JP5869677B2 - トランスサイレチン解離阻害剤の固体形態 - Google Patents
トランスサイレチン解離阻害剤の固体形態 Download PDFInfo
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- JP5869677B2 JP5869677B2 JP2014530354A JP2014530354A JP5869677B2 JP 5869677 B2 JP5869677 B2 JP 5869677B2 JP 2014530354 A JP2014530354 A JP 2014530354A JP 2014530354 A JP2014530354 A JP 2014530354A JP 5869677 B2 JP5869677 B2 JP 5869677B2
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
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| JPH0250258A (ja) * | 1988-08-11 | 1990-02-20 | Nec Corp | ベクトル処理装置 |
| JP2016128444A (ja) * | 2011-09-16 | 2016-07-14 | ファイザー・インク | トランスサイレチン解離阻害剤の固体形態 |
| US12473063B2 (en) | 2020-09-23 | 2025-11-18 | Pierre Berger | Device for connection between a canvas and a rail |
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| EP2764866A1 (en) | 2013-02-07 | 2014-08-13 | IP Gesellschaft für Management mbH | Inhibitors of nedd8-activating enzyme |
| SG11201700958YA (en) * | 2014-09-08 | 2017-03-30 | Pfizer | Crystalline solid forms of 6-carboxy-2-(3,5-dichlorophenyl)-benzoxazole |
| CN107344927A (zh) | 2016-05-05 | 2017-11-14 | 苏州晶云药物科技有限公司 | Tafamidis葡甲胺盐的晶型E及其制备方法和用途 |
| GB2571950A (en) | 2018-03-13 | 2019-09-18 | Azad Pharma Ag | New polymorph and new path to synthesize tafamidis |
| US12268669B2 (en) | 2018-12-20 | 2025-04-08 | Pfizer Inc. | Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent |
| WO2020207753A1 (en) | 2019-04-11 | 2020-10-15 | Inke, S.A. | Process for preparing 1-deoxy-1-methylamino-d-glucitol 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylate |
| US12391656B2 (en) | 2019-05-16 | 2025-08-19 | Assia Chemical Industries Ltd. | Solid state forms of Tafamidis and salts thereof |
| BR112021024151A2 (pt) * | 2019-05-31 | 2022-02-08 | Plex Pharmaceuticals Inc | Agentes farmacológicos para tratamento de doenças de agregação de proteínas do olho |
| WO2021019448A1 (en) * | 2019-08-01 | 2021-02-04 | Honour (R&D) | Process for the preparation of transthyretin dissociation inhibitor |
| JP2023503833A (ja) | 2019-11-15 | 2023-02-01 | ▲蘇▼州科睿思制▲葯▼有限公司 | タファミジスの結晶形及びその調製方法及びその使用 |
| MX2022007787A (es) * | 2019-12-20 | 2022-07-19 | Pfizer Ireland Pharmaceuticals | Proceso eficiente para elaborar derivados de 6-carboxi-benzoxazol. |
| WO2021232619A1 (zh) * | 2020-05-19 | 2021-11-25 | 苏州科睿思制药有限公司 | 一种他发米帝司游离酸的晶型及其制备方法和用途 |
| WO2022009221A1 (en) * | 2020-07-04 | 2022-01-13 | Nuray Chemicals Private Limited | Solid state forms of 6-carboxy-2-(3, 5-dichlorophenyl)-benzoxazole of formula-i and pharmaceutically acceptable salts thereof |
| US20230391737A1 (en) * | 2020-10-19 | 2023-12-07 | Glenmark Life Sciences Limited | Process for preparation of tafamidis and salts thereof |
| WO2022112919A1 (en) | 2020-11-25 | 2022-06-02 | Pfizer Inc. | (aza)benzothiazolyl substituted pyrazole compounds |
| EP4083027A1 (en) | 2021-04-26 | 2022-11-02 | Química Sintética, S.A. | A solid state form of tafamidis and a process for its preparation |
| WO2023020762A1 (en) | 2021-08-16 | 2023-02-23 | Synthon B.V. | Crystalline forms of tafamidis nicotinamide adduct |
| EP4433461A1 (en) | 2021-11-17 | 2024-09-25 | Teva Pharmaceuticals International GmbH | Solid state form of tafamidis |
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| DE602336C (de) | 1933-03-09 | 1934-09-06 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von Kuepenfarbstoffen der Anthrachinonreihe |
| US3551433A (en) | 1967-06-21 | 1970-12-29 | Us Army | Preparation of 4-phenyl-4-acyloxypiperidine |
| US3551443A (en) | 1968-10-30 | 1970-12-29 | Ciba Ltd | 2-phenylbenzoxazole derivatives |
| USRE29608E (en) | 1972-05-18 | 1978-04-11 | Lilly Industries Limited | Benzoxazole derivatives |
| DE2314238A1 (de) | 1973-03-22 | 1974-09-26 | Henkel & Cie Gmbh | Neue 2-(tetrazol-5'-yl)-benzoxazole, deren herstellung sowie verwendung als entzuendungshemmer in kosmetischen praeparationen |
| GB1488003A (en) * | 1973-10-23 | 1977-10-05 | Lilly Industries Ltd | 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals |
| US4025636A (en) | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2-(Optionally substituted)phenyl-5 or 6-substituted benzoxazoles |
| US4025637A (en) | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2,5 OR 2,6 Disubstituted benzoxazoles |
| DE2619547A1 (de) | 1976-05-04 | 1977-11-24 | Dynamit Nobel Ag | Verfahren zur herstellung von 2-aryl- benzoxazolen und 2-aryl-benzthiazolen |
| US4416892A (en) | 1981-04-23 | 1983-11-22 | Lilly Industries Limited | Method of treating hypersensitivity disease with benzoxazole derivatives |
| US5033252A (en) | 1987-12-23 | 1991-07-23 | Entravision, Inc. | Method of packaging and sterilizing a pharmaceutical product |
| US5052558A (en) | 1987-12-23 | 1991-10-01 | Entravision, Inc. | Packaged pharmaceutical product |
| DE4011106A1 (de) | 1990-04-06 | 1991-10-10 | Bayer Ag | Neue heterocyclisch substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| US5254692A (en) | 1990-04-06 | 1993-10-19 | Bayer Aktiengesellschaft | 2,6-dialkyl-4-(benzothiazol- or benzoxazol-7-yl)-1,4-dihydropyridines |
| US5037842A (en) | 1990-06-05 | 1991-08-06 | Pfizer Inc. | Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents |
| CA2051518A1 (en) | 1990-10-01 | 1992-04-02 | Robert J. Perry | Synthesis of heterocyclic compounds |
| CH681806A5 (OSRAM) | 1991-03-19 | 1993-05-28 | Ciba Geigy Ag | |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0250258A (ja) * | 1988-08-11 | 1990-02-20 | Nec Corp | ベクトル処理装置 |
| JP2016128444A (ja) * | 2011-09-16 | 2016-07-14 | ファイザー・インク | トランスサイレチン解離阻害剤の固体形態 |
| US12473063B2 (en) | 2020-09-23 | 2025-11-18 | Pierre Berger | Device for connection between a canvas and a rail |
Also Published As
| Publication number | Publication date |
|---|---|
| US9249112B2 (en) | 2016-02-02 |
| TW201516039A (zh) | 2015-05-01 |
| TW201315720A (zh) | 2013-04-16 |
| RU2014109676A (ru) | 2015-10-27 |
| CA2847293C (en) | 2017-03-28 |
| US20150031735A1 (en) | 2015-01-29 |
| HK1197239A1 (zh) | 2015-01-09 |
| AU2012310157A1 (en) | 2014-04-03 |
| US20160185739A1 (en) | 2016-06-30 |
| RU2586330C2 (ru) | 2016-06-10 |
| JP2014526498A (ja) | 2014-10-06 |
| IL231472A0 (en) | 2014-04-30 |
| TWI538909B (zh) | 2016-06-21 |
| ZA201401202B (en) | 2016-01-27 |
| KR20140054231A (ko) | 2014-05-08 |
| TWI476185B (zh) | 2015-03-11 |
| SG2014013270A (en) | 2014-05-29 |
| CN103781770A (zh) | 2014-05-07 |
| MX2014003043A (es) | 2015-02-05 |
| JP2016128444A (ja) | 2016-07-14 |
| CA2847293A1 (en) | 2013-03-21 |
| NZ621194A (en) | 2016-02-26 |
| CN103781770B (zh) | 2016-04-13 |
| WO2013038351A1 (en) | 2013-03-21 |
| EP2755961A1 (en) | 2014-07-23 |
| BR112014005810A2 (pt) | 2017-03-28 |
| AU2012310157B2 (en) | 2015-11-12 |
| AR088755A1 (es) | 2014-07-02 |
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