JP4819697B2 - 胚体内胚葉 - Google Patents

胚体内胚葉 Download PDF

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Publication number
JP4819697B2
JP4819697B2 JP2006547496A JP2006547496A JP4819697B2 JP 4819697 B2 JP4819697 B2 JP 4819697B2 JP 2006547496 A JP2006547496 A JP 2006547496A JP 2006547496 A JP2006547496 A JP 2006547496A JP 4819697 B2 JP4819697 B2 JP 4819697B2
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cells
cell
definitive endoderm
human
sox17
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JP2007516728A (ja
JP2007516728A5 (cg-RX-API-DMAC7.html
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ケビン アレン ダムール
アラン ディー アグルニック
エマニュエル イー べェツゲ
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ヴィアサイト，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2006547496A 2003-12-23 2004-12-23 胚体内胚葉 Expired - Lifetime JP4819697B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US53200403P 2003-12-23 2003-12-23
US60/532,004 2003-12-23
US58656604P 2004-07-09 2004-07-09
US60/586,566 2004-07-09
US58794204P 2004-07-14 2004-07-14
US60/587,942 2004-07-14
PCT/US2004/043696 WO2005063971A2 (en) 2003-12-23 2004-12-23 Definitive endoderm

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011168363A Division JP5669688B2 (ja) 2003-12-23 2011-08-01 胚体内胚葉

Publications (3)

Publication Number Publication Date
JP2007516728A JP2007516728A (ja) 2007-06-28
JP2007516728A5 JP2007516728A5 (cg-RX-API-DMAC7.html) 2010-08-12
JP4819697B2 true JP4819697B2 (ja) 2011-11-24

Family

ID=34743694

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2006547496A Expired - Lifetime JP4819697B2 (ja) 2003-12-23 2004-12-23 胚体内胚葉
JP2011168363A Expired - Lifetime JP5669688B2 (ja) 2003-12-23 2011-08-01 胚体内胚葉
JP2014186172A Expired - Lifetime JP6356021B2 (ja) 2003-12-23 2014-09-12 胚体内胚葉
JP2015111659A Pending JP2015163081A (ja) 2003-12-23 2015-06-01 胚体内胚葉
JP2016232292A Expired - Lifetime JP6574158B2 (ja) 2003-12-23 2016-11-30 胚体内胚葉
JP2018130280A Pending JP2018171071A (ja) 2003-12-23 2018-07-09 胚体内胚葉
JP2020032178A Expired - Lifetime JP7045407B2 (ja) 2003-12-23 2020-02-27 胚体内胚葉

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2011168363A Expired - Lifetime JP5669688B2 (ja) 2003-12-23 2011-08-01 胚体内胚葉
JP2014186172A Expired - Lifetime JP6356021B2 (ja) 2003-12-23 2014-09-12 胚体内胚葉
JP2015111659A Pending JP2015163081A (ja) 2003-12-23 2015-06-01 胚体内胚葉
JP2016232292A Expired - Lifetime JP6574158B2 (ja) 2003-12-23 2016-11-30 胚体内胚葉
JP2018130280A Pending JP2018171071A (ja) 2003-12-23 2018-07-09 胚体内胚葉
JP2020032178A Expired - Lifetime JP7045407B2 (ja) 2003-12-23 2020-02-27 胚体内胚葉

Country Status (15)

Country Link
US (8) US7704738B2 (cg-RX-API-DMAC7.html)
EP (2) EP2722387B1 (cg-RX-API-DMAC7.html)
JP (7) JP4819697B2 (cg-RX-API-DMAC7.html)
KR (1) KR101221302B1 (cg-RX-API-DMAC7.html)
CN (2) CN103898045B (cg-RX-API-DMAC7.html)
AU (2) AU2004309421B2 (cg-RX-API-DMAC7.html)
CA (2) CA2549605C (cg-RX-API-DMAC7.html)
DK (2) DK1709159T3 (cg-RX-API-DMAC7.html)
EA (1) EA200601231A1 (cg-RX-API-DMAC7.html)
HK (3) HK1197082A1 (cg-RX-API-DMAC7.html)
IL (1) IL176336A (cg-RX-API-DMAC7.html)
MX (2) MXPA06007252A (cg-RX-API-DMAC7.html)
NZ (1) NZ547920A (cg-RX-API-DMAC7.html)
SG (1) SG149061A1 (cg-RX-API-DMAC7.html)
WO (1) WO2005063971A2 (cg-RX-API-DMAC7.html)

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