DK1183247T3 - Polycycliske thiazolsystemer, fremgangsmåde til fremstilling heraf og lægemidler indeholdende disse forbindelser - Google Patents

Polycycliske thiazolsystemer, fremgangsmåde til fremstilling heraf og lægemidler indeholdende disse forbindelser

Info

Publication number
DK1183247T3
DK1183247T3 DK00902658T DK00902658T DK1183247T3 DK 1183247 T3 DK1183247 T3 DK 1183247T3 DK 00902658 T DK00902658 T DK 00902658T DK 00902658 T DK00902658 T DK 00902658T DK 1183247 T3 DK1183247 T3 DK 1183247T3
Authority
DK
Denmark
Prior art keywords
compounds
processes
preparation
drugs containing
thiazole systems
Prior art date
Application number
DK00902658T
Other languages
English (en)
Inventor
Gerhard Jaehne
Karl Geisen
Hans-Jochen Lang
Martin Bickel
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK1183247T3 publication Critical patent/DK1183247T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84Naphthothiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK00902658T 1999-02-26 2000-02-05 Polycycliske thiazolsystemer, fremgangsmåde til fremstilling heraf og lægemidler indeholdende disse forbindelser DK1183247T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19908533A DE19908533A1 (de) 1999-02-26 1999-02-26 Polycyclische Thiazol-Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen
PCT/EP2000/000927 WO2000051997A1 (de) 1999-02-26 2000-02-05 Polycyclische thiazol-systeme und ihre verwendung als anorektika

Publications (1)

Publication Number Publication Date
DK1183247T3 true DK1183247T3 (da) 2005-09-19

Family

ID=7899078

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00902658T DK1183247T3 (da) 1999-02-26 2000-02-05 Polycycliske thiazolsystemer, fremgangsmåde til fremstilling heraf og lægemidler indeholdende disse forbindelser

Country Status (18)

Country Link
US (1) US6187801B1 (da)
EP (1) EP1183247B1 (da)
JP (1) JP4728485B2 (da)
KR (1) KR20020000545A (da)
CN (1) CN1149205C (da)
AT (1) ATE296295T1 (da)
AU (1) AU762802B2 (da)
BR (1) BR0008511A (da)
CA (1) CA2364903A1 (da)
CO (1) CO5180595A1 (da)
DE (2) DE19908533A1 (da)
DK (1) DK1183247T3 (da)
ES (1) ES2241574T3 (da)
HK (1) HK1042300B (da)
PT (1) PT1183247E (da)
TW (1) TW593294B (da)
WO (1) WO2000051997A1 (da)
ZA (1) ZA200106440B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
KR100763214B1 (ko) * 2000-02-26 2007-10-08 사노피-아벤티스 도이칠란트 게엠베하 2 위치에서 설폰아미도 또는 설포노 치환체를 갖는 8,8a-디하이드로-인데노[1,2-d]티아졸 유도체, 이의 제조방법 및 이를 포함하는 약제
DE10142663B4 (de) 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
KR100712171B1 (ko) * 2004-09-17 2007-05-02 김진우 폐타이어를 이용한 조립식 배관블록
ES2480994T3 (es) * 2008-03-31 2014-07-29 Genentech, Inc. Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso
BR112012006802A2 (pt) 2009-09-28 2020-08-18 F.Hoffmann-La Roche Ag composto, composição farmacêutica, método para tratar câncer, usos de um composto, kit e invenção
ES2444779T3 (es) 2009-09-28 2014-02-26 F. Hoffmann-La Roche Ag Compuestos de benzoxazepina inhibidores de la PI3K y su utilización en el tratamiento de cáncer
RU2013143747A (ru) 2011-03-21 2015-04-27 Ф. Хоффманн-Ля Рош Аг Соединения бензоксазепина, селективные в отношении pi3k p110 дельта и способы их применения

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
CN1143364A (zh) * 1994-03-11 1997-02-19 山之内制药株式会社 5-ht3受体激动剂、新颖的噻唑衍生物及其中间体
JPH1179993A (ja) * 1997-09-05 1999-03-23 Sumitomo Pharmaceut Co Ltd 免疫抑制剤
DE19831878C2 (de) * 1998-07-17 2001-05-17 Aventis Pharma Gmbh Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908535A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Verwendung von polycyclischen Thiazol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas

Also Published As

Publication number Publication date
AU762802B2 (en) 2003-07-03
CN1341108A (zh) 2002-03-20
WO2000051997A1 (de) 2000-09-08
ES2241574T3 (es) 2005-11-01
HK1042300A1 (en) 2002-08-09
ATE296295T1 (de) 2005-06-15
KR20020000545A (ko) 2002-01-05
CA2364903A1 (en) 2000-09-08
DE50010403D1 (de) 2005-06-30
CN1149205C (zh) 2004-05-12
JP4728485B2 (ja) 2011-07-20
HK1042300B (zh) 2004-12-10
ZA200106440B (en) 2002-03-06
JP2002538150A (ja) 2002-11-12
AU2441600A (en) 2000-09-21
US6187801B1 (en) 2001-02-13
TW593294B (en) 2004-06-21
DE19908533A1 (de) 2000-08-31
PT1183247E (pt) 2005-07-29
CO5180595A1 (es) 2002-07-30
EP1183247A1 (de) 2002-03-06
BR0008511A (pt) 2002-04-02
EP1183247B1 (de) 2005-05-25

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