JP4970069B2 - 視覚再生補助装置 - Google Patents
視覚再生補助装置 Download PDFInfo
- Publication number
- JP4970069B2 JP4970069B2 JP2007020117A JP2007020117A JP4970069B2 JP 4970069 B2 JP4970069 B2 JP 4970069B2 JP 2007020117 A JP2007020117 A JP 2007020117A JP 2007020117 A JP2007020117 A JP 2007020117A JP 4970069 B2 JP4970069 B2 JP 4970069B2
- Authority
- JP
- Japan
- Prior art keywords
- signal
- control unit
- electrical stimulation
- electrode
- stimulation pulse
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000000007 visual effect Effects 0.000 title claims description 24
- 230000000638 stimulation Effects 0.000 claims description 84
- 210000001124 body fluid Anatomy 0.000 claims description 24
- 239000010839 body fluid Substances 0.000 claims description 24
- 230000005540 biological transmission Effects 0.000 claims description 12
- 239000004020 conductor Substances 0.000 claims description 7
- 239000000284 extract Substances 0.000 claims description 6
- 239000011347 resin Substances 0.000 claims description 6
- 229920005989 resin Polymers 0.000 claims description 6
- 238000009413 insulation Methods 0.000 claims description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 27
- 238000001727 in vivo Methods 0.000 description 19
- 210000001525 retina Anatomy 0.000 description 16
- 239000000758 substrate Substances 0.000 description 15
- 210000004027 cell Anatomy 0.000 description 13
- 210000001508 eye Anatomy 0.000 description 13
- 239000000463 material Substances 0.000 description 12
- 238000009434 installation Methods 0.000 description 10
- 229910052697 platinum Inorganic materials 0.000 description 10
- 238000010586 diagram Methods 0.000 description 8
- 238000005868 electrolysis reaction Methods 0.000 description 8
- 230000004936 stimulating effect Effects 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 210000003786 sclera Anatomy 0.000 description 5
- 239000003990 capacitor Substances 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000002123 temporal effect Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 230000002051 biphasic effect Effects 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000004065 semiconductor Substances 0.000 description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 210000003710 cerebral cortex Anatomy 0.000 description 2
- 210000003161 choroid Anatomy 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 230000002427 irreversible effect Effects 0.000 description 2
- 210000001328 optic nerve Anatomy 0.000 description 2
- 210000004279 orbit Anatomy 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical compound [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 description 2
- 229920000052 poly(p-xylylene) Polymers 0.000 description 2
- 239000010970 precious metal Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 201000004569 Blindness Diseases 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 229910001260 Pt alloy Inorganic materials 0.000 description 1
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- HTXDPTMKBJXEOW-UHFFFAOYSA-N dioxoiridium Chemical compound O=[Ir]=O HTXDPTMKBJXEOW-UHFFFAOYSA-N 0.000 description 1
- 239000007772 electrode material Substances 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 229910000457 iridium oxide Inorganic materials 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000001465 metallisation Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 210000000869 occipital lobe Anatomy 0.000 description 1
- 210000003977 optic chiasm Anatomy 0.000 description 1
- 210000003733 optic disk Anatomy 0.000 description 1
- 230000010363 phase shift Effects 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 210000002763 pyramidal cell Anatomy 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 210000000857 visual cortex Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007020117A JP4970069B2 (ja) | 2007-01-30 | 2007-01-30 | 視覚再生補助装置 |
| US12/022,374 US7941222B2 (en) | 2007-01-30 | 2008-01-30 | Vision regeneration assisting apparatus |
| EP08001725.4A EP1958661B1 (en) | 2007-01-30 | 2008-01-30 | Vision regeneration assisting apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007020117A JP4970069B2 (ja) | 2007-01-30 | 2007-01-30 | 視覚再生補助装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008183248A JP2008183248A (ja) | 2008-08-14 |
| JP2008183248A5 JP2008183248A5 (enExample) | 2010-03-11 |
| JP4970069B2 true JP4970069B2 (ja) | 2012-07-04 |
Family
ID=39327233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007020117A Active JP4970069B2 (ja) | 2007-01-30 | 2007-01-30 | 視覚再生補助装置 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US7941222B2 (enExample) |
| EP (1) | EP1958661B1 (enExample) |
| JP (1) | JP4970069B2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010057643A (ja) * | 2008-09-02 | 2010-03-18 | Nidek Co Ltd | 視覚再生補助装置 |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5405848B2 (ja) * | 2009-02-16 | 2014-02-05 | 株式会社ニデック | 視覚再生補助装置 |
| US20100268309A1 (en) | 2009-04-17 | 2010-10-21 | Boston Scientific Neuromodulation Corporation | Architectures for Multi-Electrode Implantable Stimulator Devices Having Minimal Numbers of Decoupling Capacitors |
| JP5545962B2 (ja) * | 2010-02-16 | 2014-07-09 | 株式会社ニデック | 視覚再生補助装置 |
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| CA2817589A1 (en) | 2010-11-16 | 2012-05-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for treatment of dry eye |
| CN102793592B (zh) * | 2012-08-09 | 2014-09-10 | 上海交通大学 | 一种具有扇形贴附功能的视神经可植入神经接口装置 |
| US9265956B2 (en) | 2013-03-08 | 2016-02-23 | Oculeve, Inc. | Devices and methods for treating dry eye in animals |
| EP2967817B1 (en) | 2013-03-12 | 2021-03-10 | Oculeve, Inc. | Implant delivery devices and systems |
| HK1220934A1 (zh) | 2013-04-19 | 2017-05-19 | Oculeve, Inc. | 鼻刺激装置和方法 |
| CN104225785B (zh) * | 2013-06-20 | 2018-11-16 | 苏州六六视觉科技股份有限公司 | 用于治疗视觉系统疾病的治疗装置 |
| CN103816006B (zh) * | 2014-02-20 | 2016-01-20 | 深圳市上示科技有限公司 | 一种非植入性经人体体表激发盲人视觉感受的设备 |
| JP6604963B2 (ja) | 2014-02-25 | 2019-11-20 | オキュリーブ, インコーポレイテッド | 鼻涙腺刺激のためのポリマー配合物 |
| JP6643313B2 (ja) | 2014-07-25 | 2020-02-12 | オキュリーブ, インコーポレイテッド | ドライアイを治療するための刺激パターン |
| KR20170074926A (ko) | 2014-10-22 | 2017-06-30 | 오큘레브, 인크. | 안구 건조증을 치료하기 위한 자극 장치 및 방법 |
| WO2016065213A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Implantable nasal stimulator systems and methods |
| CA2965514A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Contact lens for increasing tear production |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| US10918864B2 (en) | 2016-05-02 | 2021-02-16 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| CA3045018A1 (en) | 2016-12-02 | 2018-06-07 | Oculeve, Inc. | Apparatus and method for dry eye forecast and treatment recommendation |
| WO2020072468A1 (en) * | 2018-10-01 | 2020-04-09 | Biovisics Medical, Llc | System and methods for controlled electrical modulation for vision therapy |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6442431B1 (en) | 1998-07-27 | 2002-08-27 | Axon Engineering, Inc., | Device and method for production of visual sensations by optic nerve stimulation |
| EP1171188B1 (en) * | 1999-03-24 | 2009-05-06 | Second Sight Medical Products, Inc. | Retinal color prosthesis for color sight restoration |
| UA78672C2 (en) * | 1999-04-09 | 2007-04-25 | Kevin R Orton | Method for preparation and use of conductive medicinal substance (variants) |
| JP4781576B2 (ja) * | 2001-02-28 | 2011-09-28 | 株式会社ニデック | 眼内埋め込み型視覚刺激装置 |
| JP2004057628A (ja) | 2002-07-31 | 2004-02-26 | Nidek Co Ltd | 視覚再生補助装置 |
| US6920361B2 (en) * | 2003-02-14 | 2005-07-19 | Medtronic, Inc. | Reverse wound electrodes |
| TW200531716A (en) * | 2004-03-19 | 2005-10-01 | Skylark Device & Systems Co Ltd | Method and apparatus for applying microcurrent into eyes |
| US7263403B2 (en) * | 2004-05-25 | 2007-08-28 | Second Sight Medical Products, Inc. | Retinal prosthesis |
| JP4546184B2 (ja) | 2004-08-04 | 2010-09-15 | 株式会社ニデック | 整流回路及びこれを備えた視覚再生補助装置 |
| JP4767571B2 (ja) * | 2005-03-31 | 2011-09-07 | 株式会社ニデック | 視覚再生補助装置 |
| JP2006280412A (ja) | 2005-03-31 | 2006-10-19 | Nidek Co Ltd | 視覚再生補助装置及び該装置の製造方法 |
| JP2007044323A (ja) | 2005-08-11 | 2007-02-22 | Nidek Co Ltd | 視覚再生補助装置 |
-
2007
- 2007-01-30 JP JP2007020117A patent/JP4970069B2/ja active Active
-
2008
- 2008-01-30 US US12/022,374 patent/US7941222B2/en not_active Expired - Fee Related
- 2008-01-30 EP EP08001725.4A patent/EP1958661B1/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010057643A (ja) * | 2008-09-02 | 2010-03-18 | Nidek Co Ltd | 視覚再生補助装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7941222B2 (en) | 2011-05-10 |
| JP2008183248A (ja) | 2008-08-14 |
| EP1958661A1 (en) | 2008-08-20 |
| US20080183243A1 (en) | 2008-07-31 |
| EP1958661B1 (en) | 2015-03-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4970069B2 (ja) | 視覚再生補助装置 | |
| US11393247B2 (en) | Face detection tracking and recognition for a visual prosthesis | |
| JP5578540B2 (ja) | 視覚再生補助装置及び視覚再生補助装置の製造方法 | |
| EP2900316B1 (en) | Medical device comprising an implantable coil, an external coil and a signal strength indicator | |
| US7398124B2 (en) | Visual restoration aiding device | |
| JP5405848B2 (ja) | 視覚再生補助装置 | |
| EP2460559B1 (en) | Living tissue stimulation apparatus | |
| US20250221650A1 (en) | System for powering and controlling the electronics of minimally invasive stimulation or monitoring devices implantable in head or neck body regions | |
| JP5122244B2 (ja) | 視覚再生補助装置 | |
| JP5188792B2 (ja) | 視覚再生補助装置 | |
| JP5219443B2 (ja) | 視覚再生補助装置用の刺激ユニットの作製方法 | |
| JP6048053B2 (ja) | 生体組織刺激装置 | |
| JP2009082496A (ja) | 視覚再生補助装置 | |
| JP5265209B2 (ja) | 視覚再生補助装置 | |
| JP5242177B2 (ja) | 視覚再生補助装置 | |
| JP2020081720A (ja) | 視覚再生補助装置 | |
| JP2008245834A (ja) | 視覚再生補助装置及び視覚再生補助装置の導線接続方法 | |
| JP5179228B2 (ja) | 通信回路及びこれを備えた視覚再生補助装置 | |
| JP2009066237A (ja) | 視覚再生補助装置 | |
| JP5284014B2 (ja) | 視覚再生補助装置 | |
| JP2011101692A (ja) | 視覚再生補助装置 | |
| JP2009268834A (ja) | 視覚再生補助装置 | |
| JP2007097630A (ja) | 視覚再生補助装置 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100122 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20100122 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20111115 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20111122 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120123 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20120306 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120404 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150413 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 Ref document number: 4970069 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |