JP5016926B2 - 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法 - Google Patents

架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法 Download PDF

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Publication number
JP5016926B2
JP5016926B2 JP2006547530A JP2006547530A JP5016926B2 JP 5016926 B2 JP5016926 B2 JP 5016926B2 JP 2006547530 A JP2006547530 A JP 2006547530A JP 2006547530 A JP2006547530 A JP 2006547530A JP 5016926 B2 JP5016926 B2 JP 5016926B2
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gel
solution
dvs
polymer
ipc
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Japanese (ja)
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JP2007519779A (ja
Inventor
アデルヤ ケイ． レシチナー
ポール エー． コノウィッツ
バレンチナ バシリーバ
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Genzyme Corp
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Genzyme Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2006547530A 2003-12-30 2004-12-30 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法 Expired - Lifetime JP5016926B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53342903P 2003-12-30 2003-12-30
US60/533,429 2003-12-30
PCT/US2004/043811 WO2005066215A1 (en) 2003-12-30 2004-12-30 Cohesive gels form cross-linked hyaluronan and/or hylan, their preparation and use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011169777A Division JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法

Publications (2)

Publication Number Publication Date
JP2007519779A JP2007519779A (ja) 2007-07-19
JP5016926B2 true JP5016926B2 (ja) 2012-09-05

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JP2006547530A Expired - Lifetime JP5016926B2 (ja) 2003-12-30 2004-12-30 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法
JP2011169777A Expired - Lifetime JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法

Family Applications After (1)

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JP2011169777A Expired - Lifetime JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび／またはハイランに由来する粘着性ゲル、その調製および使用法

Country Status (10)

Country Link
US (1) US20050142152A1 (cg-RX-API-DMAC7.html)
EP (1) EP1701981B1 (cg-RX-API-DMAC7.html)
JP (2) JP5016926B2 (cg-RX-API-DMAC7.html)
CN (1) CN100537606C (cg-RX-API-DMAC7.html)
AU (1) AU2004312532B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0418309B8 (cg-RX-API-DMAC7.html)
CA (1) CA2550718C (cg-RX-API-DMAC7.html)
IL (1) IL176465A (cg-RX-API-DMAC7.html)
MX (1) MXPA06007556A (cg-RX-API-DMAC7.html)
WO (1) WO2005066215A1 (cg-RX-API-DMAC7.html)

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Publication number Publication date
US20050142152A1 (en) 2005-06-30
AU2004312532A1 (en) 2005-07-21
JP2007519779A (ja) 2007-07-19
CN1902232A (zh) 2007-01-24
EP1701981A1 (en) 2006-09-20
JP2012025955A (ja) 2012-02-09
IL176465A (en) 2013-07-31
CA2550718A1 (en) 2005-07-21
IL176465A0 (en) 2006-10-05
WO2005066215A1 (en) 2005-07-21
BRPI0418309B8 (pt) 2021-05-25
EP1701981B1 (en) 2017-06-07
CN100537606C (zh) 2009-09-09
MXPA06007556A (es) 2006-08-31
AU2004312532B2 (en) 2010-05-20
CA2550718C (en) 2013-11-05
BRPI0418309B1 (pt) 2016-08-02
BRPI0418309A (pt) 2007-05-02
JP5680501B2 (ja) 2015-03-04

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