NO20030841L - En ny spesifikk mekanisme for inhibering av blodplateadhesjon til kollagen - Google Patents

En ny spesifikk mekanisme for inhibering av blodplateadhesjon til kollagen

Info

Publication number
NO20030841L
NO20030841L NO20030841A NO20030841A NO20030841L NO 20030841 L NO20030841 L NO 20030841L NO 20030841 A NO20030841 A NO 20030841A NO 20030841 A NO20030841 A NO 20030841A NO 20030841 L NO20030841 L NO 20030841L
Authority
NO
Norway
Prior art keywords
platelet adhesion
collagen
inhibition
specific mechanism
new specific
Prior art date
Application number
NO20030841A
Other languages
English (en)
Other versions
NO331326B1 (no
NO20030841D0 (no
Inventor
Christopher Barnes
Matthias Frech
Uwe Hoffmann
Johannes Gleitz
Wolfgang Strittmatter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20030841D0 publication Critical patent/NO20030841D0/no
Publication of NO20030841L publication Critical patent/NO20030841L/no
Publication of NO331326B1 publication Critical patent/NO331326B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Anvendelse av polypeptidet saratin til fremstilling av et medikament som har evne til signifikant å redusere blodplateadhesjon og blodplateakkumulering etter vaskulære skader eller endarterektomi. Oppfinnelsen vedrører dessuten en ny medisinsk anvendelse av saratin som en inhibitor for trombose og intimal hyper-plasi, hvor polypeptidet kan anvendes lokalt som et topisk middel eller som et belegg på, eller på annen måte inkorporert i eller forbundet med, medisinske anordninger.
NO20030841A 2000-08-25 2003-02-24 Anvendelse av saratin til fremstilling av et medikament for inhibering av blodplateadhesjon til kollagen NO331326B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00118542 2000-08-25
PCT/EP2001/009746 WO2002015919A2 (en) 2000-08-25 2001-08-23 Saratin for inhibiting platelet adhesion to collagen

Publications (3)

Publication Number Publication Date
NO20030841D0 NO20030841D0 (no) 2003-02-24
NO20030841L true NO20030841L (no) 2003-02-24
NO331326B1 NO331326B1 (no) 2011-11-28

Family

ID=8169664

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030841A NO331326B1 (no) 2000-08-25 2003-02-24 Anvendelse av saratin til fremstilling av et medikament for inhibering av blodplateadhesjon til kollagen

Country Status (27)

Country Link
US (2) US6881722B2 (no)
EP (1) EP1311284B1 (no)
JP (1) JP4988131B2 (no)
KR (1) KR100794277B1 (no)
CN (1) CN1224421C (no)
AR (1) AR030492A1 (no)
AT (1) ATE285246T1 (no)
AU (2) AU2001295506B2 (no)
BR (1) BR0113478A (no)
CA (1) CA2419385C (no)
CZ (1) CZ302353B6 (no)
DE (1) DE60107962T2 (no)
DK (1) DK1311284T3 (no)
EC (1) ECSP034485A (no)
ES (1) ES2234896T3 (no)
HK (1) HK1059736A1 (no)
HU (1) HU229367B1 (no)
MX (1) MXPA03001604A (no)
MY (1) MY128992A (no)
NO (1) NO331326B1 (no)
PT (1) PT1311284E (no)
RU (1) RU2302880C2 (no)
SI (1) SI1311284T1 (no)
SK (1) SK287829B6 (no)
UA (1) UA77402C2 (no)
WO (1) WO2002015919A2 (no)
ZA (1) ZA200302296B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1161530B1 (en) * 1999-03-18 2005-05-18 MERCK PATENT GmbH Protein for blocking platelet adhesion
CN101412759A (zh) 2003-01-10 2009-04-22 埃博灵克斯股份有限公司 治疗性多肽,其同源物、其片段及其在调节血小板介导的聚集方面的应用
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions
WO2007038749A2 (en) 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20080069774A1 (en) * 2005-11-17 2008-03-20 Lance Liotta Proteomic antisense molecular shield and targeting
CN113038976A (zh) * 2018-09-06 2021-06-25 比奥莫迪克斯有限公司 医疗管状装置
CN117229423B (zh) * 2023-11-10 2024-02-06 北京科技大学 一种用于结合胶原的多肽纳米材料及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947401A (en) * 1971-10-05 1976-03-30 Union Optics Corporation Hydrogels of unsaturated ester copolymers
US5705355A (en) * 1984-03-27 1998-01-06 Transgene, S.A. Hirudin, pharmaceutical compositions comprising it and their use
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5304121A (en) * 1990-12-28 1994-04-19 Boston Scientific Corporation Drug delivery system making use of a hydrogel polymer coating
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
GB9022040D0 (en) * 1990-10-10 1990-11-21 Biopharm Ltd Platelet adhesion inhibitor
US5179082A (en) * 1990-11-13 1993-01-12 Merck & Co., Inc. Method for blocking platelet adhesion to collagen
DE4136513A1 (de) 1991-11-06 1993-05-13 Basf Ag Neues thrombininhibitorisches protein aus raubwanzen
CZ287472B6 (en) * 1993-07-01 2000-12-13 Merck Patent Gmbh Purified protein, process of its preparation and use as well as pharmaceutical preparation based thereon
WO1995003795A1 (en) * 1993-07-29 1995-02-09 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method of treating atherosclerosis or restenosis using microtubule stabilizing agent
US5532287A (en) * 1994-05-04 1996-07-02 Ciba-Geigy Corporation Radiation cured drug release controlling membrane
US6246715B1 (en) * 1998-06-26 2001-06-12 Samsung Electronics Co., Ltd. Data transmitter and receiver of a DS-CDMA communication system
US5843172A (en) * 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
WO2000023094A2 (en) * 1998-10-16 2000-04-27 Immunex Corporation Methods of inhibiting platelet activation and recruitment
IT1304135B1 (it) * 1998-11-26 2001-03-07 Magneti Marelli Spa Metodo di controllo dell' iniezione e dell' accensione in un motoreendotermico ad iniezione diretta per accelerare il riscaldamento del
EP1382345A3 (en) * 1999-02-19 2004-01-28 Zymogenetics Inc Uses of inhibitors of hemostasis
EP1161530B1 (en) * 1999-03-18 2005-05-18 MERCK PATENT GmbH Protein for blocking platelet adhesion

Also Published As

Publication number Publication date
BR0113478A (pt) 2003-07-15
JP2004506690A (ja) 2004-03-04
US6881722B2 (en) 2005-04-19
HK1059736A1 (en) 2004-07-16
EP1311284A2 (en) 2003-05-21
ECSP034485A (es) 2003-03-31
WO2002015919A2 (en) 2002-02-28
SK3132003A3 (en) 2003-08-05
US20030190342A1 (en) 2003-10-09
PL359246A1 (en) 2004-08-23
DK1311284T3 (da) 2005-04-18
AR030492A1 (es) 2003-08-20
ATE285246T1 (de) 2005-01-15
SI1311284T1 (no) 2005-08-31
DE60107962D1 (de) 2005-01-27
HUP0303747A3 (en) 2006-01-30
US7459438B2 (en) 2008-12-02
CN1449291A (zh) 2003-10-15
CN1224421C (zh) 2005-10-26
WO2002015919A3 (en) 2002-05-30
EP1311284B1 (en) 2004-12-22
PT1311284E (pt) 2005-05-31
NO331326B1 (no) 2011-11-28
ES2234896T3 (es) 2005-07-01
NO20030841D0 (no) 2003-02-24
JP4988131B2 (ja) 2012-08-01
CZ2003720A3 (cs) 2003-06-18
DE60107962T2 (de) 2005-12-15
US20050143305A1 (en) 2005-06-30
MXPA03001604A (es) 2003-06-04
UA77402C2 (en) 2006-12-15
ZA200302296B (en) 2004-06-30
AU2001295506B2 (en) 2007-02-15
SK287829B6 (sk) 2011-11-04
RU2302880C2 (ru) 2007-07-20
MY128992A (en) 2007-03-30
CA2419385C (en) 2011-05-10
HU229367B1 (en) 2013-11-28
CZ302353B6 (cs) 2011-03-30
HUP0303747A2 (hu) 2004-03-01
CA2419385A1 (en) 2002-02-28
KR20030034141A (ko) 2003-05-01
AU9550601A (en) 2002-03-04
KR100794277B1 (ko) 2008-01-11

Similar Documents

Publication Publication Date Title
AU2002302587A1 (en) Acne treatment with lipooxigenase inhibitors
WO2002089743A3 (en) Use of compositions for treating rosacea
PA8506101A1 (es) Uso de un compuesto acat para fabricar una composicion farmaceutica
NO20013966L (no) Kombinasjoner for behandling av sykdommer som involverer angiogenese
CY1110289T1 (el) Φαρμακευτικη συνθεση για τη θεραπεια ρινιτιδων
BRPI0110506B8 (pt) uso de inibidores de il-18 para o tratamento e/ou prevenção da aterosclerose
UY25321A1 (es) Combinaciones de inhibidor de ace-inhibidor de mmp
NO20030841L (no) En ny spesifikk mekanisme for inhibering av blodplateadhesjon til kollagen
DE50109226D1 (de) Dermales therapeutisches system enthaltend nichtsteroidale antiphlogistika mit selektiver cox-2-hemmung
BR9807523A (pt) Quinoxalinas em combinação tripla com inibidores da protease e inibidores de transcriptase reversa como medicamentos para o tratamento de aids.
SE9600216D0 (sv) Styrning av läkningsprocesser
BR0315455A (pt) Composição farmacêutica para o tratamento de manifestações dolorosas e inflamatórios e utilização combinada do tenatoprazol e de pelo menos um antiinflamatório
RS51534B (en) NEW COMPOUND OF SINUSOID IF CURRENT INHIBITORS AND CALCIUM INHIBITOR AND PHARMACEUTICAL MIXTURE CONTAINED BY IT
BR0108980A (pt) Aplicação e formulação farmacêuticas compreendendo inibidor de reabsorção de norepinefrina
NO20004920L (no) Anvendelse av proteaseinhibitorer for behandling av hudsår
WO2004045534A3 (en) Chroman derivatives for the reduction of inflammation symptoms
EE9700350A (et) COMT-inhibiitorite uus kasutamine ja diabeetiliste vaskulaarsete häirete ärahoidmise meetod
ES2196769T3 (es) Uso topico de loperamide para el tratamiento de infecciones microbianas.
EP1459763A4 (en) MEDICAMENT FOR PREVENTING VEGETABLE RESTENOSIS AND INSTRUMENT FOR EMBEDDING IN A VESSEL DIRECTED WITH THE MEDICINAL PRODUCT
IT1317745B1 (it) Composizione a base di acido acetilsacilico per la prevenzioneprimaria della trombosi ed altri eventi cardiocerebrovascolari.
ECSP982806A (es) Combinaciones de inhibidor de ace- inhibidor de mmp

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees