IL182495A0 - Orthogonal translation components for the in vivo incorporation of unnatural amino acids - Google Patents

Orthogonal translation components for the in vivo incorporation of unnatural amino acids

Info

Publication number
IL182495A0
IL182495A0 IL182495A IL18249507A IL182495A0 IL 182495 A0 IL182495 A0 IL 182495A0 IL 182495 A IL182495 A IL 182495A IL 18249507 A IL18249507 A IL 18249507A IL 182495 A0 IL182495 A0 IL 182495A0
Authority
IL
Israel
Prior art keywords
amino acids
unnatural amino
vivo incorporation
translation components
orthogonal translation
Prior art date
Application number
IL182495A
Other languages
English (en)
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of IL182495A0 publication Critical patent/IL182495A0/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Ecology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IL182495A 2004-10-27 2007-04-12 Orthogonal translation components for the in vivo incorporation of unnatural amino acids IL182495A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62273804P 2004-10-27 2004-10-27
PCT/US2005/039210 WO2006110182A2 (en) 2004-10-27 2005-10-27 Orthogonal translation components for the in vivo incorporation of unnatural amino acids

Publications (1)

Publication Number Publication Date
IL182495A0 true IL182495A0 (en) 2007-09-20

Family

ID=37087466

Family Applications (2)

Application Number Title Priority Date Filing Date
IL182495A IL182495A0 (en) 2004-10-27 2007-04-12 Orthogonal translation components for the in vivo incorporation of unnatural amino acids
IL211229A IL211229A0 (en) 2004-10-27 2011-02-15 Translation system for producing a protein comprising an unnatural amino acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL211229A IL211229A0 (en) 2004-10-27 2011-02-15 Translation system for producing a protein comprising an unnatural amino acid

Country Status (10)

Country Link
US (2) US8216804B2 (enExample)
EP (3) EP2380982B1 (enExample)
JP (2) JP5135504B2 (enExample)
CN (2) CN102827827B (enExample)
AU (1) AU2005330514B2 (enExample)
BR (1) BRPI0517381A (enExample)
CA (1) CA2583735A1 (enExample)
IL (2) IL182495A0 (enExample)
MX (1) MX2007004892A (enExample)
WO (1) WO2006110182A2 (enExample)

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Also Published As

Publication number Publication date
IL211229A0 (en) 2011-04-28
EP2383340B1 (en) 2014-07-16
MX2007004892A (es) 2007-08-16
US20080233611A1 (en) 2008-09-25
EP1807515A4 (en) 2008-06-18
CN102827827B (zh) 2014-10-29
EP2383340A2 (en) 2011-11-02
AU2005330514A1 (en) 2006-10-19
CN101048506B (zh) 2013-06-26
WO2006110182A3 (en) 2006-12-21
EP1807515A2 (en) 2007-07-18
JP2008517631A (ja) 2008-05-29
JP5135504B2 (ja) 2013-02-06
JP5539948B2 (ja) 2014-07-02
JP2012254073A (ja) 2012-12-27
EP2380982B1 (en) 2014-07-16
CN101048506A (zh) 2007-10-03
BRPI0517381A (pt) 2008-10-07
CN102827827A (zh) 2012-12-19
US20130244245A1 (en) 2013-09-19
EP2380982A1 (en) 2011-10-26
US8216804B2 (en) 2012-07-10
EP2383340A3 (en) 2012-03-21
CA2583735A1 (en) 2006-10-19
US9102932B2 (en) 2015-08-11
WO2006110182A2 (en) 2006-10-19
AU2005330514B2 (en) 2011-05-12

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