JP5135504B2 - 非天然アミノ酸のインビボ組込み用直交翻訳成分 - Google Patents

非天然アミノ酸のインビボ組込み用直交翻訳成分 Download PDF

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JP5135504B2
JP5135504B2 JP2007539228A JP2007539228A JP5135504B2 JP 5135504 B2 JP5135504 B2 JP 5135504B2 JP 2007539228 A JP2007539228 A JP 2007539228A JP 2007539228 A JP2007539228 A JP 2007539228A JP 5135504 B2 JP5135504 B2 JP 5135504B2
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trna
amino acid
unnatural amino
protein
synthetase
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JP2008517631A5 (enExample
JP2008517631A (ja
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ピーター・シュルツ
リタル・アルフォンタ
ジョナサン・アール.・チッツルル
アレキサンダー・ディーターズ
ダン・グロフ
ダニエル・サマラー
メン−リン・ツァオ
チャンユウ・ワン
ニング・ウー
ジアンミング・ズィー
ホァチャン・ツェン
モハマッド・アール.・セイヤエデサヤムドスト
ジェームス・ターナー
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ザ スクリプス リサーチ インスティチュート
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1058Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2007539228A 2004-10-27 2005-10-27 非天然アミノ酸のインビボ組込み用直交翻訳成分 Expired - Fee Related JP5135504B2 (ja)

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US62273804P 2004-10-27 2004-10-27
US60/622,738 2004-10-27
PCT/US2005/039210 WO2006110182A2 (en) 2004-10-27 2005-10-27 Orthogonal translation components for the in vivo incorporation of unnatural amino acids

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JP2008517631A JP2008517631A (ja) 2008-05-29
JP2008517631A5 JP2008517631A5 (enExample) 2008-12-04
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JP2011255180A Expired - Fee Related JP5539948B2 (ja) 2004-10-27 2011-11-22 非天然アミノ酸のインビボ組込み用直交翻訳成分

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US (2) US8216804B2 (enExample)
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CN (2) CN102827827B (enExample)
AU (1) AU2005330514B2 (enExample)
BR (1) BRPI0517381A (enExample)
CA (1) CA2583735A1 (enExample)
IL (2) IL182495A0 (enExample)
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BRPI0517381A (pt) 2008-10-07
MX2007004892A (es) 2007-08-16
EP2383340A3 (en) 2012-03-21
US20130244245A1 (en) 2013-09-19
JP5539948B2 (ja) 2014-07-02
WO2006110182A3 (en) 2006-12-21
CN101048506A (zh) 2007-10-03
EP2380982A1 (en) 2011-10-26
CN101048506B (zh) 2013-06-26
CN102827827A (zh) 2012-12-19
WO2006110182A2 (en) 2006-10-19
JP2012254073A (ja) 2012-12-27
IL211229A0 (en) 2011-04-28
AU2005330514B2 (en) 2011-05-12
US8216804B2 (en) 2012-07-10
EP2380982B1 (en) 2014-07-16
EP1807515A2 (en) 2007-07-18
CA2583735A1 (en) 2006-10-19
EP1807515A4 (en) 2008-06-18
JP2008517631A (ja) 2008-05-29
IL182495A0 (en) 2007-09-20
EP2383340A2 (en) 2011-11-02
CN102827827B (zh) 2014-10-29
AU2005330514A1 (en) 2006-10-19
US9102932B2 (en) 2015-08-11
EP2383340B1 (en) 2014-07-16
US20080233611A1 (en) 2008-09-25

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