JP4988131B2 - 血小板のコラーゲンへの粘着を抑制するための新規な特異的機構 - Google Patents
血小板のコラーゲンへの粘着を抑制するための新規な特異的機構 Download PDFInfo
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- JP4988131B2 JP4988131B2 JP2002520840A JP2002520840A JP4988131B2 JP 4988131 B2 JP4988131 B2 JP 4988131B2 JP 2002520840 A JP2002520840 A JP 2002520840A JP 2002520840 A JP2002520840 A JP 2002520840A JP 4988131 B2 JP4988131 B2 JP 4988131B2
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- saratin
- collagen
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- endarterectomy
- blood
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
Landscapes
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- Engineering & Computer Science (AREA)
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- Pharmacology & Pharmacy (AREA)
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Applications Claiming Priority (3)
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| EP00118542 | 2000-08-25 | ||
| EP00118542.0 | 2000-08-25 | ||
| PCT/EP2001/009746 WO2002015919A2 (en) | 2000-08-25 | 2001-08-23 | Saratin for inhibiting platelet adhesion to collagen |
Publications (3)
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| JP2004506690A JP2004506690A (ja) | 2004-03-04 |
| JP2004506690A5 JP2004506690A5 (OSRAM) | 2008-10-09 |
| JP4988131B2 true JP4988131B2 (ja) | 2012-08-01 |
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| MX (1) | MXPA03001604A (OSRAM) |
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| SI (1) | SI1311284T1 (OSRAM) |
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| UA (1) | UA77402C2 (OSRAM) |
| WO (1) | WO2002015919A2 (OSRAM) |
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| MXPA05006043A (es) | 2003-01-10 | 2006-01-30 | Ablynx Nv | Polipeptidos terapeuticos, homologos de los mismos, fragmentos de los mismos y para uso al modular la agregacion mediada de plaquetas. |
| US7691839B2 (en) | 2005-09-28 | 2010-04-06 | Biovascular, Inc. | Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation |
| US20110034396A1 (en) * | 2005-09-28 | 2011-02-10 | Biovascular, Inc. | Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions |
| US20080069774A1 (en) * | 2005-11-17 | 2008-03-20 | Lance Liotta | Proteomic antisense molecular shield and targeting |
| EP3846867B1 (en) * | 2018-09-06 | 2025-02-19 | Biomodics APS | A medical tubular device |
| CN117229423B (zh) * | 2023-11-10 | 2024-02-06 | 北京科技大学 | 一种用于结合胶原的多肽纳米材料及其制备方法和应用 |
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| US3947401A (en) * | 1971-10-05 | 1976-03-30 | Union Optics Corporation | Hydrogels of unsaturated ester copolymers |
| US5705355A (en) | 1984-03-27 | 1998-01-06 | Transgene, S.A. | Hirudin, pharmaceutical compositions comprising it and their use |
| US4879135A (en) * | 1984-07-23 | 1989-11-07 | University Of Medicine And Dentistry Of New Jersey | Drug bonded prosthesis and process for producing same |
| US4898734A (en) * | 1988-02-29 | 1990-02-06 | Massachusetts Institute Of Technology | Polymer composite for controlled release or membrane formation |
| IL86857A (en) * | 1988-06-24 | 1994-04-12 | Yissum Res Dev Co | Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same |
| US5304121A (en) * | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| CA2052486A1 (en) * | 1990-10-09 | 1992-04-10 | Thomas M. Connolly | Protein for inhibiting collagen-stimulated platelet aggregation |
| GB9022040D0 (en) | 1990-10-10 | 1990-11-21 | Biopharm Ltd | Platelet adhesion inhibitor |
| US5179082A (en) * | 1990-11-13 | 1993-01-12 | Merck & Co., Inc. | Method for blocking platelet adhesion to collagen |
| ATE169674T1 (de) * | 1991-09-05 | 1998-08-15 | Schering Ag | Hemmstoff der kollagen-induzierten plättchenaggregation |
| DE4136513A1 (de) | 1991-11-06 | 1993-05-13 | Basf Ag | Neues thrombininhibitorisches protein aus raubwanzen |
| JP3742429B2 (ja) | 1993-07-01 | 2006-02-01 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | コラーゲン刺激血小板凝集の阻害剤 |
| ES2255477T5 (es) * | 1993-07-29 | 2010-04-08 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Uso de paclitaxel y sus derivados en la fabricacion de un medicamento para el tratamiento de reestenosis. |
| US5532287A (en) * | 1994-05-04 | 1996-07-02 | Ciba-Geigy Corporation | Radiation cured drug release controlling membrane |
| US5767108A (en) * | 1995-08-22 | 1998-06-16 | Medtronic, Inc. | Method for making improved heparinized biomaterials |
| US6246715B1 (en) * | 1998-06-26 | 2001-06-12 | Samsung Electronics Co., Ltd. | Data transmitter and receiver of a DS-CDMA communication system |
| US5843172A (en) * | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
| WO2000023094A2 (en) * | 1998-10-16 | 2000-04-27 | Immunex Corporation | Methods of inhibiting platelet activation and recruitment |
| IT1304135B1 (it) * | 1998-11-26 | 2001-03-07 | Magneti Marelli Spa | Metodo di controllo dell' iniezione e dell' accensione in un motoreendotermico ad iniezione diretta per accelerare il riscaldamento del |
| JP2002537270A (ja) * | 1999-02-19 | 2002-11-05 | ザイモジェネティクス，インコーポレイティド | 止血及び免疫機能における使用のためのインヒビター |
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