JP5867950B2 - 癒着防止剤 - Google Patents

癒着防止剤 Download PDF

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Publication number
JP5867950B2
JP5867950B2 JP2015514792A JP2015514792A JP5867950B2 JP 5867950 B2 JP5867950 B2 JP 5867950B2 JP 2015514792 A JP2015514792 A JP 2015514792A JP 2015514792 A JP2015514792 A JP 2015514792A JP 5867950 B2 JP5867950 B2 JP 5867950B2
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mono
glycerol
mmol
adhesion
erythritol
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JPWO2014178256A1 (ja
Inventor
田畑　泰彦
泰彦 田畑
健次郎 平井
健次郎 平井
一郎 土黒
一郎 土黒
昌久 田能村
昌久 田能村
紗也香 森
紗也香 森
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FARNEX INCORPORATED
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FARNEX INCORPORATED
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0076—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
JP2015514792A 2013-05-01 2014-04-02 癒着防止剤 Active JP5867950B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2015514792A JP5867950B2 (ja) 2013-05-01 2014-04-02 癒着防止剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2013096499 2013-05-01
JP2013096499 2013-05-01
PCT/JP2014/059785 WO2014178256A1 (ja) 2013-05-01 2014-04-02 癒着防止剤
JP2015514792A JP5867950B2 (ja) 2013-05-01 2014-04-02 癒着防止剤

Related Child Applications (1)

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JP2015255781A Division JP2016040339A (ja) 2013-05-01 2015-12-28 癒着防止剤

Publications (2)

Publication Number Publication Date
JP5867950B2 true JP5867950B2 (ja) 2016-02-24
JPWO2014178256A1 JPWO2014178256A1 (ja) 2017-02-23

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JP2015514792A Active JP5867950B2 (ja) 2013-05-01 2014-04-02 癒着防止剤
JP2015255781A Ceased JP2016040339A (ja) 2013-05-01 2015-12-28 癒着防止剤

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Country Status (5)

Country Link
US (1) US20160067208A1 (https=)
EP (1) EP2992910A4 (https=)
JP (2) JP5867950B2 (https=)
CN (1) CN105358190A (https=)
WO (1) WO2014178256A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016121962A1 (ja) * 2015-01-30 2016-08-04 株式会社ファルネックス メラニン産生抑制剤
KR101784863B1 (ko) * 2015-09-03 2017-10-13 (주)진우바이오 히알루론산염이 코팅된 고 기능성 봉합사의 제조방법 및 이로부터 제조된 고 기능성 봉합사
JP6721907B2 (ja) * 2015-12-18 2020-07-15 メディギア・インターナショナル株式会社 生体分解性腫瘍封止剤
WO2018043731A1 (ja) * 2016-09-05 2018-03-08 株式会社ファルネックス 油分を含むエマルションを用いた癒着防止剤
EP3701975B1 (en) 2017-10-25 2023-12-27 Takeo Tanaka Biodegradable and biometabolic tumor sealant
WO2020050423A1 (ja) 2018-09-07 2020-03-12 株式会社ファルネックス 非ラメラ液晶形成脂質を含む外用剤
EP4098281A4 (en) * 2020-01-27 2024-03-20 Farnex Incorporated HIGH SAFE NONLAMELLAR LIQUID CRYSTAL FORMING COMPOSITION
TWI777516B (zh) * 2020-04-24 2022-09-11 博唯弘展生技股份有限公司 用於預防組織沾黏的溫度敏感組成物及其應用
CN111772802B (zh) * 2020-06-19 2023-09-19 南昌大学第二附属医院 一种疏血型手套的制作方法
KR102388506B1 (ko) * 2021-06-14 2022-04-20 (주)씨앤엘디 유착방지용 조성물
EP4378452A4 (en) * 2021-07-27 2025-07-23 Farnex Incorporated NON-LAMELLAR LIQUID CRYSTAL FORMING COMPOSITION AND ITS USE

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028946A (ja) * 1983-07-28 1985-02-14 Kao Corp テルペンアルコ−ルのジグリセリンアルキルエ−テル及びこれを含有する化粧料
JPS6028945A (ja) * 1983-07-25 1985-02-14 Kao Corp テルペンアルコ−ルのグリセリルエ−テル及びこれを含有する化粧料
JP2004059470A (ja) * 2002-07-26 2004-02-26 Kanebo Ltd 養毛料
WO2006043705A1 (ja) * 2004-10-19 2006-04-27 National Institute Of Advanced Industrial Scienceand Technology Ｉｉ型キュービック液晶組成物
WO2011078383A1 (ja) * 2009-12-25 2011-06-30 株式会社サイトパスファインダー 低粘度液晶化合物
JP2012017318A (ja) * 2010-06-07 2012-01-26 Nikko Chemical Co Ltd 液晶及びそれを含有する皮膚外用剤

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JPS5826331B2 (ja) 1974-09-02 1983-06-02 株式会社クラレ 立体規制されたファルネシル酢酸エステルの製造方法
JPS5826330B2 (ja) 1974-09-02 1983-06-02 株式会社クラレ 立体規制されたファルネシル酢酸エステルの製造方法
JPS5820948B2 (ja) 1974-09-02 1983-04-26 株式会社クラレ デルタ ４ ，デルタ ８− トランスフアルネシルサクサン マタハ ソノエステルルイ ノ セイゾウホウ
JPS5826328B2 (ja) 1974-09-02 1983-06-02 株式会社クラレ リツタイキセイサレタ フアルネシルサクサン マタハ ソノエステル ノ セイゾウホウホウ
JPS5822457B2 (ja) 1974-09-02 1983-05-09 株式会社クラレ デルタ ４ ，デルタ ８− トランスフアルネシルサクサン マタハ ソノエステルルイ ノ セイゾウホウホウ
JP4566189B2 (ja) 2004-03-15 2010-10-20 テルモ株式会社 癒着防止材
JP4617477B2 (ja) * 2004-10-19 2011-01-26 独立行政法人産業技術総合研究所 Ｉｉ型キュービック液晶組成物にリソソーム酵素を包埋した複合体
KR101245022B1 (ko) 2005-01-21 2013-03-19 카무러스 에이비 약제학적 지질 조성물
GB0625965D0 (en) * 2006-12-23 2007-02-07 Renovo Ltd Medicaments for wound healing
JP5406281B2 (ja) 2009-04-17 2014-02-05 帝人株式会社 多糖類誘導体およびそのハイドロゲル
JP5858732B2 (ja) 2011-10-31 2016-02-10 エア・ウォーター防災株式会社 ガス供給ソケット

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6028945A (ja) * 1983-07-25 1985-02-14 Kao Corp テルペンアルコ−ルのグリセリルエ−テル及びこれを含有する化粧料
JPS6028946A (ja) * 1983-07-28 1985-02-14 Kao Corp テルペンアルコ−ルのジグリセリンアルキルエ−テル及びこれを含有する化粧料
JP2004059470A (ja) * 2002-07-26 2004-02-26 Kanebo Ltd 養毛料
WO2006043705A1 (ja) * 2004-10-19 2006-04-27 National Institute Of Advanced Industrial Scienceand Technology Ｉｉ型キュービック液晶組成物
WO2011078383A1 (ja) * 2009-12-25 2011-06-30 株式会社サイトパスファインダー 低粘度液晶化合物
JP2012017318A (ja) * 2010-06-07 2012-01-26 Nikko Chemical Co Ltd 液晶及びそれを含有する皮膚外用剤

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* Cited by examiner, † Cited by third party
Title
JPN6014025646; Ｂｉｏｏｒｇａｎｉｃ　＆　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ　Ｌｅｔｔｅｒｓ Ｖｏｌ．１３，Ｎｏ．１, 2003, ｐ４３-４６ *
JPN6014025648; Ｔｅｔｒａｈｅｄｒｏｎ：　Ａｓｙｍｍｅｔｒｙ Ｖｏｌ．１０，Ｎｏ．７, 1999, ｐ１２６３-１２７３ *
JPN6014025651; Ｊｏｕｒｎａｌ　ｏｆ　Ｂｉｏｌｏｇｉｃａｌ　Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．２６６，Ｎｏ．１１, 1991, ｐ６６７４-６６７７ *

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Publication number Publication date
CN105358190A (zh) 2016-02-24
JPWO2014178256A1 (ja) 2017-02-23
EP2992910A1 (en) 2016-03-09
JP2016040339A (ja) 2016-03-24
US20160067208A1 (en) 2016-03-10
EP2992910A4 (en) 2016-12-07
WO2014178256A1 (ja) 2014-11-06

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