HK1042300B - 多環的噻唑體系和它們作為減食慾劑的用途 - Google Patents

多環的噻唑體系和它們作為減食慾劑的用途

Info

Publication number
HK1042300B
HK1042300B HK02104057.0A HK02104057A HK1042300B HK 1042300 B HK1042300 B HK 1042300B HK 02104057 A HK02104057 A HK 02104057A HK 1042300 B HK1042300 B HK 1042300B
Authority
HK
Hong Kong
Prior art keywords
anorectics
utilization
thiazole systems
polycyclic thiazole
polycyclic
Prior art date
Application number
HK02104057.0A
Other languages
English (en)
Other versions
HK1042300A1 (en
Inventor
G‧傑恩
K‧蓋森
H-J‧蘭格
M‧畢克爾
Original Assignee
阿文蒂斯藥物德國有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿文蒂斯藥物德國有限公司 filed Critical 阿文蒂斯藥物德國有限公司
Publication of HK1042300A1 publication Critical patent/HK1042300A1/xx
Publication of HK1042300B publication Critical patent/HK1042300B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84—Naphthothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK02104057.0A 1999-02-26 2002-05-31 多環的噻唑體系和它們作為減食慾劑的用途 HK1042300B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908533A DE19908533A1 (de) 1999-02-26 1999-02-26 Polycyclische Thiazol-Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen
PCT/EP2000/000927 WO2000051997A1 (de) 1999-02-26 2000-02-05 Polycyclische thiazol-systeme und ihre verwendung als anorektika

Publications (2)

Publication Number Publication Date
HK1042300A1 HK1042300A1 (en) 2002-08-09
HK1042300B true HK1042300B (zh) 2004-12-10

Family

ID=7899078

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02104057.0A HK1042300B (zh) 1999-02-26 2002-05-31 多環的噻唑體系和它們作為減食慾劑的用途

Country Status (18)

Country Link
US (1) US6187801B1 (zh)
EP (1) EP1183247B1 (zh)
JP (1) JP4728485B2 (zh)
KR (1) KR20020000545A (zh)
CN (1) CN1149205C (zh)
AT (1) ATE296295T1 (zh)
AU (1) AU762802B2 (zh)
BR (1) BR0008511A (zh)
CA (1) CA2364903A1 (zh)
CO (1) CO5180595A1 (zh)
DE (2) DE19908533A1 (zh)
DK (1) DK1183247T3 (zh)
ES (1) ES2241574T3 (zh)
HK (1) HK1042300B (zh)
PT (1) PT1183247E (zh)
TW (1) TW593294B (zh)
WO (1) WO2000051997A1 (zh)
ZA (1) ZA200106440B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
CA2400704C (en) 2000-02-26 2008-11-04 Aventis Pharma Deutschland Gmbh 8,8a-dihydro-indeno[1,2-d]thiazole derivatives with a sulphonamido or sulphono substituent in the 2 position, a method for production thereof and use thereof as a medicament
DE10142663B4 (de) * 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
KR100712171B1 (ko) * 2004-09-17 2007-05-02 김진우 폐타이어를 이용한 조립식 배관블록
JP5511786B2 (ja) * 2008-03-31 2014-06-04 ジェネンテック， インコーポレイテッド ベンゾピランおよびベンゾキセピンｐｉ３ｋ阻害剤化合物および使用方法
CA2774807C (en) 2009-09-28 2018-04-03 F. Hoffmann-La Roche Ag Benzoxepin pi3k inhibitor compounds and methods of use
WO2011036280A1 (en) 2009-09-28 2011-03-31 F. Hoffmann-La Roche Ag Benzoxazepin pi3k inhibitor compounds and methods of use
EP2688891B1 (en) 2011-03-21 2017-11-15 F. Hoffmann-La Roche AG Benzoxazepin compounds selective for pi3k p110 delta and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
MX9603998A (es) * 1994-03-11 1997-12-31 Yamanouchi Pharma Co Ltd Agonista receptor de 5-ht3, derivado de tiazol novedoso e intermediario del mismo.
JPH1179993A (ja) * 1997-09-05 1999-03-23 Sumitomo Pharmaceut Co Ltd 免疫抑制剤
DE19831878C2 (de) * 1998-07-17 2001-05-17 Aventis Pharma Gmbh Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas

Also Published As

Publication number Publication date
US6187801B1 (en) 2001-02-13
DE19908533A1 (de) 2000-08-31
JP4728485B2 (ja) 2011-07-20
EP1183247B1 (de) 2005-05-25
DK1183247T3 (da) 2005-09-19
EP1183247A1 (de) 2002-03-06
DE50010403D1 (de) 2005-06-30
TW593294B (en) 2004-06-21
PT1183247E (pt) 2005-07-29
CN1341108A (zh) 2002-03-20
BR0008511A (pt) 2002-04-02
ZA200106440B (en) 2002-03-06
AU762802B2 (en) 2003-07-03
AU2441600A (en) 2000-09-21
JP2002538150A (ja) 2002-11-12
CN1149205C (zh) 2004-05-12
HK1042300A1 (en) 2002-08-09
ATE296295T1 (de) 2005-06-15
ES2241574T3 (es) 2005-11-01
CO5180595A1 (es) 2002-07-30
CA2364903A1 (en) 2000-09-08
KR20020000545A (ko) 2002-01-05
WO2000051997A1 (de) 2000-09-08

Similar Documents

Publication Publication Date Title
AU2795000A (en) Epothilone derivatives and their use as antitumor agents
MY139302A (en) Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
MY137039A (en) Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof
MY139303A (en) Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
DE60204452D1 (de) Pyrazolo[1,5]pyridinderivate
AU2002239344A1 (en) Pyrazolopyridines
SG149067A1 (en) IMIDAZO[4,5-c]PYRIDINE COMPOUNDS AND METHODS OF ANTIVIRAL TREATMENT
ES2243579T3 (es) Derivados de pirazolopirideno.
YU56302A (sh) Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstva
HK1043117A1 (en) Polycyclic 2-amino-thiazole systems, method for the production thereof and medicament containing said compounds
TW200407282A (en) Urea- and urethane-substituted acylureas, process for their preparation and their use
HK1042300A1 (en) Polycyclic thiazole systems and their utilization as anorectics.
HK1056725A1 (en) 2-Thio-substituted imidazole derivatives and the use thereof in the pharmaceutical industry.
RS88704A (en) Acyl-3-carboxyphenylurea derivatives, method for production and use thereof
AU2002248531A1 (en) Pyrazolopyriadine derivatives
AU2002357740A1 (en) Pyrazolo-pyridine derivatives as antiherpes agents
TW200504051A (en) Novel acridine derivatives and their use as medicaments
MXPA04001855A (es) Derivados de sistemas de indan-1-ol c2-sustituidos, metodos para la produccion de los mismos y su uso como medicamentos.
IL148161A0 (en) Process for the preparation of 2-cyanopyridines
HK1042299A1 (en) Polycyclic thiazole-2-ylides amines, method for the production thereof and their utilization as medicaments.
CA2390631A1 (en) Carboxamide-substituted benzimidazole derivatives, processes for preparing them and their use as pharmaceutical compositions
MXPA04001856A (es) Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos.
MXPA03003466A (es) Derivados de piranosido.
MXPA04001849A (es) Sistemas de indan-1-ol c2-disustituidos, metodo para su produccion y su uso como medicamentos.
MXPA04001846A (es) Indan-1-onas c2-substituidas y sus derivados, metodos para su produccion y su uso como medicamentos.

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080205