JP5537347B2 - 粒子分析装置 - Google Patents

粒子分析装置 Download PDF

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Publication number
JP5537347B2
JP5537347B2 JP2010198593A JP2010198593A JP5537347B2 JP 5537347 B2 JP5537347 B2 JP 5537347B2 JP 2010198593 A JP2010198593 A JP 2010198593A JP 2010198593 A JP2010198593 A JP 2010198593A JP 5537347 B2 JP5537347 B2 JP 5537347B2
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Japan
Prior art keywords
light
optical system
light source
particles
cell
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Expired - Fee Related
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JP2010198593A
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English (en)
Japanese (ja)
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JP2011133460A (ja
JP2011133460A5 (enExample
Inventor
正継 小篠
寛征 小林
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Sysmex Corp
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Sysmex Corp
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Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Priority to JP2010198593A priority Critical patent/JP5537347B2/ja
Priority to US12/951,779 priority patent/US8772738B2/en
Priority to CN201010565424.4A priority patent/CN102156088B/zh
Priority to EP10193092.3A priority patent/EP2327977A3/en
Publication of JP2011133460A publication Critical patent/JP2011133460A/ja
Publication of JP2011133460A5 publication Critical patent/JP2011133460A5/ja
Application granted granted Critical
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0092—Monitoring flocculation or agglomeration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Computer Vision & Pattern Recognition (AREA)
JP2010198593A 2009-11-30 2010-09-06 粒子分析装置 Expired - Fee Related JP5537347B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2010198593A JP5537347B2 (ja) 2009-11-30 2010-09-06 粒子分析装置
US12/951,779 US8772738B2 (en) 2009-11-30 2010-11-22 Particle analyzing apparatus and particle imaging method
CN201010565424.4A CN102156088B (zh) 2009-11-30 2010-11-30 粒子分析仪及粒子拍摄方法
EP10193092.3A EP2327977A3 (en) 2009-11-30 2010-11-30 Particle analyzing apparatus and particle imaging method

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009272974 2009-11-30
JP2009272974 2009-11-30
JP2010198593A JP5537347B2 (ja) 2009-11-30 2010-09-06 粒子分析装置

Publications (3)

Publication Number Publication Date
JP2011133460A JP2011133460A (ja) 2011-07-07
JP2011133460A5 JP2011133460A5 (enExample) 2013-07-18
JP5537347B2 true JP5537347B2 (ja) 2014-07-02

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Family Applications (1)

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JP2010198593A Expired - Fee Related JP5537347B2 (ja) 2009-11-30 2010-09-06 粒子分析装置

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US (1) US8772738B2 (enExample)
EP (1) EP2327977A3 (enExample)
JP (1) JP5537347B2 (enExample)
CN (1) CN102156088B (enExample)

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JP6438319B2 (ja) * 2015-02-18 2018-12-12 アズビル株式会社 粒子検出装置
JP6557022B2 (ja) * 2015-02-18 2019-08-07 アズビル株式会社 粒子検出装置
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US10060847B2 (en) * 2015-12-30 2018-08-28 Bio-Rad Laboratories, Inc. Detection and signal processing system for particle assays
JP6286455B2 (ja) * 2016-01-20 2018-02-28 シスメックス株式会社 細胞分析方法、癌化情報提供方法、細胞分析装置および癌化情報提供装置
KR101766838B1 (ko) * 2016-01-26 2017-08-23 윈포시스(주) 입자 분석 장치
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CN107645625B (zh) * 2016-07-22 2020-10-09 松下知识产权经营株式会社 图像生成装置以及图像生成方法
DE102016013236B4 (de) * 2016-11-07 2020-07-16 Particle Metrix Gmbh Vorrichtung und Verfahren zum Messen der Konzentration, der Größe und des Zetapotentials von Nanopartikeln in Flüssigkeiten im Streulichtmodus und im Fluoreszenzmodus
US10088660B2 (en) 2017-02-10 2018-10-02 Amgen Inc. Imaging system for counting and sizing particles in fluid-filled vessels
JP7058271B2 (ja) * 2017-07-26 2022-04-21 浜松ホトニクス株式会社 試料観察装置及び試料観察方法
JP7326256B2 (ja) 2017-10-26 2023-08-15 パーティクル・メージャーリング・システムズ・インコーポレーテッド 粒子計測システム及び方法
KR102333898B1 (ko) * 2019-04-09 2021-12-01 가부시끼가이샤 히다치 세이사꾸쇼 입자 사이즈 측정 장치 및 측정 방법
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Also Published As

Publication number Publication date
US8772738B2 (en) 2014-07-08
EP2327977A2 (en) 2011-06-01
CN102156088B (zh) 2014-03-12
EP2327977A3 (en) 2017-08-23
JP2011133460A (ja) 2011-07-07
CN102156088A (zh) 2011-08-17
US20110127444A1 (en) 2011-06-02

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