JP2013237659A5

JP2013237659A5 -

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Publication number: JP2013237659A5
Authority: JP; Japan
Prior art keywords: compound; och; ddd; nmr; mannopyranoside
Prior art date: 2012-05-28
Legal status : Granted

Application number

JP2012121422A

Other languages

English (en)

Japanese (ja)

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JP6047309B2 (ja

JP2013237659A (ja

Filing date

2012-05-28

Publication date

2014-04-10

2012-05-28 Application filed filed Critical

2012-05-28 Priority to JP2012121422A priority Critical patent/JP6047309B2/ja

2012-05-28 Priority claimed from JP2012121422A external-priority patent/JP6047309B2/ja

2013-11-28 Publication of JP2013237659A publication Critical patent/JP2013237659A/ja

2014-04-10 Publication of JP2013237659A5 publication Critical patent/JP2013237659A5/ja

2016-12-21 Application granted granted Critical

2016-12-21 Publication of JP6047309B2 publication Critical patent/JP6047309B2/ja

Status Expired - Fee Related legal-status Critical Current

2032-05-28 Anticipated expiration legal-status Critical

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-1 glycolipid glycoside compound Chemical class 0.000 claims description 331
229930182470 glycoside Natural products 0.000 claims description 76
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239000002246 antineoplastic agent Substances 0.000 claims description 38
229930186217 Glycolipid Natural products 0.000 claims description 28
125000002252 acyl group Chemical group 0.000 claims description 24
125000004432 carbon atom Chemical group C* 0.000 claims description 23
PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 17
239000004480 active ingredient Substances 0.000 claims description 13
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 12
150000003839 salts Chemical class 0.000 claims description 12
229910052799 carbon Inorganic materials 0.000 claims description 5
150000001875 compounds Chemical class 0.000 description 465
238000005481 NMR spectroscopy Methods 0.000 description 224
238000004519 manufacturing process Methods 0.000 description 190
239000011734 sodium Substances 0.000 description 90
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 57
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238000004992 fast atom bombardment mass spectroscopy Methods 0.000 description 39
238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 33
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JP2012121422A 2011-05-27 2012-05-28 抗腫瘍剤 Expired - Fee Related JP6047309B2 (ja)