JP6077554B2 - Wrapping fermentation method using medicinal flowers and skin external preparation composition using the method - Google Patents

Description

  The present invention relates to a composition for external application to the skin containing a packaged fermented extract using medicinal flowers, and more specifically, a package manufactured by fermenting natural products by wrapping or covering them with medicinal flowers. The present invention relates to a skin external preparation composition containing a fermented extract and excellent in skin antioxidant, anti-aging, whitening and moisturizing effects.

  Human skin changes with age due to various internal and external factors. That is, internally, secretion of various hormones that regulate metabolism decreases, immune cell functions and cell activities decrease, biosynthesis of immunity proteins and biological proteins necessary for the living body is reduced, and external As the ozone layer is destroyed, the content of ultraviolet rays reaching the surface of the sun increases, and as environmental pollution becomes more serious, free radicals and active harmful oxygen increase, resulting in increased skin thickness. Not only does this decrease, wrinkles increase, and elasticity decreases, but it also causes various changes such as dullness of the skin, faint skin troubles, increased spots, freckles and senile spots.

  As aging progresses, symptoms such as changes or decrease in the content and sequence of collagen, elastin, hyaluronic acid, and glycoproteins that constitute the skin appear, and oxidative stress caused by free radicals and active harmful oxygen Become. In addition, the aging of the cells and the majority of the cells that make up the skin by ultraviolet rays, cyclooxygenase-2 (Cox-2, cyclooxygenase) is an enzyme that produces inflammatory cytokines that are said to cause inflammation. Biosynthesis of matrix metalloproteinase (MMP), an enzyme that degrades skin tissue by these inflammatory factors, has increased, and NO (nitric oxide) by iNOS (inducible nitric oxide synthase) has increased. It is known that the production of is increased. In other words, the decrease in cellular activity due to spontaneous aging and microinflammation reduce the biosynthesis of substrate substances, which are degraded by external factors such as increased stress due to various harmful environments and increased reactive oxygen species due to sunlight. And as degeneration is accelerated and the skin matrix is destroyed and thinned, the symptoms of skin aging appear. Therefore, in reality, many studies have been conducted on active ingredients that can prevent and improve such an aging phenomenon.

  On the other hand, active oxygen generated by various physical, chemical, and environmental factors such as internal enzyme systems, reductive metabolism, chemicals, pollutants, and photochemical reactions is a component of lipids, proteins, sugars, and cell components. It is known that non-selective and irreversible destruction of DNA and the like causes various diseases including cell aging or cancer. In addition, various body peroxides including lipid peroxides generated as a result of lipid peroxidation by these active oxygens cause various dysfunctions by causing oxidative destruction to cells and causing various dysfunctions. It may cause. Therefore, antioxidants such as free radical scavengers or peroxide formation inhibitors are expected as agents for inhibiting or treating aging and various diseases caused by these oxides. The

  Recently, there has been an increasing demand for a fermentation method for natural products using a natural fermentation method in which no artificial element is added due to a tendency such as well-being, and a demand for a product utilizing this has continued. However, such a natural fermentation method is difficult to actually use as a product due to the risk of rot and contamination caused by macrophages and anaerobic bacteria harmful to the human body. In order to solve this, a sterilization method before fermentation such as a boiling method has been devised. However, since effective components can be destroyed by heat, it is necessary to develop a fermentation method by a non-sterilization method.

  Recently, with increasing interest in traditional fermented foods, various methods for producing extracts using such fermentation techniques have been developed. As a result, the development of functional foods, cosmetics, and the like utilizing natural product extracts having performance superior to that of existing natural products by fermenting natural products and the like continues.

  Therefore, as a result of repeated research to develop a natural product extract having performance superior to that of existing natural products, the present inventors have compared natural products with simple natural product extracts and fermented extracts. The present invention was completed by discovering that a fermented wrap extract produced by fermenting by covering or covering a flower with a medicinal flower is far superior in skin antioxidant, anti-aging, whitening and moisturizing effects.

  Accordingly, an object of the present invention is to provide a skin external preparation composition containing a packaged fermented extract excellent in skin efficacy and excellent in skin antioxidant, anti-aging, whitening and moisturizing effects.

In order to achieve the above object, the present invention is a skin external preparation composition containing, as an active ingredient, a packaged fermented extract produced by fermenting a natural product by wrapping or covering with a medicinal flower ,
The natural products include beans, bitter rind, mung beans, solitary, bashken, bon bonsai, bonito, soy sauce, mulberry leaves, lotus seeds, gokazuku, tsumerengue, dogbill, dragon gall grass, longan grass, evening primrose, beneficial mother grass, carrot , Chen Chen, Red cabbage, Mongkok, Makiko, Shingoka, Mikoko, Kawamata, Uchiwadokoro, Tianshan Snow Lotus, Aoi, Kusanagi, Seisoushi, Earthen, Kusanem, Genokosho, Red Ginseng, and One or more selected from the group consisting of Menamomi,
The medicinal flower provides a skin external preparation composition that is at least one selected from the group consisting of chrysanthemums, gold and silver flowers, kiso flowers, kobushi, and lotus flowers .

The present invention also includes a step of boiling or steaming the washed and dried natural product for 30 minutes to 2 hours,
Cooling the boiled or steamed natural product at room temperature for 30 minutes to 1 hour;
Wrapping or covering the cooled natural product with medicinal flowers, putting it in an unglazed pottery, and fermenting at room temperature in the shade for 4-7 days,
And a step for removing medicinal flowers from the fermented natural product and extracting the medicinal flowers.

  The medicinal flower wrapping fermented extract according to the present invention exhibits superior skin efficacy in anti-oxidation, anti-aging, whitening, moisturizing, etc. compared to natural product extract before fermentation and general fermented natural product extract. The wrapped fermented extract thus obtained can be used in various fields such as cosmetics and pharmaceuticals.

  The present invention provides a skin external preparation composition containing a packaged fermented extract produced by fermenting natural products by wrapping or covering them with medicinal flowers.

The present invention also includes a step of boiling or steaming the washed and dried natural product for 30 minutes to 2 hours,
Cooling the boiled or steamed natural product at room temperature for 30 minutes to 1 hour;
Wrapping or covering the cooled natural product with medicinal flowers, putting it in an unglazed pottery, and fermenting at room temperature in the shade for 4-7 days,
And a step for removing medicinal flowers from the fermented natural product and extracting the medicinal flowers.

Hereinafter, the present invention will be described in more detail.
The medicinal flowers that can be used in the present invention include kuzuhana, chrysanthemum, chicken crown flowers, subsidized winter flowers, spikelets, gold and silver flowers, peach flowers, scented flowers, spikelets, bud flowers, jungle flowers, bud flowers, pine flowers, It is at least one selected from the group consisting of sarcophagus, whirling flower, whirling flower, pine flower, kobushi, lotus flower, camellia flower, hollyhock, camellia flower, scarlet yellow and red and blue flower.

  Kuzuhana means the flower of Kuzune. Kuzuka is used for headaches caused by overdose, fever, and stuffy and clogged breasts, dry mouth, anorexia, abdominal distension, and vomiting.

  Chrysanthemum is a dried flower of sweet chrysanthemum or white chrysanthemum. Gan chrysanthemum has an effect on suffocating symptoms such as pneumonia, bronchitis, headache, stiff shoulders and high blood pressure in the chest. Used for liver function and hyperemia, menstrual irregularities and skin problems such as acne.

  The crown flower is a flower of Celosia cristata L., an annual herb belonging to the Amaranthaceae family. The flowers bloom in red, yellow and white from July to August and are actually oval and contain 3 to 5 black seeds. Chicken crown flowers are used for the purpose of hemostasis for symptoms such as menorrhagia, uterine bleeding, and vomiting, including ophthalmic diseases.

  The subsection Fuyuhana refers to the bud of Tussilago farfara L .. Subsection Fuyuhana is used for antitussive, expectorant, sputum and pulmonary tuberculosis, lung abscess, and for exogenous cough, asthma and upper respiratory tract infection. Pharmacological effects have been reported to be effective for antitussives, respiratory excitement and anxiety, vasoconstriction, acute bronchitis in children, bronchial asthma, and sore throat by increasing respiratory secretions.

  Yuka refers to a bud of Sophora japonica L .. Reika is used as a hemostatic agent to stop constipation, collapsing, etc., and hepatic hyperemia, vaginal bleeding, uterine bleeding, nasal bleeding, bloody stool, and blood. It is also effective for high blood pressure, headache, dizziness, arteriosclerosis, middle wind, cerebral hemoptysis, and dyspnea. As pharmacological actions, hemostatic action, decreased capillary permeability, blood pressure lowering, cholesterol lowering, anticonvulsant, anti-ulcer, anti-radioactive action, frostbite treatment, and laxative action have been reported.

  Gold and silver flowers refer to Lonicera japonica Thunberg or buds of related plants. Gold and silver blossoms are used when the fever is lowered and the chest is stuffy and thirsty, and is good for inflammation, expelling swelling, skin poisoning, organ inflammation, and pus. It is also used for dysentery, skin tissue injury due to heat poison, mastitis, etc. It is applied to colitis, gastric ulcer, cystitis, sore throat, tonsillitis, bronchitis, conjunctivitis and the like, high fever due to epidemic parotitis, purulent infection, etc. As for the pharmacological action, antibacterial action, anti-inflammatory action, antipyretic action, increase in leukocyte phagocytosis, central nervous excitability, serum cholesterol lowering, ulcer prevention effect, etc. have been reported.

  Peach blossom refers to the flower of Prunus persica (L.) Batsch or P. davidiana (Carr.) Fr. It is effective for water use, vitality, and bowel movements, and treats edema, beriberi, urinary stool difficulties, and menstrual disorders.

  A fragrant flower is a flower of the perennial herbaceous plant Hierochloe Odorata, which belongs to the department of the genus. Used to stop vomiting and nosebleed, and to stop blood and pain on pressure sores and metal wounds.

  The camellia flower is a perennial herbaceous plant, Imperata cylindrica var. Major (Nees) C. E. Hubb. It has the effects of blood feeding, constant pain, hemostasis, and fever. It is used to treat blood pressure, nasal bleeding, and pressure ulcers when injured by metal.

  Kiso flower is the flower of Hibiscus syriacus, a deciduous shrub of the mallow family. Kiso flower treats intestinal bleeding, dysentery, white belt, skin diseases. As a component, saponarin (saponarin) is contained, and it has been reported that it has an antitussive action as a pharmacological action.

  Mitsumonka refers to the Buddleja officinalis Maximowicz bud. The appearance is irregularly conical and the outer surface is covered with yellow and soft hair. The bud is short and soft. Zhong Meng Flower is used for hepatic fever, hyperemia, pain, symptoms of tearing away from sunlight, cataracts and glaucoma. It also treats children's pressure ulcers, measles and gonorrhea poisons that have entered the eye. As main components, components such as acacin and acacetin have been reported.

  The flower is a flower of Saposhnikovia divaricate S. Bow-fu flowers are white, blooming in a double inflorescence at the end of the main stem and the end of the branch, and about 5 small umbrellas are split at the end of the total umbrella, each with many small flowers. The flowering period is from July to August. Bowfu flowers are used for treating abdominal pain, extremity arrest, and fracture pain.

  The narcissus flower is an annual herbaceous flower of Impatiens balsamina L .. A variety of anthocyanins are contained in bud flowers, and kaempferol, quercetin and naphthoquinone are contained therein. As a pharmacological action, it is known to have an inhibitory action against Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi and Shigella. It is mainly used for the treatment of urination difficulties, postpartum hemoptysis, bruises, heels, pressure sores, etc.

  The stalagmite is a flower of Punica granatum L. Stone flower stops bleeding from nasal bleeding, otitis media, and stab wounds, and is used for bleeding, irregular illness, burns, and toothache.

  The whirling flower is a flower of Inula Britannica var. Japonica (Thunb.) Franch. & Sav. Whirling flowers have a unique odor, taste bitter, and have a slightly warm character. Circulatory flowers are used to circulate and dissipate frustration, used for sputum, coughing, hiccups, sneezing, asthma, chronic bronchitis, acute pleurisy, dyspnea as if the chest is always full, nausea, breast cancer, Used for milk folds. As pharmacological actions, bronchial anticonvulsant action, diuretic action and the like have been reported.

  The whirling flower is a flower of the periwinkle plant of the family Convolvulaceae (Calystegia japonica C.). The flowers bloom from June to August and are pale red. Used to make up for, remove freckles on face and improve complexion.

  The pine flower is a flower of Pinus densiflora S. et Z .. The male flowers are blossomed under a new branch of a male and female pine tree and are oval and brown. One to three female flowers are blooming upward, are about 6 mm in length, and are oval. The pollen is characterized by yellow light and a sweet scent. It is mainly used when making and eating tea foods and honey water.

  Kobushi refers to a bud of the magnolia family Magnolia denudate Desrousseaux or its genus. Kobushi treats cold nose and nasal congestion from the wind, purulent symptoms, runny nose, unscented symptoms, headache and poor concentration, chills, fever, general pain, and many Effective for coughing. As a pharmacological action, an astringent action, a capillary dilation action, an anti-inflammatory action, a blood pressure lowering action, an analgesic, a sedative action, a skin fungus and a staphylococcal inhibitory action have been reported.

  The lotus flower is a flower of the water lily family (Nymphaea nelumbo L.). The lotus component contains various flavonoids such as quercetin, reteolin, isoquercetin, kaempferol and the like. Lotus has an effect of live blood, hemostasis, and wetness, and is used to treat blood bruising and chicken pox.

  Aoihana refers to a bud of the Daphne genkwa Siebold et Zuccarini. Reika is used for edema, lowering the water remaining in asthma, cough, and flank. It is also used for symptoms of abdominal distension, swelling, head rash, urination and stool discontinuity. Pharmacological effects have been reported to increase urine volume, suppress intestinal and uterine motility, and insecticidal action.

  The hollyhock is the flower of the mallow (Althaea rosea Cavanil) in Korea. Appearance is yellow or light brown, with 5 complete petals. The hollyhock is used for white belt, lower abdominal coldness, urinary stool passage, vomiting, uterine bleeding, burns, redness of the nose. As a pharmacological action, malaria has been reported to be effective.

Spider flowers are allium fistulosum L. flowers. Reika is used to treat abdominal sting with splenic heartache.
Scarlet yellow is a flower of Typha orientalis C. Presl. The pollen reduces blood fever, has convergence, hemostasis, is used for hemoptysis, vomiting, nosebleed, urinary bleeding, uterine bleeding, improving blood circulation, abdominal pain caused by blood coagulating in the chest, Used for postpartum hemoptysis and menstrual pain. As pharmacological actions, uterine excitement, blood pressure lowering, antispasmodation, shortening of blood coagulation time, growth inhibition of Mycobacterium tuberculosis, cholesterol lowering action, etc. have been reported.

  Red and blue flowers are flowers of the family Asteraceae (Carthamus tinctorius L.). As a pharmacological action, it is known that the contraction action of the uterus, the intestinal tract and the like is strengthened through smooth muscle excitement, and it is effective for blood pressure lowering, blood coagulation antagonism, bruise, sprain injury, tendonitis and the like. Red and blue flowers have the effects of vitality, pain, morphogenesis, and pain relief and treat amenorrhea, dystocia, stillbirth, phlebotomy pain, atheroma and bruises.

  Natural products that can be used in the present invention are beans, coconut meat, kudzu root, katsu active, sweet chrysanthemum, dry yellow, dry lacquer, licorice, dried melon, zeushiko, deciko, bitter rind, kakimoto, bitter, murresuzume, caronine , Eggplant, cuckoo, persimmon, tachibana bark, gold and silver flowers, buns of grass, chrysanthemum, bellflower, harrigwa, child, south star, deer horn glue, mung bean, deer crab, rhododendron, turnip, touki, buntan fruit, black thistle, soybean yellow Roll, cannabis, mushroom, large green grass, large yellow, peach seed, self-existence, cordyceps, tochu, mao, bashken, variegated grass, vine, malt, bakumon winter, kiso, kidori, incense, buoy, mushroom, Light load, Bow-fu, Semi-summer, Chinese cabbage, White cabbage, Bald eagle, White rose, White and white, Sandalwood, White birch, White birch, White eggplant, Shishijin, White flower serpentine, White birch, Japanese cypress, White birch, White bonsai, Salmon, large belly skin, tendon, leek, Kitashibahu, borneol, tang, sansang, sansang, hawthorn, yam, yamayaku, soy sauce, yam Semi-summer, Okera, Mulberry parasitism, Mulberry white bark, Tsuneyama, Mulberry leaf, Soshiko, Ginger, Ishizuchi, Sentsukakusa, Yukimi grass, Spicy, Soba, Pine, Ryukyu Oubai, Komika incense, Zushi palm seed, Continuation, matsutake mushrooms, ramie, shirahiko, Shinkyoku, Yakanmon, Tsurudokudami, fish licorice, ream, lotus, lotus seeds, litchi, reiharu flower, ganoderma, bun, gokahide, gomiko, quintuple, wuluo, Glaze, tamamai-don, tamatake, tsumerengue, raspberry, dragon gall, longan, beef-knee, distant, spider, evening primrose, threatening sensation, ▲ 楡 ▼ (elm) root bark, rape blossoms, meat candy, ginbaiko , Mutton, Yokuinin, profit mother grass, masochist, carrot, 茵 蒿 蒿, Japanese Toki, Hitsubahagi, Japanese cucumber, Zion, purple, glaze, garlic, elder, red potato, red garlic, red cabbage, red candy , Front cucumber, rowan, clove, horned horn, horned horn, crispy, strawberry, Persimmon, earth bone skin, persimmon, acquaintance mother, earthen skin, fruit seed, earthen earth, earth yellow, saws, Shingoka skin, small citrus grass, Chen skin, car front child, ear ear, senkyu, hempen, heaven gate Winter, Kawamata, Semeuzu, Millennials, Prickly Pears, Tenzan Snow Lotus, Amakusa, Amakusa, Grass, Grass, Grass, Lion, Seisoushi, Hollyhock, Agarica, Sawaran, Heramodaka, Karachi, Earthenware, Silkworm, Soil Senkyu, Tsutsukusa, Sasame, Satsuma Beans, Sakai Koei, Sui Huang, Oribukuro Orchid, Whats Nada, Kusanem, Anjin, Sunflower, Sunflower, Kosuke, Kouju, Koso, Koso, Gensen, Genkosho, Genkoko, Sasa, Sesame Seed, It consists of cucumbers, pumpkins, safflower, red ginseng, kelp tea, red clover, safflower, flower coat, dragonfly, jaundice, huangren, miyako yuri, dankobai, jaundice, kobetsu, black check cow and menamomi One or more selected from the group.

  Beans are also called soybeans. It is widely cultivated as an edible crop, and is actually fruit, striped flat oval, containing 1 to 7 seeds. When fully ripe, the pods fray and the seeds are scattered. Seeds vary in variety, such as round shape and flat and round shape, depending on the variety, and the sizes are also very diverse. There are various seed colors such as yellow, black, light brown, and green.

Eggplant meat is a fruit pulp that has been dried by removing seeds from the mature fruit of eggplant (Terminalia chebula Retzius), and is used for the treatment of diarrhea, dysentery, subaid, anal prolapse and the like.
Kakkon refers to the roots of kuzu turmeric, which is used to reduce fever, sweat, dry mouth, headache, back pain, and neck / shoulder / back stiffness.
Acupuncture is a biennial or perennial grass of the celery family that is actually oval, and roots similar to bellflower are used as antipyretic and analgesic in Chinese medicine.
Gan chrysanthemum is a perennial grass that grows mainly in the mountains. In October, the flowers are dried and drunk in liquor, and the young leaves are used as green cocoons. The flower has a pungent scent and is cultivated for ornamental purposes. In Chinese medicine, prescribed for the treatment of hot cold, pneumonia, bronchitis, headache, gastritis, vaginitis, swelling, etc.
Dry ground yellow refers to the roots of freshly dried ground yellow, which lowers the heat and is used as a medicine for blood replacement and hemostasis.

Lacquer lacquer is made by collecting and drying lacquered lacquer and is used for menstrual disorders, hemoptysis, helminthiasis and the like.
Licorice is a medicinal plant with roots that are sweet and used as sweeteners and herbal medicines.
Psoriasis is a term used to describe dried ginger in Chinese medicine and is used to treat gastric cold, vomiting, and diarrhea.
Tickling refers to the morning glory seeds that are bitter in taste, cold in nature, and smooth urine. Used for the treatment of constipation, edema, shakuju, and back pain.
Seiriko says the seeds of Mameshina's annual fresh-meat tea. Actually, it bends like a bow and ties long sachets, but the seed in it is Akiko.

An agony skin refers to the roots and skins of oysters. Used as an anthelmintic agent.
Enomoto is a perennial grass of the Apiaceae family that produces oval fruits and uses medicinal roots. In traditional Chinese medicine, what was dug and dried in autumn is called Enomoto, and it is prescribed for headache, joint pain, toothache, abdominal pain, diarrhea, eczema and so on.
Bitter is a legume perennial and its roots are medicinal. Bitterns are mainly used for jaundice, malaria, melena, etc. because they have roots, have a bitter taste and are cold in nature.
Muresuzume is a deciduous deciduous shrub of legumes that is cultivated for ornamental purposes and distributed in places such as Korea and China.
Caronin is a perennial vine species of the Cucurbitaceae family and is used to smooth milk and urine and to relieve swelling.

Eggplant is the fruit of an oak tree and is used as an antipyretic and tonic.
Cuckoo is a perennial grass of Lamiaceae and is used for treatment of digestive disorders and inflammation.
Acupuncture is a perennial grass family that is used to treat menstrual cramps and melena.
Tachibana bark is a citrus peel that is warm in nature and helps digestion, and has medicinal properties such as cough, diarrhea, and shakuju.
The gold and silver flowers are the flowers of Shinobazuka, which lowers the heat and dissolves the poison, and is used for cocoons.

Kujukusa is a perennial grass that belongs to the Asteraceae family. Herbal medicine Kujukusa is a dried stem and leaves. In Kampo and the private sector, the whole flowered grass is prescribed for folding screens, gynecological diseases, and gastromania.
Chrysanthemums are perennial grasses belonging to the family Asteraceae, and flowers mainly fall in autumn, but the shapes and colors of the flowers vary.
Kikyo is a perennial grass of the Campanula family, whose roots are edible or used as a medicinal material for expectoration and antitussive.
Hariguwa is a deciduous tree of the mulberry family and is known to be effective in treating tinnitus symptoms.
Saiko refers to the seeds of the radish or family of the genus Aplanidae. Used to treat meals or sputum.

The southern star is a perennial grass of the taro family. Used for the treatment of sputum and cough, medium wind, sputum.
Deer antler glue is a medicine made like a paste by boiling the deer antler. It has the effects of supplementation, hemostasis, and pregnancy, and is used for low back pain, hemorrhoids, and under the belt.
Mung beans are used to treat skin diseases in the private sector and have antipyretic and detoxifying effects.
Deer cocoon is a newly developed deer's soft antlers, used to supplement cheerfulness and strengthen muscles.
Hishimi is a rhinoceros fruit of Roshishina's annual grass and is edible.

Turnip is a greenish yellow vegetable belonging to the family Aplanidae and contains a lot of vitamin components. Following the effects of vitamin A, the content of carotene is twice that of spinach, and if you eat 100g of vitamin raw, it is abundant enough to meet 80% of the daily requirement, and rich in iron and calcium. Contained.
Toki is the root of Toki, a perennial grass of the Apiaceae family. Mainly has anti-inflammatory and analgesic effects.
Buntan fruit is an evergreen sub-tree, and is actually used for the prevention and treatment of colds and for the treatment of liver diseases.
Noazami is a perennial grass of the family Asteraceae and is used as a hemostatic agent.
Soybean yellow roll refers to germinated beans of Glycine max Merrill. It is used for limb paralysis due to moisture in the summer, symptom of limb dragging, swelling due to moisture retention, and symptoms of low urine volume. Also used to reduce heat from colds and sweat.

Cannabis is an annual plant of the dicotyledonous family Lamiaceae, and the seeds and leaves are highly toxic, but the leaves are used as asthma tobacco.
Kiso means jujube, which is not only eaten raw, but dried after being collected and used as dried fruit for confectionery, cooking and medicinal purposes. In traditional Chinese medicine, it is used as a diuretic, tonic, and relaxation agent. Is done.
Daegusa is a whole plant of the foxtail family Hygrophila salicifolia (Vahl) NeeS. And is known to treat epidemic fever, jaundice, relieve wrinkles, relieve cough, and treat vomiting. (Chinese Great Dictionary). Contains about 25% oil and trace amounts of alkaloids, calcium phosphate and calcium chloride.
Daihuang is a perennial plant of the family Tadeceae, and its roots are medicinal, but it has a bitter taste and is used for inability to pass urine, wows, sleeping words, shakuju, and phlebotomy.
Taojin refers to kidney in the peach seed (relatively large granules in the seed nucleus) and is mainly used as a herbal medicine. It is used for medicinal purposes such as cough, constipation, and hemoptysis.

Independence is often used for the treatment of muscle pain, lower body paralysis, headaches, and mid-wind insufficiency.
Cordyceps is a collective term for moths of the Cordyceps family, meaning that what was insects in the winter turns into grass in the summer. Effective in enhancing immunity, anticancer, and anti-aging.
Tochu is a deciduous tree from Tochushina. In Kampo, the bark is used as a supplement and tonic, to make the cerebrum healthy, and to treat lung and knee pain and insomnia. In the private sector, decoction of leaves is used for neuralgia and high blood pressure, and it is also taken as tea.
Mao is an evergreen shrub of the magnolia magno family, which has the effects of sweating, antipyretic, antitussive and diuretics and is used to treat fever and asthma.
Bashken is used as feed and medicine. This material is soft but has a unique odor, is mucous, has a salty taste and is cold in nature. It has antipyretic, detoxifying, and hemostatic effects, and is used for bacterial dysentery, swelling, hemorrhoids, cervical lymphadenitis, eczema, subbing, uterine bleeding, and difficulty in urinating. As pharmacological actions, antibacterial action, intestinal fistula action by enhancing uterine smooth muscle contraction force, diuretic action, etc. have been reported.

Manchuria is an evergreen shrub belonging to the dicotyledon azalea family, and is used as a diuretic and tonic.
Ginseng is a conflicting perennial grass of the dicotyledonous Campanula family Campanulaceae and is used as an expectorant.
Malt is a grain of wheat germinated by allowing moisture, temperature, and oxygen to act on shelled wheat, and is used as a raw material for beer brewing, and is often used for preparing microorganism incubators. It contains saccharides such as starch and vitamins, has strong amylase, and is used as a nutrient, digestive (such as diastase), sometimes livestock feed, and raw material for producing maltose.
Mumon winter is an evergreen of the monocotyledonous lily family and is used as an anti-inflammatory, tonic, antitussive, expectorant and cardiotonic agent.
Kiso is a medicinal product of Kiso / Karashi fruit, with a sour taste and warm nature. It is used for muscle flexion and extension disorder, benign disease and vomiting diarrhea.

Kitsu is a stalk of akebi (Akebia quinata Decaisne) or other related genera, and is made by removing the skin and cutting it sideways. Ascites is filled with pyelonephritis, cystitis, and urethritis due to the wet heat of the bladder. Sometimes used for paralytic pain when heart rash causes rash in mouth, heartburn, urine is red.
Incense is a perennial grass of the dicotyledonous Campanula family, and is used as a sweat, diuretic and expectorant and has an anthelmintic component.
The buoy is a medicine obtained by drying the ripe fruit of Ulmus macrocarpa belonging to the family Elmidae, and is also called “Mu-go”, “Mui-in”, “U-mui” in Korean. It is also used for hemorrhoids, hemorrhoids, and pressure sores.
Makiontan is a medicine made from the root bark of peony. When menstruation due to blood fever, menstrual pain, bruising, bloody symptoms, nosebleeds, spots appearing, bone pain due to fever, increased blood pressure, It is used for exsanguination, bruising, anti-inflammatory analgesia, swelling treatment, early appendicitis, etc., to eliminate chest discomfort. In addition, analgesic, sedative, antipyretic, anticonvulsant, anti-inflammatory, antithrombotic, antiallergic, gastric secretion suppression, uterine mucosal hyperemia, antibacterial action and the like have been reported as pharmacological actions.
Hikaru is a perennial perennial plant of the dicotyledonous plant Lamiaceae, and menthol is used as a cleansing agent and fragrance for toothpaste, jam, candy, cosmetics, etc. .

Bofu is a medicine made using the roots and rhizomes of the safflower (Saposhnikovia divaricate Schiskin), and is very important in treating wind diseases. It is effective for all wind illnesses such as external headache, chills, fever, general pain, and sore throat.
Half-summer is a perennial grass of the taro family, which is toxic to bulbs. In Kampo, it has effects such as expectoration and coughing, and is used for vomiting, diarrhea, and vomiting during pregnancy.
Chinese cabbage is a biennial grass of the poppy family Apranidae. 100 g of Chinese cabbage contains vitamin A 33 IU, carotene 100 IU, vitamin B ₁ 0.05 mg, vitamin B 2 0.05 mg, nicotinic acid 0.5 mg, vitamin C 40 mg. Yes. Vitamin A does not exist in the white part of soft white, and there are many in the blue part.
Hakutsuna refers to the above-ground part of the poppy family Chelidonium majus Linne. As pharmacological actions, anticonvulsant, intestinal peristalsis and salivary secretion promotion, antitumor, hepatitis, antibacterial action were reported.
The bald eagle refers to the roots of the genus Pulsatilla koreana Nakai or related plants in Korea. Used for damp dysentery, amoebic dysentery, cervical lymphadenitis, hemorrhoid hemorrhage.

White rose is a medicinal material made from the roots of Cynanchum atratum Bunge or its genus plant, which lowers the heat of blood and consumes blood and blood from the later stages of heat disease and postpartum. It has a slight fever inside, and heales sickness, and is used for fever, cough due to lung fever, diuresis, swelling, scab, sore throat, and snake bite.
Hakuo is a dried medicine of purple orchid tubers of the Orchidaceae, and its efficacy is a hemostatic used for hemoptysis by lung fever and gastric fever. It is powdered for trauma and applied to the affected area. It is used for surgical diseases such as swelling, and acts to create granulation tissue. As pharmacological effects, local hemostasis, stomach and duodenal treatment, suppression, blood pressure increase, and anticancer activity have been reported.
Sandalwood is an evergreen persimmon tree of the sandalwood family, and the inside of the tree is light yellow and has a good scent. It is used in incense burners, medicines, and crafts.
Birch is a word that refers to roots of moths in Chinese medicine and is used to treat pressure sores and burns.
White shark is a dried shark's mycorrhiza, has a sweet and thin taste, has a mild and complementary effect, has a diuretic effect, but is not strong. It has been used as a tonic since ancient times, acting on the lungs, spleen, heart, nerves, and bladder, supplementing the spleen, relieving wrinkles, and stabilizing the mind. According to the results of pharmacological experiments, it is known to have a diuretic action, an action to lower blood sugar level, a sedative action, and the like, and is also known to have an immune revival action.

Shiratsuki has a strong poison in the roots, but is used as an antispasmodic and analgesic in Chinese medicine.
Yuzujin is the seed of Yuzujin. It stabilizes the mind and body and lubricates the intestines, and is used for startle, palpitation, sweating and constipation.
White flower serpentine grass refers to the whole plant of Oldenlandia diffusa (Willd.) Roxburgh. Used for cough due to lung fever, tonsillitis, sore throat, used for appendicitis, pelvicitis, jaundice hepatitis, dysentery, and also has a detoxifying effect on swelling and snake venom.
Birch is a perennial grass of the family Mushrooms, and its roots are used for analgesia, antispasm, and gynecological diseases.
Juniper refers to the root of the armored bush, used for cold headaches, back pain, nasal polyps, etc., and also used as a surgical agent for swelling.

Egret is a medicine that has been dried by removing rhizome or pericyle of asteraceae of the asteraceae or birch, with weak splenic stomach function, small eating, malaise, when the complexion is yellow or stool is loose It is good for diarrhea, and when the whole body is swollen due to water retention and is difficult to digest, it helps to drain water. It is also used for coughing, transparent sputum, etc., and for colds with gastrointestinal disorders and limb pain.
Covered bonsai is a medicinal product made from the unripe fruit of a covered bonsai strawberry from the Rosaceae family. It has no odor, tastes sour and sweet, and is warm. Improves the function of the kidney, is used for sperm, dream, etc., is used to weaken vision, lighten the body and blacken the hair. It also makes the skin soft and beautiful. As a pharmacological action, an anti-inflammatory action, an antioxidant action, and an anti-Helicobacter pylori action have been reported.
The moth is a basidiomycete, Sarnocosiaceae, and the white one is the white moth and the red one is the red moth. All are effective for tonicity, diuresis, sedation, etc. as Kampo medicines, and are used for kidney disease, cystitis, and urethritis.
The large abdominal skin is a medicine made from the ripe pericarp of areca (Areca catechu L.). It is used for edema and bloating and is effective in improving large and small stools. Effects have been reported.
Tsutsumi is a tuber of aconit belonging to the family Mushrooms, and is used in Kampo with warm sensation, intensification, analgesic, diuretics, etc. with Keishi, cocoon, licorice, etc., but never alone. In addition to recovering from the extreme decline of budding metabolic function, it is used for cold, chills, paralysis, pain, neuralgia, and rheumatoid arthritis.

The leek is a perennial grass of the lily family, the bulb has a short rhizome at the bottom, and black-yellow fibers on the outside. Bulbs are used for healthy stomachs, burns, etc., and thin plants are edible. The seed is used as a urinary medicinal material in Chinese medicine, called rapeseed.
Kita-Saihu contains saponin and fatty oil in the roots, and is used as a medicinal material for antipyretic, analgesic, tonic, respiratory, fire extinguisher and cardiovascular diseases in Kampo.
Borneol refers to a crystal obtained from a dragon brain tree. It is aromatic and is used for the treatment of mental confusion and sore throat due to medium wind, hemorrhoids, and fever.
Entanglement refers to the reticulated fibers and vascular bundles of the fruit of the Luffa cylindrical Roemer. It has been reported that edema of air-humid arthritis, anti-inflammatory effect on redness, analgesia, and suppression of skin bacterial infections.
Shasan is a medicinal material made in the roots of Adenophora triphylla var. Japonica Hara or a plant belonging to the same genus (Korea), and reports on expectorant, antibacterial, hemolytic, and cardiotonic effects as pharmacological effects Has been.

Sansang is a kind of medicinal ginseng that grows naturally in the deep mountains. Its taste is sweet and slightly bitter, and its nature is a little warm. It enters the spleen and lungs, and has the effect of supplementing energy.
Hawthorn is a medicinal product obtained by drying ripe berries of the Rosaceae (Crataegus pinnatifida Bunge var. Typica Schneider) and its genus plants, and has been reported to have cardiotonic action, blood circulation improving action, and blood pressure lowering action.
The yam is the fruit of the yam, which is a deciduous oak tree of the dogwood family. The pulp contains glycosides such as cornin, moroniside, loganin, tannin, saponin, and organic acids such as succinic acid, malic acid, and tartaric acid. In addition, vitamin A and a large amount of sugar are also included. In traditional Chinese medicine, pulp has been used for medicinal purposes, but it is used as a medicine for headaches, tinnitus, cough disease, antipyretic, menorrhagia, folk remedies such as cold sweat and nocturnal enuresis.
Yamayaku is a tuberous root of the genus Disocorea japonica or yam (Disocorea batatas) belonging to the family Dioscoreaceae, and has the effect of making the spleen and lungs healthy.
Acid soy sauce is a medicine made from soy bean seeds and is used for irritability, insomnia, forgetfulness, cold sweat, etc., making the spleen and stomach healthy and effective for anemia. As for the pharmacological action, sedation, hypnosis, hypotension, analgesia, hypothermia action, antioxidant action, immune enhancement action, uterine excitement action, etc. have been reported.

Mountain lion is a fruit of a mountain coconut tree and is used as a medicine for antipyretic, hemostatic, diuretic and the like.
The semi-summer is a perennial grass of the dicotyledon, Pepperaceae, which is used when the body is swollen and urinating, and it is also used for beriberi, jaundice, and hepatitis.
Okera is a perennial plant of the dicotyledonous Campanula asteraceae, and uses rhizomes as a medicinal material, but it is effective for sweating, diuresis, analgesia, healthy stomach, etc. Used for colds, etc.
Mulberry parasitism is a medicine made by drying leaves, stems and branches of mistletoe (Loranthus parasticus Merr.) Or mistletoe (Viscum album L. var. Coloratum Ohwi). It has a lowering effect, is used for dizziness due to high blood pressure, supplements the liver and kidneys, makes bones and muscles healthy, and is used for fetal movement anxiety.

Mulberry white skin is a medicine made from the root bark of mulberry or the same genus plant. Mulberry white skin treats cough and asthma due to lung fever and has a diuretic action. It is used for acute pyelonephritis and frail edema, has a blood pressure lowering effect, and is also used for nosebleeds and phlebotomy. It is also used for epidemic hepatitis. As for the pharmacological action, coughing, diuresis, hypotension, sedation, analgesia, antipyretic, antispasmodic, antibacterial action, etc. have been reported.
Tsuneyama is a dicotyledonous deciduous shrub of the dicotyledonous plant, which uses roots as a medicinal material called odor goat, but treats cough, fever, and sore throat due to cold, and it is known as damp arthritis, dysentery, swelling, malaria, etc. Is effective.
Mulberry leaves are dried medicine from the leaves of the mulberry family (Morus alba L.) or related plants of the same genus, and are used for fever, headache, eye redness, cough, dry mouth, skin urticaria, etc. The
Aiko is also called red bean. The pod has a highly toxic abrin, so it is used as an arrow poison, and the leaves contain glycirrhizin, which is sweet like licorice and decocted to make a drink.

Ginger is dried and pulverized, used as a spice for bread, sweets, curry, sauce, pickles, etc., peeled and boiled, then dipped in syrup, ginger tea and ginger liquor, etc. Or make. In traditional Chinese medicine, dried rhizomes are used as a medicine called psoriasis, which is effective against indigestion, vomiting and diarrhea, promotes blood circulation, and has anti-inflammatory and analgesic effects.
The sarcophagus is a perennial plant of the monocotyledonous aratomaceae araceae, and uses the rhizome as an analgesic, sedative, and stomachic agent, and takes it in the bath in the private sector.
Sentsukakusa is a perennial plant belonging to the family Rosaceae, and is used as a therapeutic agent for hemostasis, astringent action, diarrhea, uterine bleeding, detoxification, vomiting, stool bleeding, atheroma, and cancer.
Yukimiso is a Lamiaceae plant that is rooted in Salvia plebeian R. Br. And tastes bitter and spicy. It is also known to be effective in relieving swelling and used to treat vomiting, nasal bleeding, bee leakage, bruises, and venom.
Spicy is a medicine made by drying the roots of the perennial plants Usubasaicin and Keirinsaicin, which are used when headache, nasal congestion, fever, hemorrhoids, cough due to cold or cold . It can also be used for laryngitis, rhinitis, bronchitis.

Soba is an annual plant of Lamiaceae, with leaves and stems used as medicinal materials and young leaves and seeds edible.
Pine is an evergreen coniferous tree of the pine family, the leaves are used as a source of beriberi, indigestion or tonic, the flowers are dysentery, and the eyelashes are used as a salve.
Ryukyu Oubai is used for wound healing using the roots of Jasminum floridum Bge.
Ogura is an annual plant of the celery family, also known as Dill. Flowers, leaves, stems and seeds are used as herbs because they have a unique scent throughout the plant. The seeds excel in digestion, wind drive, sedation, and hypnosis, are good for removing bad breath and preventing arteriosclerosis, and can sleep well if used as a pillow.
The secondary coconut seed is a seed of the secondary handgrip, which is a medicinal plant, and the residue obtained by extracting the oil is used for diuretics, laxatives, edema, ascites, food poisoning and the like. The coconut seeds are very toxic and must be taken care of.
Suspension is a perennial grass of the dicotyledonous Lamiaceae, with thick roots used for cuts and gynecological diseases.

Shochu is a typical edible mushroom that has a unique fragrance and taste that occurs on the land of pine forests. It is edible as a high-grade koji and has an anticancer effect.
Hemp is a perennial grass that belongs to the family Mushrooms and uses the roots as an antipyretic and antidote in traditional Chinese medicine. It has been reported that if used with a cold and high heat, the heat falls while sweating.
Shibahu is a dicotyledonous, perennial plant belonging to the Umbrella family, with saponins and fatty oils in the roots, and is used for herbal medicine, antipyretic, analgesic, tonic, respiratory, fire extinguisher, and circulation. Used as a medicinal material for organ diseases.
A divine song usually refers to a mixture of six ingredients. The function of the fire extinguisher is made healthy, and it has the action of helping digestion and the action of calming the stomach. It is effective when eating, when the chest is stuffy and heavy, when vomiting and diarrhea, and when the stomach hurts due to postpartum hemoptysis. As a result of pharmacological experiments, it has been reported that there is a healthy stomach effect.

Yakanmon is a half-shrub of the dicotyledonous rosaceae family, and is used in places where cheerfulness, scabies, premature ejaculation, cough, whooping cough, and snake bites. As pharmacological actions, antitussive action, expectorant action, flat asthma action, action on uterus, antibacterial action, etc. have been reported.
Tsurudukudami refers to the stems of the neck of the dicotyledonous genus Perennial, which is effective against coughing, expectoration and arthritis.
Fish salmon grass refers to the above-ground part of the flowering season of the coral summer fish. Fish eelgrass has excellent antipyretic and drainage effects, and is used for pneumonia, acute chronic bronchitis, vaginitis, urinary tract infections, swelling, high fever, difficulty in urination Used when As pharmacological actions, antibacterial action, immune enhancing action, anti-inflammatory action, diuretic action, and antitussive action have been reported.
Renren refers to the forsythia or forsythia of the oleaceae family. Because liaison lowers fever and detoxifies, it lowers the fever of the heart in the early stages of heat sickness and is used for high fever and mental confusion, used for swelling, rash, appendicitis, lung abscess, lymphadenitis, sore throat, etc. Has diuretic and anti-inflammatory effects. As pharmacological actions, antibacterial action, anti-inflammatory action, blood pressure lowering, hemostatic action, liver treatment action, fever, antiemetic, diuretic action have been reported.

Renko says lotus fruit and is used for gynecological diseases.
Lotus seeds are lotus seeds, which are medicinal materials that have been peeled and dried. It is a supplementary medicine that has been widely used for a long time because it helps the spleen and stomach, strengthens the spirit and mood, and makes it lighter if taken for a long time, prevents aging, does not bind, and has a long life. As a pharmacological action, an inhibitory action against nasal cavity cancer and throat cancer has been reported.
Ganoderma is native to southern China and is often cultivated as a fruit tree. The pulp is sour and sweet, has a unique scent and is eaten raw.
Reunion flowers are also called poppy flowers. In the private sector, poppy seeds and plants were separated and used for emergency diseases. If you smoke opium together with cigarettes, you will get drunk and feel ugly, if you become addictive, you will be addicted to it, and if it is severe, you will die. Seeds contain 45-50% fat, are used for food or industry, and have no drunkenness.
Ganoderma is a semi-circular, elongate or fan-shaped cocoon. In Kampo, it has effects such as tonicity, antitussive, and antitumor, and it is used for nervous breakdown, heart disease, hypertension, and various carcinomas.

Shantou is a tuber of aconit belonging to the family Mushrooms, and is used in Kampo along with katsushi, cocoon, licorice, etc. as warm excitement, intensification, analgesic, diuretic, and never used alone. In addition to recovering from the extreme decline of budding metabolic function, it is used for cold, chills, paralysis, pain, neuralgia, and rheumatoid arthritis.
Goka-zaka refers to the root, stem and branch skins of the sorghum family or genus plant. Gokahide supplements the liver and kidneys and makes muscles and bones healthy, so it is used for limb paralysis, convulsions, weakness of the lower back and knees, helplessness of the lower limbs, fractures, bruises, edema, etc. . As for pharmacological action, immune enhancement, antioxidant, anti-fatigue, anti-high temperature, anti-stimulatory action, endocrine function regulation, blood pressure regulation, anti-radioactivity and detoxification action have been reported.
Gomiko is a fruit of Gomiko and has five tastes of sweetness, acidity, bitterness, salty taste, and pungent taste. It contains ingredients such as sisandrin, trashin, citral, malic acid, and citric acid, strengthens the heart, lowers blood pressure, increases immunity, and is used as a tonic. Strengthens lung function, has antitussive and expectorant action, and helps treat cough and dry mouth.

The quintuplet is an insect wax made by the aphid Nuldeshiro aphid parasitic on the leaves of the urchinaceae Nurde (pentapod tree), which is empty and has a very sour taste. In Kampo, it has astringent, hemostatic, detoxifying and antibacterial effects and is prescribed for diarrhea, anal prolapse, gastric ulcer, duodenal ulcer, night sweats, spermatozoa, bloody stool, hematuria, stomatitis, etc. The tannin component is contained in an amount of 50 to 60%, and is a raw material for hair dye and ink including the tannin agent.
Kure is a dicotyledonous deciduous tree of the dicotyledonous citrus family and is used in Kampo as a healthy stomach, anthelmintic, detoxifying and diuretic.
The glaze is a dried heavenly glaze tuber, which is used for the treatment of cardio-abdominal pain, beriberi, urinary frequency, etc.
Jade rice is a corn beard in Chinese medicine, diabetes, blood pressure, adult diseases such as cholesterol, diuresis, acute gastritis, nephritis, maternal edema, extinction, antipyretic, hemostasis, stones, pleurisy, ascites, cystitis, urethra Used for inflammation, jaundice, hepatitis, cholangitis, cirrhosis, arthritis, etc.
Jade bamboo is a medicine made by drying the roots of Amadokororo and has the effects of clean heat and nourishment.

Tsumerengue is a dicotyledonous perennial plant belonging to the order of the genus Coleoptera, which is medicinally used as a tonic, and leaves are used as juice, bitten by insects or burned. It has excellent anticancer effects and is effective against antipyretic, hemostasis, hepatitis, eczema, dysentery, malignant tumors, and burns.
Inubouzuki is an annual plant of the dicotyledonous family Coleoptera, which is prescribed for colds, chronic bronchitis, nephritis, hypertension, jaundice, swelling, cancer and the like. In the private sector, raw grass is crushed and applied to illnesses and wounds, or decocted and wiped off.
Dragon gall grass is a perennial grass plant that is used for jaundice, dysentery, genital itch, under the skin, and eczema caused by hepatobiliary fever, and is formulated in limb spasms caused by high fever, cheek pain, headache, mouth pain, eyes Used for symptoms that are congested and cannot be heard well. As a pharmacological action, liver function protection and bile secretion are promoted, and a relatively strong inhibitory action has been reported to Pseudomonas aeruginosa, deformed Neisseria gonorrhoeae, encephalitis bacilli and Staphylococcus aureus.

  Dragon eye meat refers to the temporary seed coat of the long face of the Mukuroji family. The texture is soft, sticky, tastes sweet, has a unique scent, and is used as a snack. Longan is also used when the heart pulsates irregularly, forgetfulness, insomnia, indigestion, and loose stools. It is used when you are sick after illness and cannot control anemia, malaise, or sweat, or when you have edema due to weak blood after birth. Pharmacological actions include scabies suppression, tonic action, antioxidant action, and immune function activation action.

Cow knee refers to the genus Inokozuchi or the root of the cow knee. If raw cows are used, they eliminate blood and swelling, and if they are steamed, they supplement the liver and kidneys and make muscles and skeleton healthy. By removing hemoptysis, it is used for menstrual irregularities, postpartum abdominal pain, replenishing bone fistula, used for arthritis so that it can be well understood, and treat rashes in the mouth and tongue due to stigma. As pharmacological actions, uterine excitability, cholesterol lowering, diuretic, blood glucose lowering, liver function improving and the like have been reported.
Enshi is a perennial grass of the dicotyledonous plant Frosoaceae, and in Chinese medicine, the root is called Zushi, and it is used as an expectorant, tonic, and tonic.
Spider flower is a bud of the genus genus, which lowers the water remaining in the asthma, cough, flank and is used for edema. It is also used for symptoms of abdominal distension, swelling, head rash, urination and stool disability. As pharmacological effects, increased urine output, intestinal and uterine motility suppression, and insecticidal effects have been reported.

Evening primrose uses roots as a medicinal material, but leaves are used in some diseases, and seed oil is used for diabetes in the private sector. Has antipyretic and anti-inflammatory effects, has good roots for colds, sore throat, bronchitis, and dermatitis. Seed oil is effective for diabetes, hypertension, obesity, and suppresses excessive accumulation of lipid components including cholesterol. Therefore, it is applied to hyperlipidemia.
In Chinese medicine, roots are used for gout, arthritis, jaundice, tetanus, etc. in Chinese medicine.
▲ 楡 ▼ Root skin means elm skin, gastric ulcer, duodenal ulcer, small intestine ulcer, large intestine ulcer, edema, edema, gastric cancer, straight cancer, uterine cancer, diuresis, abscess, rhinitis, blister, swelling, Has an effect on swelling.
Rape blossoms consume the oil as edible oil, the second largest after soybean oil, and the oil cake is used as feed and fertilizer. Fat oil separated from seeds is used as an ointment base, a solvent for oily injections, and a machine lubricant.

Meat crab is a medicinal material made from the meat stalks of the genus Oleaceae or other related plants of the same genus, has a unique smell, tastes sweet and sour, salty, slightly bitter, warm in nature . Flesh supplemented with cheerfulness, constipation caused by dryness of the intestines, low back pain due to lack of kidneys, weakness and weakness in the feet, tinnitus, amnesia, sperm, enuresis, infertility, lower belt, cold lower abdomen Used for major bleeding, sweating, and constipation. As pharmacological effects, blood pressure reduction, salivary secretion promotion, respiratory paralysis improvement and the like have been reported.
Ginbaiko refers to the roots of the family Ginkgo biloba, which has no aroma, tingling, sweet taste, and a little cold in nature. Used for yin fever, fever due to overwork, cold sweat, childhood fever, abdominal distension. As for the pharmacological action, prevention of atherosclerosis, prevention of cholesterol accumulation, antipyretic, spermicidal action and the like have been reported.

Lepidoptera is the above-ground part of the barkaceae of the barberry family or other related plants of the same genus. Ryokan is used for erectile dysfunction, sperm, cold uterus, cold limbs, skin paralysis, facial paralysis, forgetfulness, half body insufficiency, hip and knee softness, hypertension, and infant paralysis. Pharmacological effects include semen secretion promotion, blood pressure reduction, coronary blood flow increase, blood glucose lowering, cholesterol lowering, immune function enhancement, antitussive, expectorant, flat belly, sedative action, antibacterial, anti-inflammatory action, chicken femur growth and protein polysaccharide Synthetic activation has been reported.
Yokuinin is a seed from which the seed coat of pigeons of the grass family has been removed. Yokuinin is used for edema, beriberi, spleen stomach weakness and urinary symptoms, diarrhea, loss of appetite, limb paralysis, pain, cramping, muscle pain, antipyretic, drainage, appendicitis. As for the pharmacological action, anticancer, skeletal muscle contraction suppression, intestinal uterine suppression, sedation, analgesia, and antipyretic action have been reported.

The benefit mother grass is a medicinal material that dries the above-ground parts when the flowers of the Lamiaceae beneficial flower grow. Beneficial herbs help remove phlebotomy and help uterine contraction when there is amenorrhea, menstrual pain, postpartum uterine contraction, bleeding and abdominal pain. Use with mild diuretic action when the urine volume is low and does not work well, or when you are swollen, and for eczema, itchiness, or swelling. As pharmacological actions, uterine excitatory action, thrombolytic action, heart and coronary blood flow increasing action, respiratory excitatory action, diuretic action, skin fungal inhibitory action and the like have been reported.
Masutoshi refers to the fruits of Gingidai. Masutomi is used when abdominal bloating due to weakness of the splenic stomach, frequent urination due to weakness of kidney function, symptoms of inability to defecate, pediatric nocturnal urine, uterine bleeding during pregnancy, and spleen convergence function is reduced and a runny nose is produced. As pharmacological actions, increased cardiac contractility, ascites tumor cell inhibition, increased ileal contractility, and the like have been reported.

Ginseng is a perennial grass of the dicotyledonous umbrella-shaped asteraceae, and its roots are medicinal, and it has long been regarded as a famous medicine for immortal, beneficial, and slimming.
茵陳 蒿 says medicinal material that dries the above-ground part of the chrysanthemum family.茵陳 蒿 is used for heat-induced jaundice, that is, symptoms associated with acute hepatitis, generalized yellowing, symptoms with red urine and less urine. It is also used for chronic hepatitis, cirrhosis, liver cancer, cholecystitis, and gallbladder stones. It is also used for skin diseases such as eczema, scabies, psoriasis, and rubella, as well as high fever and mad symptoms due to infection. As a pharmacological action, a bile secretion promoting action, antipyretic action, diuretic action, antimicrobial action, experimental water-resistant cancer cell inhibitory effect and the like have been reported.

  Nippon Toki is also called “Il-bon-dang-qui”, “Oae-gang-whal”, “Cha-dang-qui”, “Gat-dang-qui” in Korean, and can be used at the seaside (border). grow up. The mature root of Toki is called Japanese Toki, and it is used as a medicine, but it has immune function and is used for anticancer agents, etc., and it is used for anemia, irregular menstrual flow, cold knee pain, body pain, tonic, etc. used. Pharmacological effects have been reported to lower blood pressure and have a diuretic effect.

Human swallowtail has the effects of live blood, gluteal muscle, healthy spleen, and beneficial kidney. It treats low back pain, limb paralysis, half body insufficiency, wilt, facial nerve paralysis, and childhood sequelae caused by rheumatism.
Japanese nematode is a perennial herb that is effective for analgesia, antispasmodic, gout, and active blood.
Zion refers to the root of the Zionaceae, with a unique odor, tingling, a little bitter and sweet, and warm in nature. Zion softens the lungs and is used for cough, sputum, asthma, benevolence, and flat asthma, especially for treating coughing and bloody symptoms over time. It is also used for sore throat and acute chronic respiratory infections. As a pharmacological action, coughing, expectorant, antibacterial, ascites cancer inhibitory action has been reported.

Murasaki is a vine that grows on a tree branch that extends over water such as lakes, ponds, and swamps.
Glaze is a general term for perennial grasses of the family Butteroptera, large flowers, beautiful and cultivated in the garden for ornamental purposes. It has a blood-purifying effect, eliminates hemoptysis, and is used for fever, vomiting, clogging, and bruising.
Crimson carrot is a perennial grass of the dicotyledonous Oleaceae and is used as an antitussive, expectorant, antipyretic, tonic and draining agent.
Niwaurushi is a term that refers to the root bark of elderfish in Chinese medicine, and is effective for symptoms of obi, diarrhea, and bloody stool.
The moth is a moth from the family Basidiomycete, Hydrangea, and is used as a diuretic in Chinese medicine.

Red cocoon is a mycorrhizal sclerotia of the moss of Paranoid moss that parasitizes pine root, and is a medicinal material made by removing the outer layer. Useful for urination, abdominal and systemic edema, coughing due to sputum, vomiting, diarrhea, forgetfulness due to irritability, stigma, and heart edema. As pharmacological actions, diuresis, antibacterial action, intestinal relaxation action, ulcer prevention effect, hypoglycemic action, increased cardiac contractility, immune enhancement action, antitumor action, etc. have been reported.
Akadoshiku refers to a medicine made by drying the roots of red tsurudukudami. Used to protect the intestines and stop diarrhea.

Red cabbage is a kind of cabbage belonging to the Aplanidae family, and is one of the typical healthy vegetables that have effects such as gastric ulcer and prevention of aging and liver function recovery. Because of its beautiful color, it is often used as a decoration for Zalada and is also used as a sprout vegetable. There are more nutrient components such as fructose and sucrose, vegetable protein lysine, vitamin C, etc. than white ordinary cabbage. In addition, it is rich in vitamin U, has an effect on gastric ulcer, and is rich in selenium (selenium) that plays a role in preventing aging, mercury poisoning, and liver function recovery, and is a typical healthy vegetable.
Red glaze is a type of glaze that is reddish if you cut its roots.
Maehu is a perennial herb that is used in Chinese medicine for headaches, coughs, and sputum.

Rowan is obtained by removing the rough skin of rowan, which is a deciduous small oak tree of the dicotyledonous leaflet subfamily Coleoptera, Rhodaceae. It has tonic, gale, and antitussive effects, and treats body weakness, back and knee pain, wind cramps, cough, and gray hair.
Dingka, also called clove, is known to be good for appetite because it is sweet but spicy.
Mongkok says the fruit of the leguminous honey bee. Mongkok has a strong expectorant effect and is used for pulmonary tuberculosis, lung abscess, chronic bronchitis and the like. It is also used for mental confusion caused by moderate winds, personnel affairs, and wrinkles, and for swelling, skin ulcers, and constipation. Pharmacological effects have been reported such as gastric mucosal stimulation, mucus secretion promotion in respiratory tract, antibacterial action, central nerve palsy and the like.

Kakuko Sakai refers to a bite of a legume. The horned horn has a strong drainage and anti-inflammatory effect, and it is used for swelling and neutralizes skin venom. Antipyretic and anti-inflammatory effects of acute tonsillitis have been reported as pharmacological effects.
Sasakusa refers to the monocotyledonous rice of the family Gramineae.
Salmon, also known as meat candy, is a medicinal material made using meat stalks of meat shark or other related plants of the same genus. Flesh supplemented with cheerfulness, constipation caused by dryness of the intestines, low back pain due to lack of kidneys, weak feet and weakness, tinnitus, amnesia, genitals, enuresis, infertility, lower belt, cold lower abdomen Used for major bleeding, sweating, and constipation. As pharmacological effects, reduction of blood pressure, promotion of salivation, improvement of respiratory paralysis, etc. have been reported.

Bamboo candy is a term used in Chinese medicine to refer to the thin endothelium of kurochiku, which has the effect of lowering fever, stopping vomiting, relieving wrinkles, and stabilizing the fetus.
The ground bone skin refers to a chemical material obtained by drying the root bark of persimmon or other related plants. It is good for cold sweat, cough, asthma, vomiting, nosebleed, urinary bleeding, hyperglycemia, plaster, and neuralgia, headache, shoulder pain, muscle pain, low back pain, low back and knee helplessness. Use in some cases. As for the pharmacological action, the blood pressure lowering action and the blood glucose lowering action of cardiovascular pain have been reported.
Inoki refers to the stem skin of Kemponashi. Inoki has helped blood circulation, relaxed muscles, and has been reported to have a hepatoprotective action as a pharmacological action.

The known mother is a monocotyledonous lily genus maternal plant, and the rhizome contains asponin, sarsapogenin, and the like that can be used as components of medicines. In Chinese medicine, rhizome is used as a medicine, but it is reported that it is effective as an antipyretic agent for chronic bronchitis, diabetes and the like.
Chikiko refers to the annual grass species of the red crustaceae. Gionko is used as a tonic and diuretic and is reported to be used as a drug for hyperthyroidism and atopic symptoms.

The real fruit is a fruit of a young boy who treats stagnation and feelings of swelling of the chest and stomach, painful pain when pressed, edema, dyspepsia, constipation, etc. It became clear that it was effective for anal prolapse. As for the pharmacological action, uterine contractile action, gastrointestinal motility enhancing action, cardiotonic action, diuretic action and the like have been reported.
Earthenware is a drug name for bitumen, and is used for diarrhea, colitis, hemorrhage, pressure sores, burns, etc., and is particularly used for stopping various bleedings because of its strong hemostatic action.

Ground yellow is a plant of the genus Ligaceae, and in Kampo, the raw material of the root is called dough yellow, the dried one is dried yellow, and the one dried by steaming is called mature yellow. Mature yellow is used as a blood-replacement agent, and is used for menstrual irregularities, weak constitution, poor growth of children, dementia, premature ejaculation, erectile dysfunction, and dough yellow is frail constitution, vomiting, nosebleed, uterine bleeding, irregular menstrual constipation It has been reported that dryland yellow is effective in dry mouth after fever and depletion due to heat inside the organ, and stops bleeding and nosebleed.
Souuzu is a mushroom plant, and in Chinese medicine, dried roots are used as a medicinal material, but it is effective for gout, analgesia, diuresis, arthritis, muscle and bone cramps, jaundice, and no urine. It has been reported to be used sometimes.

Shingoka is a kind of Goka. Externally, it eliminates wind and humidity, allows meridians to penetrate well, has analgesic action, makes liver and kidney functions healthy, and makes muscles and bones healthy.
Small citrus grass is an annual plant of Euphorbiaceae that grows in fields and grasslands, and is known to have the effect of improving chronic hepatitis, nephritis, vaginitis, dysentery and visual acuity.
Chen is a medicinal product of tangerine peel. Chen relieves qi and strengthens the function of fat, treating abdominal distension, nausea, vomiting, nausea, indigestion, gaspy symptom, and loose stool symptoms. Removes cough, sputum, and acts as a diuretic. Pharmacological effects have been reported that essential oil components have fire extinguisher stimulation, digestion promotion, expectoration, anti-ulcer, gastric juice secretion suppression, cardiac intensification, blood pressure increase, antiallergy, bile secretion promotion, uterine smooth muscle suppression, antibacterial action and the like.

Car Maeko is a word that refers to the seed of plantain in Chinese medicine. The forehead is used to improve urination, relieve diarrhea, improve vision, and stop coughing.
Miko is the fruit of Onamomi from the Asteraceae family. Humiko is a drug that eliminates wind and cold, and is used for empyema, rhinitis, headache, fever, cough, limb pain paralysis, and when it is not free to flex and stretch, skin itch, and otitis media. Pharmacological effects have been reported on essential oils and alkaloids, such as toxic reactions, hypoglycemia, leukopenia prevention, antitussives, and cardiac suppressive effects.
Senkyu is a celery family, and in Chinese medicine, the rhizome is effective for sedation, analgesia, and tonic, and is used for headaches, anemia, gynecological diseases, and the like.

Tenma refers to a perennial grass of the monocotyledon orchid family, and uses the whole plant for tonic, nervous breakdown, dizziness and headache.
Tianmen Winter is a lily family plant that uses edible branches and roots as antitussive, diuretic and tonic. Contraindications have been reported not to apply to people who are cold, weak intestines and have diarrhea.
Kawamata is a persimmon skin of the Geika department or a genus of the same genus, and is a medicinal material made by removing seeds to the maximum extent. Kawamata is used for abdominal pain due to cold in the abdomen, diarrhea and toothache, asthma, low back pain, has insecticidal action, and is also used for scabies, psoriasis, genital itching, scrotal eczema and so on. As a pharmacological action, local intoxication action, intestinal fistula action, antibacterial action, etc. have been reported.

Semuzu is prescribed for Kampo medicine for dysuria, urinary calculi, lymphadenitis, hemorrhoids, uteritis, hemorrhoids, convulsions, and hemorrhoids. As a folk remedy, when bitten by snakes or insects, it is crushed and scratched.
Millennials improve blood circulation and are effective in treating heart and stomach pain, antipyretic sedatives, cough, dysentery, hemorrhoids, bronchial asthma, lack of sleep, etc.
Uchiwadokoro uses rhizome as a medicinal material in Chinese medicine, but it is taken in liquor when the phlebotomy hardens and solidifies, and it is used for coronary artery injury caused by phlebotomy, and it occurs due to lung fever It is used for swelling and skin rash because it relieves cough and asthma and lowers blood fever.

Tenzan Snow Lotus is a perennial grass of the genus Mushroom, which helps men's rejuvenation and has great effects on various gynecological diseases, cold diseases, kidneys, arthritis, diabetes, wind and humidity, cold uterus, etc. Is said to be large.
Heavenly pollen refers to the roots from which the skin layer of the Cucurbitaceae or Eucalyptus is removed. Treats depletion, swelling, and pus when the fluid is damaged by heat. It mainly lowers the heat of the lungs and stomach, and makes a tsu liquid to eliminate dry mouth and make the body comfortable. As pharmacological effects, malignant abortion and epithelial cell carcinoma suppression, uterine smooth muscle excitement, liver cancer suppression effect, hypoglycemic effect, antibacterial activity and the like have been reported.
Qingdao treats nausea, headaches and vomiting due to malaria and summer heat, and treats bone pain, fever and summer cold caused by fever. Improve the complexion and blacken the gray hair. As pharmacological effects, malaria parasite suppression, liver dystomia suppression, blood pressure lowering, antipyretic, skin fungal suppression, antitussive, expectorant, asthma, bile secretion, immunoregulatory action, etc. have been reported.

Grass is a plant belonging to the family Ginger, and in Korea uses grass fruit. Grasses warm the spleen stomach, remove moisture, and are used for abdominal pain, abdominal distension, nausea, vomiting and diarrhea.
Kusanagi is a medicinal material made from tuberous roots of the genus Ranunculaceae or related plants of the same genus. Kusanagi is used for headaches, abdominal pains, swellings, lack of body, lack of personnel, and facial paralysis. It is applied to paralysis symptoms caused by wind and humidity, personnel regret, rheumatoid arthritis, neuralgia, low back pain, tetanus, etc., and abdominal pain caused by cold stomach. As pharmacological effects, there are analgesic, sedative, anti-inflammatory, and local paralysis alleviating effects, and cardiac exercise excitability has been reported when taking a large amount.
Yasuko refers to the fruit of the evergreen shrub of the Rubiaceae family. In Kampo, it is used to treat insomnia and jaundice and is reported to have anti-inflammatory, hemostatic and diuretic effects.

Seiso cow is a species of Amaranthaceae. Seiso cow lowers liver fever, so it is used for symptoms of hyperemia, eye sight, tearing and avoiding light, high blood pressure, and headache. As a pharmacological action, it is used for ophthalmic diseases and applied to skin products.
The hollyhock refers to the hollyhock of the mallow family. The hollyhock is used for white belts, cold abdomen of the lower abdomen, urination of the stool, bleeding, uterine bleeding, burns, redness of the nose. As a pharmacological action, malaria has been reported to be effective.
Agarwood is an evergreen tree of the genus genus, and in Kampo, the stem is used as a medicine, but it has sedation, healthy stomach, aeration, indigestion, poor eating, vomiting, bronchial asthma, premature ejaculation, energy, lack of energy This is effective.

Sawaran refers to the above-ground part before the blooming of Shironet of the Labiatae family. Sawaran is used for amenorrhea caused by hemoptysis, menstrual pain, postpartum abdominal pain, and bruises, and is effective for swelling, liver dysfunction, and difficulty in urinating postpartum. Among the drugs that relieve hemoptysis, it has the advantage of not sacrificing spirit and is often applied in gynecology. Cardiac action has been reported as a pharmacological action.
Heramodaka has been reported in Chinese medicine to use rhizomes as a diuretic, edema and gonorrhea.
Karasuta is a fruit of karachia, fragrant and medicinal.
Earthenware refers to the roots of Sartorius roses. The soil contains a lot of starch and is known to be effective for constipation, syphilis, gonorrhea, fetal toxin, scab, chronic dermatitis, mercury poisoning, cold, and neuralgia.

The silkworm is a species of the mosquito that is an annual vine plant belonging to the convolvulaceae family. Yuzuko is known as a medicine that mainly protects the liver and kidneys, improves vision, helps cheerfulness, and makes kidney function healthy. It is effective for male impotence caused by weak kidneys, natural semen discharge, and dreaming. Healing bones, strengthening lumbar strength, treating cold and painful symptoms of the hips and knees due to weak kidney function. It has also been reported to treat pollakiuria, dysuria, and diarrhea and is effective in treating diabetes.
Soil cucumber is a medicinal product of soil senkyu root, and is used for treatment of antispasm, sedation, blood pressure enhancement, vasodilation, antibacterial action and the like.
Tsutsukusa refers to the stem of the camillaraceae of the family Araceae. Tsutsumi has been reported to lower fever, increase urine volume, and promote hemorrhoids, urethritis, cystitis, and postpartum lactation.

Brahma is also called “No-ni” in Korean, and leaves, stems, flowers, fruits and seeds have been used for folk remedies. It has become clear that it contains components such as anthoquinone and serotonin, which helps digestion, reduces pain, and is effective against high blood pressure and cancer.
A soybean is an evergreen oak leaf shrub belonging to the Euphorbiaceae family, and it is the species in Chinese medicine. It is a spicy and hot poison, and is used when the abdomen is full of water and makes you feel hungry or constipated.
Kang Ying is a medicinal product obtained by drying the whole plant of Kantou dandelion or related plants. A medicine that lowers heat poison and relieves swelling, and is used for swelling, mastitis, sore throat, and atheroma (appendicitis, lung abscess, peritonitis), and it is difficult for urine to develop due to eye redness, acute hepatitis, jaundice, and heat Use for symptoms. As pharmacological actions, antibacterial action, immune function enhancement, bile secretion action, liver function protection action, and diuretic action have been reported.

Scarlet yellow refers to the pollen of the catfish or related plants. Scarlet yellow reduces blood fever, has convergence and hemostasis, is used for hemoptysis, vomiting, nosebleed, urinary bleeding, uterine bleeding, improves blood circulation, blood abdominal pain caused by coagulation in the chest, postpartum Used for hemoptysis and menstrual pain. As pharmacological actions, uterine excitement, blood pressure lowering, antispasmodation, shortening of blood coagulation time, growth inhibition of Mycobacterium tuberculosis, cholesterol lowering action, etc. have been reported.
Orchid orchid is a perennial grass of the Orchidaceae family, the rhizome is fleshy and ellipsoidal, the leaves are petiole, egg-shaped or egg-shaped oval. In fact, it is a fruit.
Hakone is native to China and cultivated as a medicinal plant. In traditional Chinese medicine, it refers to reddish brown tuberous roots and is used as a tonic, tonic, and soothing agent. The leaves are green and attached to the swollen leaves to absorb pus.
Kusanem has the effect of lowering heat, removing wind, and detoxifying. Used to treat colds caused by wind, jaundice, dysentery, abdominal distension, dermatitis, etc.
Anjin is a term used to describe apricot seeds in Chinese medicine, and is used for cough, asthma, constipation, and so on.

Sunflower is a sunflower seed that reduces cholesterol levels and prevents cardiovascular disease and arteriosclerosis. In addition, it is rich in minerals such as calcium, potassium and iron, has a weak fire extinguisher, and is good for cold and weak people. Excellent effect on hypertension and nervousness.
Katsuki is a perennial grass of the family Cyperaceae, and the tuberous root at the tip of the root contains essential oils and fatty oils, and in Chinese medicine, it is used irregularly for headache, abdominal pain and menstruation, and also used as an antitussive agent for pulmonary tuberculosis in the private sector. It has been reported.
Kouji is a Labiatae plant and has been reported to be used as a sweat, antipyretic, diuretic, hemostatic agent to treat the product, beriberi, edema, gastritis, nosebleed and bad breath.
Kogaku refers to the fruit of Kogaku. Kaoru is effective for gale, chills, and pain relief, and treats wind sensation, cardiogastric pain, rheumatoid arthralgia, and mania.
Aroma reduces blood fever, has convergence, hemostasis, is used for hemoptysis, vomiting, nosebleed, urinary bleeding, uterine bleeding, improves blood circulation, blood abdominal pain caused by coagulation in the chest, postpartum hemoptysis Used for pain and menstrual pain. As pharmacological actions, uterine excitement, blood pressure lowering, antispasmodation, shortening of blood coagulation time, growth inhibition of Mycobacterium tuberculosis, cholesterol lowering action, etc. have been reported.

Gensen is a perennial grass of the Genus family, and Kampo has been reported to use roots as antipyretic agents for sore throat, swelling and lymphadenitis.
Genokosho is an annual plant of the family Aceraceae that removes customs and promotes blood circulation to make the skeleton and muscles healthy, so it is used for limb paralysis pain, joint disadvantages, bruises, and so on. It is also effective against dysentery and chronic diarrhea abdominal pain and vaginitis, and is also effective against itchy skin, scabies and scabies.
Genpang is a perennial plant belonging to the family Papaveraceae, and it has been reported in Chinese medicine that tubers are used as semen, antispasmodics and analgesics.
Persimmon is an annual grass of Lamiaceae. In Kampo, it refers to dried whole grass, and it is used when you get a fever from a cold, a headache, a sore throat, blood from a swollen place. It has been reported.
Sesame seed is a term that refers to sesame seeds and black sesame in Chinese medicine. It is known to supplement liver and kidneys, and is effective for people with white hair.

Pepper is an annual plant of the family Rumeaceae, and the seeds of pepper are mainly dried in the sun and used for medicinal purposes. The seed contains a very small amount of essential oil, which contains about 40 components: various types of alkaloids, proteins, fats and the like. Warm, non-toxic, used in Africa, the Middle East, India, etc. to treat bladder and kidney diseases from old times, and also used to treat people with cold sweat and cold stomachs ing. In recent years, it is known to be effective in maintaining the balance between blood sugar and insulin in the body, and also effective in weight control, and has been actively studied.
Pumpkin is a vegetative annual plant of the Cucurbitaceae family and has the highest starch content among fruits and vegetables, and is known to have the highest calories after potatoes, sweet potatoes and beans. Although normally used for cooking, ripe fruit contains a large amount of vitamin A, contains a small amount of vitamins B and C, and is very important as a vitamin source.

Scarlet five-sided skin refers to purple-red elephants.
Red ginseng is red ginseng steamed from dried ginseng and has sedative and excitatory effects on the central nervous system and acts on the circulatory system to prevent hypertension and arteriosclerosis. On the other hand, it lowers hematopoiesis and blood sugar levels, protects the liver, acts on the endocrine system, indirectly acts on sexual behavior and reproductive effects, has anti-inflammatory and anti-tumor effects, and protects against radiation It also has the effect of protecting and softening the skin. The most important effect of red ginseng is the adaptogen effect, which increases the ability to defend against various harmful effects of tears caused by the surrounding environment, various stresses, and adapts the living body more easily. It has been scientifically proven that it has the ability to
Kombu tea is a black tea containing sugar, cultivating yeast, and has effects such as cancer suppression, cholesterol and blood pressure lowering, and hangover prevention.
Red clover is a leguminous perennial grass, and folk remedies use the whole plant as a medicinal material for diuresis, analgesia, digestive stomach, hemorrhoids, hemostasis and the like.

Safflower is used in Chinese medicine for gynecological diseases, menstrual pains, and abdominal pains, and the oil from the fruit is salty and made kerosene and edible, and the oil from the seeds contains a lot of linoleic acid, and arteries caused by excessive cholesterol Good for prevention and treatment of sclerosis.
The flower coat is located on the outside of the stamens and pistils, is a floral element that protects the stamens and pistils, and is also called a flower cap.
Ogon refers to perennial grasses of the Labiatae family, and the Kampo uses roots as antipyretic, diuretic, antiphlogistic, expectorant and anti-inflammatory agents.
Twilight refers to the perennial grass of Legumes. Commonly cultivated as a medicinal herb, in Kampo, collected in the fall, removed outcrop and whisker roots, dried in the sun is called Kampo jaundice, and has effects such as tonicity, antiperspiration, diuresis and antitumor Yes, it is reported to be prescribed for physical weakness, fatigue fatigue, bloody collapse, anal prolapse, uterine prolapse, visceral sewage, cold sweat, peripheral nerve, etc.

Huang Ren is cultivated for herbal medicine, and in Kampo, it has effects such as healthy stomach, sedation, anti-inflammation, antibacterial, indigestion, gastritis, vaginitis, abdominal pain, vomiting, dysentery, heartbeat, anxiety, mental anxiety, throat Prescribe for treatment of pain, vomiting, nosebleeds, melena, burns, etc.
Miyamanarukoyuri is a word that refers to the roots of Miyama Narukoyuri in traditional Chinese medicine, and is used as a supplement to weaken the body and to lose weight.
Dankoubai means dried small branches of Dankoubai. In Kampo, it is used as a medicine for hemoptysis, abdominal pain, postpartum pain, and hemorrhoids.

  Jaundice refers to the dried skin of jaundice belonging to the Citrus family, which inhibits the growth of blood cells, pneumococcus, Streptococcus pneumoniae, Mycobacterium tuberculosis, Staphylococcus, etc. It has a bactericidal action. In the case of taking it, the secretion of gastric juice is promoted by promoting the taste reflex, which also promotes food consumption. Since general alkaloids do not have systemic effects and do not have side effects even when administered in large amounts, they can be used not only for intestinal regulating agents but also for healthy stomachs. Moreover, since various bacterial resistance does not arise with respect to this chemical | medical material, when epidemic eye disease prevails, it can be used also as a face-wash disinfectant. In addition, effects such as blood pressure lowering, central nervous system suppression, and anti-inflammation have been reported, and in Oriental medicine, they are used for Hou Ren Deto, Toko-Kei-Kyoto, Torento, etc.

Kopaku is an evergreen tree of the dicotyledonous genus Coleoptera, which is used for asthma and gastrointestinal diseases.
Kuroshikaushi is a black seed of morning glory, and is used when ascites is filled with chronic pyelonephritis, hepatic sclerosis, etc., when swallowing is strong due to its high armpit and diuretic effects.
Menamomi refers to a medicinal material made from the Comamenaceae of the Compositae family or the above-ground part of Menamomi. Menamomi removes wind and moisture, and is used for arthritis, limb pain paralysis, flexion / extension disadvantage, weakness of the lower limbs and involuntary half wind, etc., and it is used for swelling, rash, itchy skin, eczema and the like. Used for high blood pressure, headache, dizziness, acute hepatitis, etc. As pharmacological effects, joint edema suppression and blood pressure lowering effects have been reported.

  The wrapped and fermented extract utilizing the medicinal flower of the present invention includes a step of boiling or steaming a washed and dried natural product for 30 minutes to 2 hours, and a step of cooling the cooked or steamed natural product at room temperature for 30 minutes to 1 hour; Wrapping cooled natural products in medicinal flowers or covering them with medicinal flowers, placing them in unglazed pottery and fermenting them at room temperature for 4-7 days in a shaded place, removing medicinal flowers from the fermented natural products and extracting them And manufactured by.

  Generally, when fermenting a natural product without mixing sugar, salt or yeast, the natural product rots without fermenting, but when the natural product is fermented using medicinal flowers according to the method of the present invention, There is an advantage that natural products can be fermented without decay without the addition of sugar, salt or yeast. In addition, when the natural product is fermented using the whole form of the medicinal flower as it is without pulverizing and mixing the medicinal flower by the method of the present invention, the natural product and the medicinal flower are easily separated and mixed. There are advantages that are more effective than time.

  At this time, the amount of the medicinal flower used at the time of fermentation is not particularly limited, but it can be preferably used in an amount of 1 to 40% by weight based on the weight of the natural product to be fermented.

  In the present invention, water or an organic solvent can be used as the extraction solvent, and more specifically, selected from the group consisting of purified water, methanol, ethanol, glycerin, ethyl acetate, butylene glycol, propylene glycol, dichloromethane and hexane. One of these can be used alone or in admixture of two or more.

  At this time, the extraction temperature is preferably 10 to 80 ° C., and the extraction is preferably performed for 6 to 24 hours. If the extraction temperature and the extraction time are exceeded, the extraction efficiency may decrease or the components may change.

  After obtaining an extract using the solvent, a liquid material can be obtained by ordinary methods known in the art to be immersed, heated and filtered at room temperature, or an additional solvent can be added. A wrapped fermentation extract can be produced by evaporation, spray drying or freeze drying.

  The wrapped fermented extract of the present invention is contained in an amount of 0.001 to 30% by weight based on the total weight of the composition. If the amount is less than 0.001% by weight, the desired effect cannot be expected. If the amount exceeds 30% by weight, the increase in the effect is slight compared to the increase in the content, and the dosage form stability is deteriorated. There is.

  The packaged fermented extract using the medicinal flower according to the present invention is very excellent in skin antioxidant, anti-aging, whitening and moisturizing effects.

  In the skin external preparation composition of the present invention, the skin external preparation composition comprises a softened long water, a nutritional lotion, a massage cream, a nutritional cream, an essence, a pack, a gel, an ampule or a skin adhesive type cosmetic dosage form. It is characterized by having or having a transdermal dosage form such as lotion, ointment, gel, cream, patch or spray.

  EXAMPLES Hereinafter, although this invention is demonstrated in detail based on an Example and a test example, the scope of the present invention is not necessarily limited to these examples.

[Example 1] Manufacture of black bean extract wrapped and fermented with lotus 1.5 kg of commercially available black bean (= Sasamemeta) was placed in 2 L of water and boiled for 1 hour on medium heat (60-80 ° C). . After the boiled black beans were taken out, they were cooled at room temperature for 1 hour, and each 30 g of the cooled black beans was wrapped in a lotus and wrapped, and then tied tightly with cotton thread so that the lotus would not fray. The material made by wrapping black beans boiled in this way in a lotus was placed in an unglazed pottery and stored in a shaded place at room temperature for 7 days. Next, after removing the lotus, the black beans were collected and pulverized with a mixer, and then 7 L of a 70% ethanol aqueous solution was added, extracted by refluxing three times, and immersed at 15 ° C. for 1 day. Thereafter, the residue and the filtrate were separated by filter cloth filtration and centrifugation, and the separated filtrate was ablated under reduced pressure to obtain 195 g of a lotus-wrapped fermented black bean extract.

[Comparative Example 1] Production of black bean extract After pulverizing 1.5 kg of commercially available black bean (= Sasame-ta) with a mixer, 7 L of 70% ethanol aqueous solution was added and extracted under reflux three times. Soaked for days. Thereafter, the residue and the filtrate were separated by filter cloth filtration and centrifugation, and the separated filtrate was ablated under reduced pressure to obtain 180 g of a black bean extract.

[Comparative Example 2] Manufacture of general fermented black bean extract 1.5 kg of commercially available black bean (= Sasameta) was put in 2 L of water and boiled for 1 hour on medium heat (60-80 ° C). After the boiled black beans were taken out, they were cooled at room temperature for 1 hour, and the cooled black beans were put in an unglazed pottery and stored in a shaded place at room temperature for 7 days. At this time, unlike in Example 1, it was observed that black beans were not fermented properly and rotted. Thereafter, the black beans were pulverized with a mixer, 7 L of a 70% ethanol aqueous solution was added, and the mixture was extracted by refluxing three times and then immersed at 15 ° C. for 1 day. Thereafter, the residue and filtrate were separated by filter cloth filtration and centrifugation, and the separated filtrate was ablated under reduced pressure to obtain 231 g of a general fermented black bean extract.

[Comparative Example 3] Production of general fermented lotus extract 1.5 kg of commercially available lotus was put in 2 L of water and boiled on medium heat (60-80 ° C) for 1 hour. After the boiled lotus was taken out, it was cooled at room temperature for 1 hour, and the cooled lotus was put in an unglazed pottery and stored in a shaded place at room temperature for 7 days. At this time, it was observed that the fermentation of the lotus was not performed properly and rotted. Thereafter, after lotus was pulverized with a mixer, 7 L of 70% ethanol aqueous solution was added, extracted by refluxing three times, and then immersed at 15 ° C. for 1 day. Thereafter, the residue and the filtrate were separated by filter cloth filtration and centrifugation, and the separated filtrate was ablated under reduced pressure to obtain 105 g of a general fermentation lotus extract.

[Comparative Example 4] Manufacture of black bean extract mixed with lotus and fermented 1.2 kg of commercially available black bean (= Sasame thick) was placed in 2 L of water and boiled for 1 hour on medium heat (60-80 ° C.). . After taking out the boiled rice cake, it was cooled at room temperature for 1 hour, and the cooled black beans and lotus 0.3 kg were mixed well. The material made by such a method was put into an unglazed pottery and stored in a shaded place at room temperature for 7 days. At this time, it is very difficult to separate the lotus from the black beans. After pulverizing with a mixer in a mixed state, 7 L of 70% ethanol aqueous solution was added, extracted by refluxing three times, and then immersed at 15 ° C. for 1 day. . Then, the residue and the filtrate were separated by filter cloth filtration and centrifugation, and the separated filtrate was ablated under reduced pressure to obtain 254 g of a lotus mixed fermented black bean extract.

[Test Example 1] Antioxidant effect test (DPPH test)
In order to examine the antioxidant effect of the extracts prepared in Comparative Examples 1 to 4 and Example 1, the organic radical DPPH (1,1-diphenyl-2-picrylhydrazyl; 1,1-diphenyl-2- The antioxidative ability was evaluated by comparatively measuring the DPPH oxidation inhibitory effect through a change in absorbance generated by reduction of picryl hydrazyl (antioxidant is oxidized). That is, for the extracts obtained in Comparative Examples 1 to 4 and the extract obtained in Example 1, measure the degree to which the oxidation of DPPH is suppressed and the absorbance decreases compared to the control group, A concentration showing an absorbance of 50% or less compared to the absorbance of the control group was evaluated as an effective antioxidant concentration.

After adding 190 μL of 100 μM (in ethanol) DPPH solution and 10 μL of each of Comparative Examples 1 to 4, Example 1 and positive control group obtained above to prepare a reaction solution and reacting at 37 ° C. for 30 minutes, 540 nm Absorbance was measured at. As the positive control group, Trolox, a widely used synthetic antioxidant, was used. The results of DPPH analysis of each substance are shown in Table 1 below, and IC ₅₀ means the concentration of the sample when the absorbance is reduced by 50% by the added sample.

  As can be confirmed from Table 1 above, the antioxidant ability of the lotus-wrapped fermented black bean extract of Example 1 was mixed with the raw product extract (Comparative Example 1) and the lotus to ferment the black beans (Comparative Example). It was not only much better than 4) but also much better than the synthetic antioxidant Trolox used as a positive control group. Moreover, it turned out that the general fermented extract (comparative example 2) which fermented the black bean without medicinal flowers and the medicinal flower independent fermented extract (comparative example 3) have little antioxidant effect. Therefore, it was found that the medicinal flower-wrapped fermented extract according to the present invention has an excellent antioxidant effect.

[Test Example 2] Anti-aging effect test I (measurement of collagenase expression inhibitory effect)
The collagenase production inhibitory ability of the extracts obtained in Comparative Examples 1 to 4 and Example 1 was measured in comparison with tocopherol and EGCG. Tocopherol and EGCG are antioxidants, and are known to have a function of preventing skin aging by regenerating skin epidermal cells.

The test consisted of 5,000 human fibroblasts in a 96-well microtiter plate containing DMEM (Dulbecco's Modified Eagle's Media) medium containing 2.5% fetal bovine serum. The cells were cultured until they were grown to about 90%. Then, after culturing in serum-free DMEM medium for 24 hours, each of the extracts of Comparative Examples 1 to 4, Example 1 dissolved in serum-free DMEM medium, tocopherol and EGCG was treated at a concentration of 10 ⁻⁴ mol for 24 hours. After that, the cell culture medium was collected.

  The degree of collagenase production was measured using a commercially available collagenase measuring instrument (Amersham Pharmacia, USA) from the collected cell culture. First, the collected cell culture solution was put in a 96-well plate uniformly coated with the primary collagenase antibody, and the antigen-antibody reaction was carried out in a thermostatic bath for 3 hours.

  After 3 hours, the secondary collagen antibody to which the chromophore was bound was placed in a 96-well plate and allowed to react for an additional 15 minutes. After 15 minutes, a color-inducing substance is added, color development is induced at room temperature for 15 minutes, and when 1 M sulfuric acid is added to stop the reaction (color development), the color of the reaction solution becomes yellow, and the yellow color depends on the progress of the reaction. Appeared differently.

The absorbance of a yellow 96-well plate was measured at 405 nm using an absorptiometer, and the degree of collagenase synthesis was calculated according to the following formula 1. At this time, the reaction absorbance of the cell culture solution collected from the group not treated with the composition was used as a control group. That is, the expression level of collagenase in the untreated group was set to 100. On the other hand, the expression level of collagenase in the group treated with the test substance was determined, and the results are shown in Table 2 below.

  The lower the expression level of collagenase, the higher the ability to suppress the expression of collagenase, the less collagen degradation occurs in the skin, and the smaller the amount of wrinkles produced. From Table 2 above, the lotus-wrapped fermented black bean extract according to the present invention is an in vitro extract (comparative example 1) and an extract obtained by mixing black beans with fermented black beans (comparative example). 4) It was confirmed that collagenase expression was effectively suppressed, and that collagenase expression suppression ability was superior to tocopherol known as an antioxidant. In addition, the general fermented extract obtained by fermenting black beans without medicinal flowers (Comparative Example 2) and the medicinal flower single fermented extract (Comparative Example 3) have a similar level of collagenase expression suppression ability as the non-treated group. It turns out that there is almost no aging effect.

  Therefore, it was found that the medicinal flower-wrapped fermented extract according to the present invention effectively suppresses the expression of collagenase, thereby reducing collagen degradation in the skin and being excellent in anti-aging effect.

[Test Example 3] Anti-aging effect test II (procollagen production promoting efficacy experiment)
The procollagen producing ability of the extracts obtained in Comparative Examples 1 to 4 and Example 1 was measured in comparison with vitamin C. Procollagen is a collagen production-inducing substance and is a substance necessary for the production of collagen and prevention of aging, and vitamin C is known as an essential component in the synthesis of collagen.

The test consisted of 5,000 human fibroblasts in a 96-well microtiter plate containing DMEM (Dulbecco's Modified Eagle's Media) medium containing 2.5% fetal bovine serum. The cells were cultured until they were grown to about 90%. Then, after culturing in serum-free DMEM medium for 24 hours, each of the extracts of Comparative Examples 1 to 4 and Example 1 and vitamin C dissolved in serum-free DMEM medium was treated at a concentration of 10 ⁻⁴ mol for 24 hours. Thereafter, the cell culture medium was collected. After 24 hours, the amount of procollagen released into the medium was measured using a procollagen type-1 C-peptide EIA kit (MK101, Takara, Japan).

  The production level of procollagen in the untreated group was set to 100, and the production level of procollagen in the group treated with the test substance was determined. The results are shown in Table 3 below.

  The higher the production level of procollagen is, the higher the production level of collagen is. Therefore, the generation of skin wrinkles can be prevented. According to Table 3, the lotus-wrapped fermented black bean extract according to the present invention is an in vitro extract (comparative example 1) and an extract obtained by fermenting black beans by mixing with a lotus (comparative example). 4) The production of procollagen was promoted more effectively, and it was confirmed that the production promotion degree of procollagen was superior to vitamin C, which is known as an essential component for collagen synthesis. In addition, the general fermented extract obtained by fermenting black beans without medicinal flowers (Comparative Example 2) and the medicinal flower single fermented extract (Comparative Example 3) have a similar level of procollagen production to the non-treated group, It turns out that there is almost no aging effect.

  Therefore, it was found that the medicinal flower-wrapped fermented extract according to the present invention effectively promotes the production of procollagen, thereby assisting the production of collagen in the skin and having an excellent anti-aging effect.

[Test Example 4] Whitening effect test (measurement of melanin production inhibitory effect using salmon pigment cells)
The melanin production inhibitory ability of the extracts obtained in Comparative Examples 1 to 4 and Example 1 was measured in comparison with hydroquinone.

Mel-Ab cells from C57BL / 6 mice (Dooley, TP et al, Skin pharmacol, 7, pp188-200), DMEM with 10% fetal bovine serum, 100 nM 12-O-tetra The cells were cultured in a medium supplemented with tetradecanoylphorbol-13-acetate and 1 nM cholera toxin under conditions of 37 ° C. and 5% CO ₂ . The cultured Mel-Ab cells were detached from 0.25% trypsin-EDTA, and the cells were cultured at a concentration of 10 ⁵ cells / well (cells / well) in a 24-well plate. Each test substance was added and cultured. As test substances, hydroquinone and the extracts of Comparative Examples 1 to 4 and Example 1 were each used at a concentration of 10 ppm. At this time, the hydroquinone was used as a positive control group. Next, after removing the culture medium and washing with PBS, the cells were dissolved with 1N sodium hydroxide, the absorbance was measured at 400 nm, and then the melanin production inhibition rate was calculated according to the following formula 2. Table 4 (Dooley's method).

  As shown in Table 4 above, the lotus-wrapped fermented black bean extract of the present invention is a melanin from a raw product extract (Comparative Example 1) and an extract obtained by mixing black beans with a lotus (Comparative Example 4). It was confirmed that the production of melanin was effectively suppressed and a melanin production inhibition rate similar to that of hydroquinone, which is a known whitening substance, was exhibited. In addition, the general fermented extract obtained by fermenting black beans without medicinal flowers (Comparative Example 2) and the medicinal flower single fermented extract (Comparative Example 3) are similar in level to the non-treated group in the ability to suppress melanin production, and are whitened. It turns out that there is almost no effect.

  Therefore, it turned out that the medicinal flower wrap fermentation extract which concerns on this invention is excellent in the whitening effect by suppressing the melanin production in skin effectively.

[Test Example 5] Irritation test In order to compare the usability of kojic acid, which is a known whitening substance, and the lotus-wrapped fermented black bean extract used as an active ingredient in the present invention, irritation such as pain and irritation Experiments were conducted on the degree of irritation such as pain and irritation in 15 subjects who were sensitive to feeling.

Apply 0.5 ml each of kojic acid (obtained from kojic acid, YM chemical) and lotus-wrapped fermented black bean extract (previously Example 1) at random on the left and right, and apply 0.1 points As a score between 0 and 3.0. The results are shown in Table 5 below.
<Evaluation criteria>
0 to 0.4: No irritation 0.5 to 1.0: Slight irritation 1.1 to 2.0: Normal irritation 2.1 to 3.0: Severe irritation

  As can be seen from Table 5, in the case of kojic acid, it has been found that there is a certain degree of irritation that is usually felt somewhat, with some irritation caused by pain and irritation. On the other hand, it was found that the lotus-wrapped fermented black bean extract used in the present invention is almost insensitive to both pain and irritation.

  Therefore, unlike the kojic acid, the lotus-wrapped fermented black bean extract of the present invention has no irritation and was able to be confirmed to provide a better feeling of use.

[Test Example 6] Skin moisturizing test (differentiation induction test of human keratinocytes)
In order to confirm the skin barrier function and skin moisturizing ability of the extracts of Comparative Examples 1 to 4 and Example 1, human keratinocytes that were primarily cultured in a test using absorbance were placed in a culture flask and placed at the bottom. After adhering, the extracts of Comparative Examples 1 and 2 and Example 1 were treated at a concentration of 1 ppm in the culture medium containing the test substances shown in Table 6 below, and then the cells were about 70 to 80% of the bottom area. Cultured for 5 days until grown. After the cells were harvested and washed with PBS (phosphate buffered saline), a 10 mM Tris-HCl buffer solution containing 2% SDS (Sodium Dodecyl Sulfate) and 20 mM DTT (Dithiothreitol) ( 1 ml of Tris-HCl, pH 7.4) was added and sonication was performed for 3 minutes, followed by boiling for 10 minutes. This was centrifuged at 1200 rpm for 30 minutes, the separated precipitate was further suspended in 1 ml of PBS, and the absorbance at 340 nm was measured.

  Separately from this, a part of the solution after the sonication was taken and the protein content was measured, which was used as a reference when evaluating the degree of cell differentiation. Table 6 below shows the results of tests conducted by adding a test substance to a low calcium concentration, with the low calcium (0.03 mM) treatment group and the high calcium (1.2 mM) treatment group as negative / positive control groups, respectively. .

  As shown in Table 6, as a result of measuring the amount of CE (Cornified Envelop) produced during differentiation of keratinocytes and comparing cell differentiation promoting effects, the lotus-encased fermented black bean extract according to the present invention Was found to promote differentiation in keratinocytes more effectively than Comparative Examples 1-4. Therefore, it was found that the medicinal flower-wrapped fermented extract according to the present invention enhances the skin barrier function and enhances the skin moisturizing ability.

Claims (11)

A skin external preparation composition containing, as an active ingredient, a fermented wrap extract produced by wrapping or covering a natural product with medicinal flowers ,
The natural products include beans, bitter rind, mung beans, solitary, bashken, bon bonsai, bonito, soy sauce, mulberry leaves, lotus seeds, gokazuku, tsumerengue, dogbill, dragon gall grass, longan grass, evening primrose, beneficial mother grass, carrot , Chen Chen, Red cabbage, Mongkok, Makiko, Shingoka, Mikoko, Kawamata, Uchiwadokoro, Tianshan Snow Lotus, Aoi, Kusanagi, Seisoushi, Earthen, Kusanem, Genokosho, Red Ginseng, and One or more selected from the group consisting of Menamomi,
The skin external preparation composition, wherein the medicinal flower is at least one selected from the group consisting of chrysanthemum, gold and silver flowers, kiso flower, kobushi, and lotus . The skin external preparation composition according to claim 1, wherein the medicinal flower is a lotus flower . The skin external preparation composition according to claim 1, wherein the natural product is black beans .   The skin external preparation composition according to claim 1, wherein the wrapping fermented extract is contained in an amount of 0.001 to 30% by weight based on the total weight of the composition. The skin external preparation composition according to any one of claims 1 to 4 , which is an antioxidant skin external preparation composition . The skin external preparation composition according to any one of claims 1 to 4 , which is an anti-aging external skin composition . A skin external composition for skin lightening, skin external preparation composition according to any one of claims 1 to 4. A skin external composition for skin moisturizing, skin external preparation composition according to any one of claims 1 to 4. Boil or steam the washed and dried natural product for 30 minutes to 2 hours;
Cooling the boiled or steamed natural product at room temperature for 30 minutes to 1 hour;
Wrapping or covering the cooled natural product with medicinal flowers, putting it in an unglazed pottery, and fermenting at room temperature in the shade for 4-7 days,
And a step of removing medicinal flowers from the fermented natural product for extraction. The method for producing a wrapping fermented extract according to claim 9, wherein the medicinal flower is at least one selected from the group consisting of chrysanthemums, gold and silver flowers, kiso flowers, kobushi, and lotus flowers . The natural product is beans, bitter rind, mung beans, solitary, bashken, bon bonsai, tang, mulberry leaves, lotus seeds, gokahide, tsumerengue, dogbill, dragon gall, longan grass, evening primrose, beneficial mother grass, carrot , Chen Chen, Red cabbage, Mongkok, Makiko, Shingoka, Mikoko, Kawamata, Uchiwadokoro, Tianshan Snow Lotus, Aoi, Kusanagi, Seisoushi, Earthen, Kusanem, Genokosho, Red Ginseng, and The method for producing a packaged fermented extract according to claim 9, wherein the method is one or more selected from the group consisting of mena fir .