2
- 240000002234 Allium sativum Species 0.000 description 2
- 241000219317 Amaranthaceae Species 0.000 description 2
- 208000000044 Amnesia Diseases 0.000 description 2
- 208000031091 Amnestic disease Diseases 0.000 description 2
- 102000013142 Amylases Human genes 0.000 description 2
- 108010065511 Amylases Proteins 0.000 description 2
- 241001124076 Aphididae Species 0.000 description 2
- 241000208173 Apiaceae Species 0.000 description 2
- 241000256844 Apis mellifera Species 0.000 description 2
- 241000209524 Araceae Species 0.000 description 2
- 241000272875 Ardeidae Species 0.000 description 2
- 244000080767 Areca catechu Species 0.000 description 2
- 235000000832 Ayote Nutrition 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 2
- 235000017491 Bambusa tulda Nutrition 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 241000255789 Bombyx mori Species 0.000 description 2
- 206010006002 Bone pain Diseases 0.000 description 2
- 235000011293 Brassica napus Nutrition 0.000 description 2
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 2
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 2
- 206010006326 Breath odour Diseases 0.000 description 2
- 241000703121 Campanula rotundifolia Species 0.000 description 2
- 235000002566 Capsicum Nutrition 0.000 description 2
- 201000009030 Carcinoma Diseases 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 241000251730 Chondrichthyes Species 0.000 description 2
- 206010008909 Chronic Hepatitis Diseases 0.000 description 2
- 235000001759 Citrus maxima Nutrition 0.000 description 2
- 244000276331 Citrus maxima Species 0.000 description 2
- 235000012469 Cleome gynandra Nutrition 0.000 description 2
- 244000227271 Cleome gynandra Species 0.000 description 2
- 244000205754 Colocasia esculenta Species 0.000 description 2
- 235000006481 Colocasia esculenta Nutrition 0.000 description 2
- 241000207782 Convolvulaceae Species 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 241001092040 Crataegus Species 0.000 description 2
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 2
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 2
- 235000009685 Crataegus X maligna Nutrition 0.000 description 2
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 2
- 235000009486 Crataegus bullatus Nutrition 0.000 description 2
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 2
- 235000009682 Crataegus limnophila Nutrition 0.000 description 2
- 235000004423 Crataegus monogyna Nutrition 0.000 description 2
- 235000002313 Crataegus paludosa Nutrition 0.000 description 2
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 2
- 241000544061 Cuculus canorus Species 0.000 description 2
- 235000009854 Cucurbita moschata Nutrition 0.000 description 2
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 description 2
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 2
- 244000055850 Diospyros virginiana Species 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 206010014970 Ephelides Diseases 0.000 description 2
- 208000010228 Erectile Dysfunction Diseases 0.000 description 2
- 241000221017 Euphorbiaceae Species 0.000 description 2
- 208000004929 Facial Paralysis Diseases 0.000 description 2
- 241000272184 Falconiformes Species 0.000 description 2
- 206010016654 Fibrosis Diseases 0.000 description 2
- 241000555712 Forsythia Species 0.000 description 2
- 235000016623 Fragaria vesca Nutrition 0.000 description 2
- 240000009088 Fragaria x ananassa Species 0.000 description 2
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 2
- 208000018522 Gastrointestinal disease Diseases 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 241000511338 Haliaeetus leucocephalus Species 0.000 description 2
- 208000001953 Hypotension Diseases 0.000 description 2
- 208000008081 Intestinal Fistula Diseases 0.000 description 2
- 240000001549 Ipomoea eriocarpa Species 0.000 description 2
- 235000005146 Ipomoea eriocarpa Nutrition 0.000 description 2
- 206010022998 Irritability Diseases 0.000 description 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 2
- 241000218378 Magnolia Species 0.000 description 2
- 241000219071 Malvaceae Species 0.000 description 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 description 2
- 108010000684 Matrix Metalloproteinases Proteins 0.000 description 2
- 208000003351 Melanosis Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 208000008763 Mercury poisoning Diseases 0.000 description 2
- 206010027439 Metal poisoning Diseases 0.000 description 2
- 241000218231 Moraceae Species 0.000 description 2
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 2
- 206010029216 Nervousness Diseases 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 102000011779 Nitric Oxide Synthase Type II Human genes 0.000 description 2
- 108010076864 Nitric Oxide Synthase Type II Proteins 0.000 description 2
- 206010033078 Otitis media Diseases 0.000 description 2
- 235000008753 Papaver somniferum Nutrition 0.000 description 2
- 241000218180 Papaveraceae Species 0.000 description 2
- 239000006002 Pepper Substances 0.000 description 2
- 244000082204 Phyllostachys viridis Species 0.000 description 2
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 2
- 235000016761 Piper aduncum Nutrition 0.000 description 2
- 240000003889 Piper guineense Species 0.000 description 2
- 235000017804 Piper guineense Nutrition 0.000 description 2
- 235000008184 Piper nigrum Nutrition 0.000 description 2
- 206010036018 Pollakiuria Diseases 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 235000010575 Pueraria lobata Nutrition 0.000 description 2
- 244000046146 Pueraria lobata Species 0.000 description 2
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 2
- 208000010476 Respiratory Paralysis Diseases 0.000 description 2
- 206010057190 Respiratory tract infections Diseases 0.000 description 2
- 208000036071 Rhinorrhea Diseases 0.000 description 2
- 206010039101 Rhinorrhoea Diseases 0.000 description 2
- 244000152640 Rhipsalis cassutha Species 0.000 description 2
- 235000012300 Rhipsalis cassutha Nutrition 0.000 description 2
- 241000208422 Rhododendron Species 0.000 description 2
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 2
- 241000109463 Rosa x alba Species 0.000 description 2
- 235000005073 Rosa x alba Nutrition 0.000 description 2
- 241001180876 Saposhnikovia Species 0.000 description 2
- 206010039509 Scab Diseases 0.000 description 2
- 208000034189 Sclerosis Diseases 0.000 description 2
- 244000000231 Sesamum indicum Species 0.000 description 2
- 208000004078 Snake Bites Diseases 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 235000002595 Solanum tuberosum Nutrition 0.000 description 2
- 244000061456 Solanum tuberosum Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 244000223014 Syzygium aromaticum Species 0.000 description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 2
- 206010043376 Tetanus Diseases 0.000 description 2
- 235000015724 Trifolium pratense Nutrition 0.000 description 2
- 235000021307 Triticum Nutrition 0.000 description 2
- 244000098338 Triticum aestivum Species 0.000 description 2
- GLEVLJDDWXEYCO-UHFFFAOYSA-N Trolox Chemical compound O1C(C)(C(O)=O)CCC2=C1C(C)=C(C)C(O)=C2C GLEVLJDDWXEYCO-UHFFFAOYSA-N 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 241001106462 Ulmus Species 0.000 description 2
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 description 2
- 208000036826 VIIth nerve paralysis Diseases 0.000 description 2
- HLXRWTJXGMHOFN-XJSNKYLASA-N Verbenalin Chemical compound O([C@@H]1OC=C([C@H]2C(=O)C[C@H](C)[C@H]21)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HLXRWTJXGMHOFN-XJSNKYLASA-N 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000035508 accumulation Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 238000001467 acupuncture Methods 0.000 description 2
- 230000003679 aging effect Effects 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 description 2
- 230000006986 amnesia Effects 0.000 description 2
- 230000000507 anthelmentic effect Effects 0.000 description 2
- 230000003266 anti-allergic effect Effects 0.000 description 2
- 230000001760 anti-analgesic effect Effects 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 230000000767 anti-ulcer Effects 0.000 description 2
- 229940125716 antipyretic agent Drugs 0.000 description 2
- 239000011425 bamboo Substances 0.000 description 2
- 230000004531 blood pressure lowering effect Effects 0.000 description 2
- 229940116229 borneol Drugs 0.000 description 2
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 150000001746 carotenes Chemical class 0.000 description 2
- 235000005473 carotenes Nutrition 0.000 description 2
- 230000034303 cell budding Effects 0.000 description 2
- 239000006143 cell culture medium Substances 0.000 description 2
- 230000024245 cell differentiation Effects 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 201000009058 cervical adenitis Diseases 0.000 description 2
- 208000012751 cervical lymphadenitis Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000007882 cirrhosis Effects 0.000 description 2
- 208000019425 cirrhosis of liver Diseases 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 206010009887 colitis Diseases 0.000 description 2
- 230000011382 collagen catabolic process Effects 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 2
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 208000000718 duodenal ulcer Diseases 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 230000001605 fetal effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 235000004611 garlic Nutrition 0.000 description 2
- 210000004051 gastric juice Anatomy 0.000 description 2
- 210000004392 genitalia Anatomy 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- 230000000147 hypnotic effect Effects 0.000 description 2
- 230000036543 hypotension Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 231100000535 infertility Toxicity 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000010977 jade Substances 0.000 description 2
- 235000008777 kaempferol Nutrition 0.000 description 2
- 208000017169 kidney disease Diseases 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 201000007270 liver cancer Diseases 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 208000014018 liver neoplasm Diseases 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 239000001630 malic acid Substances 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- 240000004308 marijuana Species 0.000 description 2
- 208000004396 mastitis Diseases 0.000 description 2
- 230000008774 maternal effect Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 208000007106 menorrhagia Diseases 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 230000007102 metabolic function Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 2
- 230000004899 motility Effects 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 201000005111 ocular hyperemia Diseases 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 230000024241 parasitism Effects 0.000 description 2
- 150000002978 peroxides Chemical class 0.000 description 2
- 208000008423 pleurisy Diseases 0.000 description 2
- 208000020016 psychiatric disease Diseases 0.000 description 2
- 235000015136 pumpkin Nutrition 0.000 description 2
- 235000005875 quercetin Nutrition 0.000 description 2
- 229960001285 quercetin Drugs 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 235000013526 red clover Nutrition 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 235000019643 salty taste Nutrition 0.000 description 2
- HGUVPEBGCAVWID-UHFFFAOYSA-N saponarin Natural products OC1C(O)C(O)C(CO)OC1OC(C(=C1O)C2C(C(O)C(O)C(CO)O2)O)=CC2=C1C(=O)C=C(C=1C=CC(O)=CC=1)O2 HGUVPEBGCAVWID-UHFFFAOYSA-N 0.000 description 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 230000008591 skin barrier function Effects 0.000 description 2
- 230000007958 sleep Effects 0.000 description 2
- 238000000527 sonication Methods 0.000 description 2
- 235000019614 sour taste Nutrition 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 206010044008 tonsillitis Diseases 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 2
- 239000002435 venom Substances 0.000 description 2
- 210000001048 venom Anatomy 0.000 description 2
- 231100000611 venom Toxicity 0.000 description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 108010066676 Abrin Proteins 0.000 description 1
- 241001143500 Aceraceae Species 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241001116477 Adenophora triphylla Species 0.000 description 1
- 206010049589 Afterbirth pain Diseases 0.000 description 1
- 235000008553 Allium fistulosum Nutrition 0.000 description 1
- 244000257727 Allium fistulosum Species 0.000 description 1
- 240000001592 Amaranthus caudatus Species 0.000 description 1
- 235000009328 Amaranthus caudatus Nutrition 0.000 description 1
- 206010001986 Amoebic dysentery Diseases 0.000 description 1
- 235000011446 Amygdalus persica Nutrition 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 240000000662 Anethum graveolens Species 0.000 description 1
- 241000271309 Aquilaria crassna Species 0.000 description 1
- 241000239290 Araneae Species 0.000 description 1
- 235000006226 Areca catechu Nutrition 0.000 description 1
- 241000512259 Ascophyllum nodosum Species 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 206010003645 Atopy Diseases 0.000 description 1
- 241000304886 Bacilli Species 0.000 description 1
- 208000006373 Bell palsy Diseases 0.000 description 1
- 241000133570 Berberidaceae Species 0.000 description 1
- 208000003014 Bites and Stings Diseases 0.000 description 1
- 240000008564 Boehmeria nivea Species 0.000 description 1
- 206010051542 Bone fistula Diseases 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 241000123846 Buddleja officinalis Species 0.000 description 1
- 108010075254 C-Peptide Proteins 0.000 description 1
- 101150071146 COX2 gene Proteins 0.000 description 1
- 101100114534 Caenorhabditis elegans ctc-2 gene Proteins 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 241001585001 Calystegia pubescens Species 0.000 description 1
- 241000208671 Campanulaceae Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000722713 Carcharodon carcharias Species 0.000 description 1
- 235000014653 Carica parviflora Nutrition 0.000 description 1
- 244000132059 Carica parviflora Species 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 241000561734 Celosia cristata Species 0.000 description 1
- 241000397426 Centroberyx lineatus Species 0.000 description 1
- 241001233914 Chelidonium majus Species 0.000 description 1
- 206010008469 Chest discomfort Diseases 0.000 description 1
- 201000006082 Chickenpox Diseases 0.000 description 1
- 102000009016 Cholera Toxin Human genes 0.000 description 1
- 108010049048 Cholera Toxin Proteins 0.000 description 1
- 206010008796 Chromaturia Diseases 0.000 description 1
- 241000197236 Chrysanthemoides monilifera Species 0.000 description 1
- 241000320318 Cirsium vulgare Species 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- 241000675108 Citrus tangerina Species 0.000 description 1
- 241000555678 Citrus unshiu Species 0.000 description 1
- 241000272201 Columbiformes Species 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 235000017159 Crataegus pinnatifida Nutrition 0.000 description 1
- 241000657480 Crataegus pinnatifida Species 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 235000009849 Cucumis sativus Nutrition 0.000 description 1
- 241000219122 Cucurbita Species 0.000 description 1
- 240000001980 Cucurbita pepo Species 0.000 description 1
- 244000301850 Cupressus sempervirens Species 0.000 description 1
- 235000003392 Curcuma domestica Nutrition 0.000 description 1
- 244000008991 Curcuma longa Species 0.000 description 1
- 102000010907 Cyclooxygenase 2 Human genes 0.000 description 1
- 108010037462 Cyclooxygenase 2 Proteins 0.000 description 1
- 241000234646 Cyperaceae Species 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 241001310717 Daphne genkwa Species 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 241000406799 Deto Species 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 241000234272 Dioscoreaceae Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 206010013496 Disturbance in attention Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 238000011891 EIA kit Methods 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 241001113324 Elmidae Species 0.000 description 1
- 206010014568 Empyema Diseases 0.000 description 1
- 244000166124 Eucalyptus globulus Species 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 206010015719 Exsanguination Diseases 0.000 description 1
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 1
- 240000008620 Fagopyrum esculentum Species 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010072132 Fracture pain Diseases 0.000 description 1
- 229940123457 Free radical scavenger Drugs 0.000 description 1
- 208000001034 Frostbite Diseases 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 235000008100 Ginkgo biloba Nutrition 0.000 description 1
- 244000194101 Ginkgo biloba Species 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 206010019133 Hangover Diseases 0.000 description 1
- 208000006968 Helminthiasis Diseases 0.000 description 1
- 244000130592 Hibiscus syriacus Species 0.000 description 1
- 235000018081 Hibiscus syriacus Nutrition 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 235000015466 Hierochloe odorata Nutrition 0.000 description 1
- 244000215124 Hierochloe odorata Species 0.000 description 1
- OVSQVDMCBVZWGM-IDRAQACASA-N Hirsutrin Natural products O([C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)C1=C(c2cc(O)c(O)cc2)Oc2c(c(O)cc(O)c2)C1=O OVSQVDMCBVZWGM-IDRAQACASA-N 0.000 description 1
- 244000010000 Hovenia dulcis Species 0.000 description 1
- 235000014486 Hydrangea macrophylla Nutrition 0.000 description 1
- 244000267823 Hydrangea macrophylla Species 0.000 description 1
- 240000004890 Hygrophila ringens Species 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- FVQOMEDMFUMIMO-UHFFFAOYSA-N Hyperosid Natural products OC1C(O)C(O)C(CO)OC1OC1C(=O)C2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 FVQOMEDMFUMIMO-UHFFFAOYSA-N 0.000 description 1
- 206010020850 Hyperthyroidism Diseases 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 101710116034 Immunity protein Proteins 0.000 description 1
- 235000015912 Impatiens biflora Nutrition 0.000 description 1
- 244000018716 Impatiens biflora Species 0.000 description 1
- 240000007171 Imperata cylindrica Species 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010022653 Intestinal haemorrhages Diseases 0.000 description 1
- 241000253121 Inula britannica Species 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 241000242027 Jasminum floridum Species 0.000 description 1
- 241000721662 Juniperus Species 0.000 description 1
- 206010023799 Large intestinal ulcer Diseases 0.000 description 1
- 201000008197 Laryngitis Diseases 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 206010024453 Ligament sprain Diseases 0.000 description 1
- 241000234435 Lilium Species 0.000 description 1
- 235000012857 Lindera obtusiloba Nutrition 0.000 description 1
- 240000006370 Lindera obtusiloba Species 0.000 description 1
- AMBQHHVBBHTQBF-UHFFFAOYSA-N Loganin Natural products C12C(C)C(O)CC2C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O AMBQHHVBBHTQBF-UHFFFAOYSA-N 0.000 description 1
- 235000017617 Lonicera japonica Nutrition 0.000 description 1
- 244000167230 Lonicera japonica Species 0.000 description 1
- 241000488974 Loranthus Species 0.000 description 1
- 235000003956 Luffa Nutrition 0.000 description 1
- 244000050983 Luffa operculata Species 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 240000000982 Malva neglecta Species 0.000 description 1
- 235000000060 Malva neglecta Nutrition 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 206010065334 Mucosal hyperaemia Diseases 0.000 description 1
- 208000005647 Mumps Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 235000003805 Musa ABB Group Nutrition 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 206010028391 Musculoskeletal Pain Diseases 0.000 description 1
- 206010052904 Musculoskeletal stiffness Diseases 0.000 description 1
- 229930192627 Naphthoquinone Natural products 0.000 description 1
- 241000234479 Narcissus Species 0.000 description 1
- 208000000592 Nasal Polyps Diseases 0.000 description 1
- 206010028729 Nasal cavity cancer Diseases 0.000 description 1
- 241000588652 Neisseria gonorrhoeae Species 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- 244000183278 Nephelium litchi Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 241000209477 Nymphaeaceae Species 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 241000238633 Odonata Species 0.000 description 1
- 240000001659 Oldenlandia diffusa Species 0.000 description 1
- 239000008896 Opium Substances 0.000 description 1
- 240000001439 Opuntia Species 0.000 description 1
- 235000013389 Opuntia humifusa var. humifusa Nutrition 0.000 description 1
- 206010031009 Oral pain Diseases 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 101150000187 PTGS2 gene Proteins 0.000 description 1
- 235000006484 Paeonia officinalis Nutrition 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 240000001090 Papaver somniferum Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 206010057249 Phagocytosis Diseases 0.000 description 1
- 244000081757 Phalaris arundinacea Species 0.000 description 1
- 235000010717 Phyllostachys nigra Nutrition 0.000 description 1
- 240000005827 Phyllostachys nigra Species 0.000 description 1
- 241000218641 Pinaceae Species 0.000 description 1
- 235000000405 Pinus densiflora Nutrition 0.000 description 1
- 240000008670 Pinus densiflora Species 0.000 description 1
- 235000015266 Plantago major Nutrition 0.000 description 1
- 241000745768 Pluchea carolinensis Species 0.000 description 1
- 208000005374 Poisoning Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000283080 Proboscidea <mammal> Species 0.000 description 1
- 102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 description 1
- 108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 description 1
- 235000009827 Prunus armeniaca Nutrition 0.000 description 1
- 244000018633 Prunus armeniaca Species 0.000 description 1
- 240000002381 Prunus davidiana Species 0.000 description 1
- 206010037093 Pruritus genital Diseases 0.000 description 1
- 241000554910 Pulsatilla cernua var. koreana Species 0.000 description 1
- 241000282374 Puma concolor Species 0.000 description 1
- 244000294611 Punica granatum Species 0.000 description 1
- 235000014360 Punica granatum Nutrition 0.000 description 1
- 206010037596 Pyelonephritis Diseases 0.000 description 1
- 206010037597 Pyelonephritis acute Diseases 0.000 description 1
- 206010037601 Pyelonephritis chronic Diseases 0.000 description 1
- 235000016979 Quercus ilex Nutrition 0.000 description 1
- 240000004127 Quercus ilex Species 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 244000088415 Raphanus sativus Species 0.000 description 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 description 1
- 241000282806 Rhinoceros Species 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 241000109329 Rosa xanthina Species 0.000 description 1
- 241001107098 Rubiaceae Species 0.000 description 1
- 240000007651 Rubus glaucus Species 0.000 description 1
- 235000011034 Rubus glaucus Nutrition 0.000 description 1
- 235000009122 Rubus idaeus Nutrition 0.000 description 1
- YDBYJHTYSHBBAU-YFKPBYRVSA-N S-methyl-L-methioninate Chemical compound C[S+](C)CC[C@H](N)C([O-])=O YDBYJHTYSHBBAU-YFKPBYRVSA-N 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 235000017276 Salvia Nutrition 0.000 description 1
- 240000007164 Salvia officinalis Species 0.000 description 1
- 241000580955 Sapindus mukorossi Species 0.000 description 1
- GMBQZIIUCVWOCD-WWASVFFGSA-N Sarsapogenine Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CC[C@H](O)C[C@H]4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@H](C)CO1 GMBQZIIUCVWOCD-WWASVFFGSA-N 0.000 description 1
- 240000005499 Sasa Species 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 244000040738 Sesamum orientale Species 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 208000007613 Shoulder Pain Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010052891 Skin bacterial infection Diseases 0.000 description 1
- 206010041133 Small intestine ulcer Diseases 0.000 description 1
- 235000010586 Sophora japonica Nutrition 0.000 description 1
- 244000046101 Sophora japonica Species 0.000 description 1
- 240000003829 Sorghum propinquum Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 208000010040 Sprains and Strains Diseases 0.000 description 1
- 206010041899 Stab wound Diseases 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 241000193998 Streptococcus pneumoniae Species 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 240000001949 Taraxacum officinale Species 0.000 description 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 208000000491 Tendinopathy Diseases 0.000 description 1
- 206010043255 Tendonitis Diseases 0.000 description 1
- 241000001522 Terminalia chebula Species 0.000 description 1
- 235000011517 Terminalia chebula Nutrition 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 206010043515 Throat cancer Diseases 0.000 description 1
- RTMWIZOXNKJHRE-UHFFFAOYSA-N Tigogenin Natural products CC1COC2CC(C)(OC12)C3CCC4C5CCC6CC(O)CCC6(C)C5CCC34C RTMWIZOXNKJHRE-UHFFFAOYSA-N 0.000 description 1
- 241000121220 Tricholoma matsutake Species 0.000 description 1
- 235000004869 Tussilago farfara Nutrition 0.000 description 1
- 240000000377 Tussilago farfara Species 0.000 description 1
- 241001518821 Typha orientalis Species 0.000 description 1
- 241001300088 Ulmus macrocarpa Species 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 208000009911 Urinary Calculi Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 206010046910 Vaginal haemorrhage Diseases 0.000 description 1
- 206010046980 Varicella Diseases 0.000 description 1
- 206010047139 Vasoconstriction Diseases 0.000 description 1
- HLXRWTJXGMHOFN-UHFFFAOYSA-N Verbenalin Natural products C12C(C)CC(=O)C2C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O HLXRWTJXGMHOFN-UHFFFAOYSA-N 0.000 description 1
- 235000011453 Vigna umbellata Nutrition 0.000 description 1
- 240000001417 Vigna umbellata Species 0.000 description 1
- 241000863480 Vinca Species 0.000 description 1
- 241000028204 Vincetoxicum atratum Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 240000008866 Ziziphus nummularia Species 0.000 description 1
- 241001123263 Zostera Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- XYUNNDAEUQFHGV-UHFFFAOYSA-N [Se].[Se] Chemical compound [Se].[Se] XYUNNDAEUQFHGV-UHFFFAOYSA-N 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 235000009962 acacetin Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 235000019647 acidic taste Nutrition 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 201000001555 acute pyelonephritis Diseases 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000019552 anatomical structure morphogenesis Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 229940124339 anthelmintic agent Drugs 0.000 description 1
- 239000000921 anthelmintic agent Substances 0.000 description 1
- 235000010208 anthocyanin Nutrition 0.000 description 1
- 239000004410 anthocyanin Substances 0.000 description 1
- 229930002877 anthocyanin Natural products 0.000 description 1
- 150000004636 anthocyanins Chemical class 0.000 description 1
- 230000002686 anti-diuretic effect Effects 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 239000000729 antidote Substances 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 229940124575 antispasmodic agent Drugs 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 244000240481 arrow poison Species 0.000 description 1
- 208000015337 arteriosclerotic cardiovascular disease Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 239000010426 asphalt Substances 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000007215 black sesame Nutrition 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 208000024330 bloating Diseases 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 235000009120 camo Nutrition 0.000 description 1
- 230000004856 capillary permeability Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229910002091 carbon monoxide Inorganic materials 0.000 description 1
- 239000000496 cardiotonic agent Substances 0.000 description 1
- 241001233037 catfish Species 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000003850 cellular structure Anatomy 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 210000004720 cerebrum Anatomy 0.000 description 1
- 235000005607 chanvre indien Nutrition 0.000 description 1
- 208000003167 cholangitis Diseases 0.000 description 1
- 201000001352 cholecystitis Diseases 0.000 description 1
- 201000001883 cholelithiasis Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 201000006368 chronic pyelonephritis Diseases 0.000 description 1
- 235000019504 cigarettes Nutrition 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 230000037319 collagen production Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 235000003373 curcuma longa Nutrition 0.000 description 1
- 235000021438 curry Nutrition 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000005034 decoration Methods 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 229940111205 diastase Drugs 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 235000011869 dried fruits Nutrition 0.000 description 1
- 230000002183 duodenal effect Effects 0.000 description 1
- 208000010515 dystocia Diseases 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000002892 effect on hypertension Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 230000007368 endocrine function Effects 0.000 description 1
- 210000000750 endocrine system Anatomy 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 241001233957 eudicotyledons Species 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 229940066493 expectorants Drugs 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 210000000720 eyelash Anatomy 0.000 description 1
- 235000021107 fermented food Nutrition 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 235000012055 fruits and vegetables Nutrition 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 239000000118 hair dye Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000024798 heartburn Diseases 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 239000011487 hemp Substances 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000002631 hypothermal effect Effects 0.000 description 1
- 210000002865 immune cell Anatomy 0.000 description 1
- 230000004957 immunoregulator effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- OVSQVDMCBVZWGM-QCKGUQPXSA-N isoquercetin Natural products OC[C@@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O OVSQVDMCBVZWGM-QCKGUQPXSA-N 0.000 description 1
- 230000005722 itchiness Effects 0.000 description 1
- 239000003350 kerosene Substances 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 229940125722 laxative agent Drugs 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 230000005976 liver dysfunction Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- AMBQHHVBBHTQBF-UOUCRYGSSA-N loganin Chemical compound O([C@@H]1OC=C([C@H]2C[C@H](O)[C@H](C)[C@H]21)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O AMBQHHVBBHTQBF-UOUCRYGSSA-N 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 208000010805 mumps infectious disease Diseases 0.000 description 1
- 150000002791 naphthoquinones Chemical class 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 208000005346 nocturnal enuresis Diseases 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 239000003883 ointment base Substances 0.000 description 1
- 229960001027 opium Drugs 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229940124595 oriental medicine Drugs 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 208000021090 palsy Diseases 0.000 description 1
- 230000001769 paralizing effect Effects 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 208000014837 parasitic helminthiasis infectious disease Diseases 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 210000000578 peripheral nerve Anatomy 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 206010034674 peritonitis Diseases 0.000 description 1
- 230000008782 phagocytosis Effects 0.000 description 1
- 238000006552 photochemical reaction Methods 0.000 description 1
- 235000021110 pickles Nutrition 0.000 description 1
- 210000004694 pigment cell Anatomy 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 235000019633 pungent taste Nutrition 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- OVSQVDMCBVZWGM-QSOFNFLRSA-N quercetin 3-O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-QSOFNFLRSA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 208000016691 refractory malignant neoplasm Diseases 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000029865 regulation of blood pressure Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 230000001850 reproductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 208000026451 salivation Diseases 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 229940076279 serotonin Drugs 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 230000009329 sexual behaviour Effects 0.000 description 1
- 235000020083 shōchū Nutrition 0.000 description 1
- 230000012232 skeletal muscle contraction Effects 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 231100000046 skin rash Toxicity 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000003998 snake venom Substances 0.000 description 1
- 206010041232 sneezing Diseases 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 230000001150 spermicidal effect Effects 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 208000002254 stillbirth Diseases 0.000 description 1
- 231100000537 stillbirth Toxicity 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 201000004415 tendinitis Diseases 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000006211 transdermal dosage form Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- SWGJCIMEBVHMTA-UHFFFAOYSA-K trisodium;6-oxido-4-sulfo-5-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2-sulfonate Chemical compound [Na+].[Na+].[Na+].C1=CC=C2C(N=NC3=C4C(=CC(=CC4=CC=C3O)S([O-])(=O)=O)S([O-])(=O)=O)=CC=C(S([O-])(=O)=O)C2=C1 SWGJCIMEBVHMTA-UHFFFAOYSA-K 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 235000013976 turmeric Nutrition 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 208000026533 urinary bladder disease Diseases 0.000 description 1
- 208000022934 urinary frequency Diseases 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 230000036318 urination frequency Effects 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 230000013948 uterine smooth muscle contraction Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000025033 vasoconstriction Effects 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 231100000925 very toxic Toxicity 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000004260 weight control Methods 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
- 235000001459 whitebark Nutrition 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020110109287A KR101868050B1 (ko) | 2011-10-25 | 2011-10-25 | 약용 꽃을 활용한 쌈 발효법 및 이를 활용한 피부 외용제 조성물 |
| KR10-2011-0109287 | 2011-10-25 | ||
| PCT/KR2012/008541 WO2013062266A2 (ko) | 2011-10-25 | 2012-10-18 | 약용 꽃을 활용한 쌈 발효법 및 이를 활용한 피부 외용제 조성물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014530905A JP2014530905A (ja) | 2014-11-20 |
| JP6077554B2 true JP6077554B2 (ja) | 2017-02-08 |
Family
ID=48168715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014538700A Expired - Fee Related JP6077554B2 (ja) | 2011-10-25 | 2012-10-18 | 薬用花を活用した包み発酵法およびこれを活用した皮膚外用剤組成物 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP6077554B2 (ko) |
| KR (1) | KR101868050B1 (ko) |
| CN (1) | CN103906526B (ko) |
| WO (1) | WO2013062266A2 (ko) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102670748B1 (ko) * | 2023-09-05 | 2024-05-30 | 한국콜마주식회사 | 손상 피부 개선용 화장료 조성물 |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101523554B1 (ko) * | 2014-04-07 | 2015-05-29 | 노병승 | 아토피 피부질환 개선용 한방비누 제조 방법 |
| CN104027286A (zh) * | 2014-07-07 | 2014-09-10 | 广州丹奇日用化工厂有限公司 | 延缓皮肤衰老化妆品组合物及其制备方法 |
| KR101753304B1 (ko) * | 2014-08-11 | 2017-07-04 | 경희대학교 산학협력단 | 피부 미백용 화장료 조성물 |
| CN104188857B (zh) * | 2014-08-22 | 2017-01-11 | 广东药科大学 | 一种中药美白淡斑霜及其制备方法 |
| CN104146942A (zh) * | 2014-08-29 | 2014-11-19 | 桂林市艾康科技有限公司 | 一种抗炎症抗衰的竹液面膜 |
| KR101665978B1 (ko) * | 2014-10-13 | 2016-10-13 | 주식회사 코리아나화장품 | 우수한 피부 침투율을 갖는 미세거품 형성용 화장료 조성물 |
| KR102247965B1 (ko) * | 2014-10-17 | 2021-05-04 | 주식회사 코리아나화장품 | 옥수수수염 발효액을 포함하는 피부 미백용 화장료 조성물 |
| CN104434650B (zh) * | 2014-11-18 | 2017-10-03 | 皖南医学院 | 一种能宁神舒压的美白保湿赋能乳液及其制备方法 |
| KR101548231B1 (ko) * | 2015-01-21 | 2015-09-10 | 한방약초힐링 농업회사법인주식회사 | 봉선화 추출물을 이용한 남성세안제 제조방법 |
| KR101667284B1 (ko) | 2015-05-12 | 2016-10-18 | 충남대학교산학협력단 | 흑삼 및 혼합 생약의 발효 추출물을 함유하는 화장료 조성물 |
| CN106309613B (zh) * | 2015-07-01 | 2020-07-21 | 莱博药妆技术（上海）股份有限公司 | 具有抗炎、抗过敏作用的中药及其制备方法 |
| KR101666348B1 (ko) * | 2015-08-12 | 2016-10-17 | 김수경 | 백하수오를 포함하는 천연유래물질을 이용한 피부 주름 개선 또는 피부 탄력 증진용 화장료 조성물의 제조방법 및 이에 따라 제조된 화장료 조성물 |
| KR102397975B1 (ko) * | 2015-09-10 | 2022-05-12 | 주식회사 엘지생활건강 | 키레놀을 포함하는 피부 보습용 피부외용제 조성물 |
| WO2017051950A1 (ko) * | 2015-09-24 | 2017-03-30 | 노병승 | 아토피 피부질환 개선용 한방비누 제조 방법 |
| KR101738340B1 (ko) * | 2015-11-30 | 2017-05-22 | 한국 한의학 연구원 | 황련 및 괄루인 혼합 추출물을 유효성분으로 함유하는 피부 노화 및 주름 개선용 조성물 |
| KR101789518B1 (ko) * | 2015-11-30 | 2017-10-26 | 한국 한의학 연구원 | 황금 및 나복자 혼합 추출물을 유효성분으로 함유하는 피부 노화 및 주름 개선용 조성물 |
| CN105395467B (zh) * | 2015-12-01 | 2018-09-21 | 山东皓尔生物工程有限公司 | 一种中药组合物、美肤化妆品及其应用 |
| CN105342933B (zh) * | 2015-12-09 | 2018-03-13 | 安徽中医药大学 | 一种中药复方洁面泡腾片及其制备方法 |
| CN105560097B (zh) * | 2015-12-21 | 2018-04-17 | 天津贝世康科技有限公司 | 一种牡丹鲜花酵素及其制备方法和用途 |
| KR101833727B1 (ko) | 2016-05-13 | 2018-02-28 | 정규헌 | 세균의 소독이 가능한 물치약과 그 조성물 |
| CN105943444A (zh) * | 2016-06-07 | 2016-09-21 | 胡小丽 | 一种孕妇护理膏的制备方法 |
| CN105816740A (zh) * | 2016-06-09 | 2016-08-03 | 童松 | 一种燥湿化痰健脑酒 |
| CN106074677B (zh) * | 2016-08-05 | 2020-12-22 | 山东大学 | 一种防治皮肤病变老化的中药组合物及其应用 |
| KR102008485B1 (ko) * | 2016-12-15 | 2019-08-07 | 주식회사 엘지생활건강 | 침향 추출물을 포함하는 피부 보습용 화장료 조성물 |
| JP2020502172A (ja) * | 2016-12-15 | 2020-01-23 | エルジー ハウスホールド アンド ヘルスケア リミテッド | 漢方薬抽出物を有効成分として含む化粧料組成物 |
| CN106511180A (zh) * | 2016-12-22 | 2017-03-22 | 北京工商大学 | 一种党参发酵原浆化妆品及其制备方法与应用 |
| CN106510351A (zh) * | 2017-01-04 | 2017-03-22 | 上海紫醇生物科技有限公司 | 红豆杉中药安睡枕 |
| CN107137319A (zh) * | 2017-05-31 | 2017-09-08 | 上海东晟源日化有限公司 | 一种奈米柔敏排毒养颜霜 |
| JP2019011279A (ja) * | 2017-06-30 | 2019-01-24 | 小林製薬株式会社 | 下痢抑制剤 |
| KR102014602B1 (ko) * | 2017-10-19 | 2019-08-29 | 주식회사 삼성인터네셔널 | 기미 개선용 화장료 조성물 |
| US11452752B2 (en) | 2017-10-27 | 2022-09-27 | Natural Endotech Co., Ltd. | Composition for antioxidation, anti-inflammation, or osteoclast differentiation inhibition |
| CN107951800A (zh) * | 2017-12-03 | 2018-04-24 | 同济大学 | 一种具有抗衰祛皱提拉紧致功效的中药组合物及其制备方法 |
| CN107951822A (zh) * | 2017-12-05 | 2018-04-24 | 广州赛莱拉干细胞科技股份有限公司 | 一种含有枸杞干细胞提取物净白护肤品 |
| CN107929563A (zh) * | 2017-12-20 | 2018-04-20 | 贵州三力制药股份有限公司 | 强力天麻杜仲胶囊及其成分检测方法 |
| KR102012000B1 (ko) * | 2018-01-16 | 2019-08-19 | 김경희 | 문신 부위 감염방지용 코팅 조성물 및 이의 제조방법 |
| CN108042433B (zh) * | 2018-01-17 | 2023-01-17 | 广州环亚化妆品科技股份有限公司 | 一种美白抗氧化植物组合物、植物组合物发酵液及制备方法和用途 |
| KR102088728B1 (ko) * | 2018-01-19 | 2020-03-16 | (주)에스디생명공학 | 식물 복합추출물을 유효성분으로 함유하는 피부 탄력 및 주름 개선용 화장료 조성물 |
| CN108354868A (zh) * | 2018-04-28 | 2018-08-03 | 云南省药物研究所 | 一种植物美白和抗氧化组合物及其日化品的制备与应用 |
| KR102032873B1 (ko) * | 2018-06-05 | 2019-11-08 | 재단법인 남원시화장품산업지원센터 | 항산화 및 보습용 화장료 조성물 |
| CN109846771B (zh) * | 2018-07-05 | 2024-06-28 | 上海珈凯生物股份有限公司 | 一种具有祛痘功效的植物提取物组合物及其制备方法 |
| CN109381406B (zh) * | 2018-09-17 | 2022-05-10 | 士齐生物研发中心（苏州工业园区）有限公司 | 一种具有抗衰老作用的化妆品组合物的制备方法及其应用 |
| CN109846762B (zh) * | 2018-09-17 | 2022-02-11 | 上海珈凯生物科技有限公司 | 一种具有美白功效的组合物及其制备方法、应用 |
| KR102145113B1 (ko) | 2018-12-13 | 2020-08-18 | (주) 에이텍 | 유성온천수를 이용한 능이와 신이의 온천수발효추출물 함유 화장료 조성물 |
| CN109674734A (zh) * | 2019-01-22 | 2019-04-26 | 郑娇娇 | 一种具有保湿、修护、舒缓、抗衰作用的组合成分及其应用 |
| KR102187896B1 (ko) * | 2019-01-24 | 2020-12-08 | 주식회사 코씨드바이오팜 | 식물추출물을 함유하는 세포보습, 세포간 보습, 피부 장벽보습에 효과적인 화장료 조성물 |
| KR102196051B1 (ko) | 2019-01-25 | 2020-12-29 | (주)월드코스텍 | 인진쑥 발효물을 포함하는 피부 기능성 조성물 |
| KR102073349B1 (ko) * | 2019-03-11 | 2020-02-05 | 대한바이오팜 주식회사 | 한약재 추출물을 포함하는 피부 주름 개선, 피부 미백 및 항염증용 조성물 |
| CN109806190A (zh) * | 2019-04-04 | 2019-05-28 | 烟台新时代健康产业日化有限公司 | 一种松花粉的发酵提取工艺 |
| KR102667503B1 (ko) * | 2019-07-03 | 2024-05-20 | 쑨 후앙 | 여드름 제거용 안면 마스크 |
| CN110669598A (zh) * | 2019-10-18 | 2020-01-10 | 王晓孟 | 一种中药洗发皂及其制备方法 |
| KR102123645B1 (ko) * | 2019-10-22 | 2020-06-18 | 주식회사 코씨드바이오팜 | 갯강활추출물을 함유하는 화장료 조성물 |
| KR102149223B1 (ko) * | 2019-12-13 | 2020-08-28 | 주식회사 인투바이오 | 천연 복합발효 추출물을 함유하는 피부미백용 화장료 조성물 |
| WO2021182873A1 (en) * | 2020-03-13 | 2021-09-16 | Medihelpline Co., Ltd. | A topical composition comprising an extract of combined herbs comprising longanae arillus for the skin regeneration and the treatment or alleviation of skin wound and the use thereof. |
| EP4117700A4 (en) * | 2020-03-13 | 2024-01-24 | Medihelpline Co., Ltd. | TOPICAL COMPOSITION COMPRISING COMBINED HERBS EXTRACT COMPRISING LONGANAE ARILLUS FOR INHIBITION OF TLSP AND TREATMENT OR RELIEF OF INFLAMMATORY SKIN DISEASE AND USE THEREOF |
| KR102338399B1 (ko) * | 2020-06-10 | 2021-12-13 | 주식회사 코씨드바이오팜 | 천지단 추출물을 유효성분으로 함유하는 화장료 조성물 |
| WO2022023784A1 (en) * | 2020-07-31 | 2022-02-03 | Meiqing Gong | Add scented natural materials and spiritual healing mixtures to mask |
| KR102557706B1 (ko) * | 2020-08-18 | 2023-07-24 | 주식회사 포러스젠 | 사포나린 및 영지버섯 추출물을 포함하는 피부보호용 화장료 조성물 |
| KR102219382B1 (ko) * | 2020-12-02 | 2021-02-22 | 얼라이드 탑 (홍콩) 인더스트리얼 리미티드 | 천연 식물 혼합발효추출물을 유효성분으로 함유하는 피부 개선용 화장료 조성물 |
| KR102570858B1 (ko) * | 2020-12-23 | 2023-08-28 | 전라남도 | 아로마테라피용 피부 마사지 화장료 조성물 |
| KR102570019B1 (ko) * | 2020-12-23 | 2023-08-23 | 전라남도 | 아로마테라피 효과가 있는 발마사지용 화장료 조성물 |
| TWI774331B (zh) * | 2021-04-22 | 2022-08-11 | 大陸商上海全麗生物科技有限公司 | 玉蘭花燕麥醱酵物、其製造方法及含其之外用組成物 |
| KR102342695B1 (ko) | 2021-07-14 | 2021-12-24 | 에이드코리아컴퍼니 주식회사 | 피부진정용 화장료 조성물 |
| CN114099407A (zh) * | 2021-09-09 | 2022-03-01 | 四川省宜宾高洲酒业有限责任公司 | 一种天然多效护肤液的制备方法 |
| CN114712293A (zh) * | 2022-05-10 | 2022-07-08 | 广东瀚润生物科技有限公司 | 天然植萃草本组合物、其制备方法及其应用 |
| CN115645347A (zh) * | 2022-12-15 | 2023-01-31 | 北京九州益华化妆品有限公司 | 一种发酵型防脱洗发水及其制备方法 |
| CN116920049B (zh) * | 2023-07-12 | 2024-05-31 | 中南民族大学 | 一种治疗胃溃疡的生肤油及其制备方法和应用 |
| CN117223809B (zh) * | 2023-11-10 | 2024-02-02 | 山东向日葵生物工程有限公司 | 一种消炎利尿的发酵乳杆菌sf-l35发酵药用饮品及应用 |
| CN117646038B (zh) * | 2024-01-30 | 2024-04-19 | 妙越缇卡生物医药科技(山东)有限公司 | 美白淡斑的副干酪乳杆菌sf-l31发酵物及其应用 |
| CN117731712B (zh) * | 2024-02-20 | 2024-05-17 | 潍坊舒珍堂制药有限公司 | 一种活血舒筋中药酊剂生产方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1060011A (zh) * | 1991-07-24 | 1992-04-08 | 林新水 | 一种“观音人参皇”茶叶的制备法 |
| CN101503658A (zh) * | 2009-03-06 | 2009-08-12 | 杨凌天力生物技术有限公司 | 一种产苦马豆素的内生真菌的分离方法 |
| KR20110096102A (ko) * | 2010-02-12 | 2011-08-29 | 주식회사 케이씨아이 | 천연 원료 추출물을 포함하는 항균 조성물, 복합 천연 방부제 및 이들의 제조방법 |
| KR101202367B1 (ko) * | 2010-03-19 | 2012-11-16 | 주식회사 콧데 | 회화나무꽃 추출물의 누룩 발효물을 함유하는 여드름 개선용 조성물 |
| WO2011126295A2 (ko) * | 2010-04-06 | 2011-10-13 | (주)아모레퍼시픽 | 약용 잎을 활용한 쌈 발효법 및 이를 활용한 피부 외용제 조성물 |
| KR101042845B1 (ko) * | 2011-05-30 | 2011-06-17 | 이노스킨 주식회사 | 괴화 및 미강 발효 추출물을 함유하는 괴화 및 미강 발효 추출물의 제조방법 및 이를 함유하는 노화방지, 악건성, 가려움용 화장료 조성물 |
-
2011
- 2011-10-25 KR KR1020110109287A patent/KR101868050B1/ko active IP Right Grant
-
2012
- 2012-10-18 WO PCT/KR2012/008541 patent/WO2013062266A2/ko active Application Filing
- 2012-10-18 CN CN201280052868.5A patent/CN103906526B/zh not_active Expired - Fee Related
- 2012-10-18 JP JP2014538700A patent/JP6077554B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102670748B1 (ko) * | 2023-09-05 | 2024-05-30 | 한국콜마주식회사 | 손상 피부 개선용 화장료 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR101868050B1 (ko) | 2018-06-18 |
| CN103906526B (zh) | 2017-07-14 |
| JP2014530905A (ja) | 2014-11-20 |
| KR20130047778A (ko) | 2013-05-09 |
| WO2013062266A3 (ko) | 2013-06-20 |
| WO2013062266A2 (ko) | 2013-05-02 |
| CN103906526A (zh) | 2014-07-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6077554B2 (ja) | 薬用花を活用した包み発酵法およびこれを活用した皮膚外用剤組成物 | |
| KR101805004B1 (ko) | 약용 잎을 활용한 쌈 발효법 및 이를 활용한 피부 외용제 조성물 | |
| JP5864252B2 (ja) | 炮製を活用した薬用植物抽出物及びこれを含有する皮膚外用剤組成物 | |
| Bakhru | Herbs that heal: natural remedies for good health | |
| Guarino et al. | Ethnobotanical study of the Sannio area, Campania, southern Italy | |
| KR20130086682A (ko) | 골장회복 하수오와 홍삼녹용과 오가피등 100가지한약재 추출물 드링크제 및제조 방법 | |
| JP2005501851A (ja) | 毒素を除去するための組成物 | |
| KR20160087114A (ko) | 꽃을 이용한 식품첨가제 | |
| Hutchens | A Handbook of Native American Herbs: The Pocket Guide to 125 Medicinal Plants and Their Uses | |
| KR20160087112A (ko) | 꽃차 및 이의 제조방법 | |
| KR20160087113A (ko) | 꽃을 함유하는 화장품 | |
| CN107156828A (zh) | 一种适用于炎性肠病患者的全营养配方食品 | |
| CN105010669A (zh) | 一种清润保健茉莉花茶及其生产方法 | |
| KR100873033B1 (ko) | 마사지팩용 화장료 조성물 | |
| KR20090032158A (ko) | 가압전이(加壓轉移)에 의한 과일 침출 및 액상 차 조성물과 그 제조방법 | |
| CN106333010A (zh) | 一种袋泡减肥瘦身茶及其制备方法 | |
| CN105326753A (zh) | 一种淡化唇纹滋养唇膏及其制备方法 | |
| KR101334827B1 (ko) | 참외씨오일을 주성분으로 하는 미용 팩 제조방법 | |
| CN102886014A (zh) | 一种清血消炎的抗肿瘤药物 | |
| KR100989944B1 (ko) | 항산화 미백 활성을 갖는 생약 혼합 추출물 | |
| KR20180089696A (ko) | 천연식물 추출물의 잔류농약 제거방법 | |
| CN103892475A (zh) | 保健文胸 | |
| CN107156829A (zh) | 一种适用于肝病患者的全营养配方食品 | |
| KR100903827B1 (ko) | 수제 한방 비누 및 그 제조방법 | |
| De et al. | Nutrient rich foods in human diet as immunity boosters |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150924 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160705 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20160930 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20161202 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20161227 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170112 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6077554 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |