JP5778168B2 - 多環式化合物及びその使用方法 - Google Patents
多環式化合物及びその使用方法 Download PDFInfo
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- JP5778168B2 JP5778168B2 JP2012542219A JP2012542219A JP5778168B2 JP 5778168 B2 JP5778168 B2 JP 5778168B2 JP 2012542219 A JP2012542219 A JP 2012542219A JP 2012542219 A JP2012542219 A JP 2012542219A JP 5778168 B2 JP5778168 B2 JP 5778168B2
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- 0 CCC(***1)C1C(*)(CC(*)(*)N(*)*)***C**=C Chemical compound CCC(***1)C1C(*)(CC(*)(*)N(*)*)***C**=C 0.000 description 13
- PPLSPIZQQHAHBA-UHFFFAOYSA-N CNCC(CC1)c2c1[s]cc2 Chemical compound CNCC(CC1)c2c1[s]cc2 PPLSPIZQQHAHBA-UHFFFAOYSA-N 0.000 description 2
- RBIGKSZIQCTIJF-UHFFFAOYSA-N O=Cc1c[s]cc1 Chemical compound O=Cc1c[s]cc1 RBIGKSZIQCTIJF-UHFFFAOYSA-N 0.000 description 2
- TVYQEDUVSABWTO-UHFFFAOYSA-N Brc1c[s]c2c1CCCC2 Chemical compound Brc1c[s]c2c1CCCC2 TVYQEDUVSABWTO-UHFFFAOYSA-N 0.000 description 1
- XCMISAPCWHTVNG-UHFFFAOYSA-N Brc1c[s]cc1 Chemical compound Brc1c[s]cc1 XCMISAPCWHTVNG-UHFFFAOYSA-N 0.000 description 1
- XXGOWWQYQBPPPW-VHSXEESVSA-N C(C1)CN[C@@H]1[C@H]1OCCc2c1[s]cc2 Chemical compound C(C1)CN[C@@H]1[C@H]1OCCc2c1[s]cc2 XXGOWWQYQBPPPW-VHSXEESVSA-N 0.000 description 1
- HAEKJYLETBXYNG-UHFFFAOYSA-N C=[Br]c1c(CCO)cc[s]1 Chemical compound C=[Br]c1c(CCO)cc[s]1 HAEKJYLETBXYNG-UHFFFAOYSA-N 0.000 description 1
- SDLGTESLGIAYGB-UHFFFAOYSA-N CC(C)(C)OC(N(C)CC(CC1)c2c1[s]cc2)=O Chemical compound CC(C)(C)OC(N(C)CC(CC1)c2c1[s]cc2)=O SDLGTESLGIAYGB-UHFFFAOYSA-N 0.000 description 1
- HLFRLJXPKWUEDP-UHFFFAOYSA-N CC(C)(C)OC(NCC1OCCc([s]2)c1cc2I)=O Chemical compound CC(C)(C)OC(NCC1OCCc([s]2)c1cc2I)=O HLFRLJXPKWUEDP-UHFFFAOYSA-N 0.000 description 1
- BOOFCAWXWFFTOF-UHFFFAOYSA-N CC(C)(C)OC(NCC1OCCc2c1cc[s]2)=O Chemical compound CC(C)(C)OC(NCC1OCCc2c1cc[s]2)=O BOOFCAWXWFFTOF-UHFFFAOYSA-N 0.000 description 1
- NIBDYNBWJDEMKA-UHFFFAOYSA-N CC1(CN)OCCc2c1cc[s]2 Chemical compound CC1(CN)OCCc2c1cc[s]2 NIBDYNBWJDEMKA-UHFFFAOYSA-N 0.000 description 1
- CVPMWSNCBRQHGN-UHFFFAOYSA-N CC1C(C(CN)(CCC2)O)=C2SC1 Chemical compound CC1C(C(CN)(CCC2)O)=C2SC1 CVPMWSNCBRQHGN-UHFFFAOYSA-N 0.000 description 1
- JVKOMXUTXGBJFC-ONEGZZNKSA-N CCOC(/C=C/c1c[s]cc1)=O Chemical compound CCOC(/C=C/c1c[s]cc1)=O JVKOMXUTXGBJFC-ONEGZZNKSA-N 0.000 description 1
- ZUSSQACKXMCGFT-UHFFFAOYSA-N CCOC(CC(C[N+]([O-])=O)c1c[s]cc1)=O Chemical compound CCOC(CC(C[N+]([O-])=O)c1c[s]cc1)=O ZUSSQACKXMCGFT-UHFFFAOYSA-N 0.000 description 1
- CLSZRDFHZXZWKT-UHFFFAOYSA-N CCOC(CCCc1cc(C)c[s]1)O Chemical compound CCOC(CCCc1cc(C)c[s]1)O CLSZRDFHZXZWKT-UHFFFAOYSA-N 0.000 description 1
- PDORSSDXQVDSPF-UHFFFAOYSA-N CCOCNCC(CC1)c2c1[s]cc2 Chemical compound CCOCNCC(CC1)c2c1[s]cc2 PDORSSDXQVDSPF-UHFFFAOYSA-N 0.000 description 1
- HKJNETXKKFHFQI-UHFFFAOYSA-N CCc1cc(C(CN)CCCC2)c2[s]1 Chemical compound CCc1cc(C(CN)CCCC2)c2[s]1 HKJNETXKKFHFQI-UHFFFAOYSA-N 0.000 description 1
- UIZHRTSQGYHQBY-UHFFFAOYSA-N CCc1cc(C(CNC)CCCC2)c2[s]1 Chemical compound CCc1cc(C(CNC)CCCC2)c2[s]1 UIZHRTSQGYHQBY-UHFFFAOYSA-N 0.000 description 1
- WECLBGLNGIHXNA-UHFFFAOYSA-N CNCC(CCC1)c2c1[s]c(N)n2 Chemical compound CNCC(CCC1)c2c1[s]c(N)n2 WECLBGLNGIHXNA-UHFFFAOYSA-N 0.000 description 1
- APIGZRUGKPZFFI-UHFFFAOYSA-N CNCC1OCCCc2c1cc[s]2 Chemical compound CNCC1OCCCc2c1cc[s]2 APIGZRUGKPZFFI-UHFFFAOYSA-N 0.000 description 1
- HPGXWUUGOKBNNJ-UHFFFAOYSA-N CNCC1Oc2ccccc2-c2c1[s]cc2 Chemical compound CNCC1Oc2ccccc2-c2c1[s]cc2 HPGXWUUGOKBNNJ-UHFFFAOYSA-N 0.000 description 1
- HVXCGIPRXBJIRK-UHFFFAOYSA-N Cc1c[s]c(C=O)c1 Chemical compound Cc1c[s]c(C=O)c1 HVXCGIPRXBJIRK-UHFFFAOYSA-N 0.000 description 1
- VMANPYMZMLYRPY-UHFFFAOYSA-N NCC(CC1)c2c1[s]cc2 Chemical compound NCC(CC1)c2c1[s]cc2 VMANPYMZMLYRPY-UHFFFAOYSA-N 0.000 description 1
- AYTKKMCQQCDLET-UHFFFAOYSA-N NCC(CCC1)(c2c1[s]cc2)O Chemical compound NCC(CCC1)(c2c1[s]cc2)O AYTKKMCQQCDLET-UHFFFAOYSA-N 0.000 description 1
- JPULNNSJRQZWLJ-UHFFFAOYSA-N NCC(c1c[s]2)OCCc1c2Br Chemical compound NCC(c1c[s]2)OCCc1c2Br JPULNNSJRQZWLJ-UHFFFAOYSA-N 0.000 description 1
- XSJNRKCAVIWOGV-UHFFFAOYSA-N OCCc(cc[s]1)c1Br Chemical compound OCCc(cc[s]1)c1Br XSJNRKCAVIWOGV-UHFFFAOYSA-N 0.000 description 1
- YYPNNBPPDFTQFX-UHFFFAOYSA-N OCCc1c[s]cc1 Chemical compound OCCc1c[s]cc1 YYPNNBPPDFTQFX-UHFFFAOYSA-N 0.000 description 1
- VVOASXXDMVSWTK-UHFFFAOYSA-N [O-][N+](CC(CC(O)=O)c1c[s]cc1)=O Chemical compound [O-][N+](CC(CC(O)=O)c1c[s]cc1)=O VVOASXXDMVSWTK-UHFFFAOYSA-N 0.000 description 1
- BUWSEZUSGNBMJN-UHFFFAOYSA-N [O-][N+](CC(CC1=O)c2c1[s]cc2)=O Chemical compound [O-][N+](CC(CC1=O)c2c1[s]cc2)=O BUWSEZUSGNBMJN-UHFFFAOYSA-N 0.000 description 1
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- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26688009P | 2009-12-04 | 2009-12-04 | |
| US61/266,880 | 2009-12-04 | ||
| PCT/US2010/058884 WO2011069063A2 (en) | 2009-12-04 | 2010-12-03 | Multicyclic compounds and methods of use thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014253082A Division JP5710064B1 (ja) | 2009-12-04 | 2014-12-15 | 多環式化合物及びその使用方法 |
| JP2015136603A Division JP6005807B2 (ja) | 2009-12-04 | 2015-07-08 | 多環式化合物及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013512926A JP2013512926A (ja) | 2013-04-18 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2015227348A (ja) * | 2009-12-04 | 2015-12-17 | スノビオン プハルマセウトイカルス インコーポレイテッド | 多環式化合物及びその使用方法 |
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