KR101175990B1 - Ｖｅｇｆ 길항제와 항증식성 제제의 조성물 - Google Patents
Ｖｅｇｆ 길항제와 항증식성 제제의 조성물 Download PDFInfo
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- KR101175990B1 KR101175990B1 KR1020067000521A KR20067000521A KR101175990B1 KR 101175990 B1 KR101175990 B1 KR 101175990B1 KR 1020067000521 A KR1020067000521 A KR 1020067000521A KR 20067000521 A KR20067000521 A KR 20067000521A KR 101175990 B1 KR101175990 B1 KR 101175990B1
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Bioinformatics & Cheminformatics (AREA)
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- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49000203P | 2003-07-25 | 2003-07-25 | |
| US60/490,002 | 2003-07-25 | ||
| US49397103P | 2003-08-08 | 2003-08-08 | |
| US60/493,971 | 2003-08-08 | ||
| PCT/US2004/023815 WO2005011734A2 (en) | 2003-07-25 | 2004-07-23 | Composition of a vegf antagonist and an anti-proliferative agent and its use for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20060028654A KR20060028654A (ko) | 2006-03-30 |
| KR101175990B1 true KR101175990B1 (ko) | 2012-08-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020067000521A Expired - Lifetime KR101175990B1 (ko) | 2003-07-25 | 2004-07-23 | Ｖｅｇｆ 길항제와 항증식성 제제의 조성물 |
Country Status (17)
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| US (1) | US7354579B2 (https=) |
| EP (1) | EP1648428A2 (https=) |
| JP (1) | JP5355856B2 (https=) |
| KR (1) | KR101175990B1 (https=) |
| AR (1) | AR046510A1 (https=) |
| AU (1) | AU2004261165C1 (https=) |
| BR (1) | BRPI0412798A (https=) |
| CA (1) | CA2529742C (https=) |
| IL (1) | IL172406A (https=) |
| MX (1) | MXPA05013642A (https=) |
| MY (1) | MY149169A (https=) |
| NO (1) | NO20060924L (https=) |
| NZ (1) | NZ544570A (https=) |
| RU (1) | RU2353353C2 (https=) |
| TW (1) | TWI351953B (https=) |
| UY (1) | UY28438A1 (https=) |
| WO (1) | WO2005011734A2 (https=) |
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| AU2003244817B2 (en) * | 2002-06-28 | 2010-08-26 | Domantis Limited | Antigen-binding immunoglobulin single variable domains and dual-specific constructs |
| US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| US7696320B2 (en) | 2004-08-24 | 2010-04-13 | Domantis Limited | Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor |
| EP1578801A2 (en) * | 2002-12-27 | 2005-09-28 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| WO2004110490A2 (en) * | 2003-06-06 | 2004-12-23 | Regeneron Pharmaceuticals, Inc. | Use of vegf inhibitors for tumor regression |
| FR2878749B1 (fr) * | 2004-12-03 | 2007-12-21 | Aventis Pharma Sa | Combinaisons antitumorales contenant en agent inhibiteur de vegt et du 5fu ou un de ses derives |
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| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
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| KR20070114753A (ko) * | 2005-02-18 | 2007-12-04 | 아브락시스 바이오사이언스 인크. | 치료제의 조합 및 투여 방식, 및 조합 요법 |
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| RU2494108C2 (ru) | 2006-04-07 | 2013-09-27 | Аерпио Терапетикс, Инк. | Антитела, которые связывают человеческий белок бета-тирозин фосфатазу (нртрвета), и их использование |
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| KR20240008821A (ko) | 2021-05-17 | 2024-01-19 | 리제너론 파아마슈티컬스, 인크. | 혈관신생성 눈 장애 치료를 위한 연장된 고용량 vegf 길항제 요법 |
| IL315347A (en) | 2022-03-15 | 2024-11-01 | Regeneron Pharma | Prolonged high-dose VEGF antagonist regimens for the treatment of angiogenic ocular disorders |
| IL315374A (en) | 2022-03-15 | 2024-11-01 | Regeneron Pharma | Prolonged high-dose VEGF antagonist regimens for the treatment of angiogenic ocular disorders |
| CN121712520A (zh) | 2023-06-23 | 2026-03-20 | 瑞泽恩制药公司 | 用于治疗血管生成性眼病的延长的高剂量vegf拮抗剂方案 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000075319A1 (en) * | 1999-06-08 | 2000-12-14 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
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| US6811779B2 (en) * | 1994-02-10 | 2004-11-02 | Imclone Systems Incorporated | Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy |
| US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| US6342219B1 (en) * | 1999-04-28 | 2002-01-29 | Board Of Regents, The University Of Texas System | Antibody compositions for selectively inhibiting VEGF |
| WO2004110490A2 (en) * | 2003-06-06 | 2004-12-23 | Regeneron Pharmaceuticals, Inc. | Use of vegf inhibitors for tumor regression |
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- 2004-07-23 EP EP04779050A patent/EP1648428A2/en not_active Withdrawn
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2000075319A1 (en) * | 1999-06-08 | 2000-12-14 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
Also Published As
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| AR046510A1 (es) | 2005-12-14 |
| US20050032699A1 (en) | 2005-02-10 |
| RU2006105496A (ru) | 2006-06-10 |
| MY149169A (en) | 2013-07-31 |
| US7354579B2 (en) | 2008-04-08 |
| TW200524589A (en) | 2005-08-01 |
| KR20060028654A (ko) | 2006-03-30 |
| CA2529742A1 (en) | 2005-02-10 |
| AU2004261165B2 (en) | 2009-07-16 |
| AU2004261165C1 (en) | 2009-12-17 |
| JP5355856B2 (ja) | 2013-11-27 |
| TWI351953B (en) | 2011-11-11 |
| BRPI0412798A (pt) | 2006-09-26 |
| AU2004261165A1 (en) | 2005-02-10 |
| IL172406A (en) | 2016-04-21 |
| NO20060924L (no) | 2006-04-25 |
| EP1648428A2 (en) | 2006-04-26 |
| CA2529742C (en) | 2012-09-18 |
| MXPA05013642A (es) | 2006-03-10 |
| WO2005011734A2 (en) | 2005-02-10 |
| IL172406A0 (en) | 2006-04-10 |
| RU2353353C2 (ru) | 2009-04-27 |
| JP2007500131A (ja) | 2007-01-11 |
| UY28438A1 (es) | 2004-11-08 |
| WO2005011734A3 (en) | 2005-04-14 |
| NZ544570A (en) | 2008-08-29 |
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