JP5885664B2 - スクリーニング法 - Google Patents

スクリーニング法 Download PDF

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JP5885664B2
JP5885664B2 JP2012531087A JP2012531087A JP5885664B2 JP 5885664 B2 JP5885664 B2 JP 5885664B2 JP 2012531087 A JP2012531087 A JP 2012531087A JP 2012531087 A JP2012531087 A JP 2012531087A JP 5885664 B2 JP5885664 B2 JP 5885664B2
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binding
antibody
binding affinity
rate parameter
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JP2013506140A5 (https=
JP2013506140A (ja
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マーク レスリー ホワイト
マーク レスリー ホワイト
マリナ ローエル
マリナ ローエル
ジョン コービン
ジョン コービン
ロバート バウアー
ロバート バウアー
ダニエル ベディンガー
ダニエル ベディンガー
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ゾーマ テクノロジー リミテッド
ゾーマ テクノロジー リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012531087A 2009-09-25 2010-09-24 スクリーニング法 Active JP5885664B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24607909P 2009-09-25 2009-09-25
US61/246,079 2009-09-25
US30632410P 2010-02-19 2010-02-19
US61/306,324 2010-02-19
PCT/US2010/050312 WO2011038301A2 (en) 2009-09-25 2010-09-24 Screening methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015196371A Division JP2016048240A (ja) 2009-09-25 2015-10-02 スクリーニング法

Publications (3)

Publication Number Publication Date
JP2013506140A JP2013506140A (ja) 2013-02-21
JP2013506140A5 JP2013506140A5 (https=) 2013-11-07
JP5885664B2 true JP5885664B2 (ja) 2016-03-15

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JP2012531087A Active JP5885664B2 (ja) 2009-09-25 2010-09-24 スクリーニング法
JP2015196371A Pending JP2016048240A (ja) 2009-09-25 2015-10-02 スクリーニング法

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JP2015196371A Pending JP2016048240A (ja) 2009-09-25 2015-10-02 スクリーニング法

Country Status (7)

Country Link
US (2) US9885711B2 (https=)
EP (2) EP2480888B1 (https=)
JP (2) JP5885664B2 (https=)
CN (1) CN102597775A (https=)
AU (1) AU2010298036B2 (https=)
CA (1) CA2772945A1 (https=)
WO (1) WO2011038301A2 (https=)

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RU2016119052A3 (en) 2013-10-17 2018-09-10 Arsanis Biosciences Gmbh Cross-reactive Staphylococcus aureus antibody sequences
WO2016001810A1 (en) 2014-07-01 2016-01-07 Pfizer Inc. Bispecific heterodimeric diabodies and uses thereof
MA40609B1 (fr) * 2014-09-05 2020-05-29 Janssen Pharmaceutica Nv Agents de liaison cd123 et leurs utilisations
CN107111691B (zh) 2014-10-27 2021-01-26 阿卜杜拉国王科技大学 识别配体-蛋白质结合位点的方法和系统
US10711067B2 (en) 2015-03-03 2020-07-14 Xoma (Us) Llc Treatment of post-prandial hyperinsulinemia and hypoglycemia after bariatric surgery
HK1252675A1 (zh) 2015-06-12 2019-05-31 Alector Llc 抗cd33抗体及其使用方法
AU2016276981B2 (en) 2015-06-12 2022-10-06 Alector Llc Anti-CD33 antibodies and methods of use thereof
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BR112019023789A2 (pt) 2017-08-03 2020-07-28 Alector Llc anticorpos anti-cd33 e métodos de uso dos mesmos
CN108490178B (zh) * 2018-02-13 2019-08-30 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 用于npc诊断及预后预测的标志物及其应用
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CN119841953A (zh) 2018-06-08 2025-04-18 艾利妥 抗siglec-7抗体及其使用方法
CR20210155A (es) 2018-08-31 2021-05-10 Alector Llc Anticuerpos anti-cd33 y métodos para usarlos
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CN109991168B (zh) * 2019-05-05 2021-09-07 韩山师范学院 一种可产生圆二色性的平面微纳结构
CN112111013A (zh) * 2019-06-22 2020-12-22 南京北恒生物科技有限公司 一种靶向claudin 18.2的通用型嵌合抗原受体T细胞、构建方法及其用途
CN111650368B (zh) * 2020-02-14 2024-02-02 北京纳百生物科技有限公司 一种免疫胶体金均相标记用受体分散剂及其应用
CN111443209B (zh) * 2020-03-26 2022-12-20 中国中医科学院医学实验中心 一种筛选非激动剂型PPARγ配体的方法
WO2023081898A1 (en) 2021-11-08 2023-05-11 Alector Llc Soluble cd33 as a biomarker for anti-cd33 efficacy
CN121264104A (zh) * 2023-08-08 2026-01-02 乐天移动株式会社 层（l1/l2）触发的移动性（ltm）期间的定时提前管理
CN117003882B (zh) * 2023-10-07 2023-12-12 北京丹大生物技术有限公司 一种用于检测戈利木单抗的杂交瘤细胞株组合和抗体组合及其应用
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