JP6047309B2 - 抗腫瘍剤 - Google Patents

抗腫瘍剤 Download PDF

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Publication number
JP6047309B2
JP6047309B2 JP2012121422A JP2012121422A JP6047309B2 JP 6047309 B2 JP6047309 B2 JP 6047309B2 JP 2012121422 A JP2012121422 A JP 2012121422A JP 2012121422 A JP2012121422 A JP 2012121422A JP 6047309 B2 JP6047309 B2 JP 6047309B2
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Japan
Prior art keywords
compound
och
ddd
nmr
mannopyranoside
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Expired - Fee Related
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JP2012121422A
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English (en)
Japanese (ja)
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JP2013237659A5 (https=
JP2013237659A (ja
Inventor
麗子 杉浦
麗子 杉浦
修 村岡
修 村岡
望 筒井
望 筒井
綾子 喜多
綾子 喜多
樹 久能
樹 久能
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Kindai University
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Kindai University
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Priority to JP2012121422A priority Critical patent/JP6047309B2/ja
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Publication of JP2013237659A5 publication Critical patent/JP2013237659A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012121422A 2011-05-27 2012-05-28 抗腫瘍剤 Expired - Fee Related JP6047309B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012121422A JP6047309B2 (ja) 2011-05-27 2012-05-28 抗腫瘍剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011119797 2011-05-27
JP2011119797 2011-05-27
JP2012097198 2012-04-20
JP2012097198 2012-04-20
JP2012121422A JP6047309B2 (ja) 2011-05-27 2012-05-28 抗腫瘍剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016200463A Division JP6307138B2 (ja) 2011-05-27 2016-10-11 新規糖脂質グリコシド化合物およびその製造方法

Publications (3)

Publication Number Publication Date
JP2013237659A JP2013237659A (ja) 2013-11-28
JP2013237659A5 JP2013237659A5 (https=) 2014-04-10
JP6047309B2 true JP6047309B2 (ja) 2016-12-21

Family

ID=47259250

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012121422A Expired - Fee Related JP6047309B2 (ja) 2011-05-27 2012-05-28 抗腫瘍剤
JP2016200463A Expired - Fee Related JP6307138B2 (ja) 2011-05-27 2016-10-11 新規糖脂質グリコシド化合物およびその製造方法

Family Applications After (1)

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JP2016200463A Expired - Fee Related JP6307138B2 (ja) 2011-05-27 2016-10-11 新規糖脂質グリコシド化合物およびその製造方法

Country Status (5)

Country Link
US (1) US9828406B2 (https=)
EP (1) EP2716293B1 (https=)
JP (2) JP6047309B2 (https=)
CN (1) CN103608019B (https=)
WO (1) WO2012165394A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017036311A (ja) * 2011-05-27 2017-02-16 学校法人近畿大学 新規糖脂質グリコシド化合物およびその製造方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105384785B (zh) * 2015-11-24 2018-06-19 中国人民解放军第二军医大学 含有半乳糖类脂肪酸衍生物的制备方法及其在医药领域的应用
US12257214B2 (en) 2021-06-02 2025-03-25 The Charlotte Mecklenburg Hospital Authority Compositions and methods comprising deoxy-pentitols

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0474590A3 (en) * 1990-08-13 1993-04-21 Ciba-Geigy Ag Taurine derivatives, process for their preparation and their use
AU683026B2 (en) 1992-10-22 1997-10-30 Kirin Pharma Kabushiki Kaisha Novel shingoglycolipid and use thereof
US6153736A (en) 1995-09-27 2000-11-28 The Liposome Company, Inc. Modified ether glyceroglycolipids
DE19802450A1 (de) * 1998-01-23 1999-07-29 Hoechst Marion Roussel De Gmbh Ustilipide, Verfahren zu deren Herstellung sowie deren Verwendung
DE60003794T2 (de) 1999-02-26 2004-06-17 Toyo Suisan Kaisha, Ltd. Sulforhamnosylacylglycerin-derivate und ihre verwendung als medikamente
GB0025437D0 (en) * 2000-10-17 2000-11-29 Unilever Plc Esters
DE10135098B4 (de) * 2001-07-11 2004-05-13 Schering Ag Verfahren zur Herstellung von peracylierten 1-O-Glycosiden
JP4370591B2 (ja) * 2001-07-31 2009-11-25 独立行政法人産業技術総合研究所 リポソームおよびそれからなる細胞への物質導入担体
JP2006504752A (ja) 2002-10-15 2006-02-09 ロレアル 乾燥皮膚の治療及び／又は予防における脂肪酸のアミド又は糖とのエステルの使用
JP4858946B2 (ja) * 2006-01-10 2012-01-18 独立行政法人産業技術総合研究所 乳化剤又は可溶化剤
GB0614034D0 (en) * 2006-07-14 2006-08-23 Iqur Ltd Antiviral compounds
JP5145540B2 (ja) * 2007-04-12 2013-02-20 独立行政法人産業技術総合研究所 マンノシルアルジトールリピッド及びその製造方法
JP5344274B2 (ja) 2007-11-22 2013-11-20 東洋紡株式会社 新規マンノシルエリスリトールリピッドおよびその製造方法
WO2011112889A2 (en) 2010-03-12 2011-09-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services β-MANNOSYLCERAMIDE AND STIMULATION OF NKT CELL ANTI-TUMOR IMMUNITY
US9828406B2 (en) * 2011-05-27 2017-11-28 Kinki University Antitumor agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017036311A (ja) * 2011-05-27 2017-02-16 学校法人近畿大学 新規糖脂質グリコシド化合物およびその製造方法

Also Published As

Publication number Publication date
CN103608019B (zh) 2017-02-15
JP6307138B2 (ja) 2018-04-04
US20140121175A1 (en) 2014-05-01
EP2716293A4 (en) 2015-03-18
EP2716293A1 (en) 2014-04-09
JP2017036311A (ja) 2017-02-16
EP2716293B1 (en) 2017-09-06
JP2013237659A (ja) 2013-11-28
CN103608019A (zh) 2014-02-26
WO2012165394A1 (ja) 2012-12-06
US9828406B2 (en) 2017-11-28

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