JP5805088B2 - 遺伝子発現を阻害する組成物およびその使用 - Google Patents
遺伝子発現を阻害する組成物およびその使用 Download PDFInfo
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- JP5805088B2 JP5805088B2 JP2012526977A JP2012526977A JP5805088B2 JP 5805088 B2 JP5805088 B2 JP 5805088B2 JP 2012526977 A JP2012526977 A JP 2012526977A JP 2012526977 A JP2012526977 A JP 2012526977A JP 5805088 B2 JP5805088 B2 JP 5805088B2
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| KR101141544B1 (ko) | 2009-03-13 | 2012-05-03 | 한국과학기술원 | 에스아이알엔에이 다중 접합체 및 이의 제조방법 |
| US20130079505A1 (en) * | 2010-03-24 | 2013-03-28 | Mirrx Therapeutics A/S | Bivalent antisense oligonucleotides |
| EP2609198B8 (en) | 2010-08-24 | 2018-03-28 | Sirna Therapeutics, Inc. | SINGLE-STRANDED RNAi AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER |
| US8877722B2 (en) * | 2011-03-25 | 2014-11-04 | Idera Pharmaceuticals, Inc. | Compositions for inhibiting gene expression and uses thereof |
| EP3533873A1 (en) | 2011-09-14 | 2019-09-04 | Translate Bio MA, Inc. | Multimeric oligonucleotide compounds |
| PE20142362A1 (es) | 2011-11-18 | 2015-01-30 | Alnylam Pharmaceuticals Inc | Agentes de iarn, composiciones y metodos de uso de los mismos para tratar enfermedades asociadas con transtiretina (ttr) |
| DK3366775T4 (da) | 2011-11-18 | 2025-10-27 | Alnylam Pharmaceuticals Inc | Modificerede rnai-midler |
| WO2013169382A1 (en) * | 2012-05-07 | 2013-11-14 | DePuy Synthes Products, LLC | Methods and devices for treating intervertebral disc disease |
| US9255154B2 (en) | 2012-05-08 | 2016-02-09 | Alderbio Holdings, Llc | Anti-PCSK9 antibodies and use thereof |
| ITNA20120046A1 (it) | 2012-08-02 | 2014-02-03 | No Self S R L | Uso di acidi nucleici di sistemi biologici parassiti, patogeni e infestanti per l'inibizione e/o controllo degli stessi sistemi |
| WO2014022739A2 (en) | 2012-08-03 | 2014-02-06 | Alnylam Pharmaceuticals, Inc. | Modified rnai agents |
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| TW201607559A (zh) | 2014-05-12 | 2016-03-01 | 阿尼拉製藥公司 | 治療ｓｅｒｐｉｎｃ１相關疾患之方法和組成物 |
| EA201692370A1 (ru) | 2014-05-22 | 2017-03-31 | Элнилэм Фармасьютикалз, Инк. | КОМПОЗИЦИИ иРНК АНГИОТЕНЗИНОГЕНА (AGT) И СПОСОБЫ ИХ ИСПОЛЬЗОВАНИЯ |
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| CN106794256B (zh) | 2014-08-19 | 2021-04-30 | 西北大学 | 蛋白质/寡核苷酸核-壳纳米颗粒治疗剂 |
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| EP2179061B1 (en) * | 2007-08-15 | 2012-10-03 | Idera Pharmaceuticals, Inc. | Toll like receptor modulators |
| MX2011008383A (es) * | 2009-02-10 | 2011-09-06 | Idera Pharmaceuticals Inc | Agonistas basados en acido ribonucleico sintetico de receptor 7 tipo toll. |
-
2010
- 2010-08-26 PL PL10749570T patent/PL2470656T3/pl unknown
- 2010-08-26 HU HUE10749570A patent/HUE026020T2/en unknown
- 2010-08-26 DK DK10749570.7T patent/DK2470656T3/da active
- 2010-08-26 EP EP10749570.7A patent/EP2470656B1/en active Active
- 2010-08-26 CA CA2772352A patent/CA2772352A1/en not_active Abandoned
- 2010-08-26 ES ES15165966.1T patent/ES2646097T3/es active Active
- 2010-08-26 CN CN201410573396.9A patent/CN104673795A/zh active Pending
- 2010-08-26 ES ES10749570.7T patent/ES2538347T3/es active Active
- 2010-08-26 US US12/869,209 patent/US8431544B1/en not_active Expired - Fee Related
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- 2010-08-26 JP JP2012526977A patent/JP5805088B2/ja not_active Expired - Fee Related
- 2010-08-26 SI SI201030947T patent/SI2470656T1/sl unknown
- 2010-08-26 PT PT107495707T patent/PT2470656E/pt unknown
- 2010-08-26 EP EP15165966.1A patent/EP2960333B1/en not_active Not-in-force
- 2010-08-26 EP EP17190602.7A patent/EP3272870A1/en not_active Withdrawn
- 2010-08-26 CN CN201080048450.8A patent/CN102712926B/zh not_active Expired - Fee Related
- 2010-08-26 US US12/869,185 patent/US20110082186A1/en not_active Abandoned
- 2010-08-26 WO PCT/US2010/046781 patent/WO2011031520A1/en not_active Ceased
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2011
- 2011-03-02 US US13/038,924 patent/US20120016004A1/en not_active Abandoned
-
2015
- 2015-06-18 SM SM201500140T patent/SMT201500140B/xx unknown
- 2015-11-11 HK HK15111120.3A patent/HK1210223A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2646097T3 (es) | 2017-12-12 |
| WO2011031520A1 (en) | 2011-03-17 |
| JP2013507905A (ja) | 2013-03-07 |
| EP2470656A1 (en) | 2012-07-04 |
| EP2960333B1 (en) | 2017-10-04 |
| DK2470656T3 (da) | 2015-06-22 |
| US20120016004A1 (en) | 2012-01-19 |
| HUE026020T2 (en) | 2016-05-30 |
| US8431544B1 (en) | 2013-04-30 |
| HRP20150566T1 (hr) | 2015-07-17 |
| EP2470656B1 (en) | 2015-05-06 |
| CA2772352A1 (en) | 2011-03-17 |
| CN102712926B (zh) | 2015-04-29 |
| CN102712926A (zh) | 2012-10-03 |
| PL2470656T3 (pl) | 2015-08-31 |
| HK1210223A1 (en) | 2016-04-15 |
| EP2960333A1 (en) | 2015-12-30 |
| US20110082186A1 (en) | 2011-04-07 |
| SMT201500140B (it) | 2015-09-07 |
| PT2470656E (pt) | 2015-07-16 |
| EP3272870A1 (en) | 2018-01-24 |
| ES2538347T3 (es) | 2015-06-19 |
| CN104673795A (zh) | 2015-06-03 |
| SI2470656T1 (sl) | 2015-07-31 |
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