JP4728485B2 - 多環式チアゾール系および食欲抑制剤としてのその使用 - Google Patents

多環式チアゾール系および食欲抑制剤としてのその使用 Download PDF

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Publication number
JP4728485B2
JP4728485B2 JP2000602224A JP2000602224A JP4728485B2 JP 4728485 B2 JP4728485 B2 JP 4728485B2 JP 2000602224 A JP2000602224 A JP 2000602224A JP 2000602224 A JP2000602224 A JP 2000602224A JP 4728485 B2 JP4728485 B2 JP 4728485B2
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alkyl
phenyl
conh
ocf
substituted
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JP2000602224A
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Japanese (ja)
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JP2002538150A (ja
JP2002538150A5 (https=
Inventor
ゲーアハルト・イェーネ
カール・ガイゼン
ハンス−ヨッヘン・ラング
マルティン・ビッケル
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84—Naphthothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2000602224A 1999-02-26 2000-02-05 多環式チアゾール系および食欲抑制剤としてのその使用 Expired - Fee Related JP4728485B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19908533.1 1999-02-26
DE19908533A DE19908533A1 (de) 1999-02-26 1999-02-26 Polycyclische Thiazol-Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen
PCT/EP2000/000927 WO2000051997A1 (de) 1999-02-26 2000-02-05 Polycyclische thiazol-systeme und ihre verwendung als anorektika

Publications (3)

Publication Number Publication Date
JP2002538150A JP2002538150A (ja) 2002-11-12
JP2002538150A5 JP2002538150A5 (https=) 2007-03-29
JP4728485B2 true JP4728485B2 (ja) 2011-07-20

Family

ID=7899078

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000602224A Expired - Fee Related JP4728485B2 (ja) 1999-02-26 2000-02-05 多環式チアゾール系および食欲抑制剤としてのその使用

Country Status (19)

Country Link
US (1) US6187801B1 (https=)
EP (1) EP1183247B1 (https=)
JP (1) JP4728485B2 (https=)
KR (1) KR20020000545A (https=)
CN (1) CN1149205C (https=)
AT (1) ATE296295T1 (https=)
AU (1) AU762802B2 (https=)
BR (1) BR0008511A (https=)
CA (1) CA2364903A1 (https=)
CO (1) CO5180595A1 (https=)
DE (2) DE19908533A1 (https=)
DK (1) DK1183247T3 (https=)
ES (1) ES2241574T3 (https=)
HK (1) HK1042300B (https=)
MY (1) MY133195A (https=)
PT (1) PT1183247E (https=)
TW (1) TW593294B (https=)
WO (1) WO2000051997A1 (https=)
ZA (1) ZA200106440B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
KR100763214B1 (ko) * 2000-02-26 2007-10-08 사노피-아벤티스 도이칠란트 게엠베하 2 위치에서 설폰아미도 또는 설포노 치환체를 갖는 8,8ａ-디하이드로-인데노[1,2-ｄ]티아졸 유도체, 이의 제조방법 및 이를 포함하는 약제
DE10142663B4 (de) 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
KR100712171B1 (ko) * 2004-09-17 2007-05-02 김진우 폐타이어를 이용한 조립식 배관블록
ES2480994T3 (es) 2008-03-31 2014-07-29 Genentech, Inc. Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso
ES2558742T3 (es) 2009-09-28 2016-02-08 F. Hoffmann-La Roche Ag Compuestos inhibidores de PI3K de benzoxepina y métodos de uso
ES2570569T3 (es) 2009-09-28 2016-05-19 Hoffmann La Roche Compuestos de benzoxazepina como inhibidores de la PI3K y métodos de uso
WO2012126901A1 (en) 2011-03-21 2012-09-27 F. Hoffmann-La Roche Ag Benzoxazepin compounds selective for pi3k p110 delta and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
NZ281718A (en) * 1994-03-11 1997-08-22 Yamanouchi Pharma Co Ltd Heterocyclically-substituted (condensed) thiazoles
JPH1179993A (ja) * 1997-09-05 1999-03-23 Sumitomo Pharmaceut Co Ltd 免疫抑制剤
DE19831878C2 (de) * 1998-07-17 2001-05-17 Aventis Pharma Gmbh Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas

Also Published As

Publication number Publication date
JP2002538150A (ja) 2002-11-12
BR0008511A (pt) 2002-04-02
EP1183247B1 (de) 2005-05-25
DE50010403D1 (de) 2005-06-30
AU2441600A (en) 2000-09-21
ES2241574T3 (es) 2005-11-01
HK1042300A1 (en) 2002-08-09
KR20020000545A (ko) 2002-01-05
CA2364903A1 (en) 2000-09-08
DE19908533A1 (de) 2000-08-31
CN1341108A (zh) 2002-03-20
PT1183247E (pt) 2005-07-29
AU762802B2 (en) 2003-07-03
MY133195A (en) 2007-10-31
ATE296295T1 (de) 2005-06-15
ZA200106440B (en) 2002-03-06
WO2000051997A1 (de) 2000-09-08
TW593294B (en) 2004-06-21
DK1183247T3 (da) 2005-09-19
HK1042300B (zh) 2004-12-10
CN1149205C (zh) 2004-05-12
CO5180595A1 (es) 2002-07-30
EP1183247A1 (de) 2002-03-06
US6187801B1 (en) 2001-02-13

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