JP5355856B2 - Ｖｅｇｆアンタゴニストおよび抗増殖性薬剤の組成物ならびに癌の処置のためのその使用 - Google Patents

Ｖｅｇｆアンタゴニストおよび抗増殖性薬剤の組成物ならびに癌の処置のためのその使用 Download PDF

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JP5355856B2
JP5355856B2 JP2006521281A JP2006521281A JP5355856B2 JP 5355856 B2 JP5355856 B2 JP 5355856B2 JP 2006521281 A JP2006521281 A JP 2006521281A JP 2006521281 A JP2006521281 A JP 2006521281A JP 5355856 B2 JP5355856 B2 JP 5355856B2
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vegf trap
paclitaxel
vegf
agent
seq
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JP2007500131A5 (https=
JP2007500131A (ja
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ジョセリン ホラッシュ，
ロバート ジャフェ，
リミン フー，
ジョージ ディー． ヤンコプロス，
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Regeneron Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006521281A 2003-07-25 2004-07-23 Ｖｅｇｆアンタゴニストおよび抗増殖性薬剤の組成物ならびに癌の処置のためのその使用 Expired - Lifetime JP5355856B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49000203P 2003-07-25 2003-07-25
US60/490,002 2003-07-25
US49397103P 2003-08-08 2003-08-08
US60/493,971 2003-08-08
PCT/US2004/023815 WO2005011734A2 (en) 2003-07-25 2004-07-23 Composition of a vegf antagonist and an anti-proliferative agent and its use for the treatment of cancer

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JP2007500131A JP2007500131A (ja) 2007-01-11
JP2007500131A5 JP2007500131A5 (https=) 2010-12-24
JP5355856B2 true JP5355856B2 (ja) 2013-11-27

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JP2006521281A Expired - Lifetime JP5355856B2 (ja) 2003-07-25 2004-07-23 Ｖｅｇｆアンタゴニストおよび抗増殖性薬剤の組成物ならびに癌の処置のためのその使用

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US (1) US7354579B2 (https=)
EP (1) EP1648428A2 (https=)
JP (1) JP5355856B2 (https=)
KR (1) KR101175990B1 (https=)
AR (1) AR046510A1 (https=)
AU (1) AU2004261165C1 (https=)
BR (1) BRPI0412798A (https=)
CA (1) CA2529742C (https=)
IL (1) IL172406A (https=)
MX (1) MXPA05013642A (https=)
MY (1) MY149169A (https=)
NO (1) NO20060924L (https=)
NZ (1) NZ544570A (https=)
RU (1) RU2353353C2 (https=)
TW (1) TWI351953B (https=)
UY (1) UY28438A1 (https=)
WO (1) WO2005011734A2 (https=)

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AR046510A1 (es) 2005-12-14
US20050032699A1 (en) 2005-02-10
RU2006105496A (ru) 2006-06-10
MY149169A (en) 2013-07-31
US7354579B2 (en) 2008-04-08
KR101175990B1 (ko) 2012-08-23
TW200524589A (en) 2005-08-01
KR20060028654A (ko) 2006-03-30
CA2529742A1 (en) 2005-02-10
AU2004261165B2 (en) 2009-07-16
AU2004261165C1 (en) 2009-12-17
TWI351953B (en) 2011-11-11
BRPI0412798A (pt) 2006-09-26
AU2004261165A1 (en) 2005-02-10
IL172406A (en) 2016-04-21
NO20060924L (no) 2006-04-25
EP1648428A2 (en) 2006-04-26
CA2529742C (en) 2012-09-18
MXPA05013642A (es) 2006-03-10
WO2005011734A2 (en) 2005-02-10
IL172406A0 (en) 2006-04-10
RU2353353C2 (ru) 2009-04-27
JP2007500131A (ja) 2007-01-11
UY28438A1 (es) 2004-11-08
WO2005011734A3 (en) 2005-04-14
NZ544570A (en) 2008-08-29

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