JP5122445B2 - 抗認知症薬物の経皮吸収製剤 - Google Patents

抗認知症薬物の経皮吸収製剤 Download PDF

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JP5122445B2
JP5122445B2 JP2008514366A JP2008514366A JP5122445B2 JP 5122445 B2 JP5122445 B2 JP 5122445B2 JP 2008514366 A JP2008514366 A JP 2008514366A JP 2008514366 A JP2008514366 A JP 2008514366A JP 5122445 B2 JP5122445 B2 JP 5122445B2
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drug
meth
acrylate
ester
containing layer
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JPWO2007129427A1 (ja
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東 健 伊
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Teikoku Seiyaku Co Ltd
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Teikoku Seiyaku Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008514366A 2006-05-08 2006-12-25 抗認知症薬物の経皮吸収製剤 Active JP5122445B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79829606P 2006-05-08 2006-05-08
US60/798,296 2006-05-08
PCT/JP2006/325813 WO2007129427A1 (ja) 2006-05-08 2006-12-25 抗認知症薬物の経皮吸収製剤

Publications (2)

Publication Number Publication Date
JPWO2007129427A1 JPWO2007129427A1 (ja) 2009-09-17
JP5122445B2 true JP5122445B2 (ja) 2013-01-16

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JP2008514366A Active JP5122445B2 (ja) 2006-05-08 2006-12-25 抗認知症薬物の経皮吸収製剤

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US (2) US7858114B2 (https=)
EP (1) EP2016939B1 (https=)
JP (1) JP5122445B2 (https=)
KR (1) KR20090009951A (https=)
CN (1) CN101460156B (https=)
AU (1) AU2006343077B2 (https=)
BR (1) BRPI0621655A2 (https=)
CA (1) CA2651596C (https=)
ES (1) ES2466647T3 (https=)
IL (1) IL195174A0 (https=)
IN (1) IN266817B (https=)
MY (1) MY149152A (https=)
NO (1) NO20084614L (https=)
NZ (1) NZ572809A (https=)
RU (1) RU2428179C2 (https=)
WO (1) WO2007129427A1 (https=)

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US20100048628A1 (en) * 2006-12-01 2010-02-25 Sumiyo Nishi Method for suppressing discoloration over time of adhesive preparation containing donepezil
JP5237112B2 (ja) * 2006-12-01 2013-07-17 日東電工株式会社 経皮吸収製剤
EP2269653A4 (en) * 2008-03-25 2013-10-23 Teikoku Seiyaku Kk COMPOSITION FOR THE STABILIZATION OF BLOCKER AND THE COMPOSITION COMPRISING TRANSDERMAL ABSORBABLE PREPARATION
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
WO2009145177A1 (ja) * 2008-05-30 2009-12-03 日東電工株式会社 ドネペジル含有貼付製剤およびその包装体
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CA2733265A1 (en) * 2008-09-30 2010-04-08 Teikoku Pharma Usa, Inc. Transdermal extended-delivery donepezil compositions and methods for using the same
US20100278895A1 (en) 2009-04-30 2010-11-04 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
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EP2514414A4 (en) * 2009-12-16 2013-05-29 Goto Takeshi TRANSDERMAL ABSORBED PREPARATION OF ANTI-DENSITY ACTIVE SUBSTANCE
CN102834092A (zh) * 2009-12-16 2012-12-19 后藤武 抗痴呆药物的经皮吸收制剂
JP2012236773A (ja) * 2009-12-16 2012-12-06 Goto Takeshi 抗認知症薬物の経皮吸収製剤
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US10076502B2 (en) 2009-12-22 2018-09-18 Luye Pharma Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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KR101317158B1 (ko) * 2011-02-18 2013-10-15 조선대학교산학협력단 갈란타민 또는 그의 염을 함유하는 경피흡수제제
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KR101395557B1 (ko) * 2011-08-25 2014-05-16 아이큐어 주식회사 경피 흡수 제제 및 그 제조방법
KR101239150B1 (ko) 2012-02-28 2013-03-06 에스케이케미칼주식회사 도네페질-함유 경피흡수제제 및 그의 제조방법
KR101964295B1 (ko) * 2012-09-05 2019-04-01 주식회사 한독 피부 자극이 감소된 메만틴 경피전달 시스템
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JP6151935B2 (ja) * 2013-03-11 2017-06-21 日東電工株式会社 経皮吸収促進用組成物および貼付製剤
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CN108135860A (zh) 2015-06-22 2018-06-08 考里安国际公司 包含难溶性治疗剂的透皮粘合剂组合物
WO2017002865A1 (ja) 2015-06-29 2017-01-05 積水化学工業株式会社 コアシェル構造体及び外用剤
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JPH04117323A (ja) * 1990-09-04 1992-04-17 Sekisui Chem Co Ltd 経皮吸収貼付剤
JPH05500511A (ja) * 1989-09-14 1993-02-04 シグナス，インコーポレイテッド 送達開始を遅延させた経皮送達装置
JPH06199659A (ja) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
JPH06510043A (ja) * 1991-08-23 1994-11-10 シグナス，インコーポレイテッド 薬効遅延を達成するために膜で保護された微細孔膜を用いる経皮ドラッグデリバリーデバイス
JPH10182439A (ja) * 1996-12-20 1998-07-07 Roehm Gmbh 皮膚もしくは経皮の治療系のための付着−及び接合剤
JPH11501527A (ja) * 1994-09-29 1999-02-09 アルザ・コーポレーション 離層の少ない改良された経皮デバイス
JPH11315016A (ja) * 1998-03-03 1999-11-16 Eisai Co Ltd 抗痴呆薬を含有した経皮適用製剤又は坐剤
WO2002038139A1 (en) * 2000-11-07 2002-05-16 Hisamitsu Pharmaceutical Co., Inc. Pharmaceutical preparation of percutaneous absorption type
JP2003505411A (ja) * 1999-07-22 2003-02-12 エルテーエス ローマン テラピー−ジステーメ アーゲー カルシウムアンタゴニストを投与するための経皮治療系
WO2003032960A1 (en) * 2001-10-17 2003-04-24 Hisamitsu Pharmaceutical Co., Inc. Percutaneous absorption preparations
WO2003092677A1 (de) * 2002-05-06 2003-11-13 Schwarz Pharma Ag Transepikutane darreichungsform zur behandlung des restless leg syndroms
JP2004502725A (ja) * 2000-07-12 2004-01-29 ヘクサル・アクチェンゲゼルシャフト 高分散シリカを用いた経皮治療システム
JP2004509916A (ja) * 2000-09-26 2004-04-02 ピエール、ファーブル、メディカマン オキサンに基づく薬剤
JP2004514738A (ja) * 2000-12-06 2004-05-20 エルテーエス　ローマン　テラピー−ジステーメ　アーゲー 活性物質としてオキシブチニンで構成される経皮治療システム
JP2005194230A (ja) * 2004-01-07 2005-07-21 Hisamitsu Pharmaceut Co Inc 異型断面繊維を使用した支持体を有するテーピング型貼付剤
WO2005115355A1 (ja) * 2004-05-28 2005-12-08 Hisamitsu Pharmaceutical Co., Inc. 貼付製剤

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JPH05500511A (ja) * 1989-09-14 1993-02-04 シグナス，インコーポレイテッド 送達開始を遅延させた経皮送達装置
JPH04117323A (ja) * 1990-09-04 1992-04-17 Sekisui Chem Co Ltd 経皮吸収貼付剤
JPH06510043A (ja) * 1991-08-23 1994-11-10 シグナス，インコーポレイテッド 薬効遅延を達成するために膜で保護された微細孔膜を用いる経皮ドラッグデリバリーデバイス
JPH06199659A (ja) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
JPH11501527A (ja) * 1994-09-29 1999-02-09 アルザ・コーポレーション 離層の少ない改良された経皮デバイス
JPH10182439A (ja) * 1996-12-20 1998-07-07 Roehm Gmbh 皮膚もしくは経皮の治療系のための付着−及び接合剤
JPH11315016A (ja) * 1998-03-03 1999-11-16 Eisai Co Ltd 抗痴呆薬を含有した経皮適用製剤又は坐剤
JP2003505411A (ja) * 1999-07-22 2003-02-12 エルテーエス ローマン テラピー−ジステーメ アーゲー カルシウムアンタゴニストを投与するための経皮治療系
JP2004502725A (ja) * 2000-07-12 2004-01-29 ヘクサル・アクチェンゲゼルシャフト 高分散シリカを用いた経皮治療システム
JP2004509916A (ja) * 2000-09-26 2004-04-02 ピエール、ファーブル、メディカマン オキサンに基づく薬剤
WO2002038139A1 (en) * 2000-11-07 2002-05-16 Hisamitsu Pharmaceutical Co., Inc. Pharmaceutical preparation of percutaneous absorption type
JP2004514738A (ja) * 2000-12-06 2004-05-20 エルテーエス　ローマン　テラピー−ジステーメ　アーゲー 活性物質としてオキシブチニンで構成される経皮治療システム
WO2003032960A1 (en) * 2001-10-17 2003-04-24 Hisamitsu Pharmaceutical Co., Inc. Percutaneous absorption preparations
WO2003092677A1 (de) * 2002-05-06 2003-11-13 Schwarz Pharma Ag Transepikutane darreichungsform zur behandlung des restless leg syndroms
JP2005194230A (ja) * 2004-01-07 2005-07-21 Hisamitsu Pharmaceut Co Inc 異型断面繊維を使用した支持体を有するテーピング型貼付剤
WO2005115355A1 (ja) * 2004-05-28 2005-12-08 Hisamitsu Pharmaceutical Co., Inc. 貼付製剤

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Publication number Publication date
IL195174A0 (en) 2009-08-03
US20110059141A1 (en) 2011-03-10
US7858114B2 (en) 2010-12-28
EP2016939A1 (en) 2009-01-21
EP2016939A4 (en) 2013-01-09
US20070259028A1 (en) 2007-11-08
CA2651596A1 (en) 2007-11-15
AU2006343077B2 (en) 2012-11-08
BRPI0621655A2 (pt) 2011-12-20
CN101460156B (zh) 2011-06-08
IN266817B (https=) 2015-06-03
MY149152A (en) 2013-07-15
RU2428179C2 (ru) 2011-09-10
KR20090009951A (ko) 2009-01-23
RU2008148131A (ru) 2010-06-20
WO2007129427A1 (ja) 2007-11-15
EP2016939B1 (en) 2014-03-19
AU2006343077A1 (en) 2007-11-15
ES2466647T3 (es) 2014-06-10
NO20084614L (no) 2009-02-06
CN101460156A (zh) 2009-06-17
CA2651596C (en) 2014-03-25
JPWO2007129427A1 (ja) 2009-09-17
HK1130175A1 (en) 2009-12-24
NZ572809A (en) 2011-02-25

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