JP4689044B2 - ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片 - Google Patents
ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片 Download PDFInfo
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- JP4689044B2 JP4689044B2 JP2000589215A JP2000589215A JP4689044B2 JP 4689044 B2 JP4689044 B2 JP 4689044B2 JP 2000589215 A JP2000589215 A JP 2000589215A JP 2000589215 A JP2000589215 A JP 2000589215A JP 4689044 B2 JP4689044 B2 JP 4689044B2
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- amino acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1275—Streptococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11304898P | 1998-12-21 | 1998-12-21 | |
| US60/113,048 | 1998-12-21 | ||
| PCT/US1999/030390 WO2000037105A2 (en) | 1998-12-21 | 1999-12-21 | Streptococcus pneumoniae proteins and immunogenic fragments for vaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002532561A JP2002532561A (ja) | 2002-10-02 |
| JP2002532561A5 JP2002532561A5 (cg-RX-API-DMAC7.html) | 2007-02-15 |
| JP4689044B2 true JP4689044B2 (ja) | 2011-05-25 |
Family
ID=22347343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000589215A Expired - Fee Related JP4689044B2 (ja) | 1998-12-21 | 1999-12-21 | ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US6582706B1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2050464B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4689044B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE422899T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU776828B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2355364C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1109024T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69940439D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1140157T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2322306T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1140157E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2000037105A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (112)
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| US6676943B1 (en) | 1997-04-24 | 2004-01-13 | Regents Of The University Of Minnesota | Human complement C3-degrading protein from Streptococcus pneumoniae |
| US7129339B1 (en) | 1997-07-02 | 2006-10-31 | Sanofi Pasteur Limited | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| ATE347600T1 (de) | 1998-02-20 | 2006-12-15 | Id Biomedical Corp | Gruppe b-streptococcus antigene |
| NZ530277A (en) * | 1998-04-07 | 2005-08-26 | Medimmune Inc | Derivatives of pneumococcal choline binding proteins for vaccines |
| WO2000005378A2 (en) | 1998-07-22 | 2000-02-03 | Id-Lelystad Instituut Voor Dierhouderij En Diergezondheid B.V. | Streptococcus suis vaccines and diagnostic tests |
| US20030134407A1 (en) | 1998-07-27 | 2003-07-17 | Le Page Richard William Falla | Nucleic acids and proteins from Streptococcus pneumoniae |
| EP1801218A3 (en) * | 1998-07-27 | 2007-10-10 | Sanofi Pasteur Limited | Nucleic acids and proteins from streptococcus pneumoniae |
| EP1950302B1 (en) | 1998-12-23 | 2012-12-05 | ID Biomedical Corporation of Quebec | Streptococcus antigens |
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| PL205041B1 (pl) * | 1998-12-23 | 2010-03-31 | Id Biomedical Corp | Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem |
| CA2366152A1 (en) * | 1999-03-19 | 2000-09-28 | Smithkline Beecham Biologicals S.A. | Streptococcus pneumoniae vaccine |
| US6887480B1 (en) * | 1999-06-10 | 2005-05-03 | Medimmune, Inc. | Streptococcus pneumoniae proteins and vaccines |
| EP1290019A2 (en) * | 2000-06-14 | 2003-03-12 | Cytovax Biotechnologies Inc. | Use of coiled-coil structural scaffold to generate structure-specific peptides |
| US7074415B2 (en) * | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
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| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| WO2002061070A2 (en) | 2001-02-02 | 2002-08-08 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Environmentally regulated genes, involved in the virulence of streptococcus suis |
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| US8229903B2 (en) * | 2002-12-19 | 2012-07-24 | International Business Machines Corporation | Suggesting data interpretations and patterns for updating policy documents |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| EP1754717A1 (en) | 2005-08-19 | 2007-02-21 | Université de Lausanne | Antigenic peptides and their use |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
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| AU2008287286B2 (en) | 2007-04-13 | 2013-10-10 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
| JP2010525035A (ja) | 2007-05-02 | 2010-07-22 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
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| WO2025133971A1 (en) | 2023-12-23 | 2025-06-26 | Pfizer Inc. | Improved methods for producing bacterial capsular saccharide glycoconjugates |
| WO2025186705A2 (en) | 2024-03-06 | 2025-09-12 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| TW202602467A (zh) | 2024-03-11 | 2026-01-16 | 美商輝瑞股份有限公司 | 包含經共軛之大腸桿菌糖的免疫原性組成物及其用途 |
| WO2025219908A2 (en) | 2024-04-19 | 2025-10-23 | Pfizer Inc. | Media and fermentation methods for polysaccharide production in bacterial cell culture |
| WO2025219904A1 (en) | 2024-04-19 | 2025-10-23 | Pfizer Inc. | Improved methods for producing glycoconjugates by reductive amination in aprotic solvent |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100664A (en) * | 1985-09-20 | 1992-03-31 | Cetus Corporation | Human IL-2 as a vaccine adjuvant |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6042838A (en) * | 1991-02-15 | 2000-03-28 | Uab Research Foundation | immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA) |
| US5928900A (en) | 1993-09-01 | 1999-07-27 | The Rockefeller University | Bacterial exported proteins and acellular vaccines based thereon |
| WO1997041151A2 (en) | 1996-05-01 | 1997-11-06 | The Rockefeller University | Choline binding proteins for anti-pneumococcal vaccines |
| EP0912193A4 (en) | 1996-06-21 | 2000-11-02 | Univ Virginia Commonwealth | Vaccine for the prevention of streptococcal endocarditis |
| ATE348887T1 (de) | 1996-10-31 | 2007-01-15 | Human Genome Sciences Inc | Streptococcus pneumoniae antigene und impfstoffe |
| US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| EP1017828A1 (en) * | 1997-09-24 | 2000-07-12 | Regents Of The University Of Minnesota | HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE) |
| WO2000006737A2 (en) * | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| EP1115875A1 (en) | 1998-09-24 | 2001-07-18 | Regents Of The University Of Minnesota | Human complement c3-degrading polypeptide from streptococcus pneumoniae |
| PL205041B1 (pl) | 1998-12-23 | 2010-03-31 | Id Biomedical Corp | Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem |
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1999
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- 1999-12-21 EP EP09001206.3A patent/EP2050464B1/en not_active Expired - Lifetime
- 1999-12-21 AT AT99967460T patent/ATE422899T1/de active
- 1999-12-21 AU AU23731/00A patent/AU776828B2/en not_active Ceased
- 1999-12-21 US US09/468,656 patent/US6582706B1/en not_active Expired - Lifetime
- 1999-12-21 ES ES99967460T patent/ES2322306T3/es not_active Expired - Lifetime
- 1999-12-21 WO PCT/US1999/030390 patent/WO2000037105A2/en not_active Ceased
- 1999-12-21 DE DE69940439T patent/DE69940439D1/de not_active Expired - Lifetime
- 1999-12-21 PT PT99967460T patent/PT1140157E/pt unknown
- 1999-12-21 JP JP2000589215A patent/JP4689044B2/ja not_active Expired - Fee Related
- 1999-12-21 EP EP99967460A patent/EP1140157B1/en not_active Revoked
- 1999-12-21 DK DK99967460T patent/DK1140157T3/da active
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- 2003-03-13 US US10/387,783 patent/US20040005331A1/en not_active Abandoned
- 2003-04-14 US US10/412,862 patent/US20040052781A1/en not_active Abandoned
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| Publication number | Publication date |
|---|---|
| US6582706B1 (en) | 2003-06-24 |
| DK1140157T3 (da) | 2009-06-08 |
| ES2322306T3 (es) | 2009-06-18 |
| US20040005331A1 (en) | 2004-01-08 |
| CA2355364C (en) | 2014-03-18 |
| AU776828B2 (en) | 2004-09-23 |
| US20040001836A1 (en) | 2004-01-01 |
| US20070065458A1 (en) | 2007-03-22 |
| PT1140157E (pt) | 2009-05-06 |
| CA2355364A1 (en) | 2000-06-29 |
| CY1109024T1 (el) | 2014-07-02 |
| EP2050464A3 (en) | 2012-04-25 |
| US20040052781A1 (en) | 2004-03-18 |
| EP1140157A2 (en) | 2001-10-10 |
| ATE422899T1 (de) | 2009-03-15 |
| WO2000037105A2 (en) | 2000-06-29 |
| JP2002532561A (ja) | 2002-10-02 |
| AU2373100A (en) | 2000-07-12 |
| EP2050464A2 (en) | 2009-04-22 |
| EP1140157B1 (en) | 2009-02-18 |
| DE69940439D1 (de) | 2009-04-02 |
| US7122194B2 (en) | 2006-10-17 |
| WO2000037105A3 (en) | 2000-11-09 |
| EP2050464B1 (en) | 2019-08-07 |
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