NZ572809A - Transdermally absorbable preparation comprising anti-dementia agent - Google Patents
Transdermally absorbable preparation comprising anti-dementia agentInfo
- Publication number
- NZ572809A NZ572809A NZ572809A NZ57280906A NZ572809A NZ 572809 A NZ572809 A NZ 572809A NZ 572809 A NZ572809 A NZ 572809A NZ 57280906 A NZ57280906 A NZ 57280906A NZ 572809 A NZ572809 A NZ 572809A
- Authority
- NZ
- New Zealand
- Prior art keywords
- acrylate
- meth
- drug
- ester
- percutaneous absorption
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 84
- 239000002664 nootropic agent Substances 0.000 title claims abstract description 59
- 229940125682 antidementia agent Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 claims abstract description 108
- 229940079593 drug Drugs 0.000 claims abstract description 103
- -1 alkyl citrate ester Chemical class 0.000 claims abstract description 81
- 238000010521 absorption reaction Methods 0.000 claims abstract description 64
- 229940005524 anti-dementia drug Drugs 0.000 claims abstract description 60
- 230000001464 adherent effect Effects 0.000 claims abstract description 46
- 239000012528 membrane Substances 0.000 claims abstract description 35
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 34
- 239000000194 fatty acid Substances 0.000 claims abstract description 34
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- 229920001577 copolymer Polymers 0.000 claims abstract description 33
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 31
- 229940116351 sebacate Drugs 0.000 claims abstract description 21
- 150000003839 salts Chemical class 0.000 claims abstract description 19
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 18
- 239000011505 plaster Substances 0.000 claims abstract description 16
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- 239000011148 porous material Substances 0.000 claims abstract description 12
- 229920001567 vinyl ester resin Polymers 0.000 claims abstract description 11
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 claims abstract description 8
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- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 72
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- WEAPVABOECTMGR-UHFFFAOYSA-N triethyl 2-acetyloxypropane-1,2,3-tricarboxylate Chemical compound CCOC(=O)CC(C(=O)OCC)(OC(C)=O)CC(=O)OCC WEAPVABOECTMGR-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79829606P | 2006-05-08 | 2006-05-08 | |
| PCT/JP2006/325813 WO2007129427A1 (ja) | 2006-05-08 | 2006-12-25 | 抗認知症薬物の経皮吸収製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ572809A true NZ572809A (en) | 2011-02-25 |
Family
ID=38667540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ572809A NZ572809A (en) | 2006-05-08 | 2006-12-25 | Transdermally absorbable preparation comprising anti-dementia agent |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7858114B2 (https=) |
| EP (1) | EP2016939B1 (https=) |
| JP (1) | JP5122445B2 (https=) |
| KR (1) | KR20090009951A (https=) |
| CN (1) | CN101460156B (https=) |
| AU (1) | AU2006343077B2 (https=) |
| BR (1) | BRPI0621655A2 (https=) |
| CA (1) | CA2651596C (https=) |
| ES (1) | ES2466647T3 (https=) |
| IL (1) | IL195174A0 (https=) |
| IN (1) | IN266817B (https=) |
| MY (1) | MY149152A (https=) |
| NO (1) | NO20084614L (https=) |
| NZ (1) | NZ572809A (https=) |
| RU (1) | RU2428179C2 (https=) |
| WO (1) | WO2007129427A1 (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2452474C2 (ru) * | 2006-12-01 | 2012-06-10 | Нитто Денко Корпорейшн | Стабилизированная адгезивная композиция, содержащая донепезил |
| US20100062045A1 (en) * | 2006-12-01 | 2010-03-11 | Nitto Denko Corporation | Method for suppressing coloring of adhesive prepartion containing donepezil and method for reducing amounts of donepezil-related substances formed |
| AU2009229994B2 (en) * | 2008-03-25 | 2015-04-16 | Teikoku Seiyaku Co., Ltd. | Transdermally absorbable preparation |
| US20090291127A1 (en) * | 2008-05-21 | 2009-11-26 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| CN102046171B (zh) * | 2008-05-30 | 2013-06-19 | 日东电工株式会社 | 经皮吸收制剂 |
| RU2481826C2 (ru) * | 2008-05-30 | 2013-05-20 | Нитто Денко Корпорейшн | Содержащий донепезил адгезивный препарат и упаковка для него |
| JP2012504163A (ja) * | 2008-09-30 | 2012-02-16 | テイコク ファーマ ユーエスエー インコーポレーテッド | 経皮持続送達ドネペジル組成物および該組成物を使用する方法 |
| US8858983B2 (en) | 2009-04-30 | 2014-10-14 | Medtronic, Inc. | Antioxidants and antimicrobial accessories including antioxidants |
| KR101325104B1 (ko) | 2009-09-16 | 2013-11-07 | 주식회사 삼양바이오팜 | 경피 투여 제형 및 그 제조 방법 |
| JP2012236773A (ja) * | 2009-12-16 | 2012-12-06 | Goto Takeshi | 抗認知症薬物の経皮吸収製剤 |
| JPWO2011074637A1 (ja) * | 2009-12-16 | 2013-04-25 | 後藤 武 | 抗認知症薬物の経皮吸収製剤 |
| KR20120101704A (ko) * | 2009-12-16 | 2012-09-14 | 고토 다케시 | 항인지증 약물의 경피흡수제제 |
| US10076502B2 (en) | 2009-12-22 | 2018-09-18 | Luye Pharma Ag | Transdermal therapeutic system for administering rivastigmine or derivatives thereof |
| BR112012017168B1 (pt) * | 2009-12-22 | 2022-03-15 | Luye Pharma Ag | Sistemas terapêuticos transdérmicos, seu processo de preparação, e usos de um polímero ou copolímero |
| US20100178307A1 (en) * | 2010-01-13 | 2010-07-15 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| NZ605352A (en) | 2010-06-30 | 2013-10-25 | Nal Pharmaceuticals Ltd | Process for producing glycosaminoglycans |
| RS54173B1 (sr) * | 2010-12-14 | 2015-12-31 | Acino Ag | Transdermalni terapijski sistem za davanje aktivne supstance |
| US8911427B2 (en) | 2010-12-28 | 2014-12-16 | Medtronic, Inc. | Therapeutic agent reservoir delivery system |
| TWI433904B (zh) * | 2011-01-12 | 2014-04-11 | Taiwan Biotech Co Ltd | 多奈哌齊經皮貼片 |
| KR101054317B1 (ko) | 2011-01-28 | 2011-08-08 | 신신제약 주식회사 | 리바스티그민을 함유하는 경피흡수제제 |
| KR101317158B1 (ko) | 2011-02-18 | 2013-10-15 | 조선대학교산학협력단 | 갈란타민 또는 그의 염을 함유하는 경피흡수제제 |
| WO2012161489A2 (ko) * | 2011-05-20 | 2012-11-29 | 에스케이케미칼 주식회사 | 리바스티그민 함유 패취 |
| KR101395557B1 (ko) * | 2011-08-25 | 2014-05-16 | 아이큐어 주식회사 | 경피 흡수 제제 및 그 제조방법 |
| KR101239150B1 (ko) | 2012-02-28 | 2013-03-06 | 에스케이케미칼주식회사 | 도네페질-함유 경피흡수제제 및 그의 제조방법 |
| KR101964295B1 (ko) * | 2012-09-05 | 2019-04-01 | 주식회사 한독 | 피부 자극이 감소된 메만틴 경피전달 시스템 |
| PL2931276T3 (pl) * | 2012-12-13 | 2018-06-29 | H. Lundbeck A/S | Kompozycje zawierające wortioksetynę i donepezil |
| JP6151935B2 (ja) * | 2013-03-11 | 2017-06-21 | 日東電工株式会社 | 経皮吸収促進用組成物および貼付製剤 |
| KR20160120778A (ko) | 2014-02-20 | 2016-10-18 | 날 파마슈티칼 그룹 리미티드 | 도네페질을 함유하는 경피흡수제제 |
| WO2016209982A1 (en) | 2015-06-22 | 2016-12-29 | Corium International, Inc. | Transdermal adhesive composition comprising a poorly soluble therapeutic agent |
| US10561603B2 (en) | 2015-06-29 | 2020-02-18 | Sekisui Chemical Co., Ltd. | Core-shell structure and topical agent |
| US10966936B2 (en) | 2015-12-30 | 2021-04-06 | Corium, Inc. | Systems comprising a composite backing and methods for long term transdermal administration |
| WO2017223402A1 (en) | 2016-06-23 | 2017-12-28 | Corium International, Inc. | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
| EP3490544A1 (en) * | 2016-07-27 | 2019-06-05 | Corium International, Inc. | Memantine transdermal delivery systems |
| WO2018022814A1 (en) * | 2016-07-27 | 2018-02-01 | Corium International, Inc. | Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery |
| CN116270551A (zh) | 2016-07-27 | 2023-06-23 | 考里安有限责任公司 | 通过盐至中性药物原位转化的组合物、透皮贴剂及应用 |
| KR102769558B1 (ko) * | 2017-02-28 | 2025-02-19 | 킴벌리-클라크 월드와이드, 인크. | 미생물총의 건강한 균형을 유지하기 위한 상승적 조성물 |
| CN108096690B (zh) * | 2017-04-07 | 2019-08-20 | 杭州多泰科技有限公司 | 一种诱导循环肿瘤细胞转移的可移植支架的制备方法 |
| KR102033686B1 (ko) | 2017-05-19 | 2019-10-18 | 보령제약 주식회사 | 도네페질을 함유하는 마이크로니들 경피 패치 |
| US20190029971A1 (en) * | 2017-07-26 | 2019-01-31 | Corium International, Inc. | Transdermal delivery system with a microporous membrane having solvent-filled pores |
| CA3085342A1 (en) | 2017-12-13 | 2019-06-20 | Corium, Inc. | Method for depot creation during transdermal drug delivery |
| US11173132B2 (en) | 2017-12-20 | 2021-11-16 | Corium, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
| CN108926549A (zh) * | 2018-09-27 | 2018-12-04 | 安徽安科余良卿药业有限公司 | 卡巴拉汀凝胶贴膏及其制备方法 |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| CA3216359A1 (en) | 2021-04-07 | 2022-10-13 | Battelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| KR102489860B1 (ko) * | 2021-09-02 | 2023-01-19 | 동아에스티 주식회사 | 메만틴 에난트산염을 포함하는 치매 치료용 경피흡수 제제 |
| CN115957200A (zh) * | 2023-02-23 | 2023-04-14 | 广州新济药业科技有限公司 | 一种美金刚透皮贴剂及制备方法 |
| AU2024353375A1 (en) | 2023-09-29 | 2026-04-09 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2065403C (en) * | 1989-09-14 | 1996-06-18 | Gary W. Cleary | Transdermal delivery device having delayed onset |
| JP2977254B2 (ja) | 1990-09-04 | 1999-11-15 | 積水化学工業株式会社 | 経皮吸収貼付剤 |
| US5273756A (en) * | 1991-08-23 | 1993-12-28 | Cygnus Therapeutic Systems | Transdermal drug delivery device using a membrane-protected microporous membrane to achieve delayed onset |
| JPH06199659A (ja) * | 1992-10-28 | 1994-07-19 | Hisamitsu Pharmaceut Co Inc | 経皮治療用装置 |
| US5919478A (en) * | 1993-06-25 | 1999-07-06 | Alza Corporation | Incorporating poly-N-vinyl amide in a transdermal system |
| FR2717689B1 (fr) * | 1994-03-28 | 1996-07-05 | Lhd Lab Hygiene Dietetique | Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base de copolymère styrène-isoprène-styrène. |
| US5635203A (en) | 1994-09-29 | 1997-06-03 | Alza Corporation | Transdermal device having decreased delamination |
| DE19533772C1 (de) * | 1995-09-12 | 1998-01-02 | Hexal Ag | Tacrin/Selegilin-Pflaster |
| DE19653605C2 (de) | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
| JPH10315016A (ja) | 1997-05-15 | 1998-12-02 | Nissan Diesel Motor Co Ltd | チャック装置 |
| JP3987655B2 (ja) * | 1998-03-03 | 2007-10-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗痴呆薬を含有した経皮適用製剤又は坐剤 |
| DE19918106A1 (de) * | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
| GB9917290D0 (en) * | 1999-07-22 | 1999-09-22 | Glaxo Wellcome Spa | Pharmaceutical composition |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| FR2814368B1 (fr) | 2000-09-26 | 2004-05-07 | Pf Medicament | Preparation pharmaceutique a base d'oxans |
| JP4057418B2 (ja) | 2000-11-07 | 2008-03-05 | 久光製薬株式会社 | 経皮吸収型製剤 |
| DE10060550C1 (de) * | 2000-12-06 | 2002-04-18 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Oxybutynin und Verfahren zur Herstellung Oxybutynin enthaltender Wirkstoffschichten |
| WO2003032960A1 (en) * | 2001-10-17 | 2003-04-24 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneous absorption preparations |
| DE10220230A1 (de) * | 2002-05-06 | 2003-11-27 | Sanol Arznei Schwarz Gmbh | Verwendung von Rotigotine zur Behandlung des Restless Leg Syndroms |
| JP4274951B2 (ja) * | 2004-01-07 | 2009-06-10 | 久光製薬株式会社 | 異型断面繊維を使用した支持体を有するテーピング型貼付剤 |
| US20080038328A1 (en) * | 2004-05-28 | 2008-02-14 | Naruhito Higo | Pasting Preparation |
-
2006
- 2006-12-25 MY MYPI20084469A patent/MY149152A/en unknown
- 2006-12-25 CN CN200680054495XA patent/CN101460156B/zh active Active
- 2006-12-25 AU AU2006343077A patent/AU2006343077B2/en active Active
- 2006-12-25 IN IN2543MUN2008 patent/IN266817B/en unknown
- 2006-12-25 RU RU2008148131/15A patent/RU2428179C2/ru not_active IP Right Cessation
- 2006-12-25 CA CA2651596A patent/CA2651596C/en active Active
- 2006-12-25 JP JP2008514366A patent/JP5122445B2/ja active Active
- 2006-12-25 NZ NZ572809A patent/NZ572809A/en not_active IP Right Cessation
- 2006-12-25 KR KR1020087029711A patent/KR20090009951A/ko not_active Ceased
- 2006-12-25 ES ES06835183.2T patent/ES2466647T3/es active Active
- 2006-12-25 EP EP06835183.2A patent/EP2016939B1/en active Active
- 2006-12-25 BR BRPI0621655-2A patent/BRPI0621655A2/pt not_active IP Right Cessation
- 2006-12-25 WO PCT/JP2006/325813 patent/WO2007129427A1/ja not_active Ceased
-
2007
- 2007-05-07 US US11/797,722 patent/US7858114B2/en not_active Expired - Fee Related
-
2008
- 2008-10-31 NO NO20084614A patent/NO20084614L/no not_active Application Discontinuation
- 2008-11-09 IL IL195174A patent/IL195174A0/en unknown
-
2010
- 2010-11-17 US US12/948,252 patent/US20110059141A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008148131A (ru) | 2010-06-20 |
| US20110059141A1 (en) | 2011-03-10 |
| RU2428179C2 (ru) | 2011-09-10 |
| IL195174A0 (en) | 2009-08-03 |
| AU2006343077A1 (en) | 2007-11-15 |
| EP2016939A4 (en) | 2013-01-09 |
| KR20090009951A (ko) | 2009-01-23 |
| JPWO2007129427A1 (ja) | 2009-09-17 |
| US7858114B2 (en) | 2010-12-28 |
| BRPI0621655A2 (pt) | 2011-12-20 |
| US20070259028A1 (en) | 2007-11-08 |
| CN101460156B (zh) | 2011-06-08 |
| HK1130175A1 (en) | 2009-12-24 |
| EP2016939A1 (en) | 2009-01-21 |
| JP5122445B2 (ja) | 2013-01-16 |
| CA2651596C (en) | 2014-03-25 |
| MY149152A (en) | 2013-07-15 |
| CN101460156A (zh) | 2009-06-17 |
| IN266817B (https=) | 2015-06-03 |
| NO20084614L (no) | 2009-02-06 |
| EP2016939B1 (en) | 2014-03-19 |
| AU2006343077B2 (en) | 2012-11-08 |
| CA2651596A1 (en) | 2007-11-15 |
| WO2007129427A1 (ja) | 2007-11-15 |
| ES2466647T3 (es) | 2014-06-10 |
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