JP5270167B2 - （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 - Google Patents

（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 Download PDF

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JP5270167B2
JP5270167B2 JP2007547060A JP2007547060A JP5270167B2 JP 5270167 B2 JP5270167 B2 JP 5270167B2 JP 2007547060 A JP2007547060 A JP 2007547060A JP 2007547060 A JP2007547060 A JP 2007547060A JP 5270167 B2 JP5270167 B2 JP 5270167B2
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hemihydrate
disorder
composition
compound according
tetrahydro
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JP2008524262A5 (OSRAM
JP2008524262A (ja
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ラジェッシュ クマール アガーワル，
ウィリアム エル． ザ サード ベッツ，
ジェームス エー． ヘンシルウッド，
ユアン−ホン キヤン，
ノア ポスト，
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アリーナ ファーマシューティカルズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A61P25/32—Alcohol-abuse
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP2007547060A 2004-12-21 2005-12-20 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 Expired - Lifetime JP5270167B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63822104P 2004-12-21 2004-12-21
US60/638,221 2004-12-21
PCT/US2005/046983 WO2006069363A2 (en) 2004-12-21 2005-12-20 Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride

Related Child Applications (1)

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JP2012114460A Division JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

Publications (3)

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JP2008524262A JP2008524262A (ja) 2008-07-10
JP2008524262A5 JP2008524262A5 (OSRAM) 2009-02-05
JP5270167B2 true JP5270167B2 (ja) 2013-08-21

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JP2007547060A Expired - Lifetime JP5270167B2 (ja) 2004-12-21 2005-12-20 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2012114460A Expired - Lifetime JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2014113743A Pending JP2014156490A (ja) 2004-12-21 2014-06-02 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

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JP2012114460A Expired - Lifetime JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2014113743A Pending JP2014156490A (ja) 2004-12-21 2014-06-02 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

Country Status (28)

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US (4) US8168624B2 (OSRAM)
EP (3) EP2327698B1 (OSRAM)
JP (3) JP5270167B2 (OSRAM)
KR (1) KR101281919B1 (OSRAM)
CN (2) CN102321023A (OSRAM)
AT (1) ATE442359T1 (OSRAM)
AU (1) AU2005318959B2 (OSRAM)
BR (1) BRPI0519726B8 (OSRAM)
CA (1) CA2589988C (OSRAM)
CU (1) CU20070138A7 (OSRAM)
CY (1) CY1109599T1 (OSRAM)
DE (1) DE602005016603D1 (OSRAM)
DK (1) DK1838677T3 (OSRAM)
EA (2) EA201200954A1 (OSRAM)
ES (1) ES2332009T3 (OSRAM)
HR (1) HRP20090640T1 (OSRAM)
IL (1) IL183844A (OSRAM)
MA (1) MA29147B1 (OSRAM)
ME (1) ME01090B (OSRAM)
NI (1) NI200700160A (OSRAM)
NZ (2) NZ555981A (OSRAM)
PL (1) PL1838677T3 (OSRAM)
PT (1) PT1838677E (OSRAM)
RS (1) RS50996B (OSRAM)
SI (1) SI1838677T1 (OSRAM)
TN (1) TNSN07235A1 (OSRAM)
WO (1) WO2006069363A2 (OSRAM)
ZA (1) ZA200705125B (OSRAM)

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