JP4680190B2 - 注射装置 - Google Patents

注射装置 Download PDF

Info

Publication number
JP4680190B2
JP4680190B2 JP2006521759A JP2006521759A JP4680190B2 JP 4680190 B2 JP4680190 B2 JP 4680190B2 JP 2006521759 A JP2006521759 A JP 2006521759A JP 2006521759 A JP2006521759 A JP 2006521759A JP 4680190 B2 JP4680190 B2 JP 4680190B2
Authority
JP
Japan
Prior art keywords
housing
shield
driver
injector
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2006521759A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007500530A (ja
JP2007500530A5 (enExample
Inventor
ラビ，ギラッド
ツァルス，イズライル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sid Technologies LLC
Original Assignee
Sid Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sid Technologies LLC filed Critical Sid Technologies LLC
Publication of JP2007500530A publication Critical patent/JP2007500530A/ja
Publication of JP2007500530A5 publication Critical patent/JP2007500530A5/ja
Application granted granted Critical
Publication of JP4680190B2 publication Critical patent/JP4680190B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2418—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for damping shocks on ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247—Means to impede repositioning of protection sleeve from needle covering to needle uncovering position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3271—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel with guiding tracks for controlled sliding of needle protective sleeve from needle exposing to needle covering position

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2006521759A 2003-07-31 2004-07-28 注射装置 Expired - Lifetime JP4680190B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49119603P 2003-07-31 2003-07-31
US51893603P 2003-11-12 2003-11-12
PCT/IB2004/051318 WO2005009515A1 (en) 2003-07-31 2004-07-28 Injecting apparatus

Publications (3)

Publication Number Publication Date
JP2007500530A JP2007500530A (ja) 2007-01-18
JP2007500530A5 JP2007500530A5 (enExample) 2007-09-13
JP4680190B2 true JP4680190B2 (ja) 2011-05-11

Family

ID=34107966

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006521759A Expired - Lifetime JP4680190B2 (ja) 2003-07-31 2004-07-28 注射装置

Country Status (5)

Country Link
US (2) US20050027255A1 (enExample)
EP (1) EP1654020B1 (enExample)
JP (1) JP4680190B2 (enExample)
DE (1) DE602004026197D1 (enExample)
WO (1) WO2005009515A1 (enExample)

Families Citing this family (289)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE409057T1 (de) 2002-02-11 2008-10-15 Antares Pharma Inc Intradermales injektionsgerät
US9486581B2 (en) * 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
IL157981A (en) 2003-09-17 2014-01-30 Elcam Medical Agricultural Cooperative Ass Ltd Auto injector
GB2410188B (en) * 2004-01-23 2006-01-25 Medical House Plc Injection device
DE102004019325A1 (de) * 2004-04-21 2005-11-24 Tecpharma Licensing Ag Verabreichungsgerät mit Primingfunktion
GB2414399B (en) * 2004-05-28 2008-12-31 Cilag Ag Int Injection device
GB2414400B (en) * 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414402B (en) * 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414401B (en) 2004-05-28 2009-06-17 Cilag Ag Int Injection device
GB2414403B (en) * 2004-05-28 2009-01-07 Cilag Ag Int Injection device
GB2414404B (en) 2004-05-28 2009-06-03 Cilag Ag Int Injection device
GB2414406B (en) 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414775B (en) * 2004-05-28 2008-05-21 Cilag Ag Int Releasable coupling and injection device
GB2414409B (en) * 2004-05-28 2009-11-18 Cilag Ag Int Injection device
GB2414405B (en) * 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
CA2791286C (en) * 2004-11-22 2015-09-01 Intelliject, Inc. Devices, systems, and methods for medicament delivery
CA2595730C (en) 2005-01-24 2014-10-07 Antares Pharma, Inc. Prefilled needle assisted syringe jet injector
US8226610B2 (en) 2005-02-01 2012-07-24 Intelliject, Inc. Medical injector with compliance tracking and monitoring
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
PL2058020T3 (pl) 2005-02-01 2013-03-29 Kaleo Inc Urządzenie do podawania leków
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8062252B2 (en) * 2005-02-18 2011-11-22 Becton, Dickinson And Company Safety shield system for a syringe
GB2424837B (en) * 2005-04-06 2010-10-06 Cilag Ag Int Injection device
GB2427826B (en) 2005-04-06 2010-08-25 Cilag Ag Int Injection device comprising a locking mechanism associated with integrally formed biasing means
GB2424835B (en) * 2005-04-06 2010-06-09 Cilag Ag Int Injection device (modified trigger)
GB2424838B (en) * 2005-04-06 2011-02-23 Cilag Ag Int Injection device (adaptable drive)
GB2424836B (en) * 2005-04-06 2010-09-22 Cilag Ag Int Injection device (bayonet cap removal)
GB2425062B (en) * 2005-04-06 2010-07-21 Cilag Ag Int Injection device
ES2677022T3 (es) * 2005-04-20 2018-07-27 Becton Dickinson France Conjunto de inyección y dispositivo de asistencia de inyección
FR2884722A1 (fr) * 2005-04-20 2006-10-27 Becton Dickinson France Soc Pa Ensemble d'injection et dispositif d'assistance
FR2884721A1 (fr) * 2005-04-20 2006-10-27 Becton Dickinson France Soc Pa Ensemble d'injection et dispositif d'assistance a l'injection
US7609567B2 (en) * 2005-06-24 2009-10-27 Metaram, Inc. System and method for simulating an aspect of a memory circuit
EP1919363B1 (en) * 2005-07-14 2010-10-20 Bayer HealthCare, LLC Lancing device for one skin puncture
DK1759729T3 (da) * 2005-08-30 2010-04-19 Cilag Gmbh Int Nåleindretning til en forfyldt sprøjte
US20110098656A1 (en) * 2005-09-27 2011-04-28 Burnell Rosie L Auto-injection device with needle protecting cap having outer and inner sleeves
GB2433032A (en) 2005-12-08 2007-06-13 Owen Mumford Ltd Syringe with dose adjustment means
US20070173770A1 (en) 2006-01-23 2007-07-26 The Medical House Plc Injection device
GB0601309D0 (en) * 2006-01-23 2006-03-01 Medical House The Plc Injection device
US8033978B2 (en) * 2006-04-05 2011-10-11 Mick Radio-Nuclear Instruments, Inc. Radio-nuclear material delivery system
FR2899482A1 (fr) * 2006-04-11 2007-10-12 Becton Dickinson France Soc Pa Dispositif d'injection automatique
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
WO2007131025A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injector with adjustable dosing
KR100770829B1 (ko) 2006-05-08 2007-10-26 삼성전자주식회사 자기 거치 기능을 구비한 슬라이딩 타입 휴대 단말기, 그의 슬라이딩 가이드 모듈 및 슬라이딩 가이드 모듈의 장착 장치
GB2437922B (en) 2006-05-10 2010-12-08 Owen Mumford Ltd Injection device comprising a window and a shutter element
GB2438591B (en) * 2006-06-01 2011-07-13 Cilag Gmbh Int Injection device
GB2438593B (en) 2006-06-01 2011-03-30 Cilag Gmbh Int Injection device (cap removal feature)
GB2438590B (en) 2006-06-01 2011-02-09 Cilag Gmbh Int Injection device
USD579542S1 (en) * 2006-06-09 2008-10-28 Baxa Corporation Medical liquid administration device
TWI542374B (zh) * 2006-06-30 2016-07-21 艾伯維生物技術有限責任公司 自動注射裝置
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
JP4131001B2 (ja) * 2006-07-28 2008-08-13 大成化工株式会社 定量吐出装置
SG140491A1 (en) * 2006-08-29 2008-03-28 Nanyang Polytechnic An injection device
WO2008047372A2 (en) 2006-10-19 2008-04-24 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device
ES2365931T3 (es) * 2006-12-13 2011-10-13 Shl Group Ab Inyector automático.
GB0625169D0 (en) 2006-12-18 2007-01-24 Medical House Plc The Improved autoinjector
DE102007002096A1 (de) * 2007-01-09 2008-07-10 B. Braun Melsungen Ag Vorrichtung zur Injektion von Flüssigkeiten
GB0704351D0 (en) * 2007-03-07 2007-04-11 Medical House Plc The Improved autoinjector
US20080228147A1 (en) * 2007-03-15 2008-09-18 Bristol-Myers Squibb Company Injector for use with pre-filled syringes and method of assembly
US9539042B2 (en) * 2007-03-30 2017-01-10 Orthovita, Inc. Syringe for the delivery of viscous compositions
JP5311685B2 (ja) 2007-07-19 2013-10-09 エス・ホー・エル・グループ・アクチボラゲット 薬剤を送達するための装置
GB2452030A (en) * 2007-08-10 2009-02-25 Owen Mumford Ltd Injection devices
WO2009023893A1 (en) * 2007-08-21 2009-02-26 Safety Midical Products Limited Lockable shield assembly for a syringe
EP2195052B1 (en) 2007-10-02 2019-09-04 Medimop Medical Projects Ltd. External drug pump
JP5243548B2 (ja) 2007-10-25 2013-07-24 プロテウス デジタル ヘルス， インコーポレイテッド 情報システムのための流体伝達ポート
DE602008006458D1 (de) † 2007-11-12 2011-06-01 Bang & Olufsen Medicom As Automatischer injektor mit automatischem nadeleinzug
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
ES2589322T3 (es) * 2008-02-11 2016-11-11 Safety Syringes, Inc. Jeringa con protector de seguridad de aguja y clip para evitar la liberación del protector durante un proceso de reconstitución
EP3636301A1 (en) 2008-03-10 2020-04-15 Antares Pharma, Inc. Injector safety device
US7749191B2 (en) * 2008-03-20 2010-07-06 Beutlich Lp, Pharmaceuticals Device and method for drug delivery
GB0806814D0 (en) * 2008-04-15 2008-05-14 Medical House Plc The Improved autoinjector
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
AU2009249027C1 (en) 2008-05-20 2015-01-22 Avant Medical Corp. Autoinjector system
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
GB2460398A (en) 2008-05-20 2009-12-02 Owen Mumford Ltd Auto-injector having a magnetic injection indicator and a needle sheath retainer
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
AU2009256717B9 (en) 2008-06-10 2013-05-23 Shl Medical Ag Injection needle assembly
GB2461086B (en) * 2008-06-19 2012-12-05 Cilag Gmbh Int Injection device
GB2461084B (en) * 2008-06-19 2012-09-26 Cilag Gmbh Int Fluid transfer assembly
GB2461085B (en) 2008-06-19 2012-08-29 Cilag Gmbh Int Injection device
GB2461087B (en) * 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461088B (en) 2008-06-19 2012-09-26 Cilag Gmbh Int Injection device
GB2461089B (en) * 2008-06-19 2012-09-19 Cilag Gmbh Int Injection device
CA2732812C (en) 2008-08-05 2017-10-31 Antares Pharma, Inc. Multiple dosage injector
DE102008037310B4 (de) 2008-08-11 2023-11-16 Ypsomed Ag Automatische Injektionsvorrichtung für die Verabreichung einer festen Dosis
GB2463071A (en) * 2008-09-02 2010-03-03 Owen Mumford Ltd Auto-injector syringe with safety shield
US12097357B2 (en) 2008-09-15 2024-09-24 West Pharma. Services IL, Ltd. Stabilized pen injector
ES2824839T3 (es) * 2008-09-18 2021-05-13 Becton Dickinson Co Inyector médico con activación de manguito deslizante
ES2988196T3 (es) 2009-03-20 2024-11-19 Antares Pharma Inc Sistema de inyección de agentes peligrosos
GB2469672B (en) 2009-04-23 2013-09-25 Medical House Ltd Improved autoinjector
RU2524487C2 (ru) 2009-04-29 2014-07-27 Эббви Байотекнолоджи Лтд Автоматическое инъекционное устройство
EP2424611A4 (en) 2009-05-01 2012-10-24 Nanbu Plastics Co Ltd DEVICE FOR TRANSDERMAL ADMINISTRATIONS
GB0907534D0 (en) * 2009-05-01 2009-06-10 Owen Mumford Ltd Injection devices
PT2300078E (pt) 2009-05-07 2016-06-23 Medical Injection Devices Inc Dispositivo dispensador de medicamentos
US9265892B2 (en) 2009-05-07 2016-02-23 Eric Segal Medicament dispensing device
FI2255842T4 (fi) 2009-05-26 2023-08-31 Neulansuojusyksikkö
DK2954914T3 (en) 2009-05-29 2019-03-11 Tecpharma Licensing Ag Injection device, especially auto-injector with plug protection and / or overload protection for a product container
US9526846B2 (en) 2009-08-19 2016-12-27 Safety Syringes, Inc. Patient-contact activated needle stick safety device
JP5701889B2 (ja) * 2009-10-08 2015-04-15 エス・ホー・エル・グループ・アクチボラゲットＳｈｌ Ｇｒｏｕｐ Ａｂ 薬物供給装置
CA2777424C (en) 2009-10-16 2017-09-05 Janssen Biotech, Inc. Palm activated drug delivery device
US9233213B2 (en) 2009-10-16 2016-01-12 Janssen Biotech, Inc. Palm activated drug delivery device
US20110105990A1 (en) * 2009-11-04 2011-05-05 Silvestrini Thomas A Zonal drug delivery device and method
WO2011075524A1 (en) * 2009-12-15 2011-06-23 Abbott Biotechnology Ltd Improved firing button for automatic injection device
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
JP5598903B2 (ja) * 2010-01-29 2014-10-01 富士電機エフテック株式会社 薬液用電動注射器
SG10201503428RA (en) 2010-02-01 2015-06-29 Proteus Digital Health Inc Data Gathering System
WO2011094606A2 (en) 2010-02-01 2011-08-04 Proteus Biomedical, Inc. Data gathering system
CA2790193A1 (en) 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Auto-injector
DK2536454T3 (en) * 2010-02-18 2016-11-28 Sanofi Aventis Deutschland Auto-injector with delay mechanism
EP2361648A1 (en) * 2010-02-18 2011-08-31 Sanofi-Aventis Deutschland GmbH Remover for a protective needle shield
IT1398501B1 (it) * 2010-03-10 2013-03-01 Menarini Int Operations Lu Sa Dispositivo autoiniettore di due dosi di farmaco
SI3184136T1 (sl) 2010-03-25 2021-11-30 New Injection Systems Ltd Injektor
RU2531118C2 (ru) * 2010-03-31 2014-10-20 Схл Груп Аб Устройство введения лекарственного средства, содержащее сигнальное средство обратной связи
CA2796186C (en) 2010-04-21 2019-04-09 Abbott Biotechnology Ltd. Wearable automatic injection device for controlled delivery of therapeutic agents
DE102010018529A1 (de) * 2010-04-27 2011-10-27 Lts Lohmann Therapie-Systeme Ag Einmalinjektor mit biegeelastischem Kolbenbetätigungsstempel
US20110306933A1 (en) * 2010-06-11 2011-12-15 Ilija Djordjevic Safety cannula with automatic retractable needle
EP2399627A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2399635A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
JP6165055B2 (ja) * 2010-06-28 2017-07-19 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 自動注射器
EP2399632A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto injector with a single compression spring and a laterraly trigger button
US9427531B2 (en) 2010-06-28 2016-08-30 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2399629A1 (en) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2399634A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Needle safety arrangement and method for operating it
EP2399630A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2399628A1 (en) * 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injector
CA2803686A1 (en) * 2010-07-02 2012-01-05 Sanofi-Aventis Deutschland Gmbh Needle shield for a safety device, safety device and injection device
WO2012022810A2 (en) 2010-08-19 2012-02-23 Novo Nordisk A/S Medical injection device
CN103167887B (zh) 2010-08-27 2015-07-15 诺沃—诺迪斯克有限公司 医用注射装置
EP2438939A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Arrangement for coupling a plunger to either a syringe or a stopper
EP2438947A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2438952A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Finger guard for an injection device
EP2438944A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto-injector
WO2012071400A2 (en) 2010-11-22 2012-05-31 B. Braun Melsungen Ag Hinged shield assemblies and related methods
USRE48593E1 (en) 2010-12-21 2021-06-15 Sanofi-Aventis Deutschland Gmbh Auto-injector
EP2468336A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468335A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468333A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468331A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2468330A1 (en) 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
GB2486681B (en) 2010-12-22 2017-02-01 Owen Mumford Ltd Autoinjectors
AU2012209223B2 (en) 2011-01-24 2015-11-05 Abbvie Biotechnology Ltd Automatic injection devices having overmolded gripping surfaces
ES2710905T3 (es) 2011-01-24 2019-04-29 E3D Agricultural Coop Association Ltd Inyector
JP5968914B2 (ja) 2011-01-24 2016-08-10 アッヴィ バイオテクノロジー リミテッド シリンジおよび自動注入デバイスからの針シールドの取り外し
US9173999B2 (en) 2011-01-26 2015-11-03 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
EP2489387A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489382A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489383A1 (en) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489388A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489386A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489380A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Injection device
EP2489390A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Detent mechanism
EP2489385A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489381A1 (en) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489384A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2489389A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Detent mechanism
GB2488578B (en) 2011-03-02 2017-05-24 Owen Mumford Ltd Injection device
GB2488579A (en) 2011-03-02 2012-09-05 Owen Mumford Ltd Autoinjector with "injection complete" indicator
JP2014515658A (ja) 2011-03-29 2014-07-03 アッヴィ・インコーポレイテッド 自動注射装置における改善されたシュラウド展開
US10092706B2 (en) 2011-04-20 2018-10-09 Amgen Inc. Autoinjector apparatus
BR112013028747A2 (pt) * 2011-05-13 2017-01-31 Sanofi-Aventis Deustchland Gmbh dispositivo de distribuição de fármaco compreendendo elemento de trava de segurança
US8806952B1 (en) * 2011-07-14 2014-08-19 David Ewing Glass Measuring sports net tension
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
CH705345A2 (de) * 2011-08-04 2013-02-15 Tecpharma Licensing Ag Injektionsvorrichtung mit Nadelschutzeinrichtung.
ITFI20110194A1 (it) 2011-09-08 2013-03-09 Menarini Int Operations Lu Sa Dispositivo autoiniettore di dosi di farmaco
CA2849806A1 (en) 2011-09-22 2013-03-28 Abbvie Inc. Automatic injection device
EP2583706A1 (en) * 2011-10-21 2013-04-24 Sanofi-Aventis Deutschland GmbH Auto-injector
EP2583705A1 (en) * 2011-10-21 2013-04-24 Sanofi-Aventis Deutschland GmbH Indicator arrangement for an auto-injector
MX366271B (es) 2011-11-07 2019-07-04 Safety Syringes Inc Guarda de aguja para liberacion de activador de contacto.
EP2601992A1 (en) 2011-12-08 2013-06-12 Sanofi-Aventis Deutschland GmbH Syringe carrier
EP2606924A1 (en) 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector having a retracting syringe carrier
EP4327849A3 (en) 2012-03-06 2024-04-24 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
WO2013146011A1 (ja) * 2012-03-30 2013-10-03 テルモ株式会社 液体投与具
CN104487114A (zh) 2012-04-06 2015-04-01 安塔雷斯药品公司 针头辅助喷射注射给予睾酮组合物
USD808010S1 (en) 2012-04-20 2018-01-16 Amgen Inc. Injection device
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
EP2662104A1 (en) * 2012-05-07 2013-11-13 Sanofi-Aventis Deutschland GmbH Detent mechanism for a medicament delivery device
WO2013169804A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
EP2698179A1 (en) * 2012-08-14 2014-02-19 Sanofi-Aventis Deutschland GmbH Injection device
CA2991909C (en) * 2012-10-12 2020-12-29 Eli Lilly And Company Process and device for delivery of fluid by chemical reaction
EP2727617A1 (en) 2012-11-06 2014-05-07 Sanofi-Aventis Deutschland GmbH Autoinjector
BR112015010607A2 (pt) 2012-11-09 2017-12-05 Iinjec Tech Inc injetor de entrega de fluido, montagem de agulha retrátil e método para injetar pelo menos uma dose de uma medicação fluida transcutaneamente no corpo.
US10471209B2 (en) 2012-11-23 2019-11-12 New Injection Systems Ltd. Auto-injector assembly
EP2938376A4 (en) 2012-12-27 2017-01-25 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
WO2014115241A1 (ja) * 2013-01-22 2014-07-31 テルモ株式会社 液体投与具
HUE066268T2 (hu) 2013-02-11 2024-07-28 Antares Pharma Inc Csökkentett kioldóerõt igénylõ tûs befecskendezõ eszköz
ES2742046T3 (es) 2013-03-11 2020-02-12 Antares Pharma Inc Inyector de dosis con sistema de piñón
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
EP2777684A1 (en) 2013-03-14 2014-09-17 Sanofi-Aventis Deutschland GmbH Medicament container carrier and adapter
EP2968775B1 (en) 2013-03-15 2019-12-18 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
WO2014144096A1 (en) 2013-03-15 2014-09-18 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
UA127696C2 (uk) * 2013-03-15 2023-12-06 Янссен Байотек, Інк. Спосіб ін'єкції медичного препарату з пристрою для доставки медичного препарату такого типу
EP3590568A1 (de) 2013-03-22 2020-01-08 TecPharma Licensing AG Substanzabgabevorrichtung mit signalvorrichtung
GB2517896B (en) 2013-06-11 2015-07-08 Cilag Gmbh Int Injection device
GB2515032A (en) 2013-06-11 2014-12-17 Cilag Gmbh Int Guide for an injection device
GB2515039B (en) 2013-06-11 2015-05-27 Cilag Gmbh Int Injection Device
GB2515038A (en) * 2013-06-11 2014-12-17 Cilag Gmbh Int Injection device
EP2823841A1 (en) 2013-07-09 2015-01-14 Sanofi-Aventis Deutschland GmbH Autoinjector
CA2938787C (en) 2014-02-10 2022-08-09 Menachem Zucker Semi disposable auto injector
EP2923714A1 (en) 2014-03-28 2015-09-30 Sanofi-Aventis Deutschland GmbH Autoinjector triggered by skin contact
EP3125975B1 (en) 2014-04-04 2021-06-09 Novo Nordisk A/S Autoinjector having needle shield triggering
WO2015169608A1 (en) 2014-05-06 2015-11-12 Carebay Europe Ltd Medicament delivery device with rotator retaining the plunger rod
JP6553656B2 (ja) * 2014-06-27 2019-07-31 ノボ・ノルデイスク・エー／エス 針シールド拘束部を有した注射装置
EP3160546A1 (en) * 2014-06-27 2017-05-03 Novo Nordisk A/S Autoinjector having needle shield triggering
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US20160078189A1 (en) * 2014-09-16 2016-03-17 Scott Laboratories, Inc. Sedation system and method providing enhanced safety
US10799634B2 (en) 2014-11-12 2020-10-13 Novo Nordisk A/S Method of manufacturing one of a range of autoinjectors
US9415176B1 (en) 2015-01-22 2016-08-16 West Pharmaceutical Services, Inc. Autoinjector having an end-of-dose visual indicator
EP3261690B1 (en) * 2015-02-27 2021-12-15 Amgen Inc. Drug delivery device having a needle guard mechanism with a tunable threshold of resistance to needle guard movement
US10029049B2 (en) 2015-03-19 2018-07-24 B. Braun Melsungen Ag Hinged shield assemblies and related methods
EP3274021B1 (en) 2015-03-24 2024-02-14 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
TW201709940A (zh) 2015-06-03 2017-03-16 賽諾菲阿凡提斯德意志有限公司 聲響指示器（一）
TW201700118A (zh) 2015-06-03 2017-01-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（三）
TW201707737A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 藥物輸送裝置（一）
TW201700117A (zh) 2015-06-03 2017-01-01 賽諾菲阿凡提斯德意志有限公司 用於自動注射器的注射筒托架和組裝方法
TW201705994A (zh) 2015-06-03 2017-02-16 賽諾菲阿凡提斯德意志有限公司 自動注射器及組裝方法
TW201709941A (zh) 2015-06-03 2017-03-16 賽諾菲阿凡提斯德意志有限公司 聲響指示器（二）
TW201707741A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 針頭護罩之抓握器、蓋子、自動注射器及製造抓握器之方法
TW201707738A (zh) 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 注射器支架及自動注射器（二）
EP4166170A1 (en) 2015-06-30 2023-04-19 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
EP4591906A3 (en) 2015-08-27 2025-09-17 E3D Agricultural Cooperative Association Ltd. Reusable automatic injection device
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
CN113648488B (zh) 2015-10-09 2024-03-29 西医药服务以色列分公司 至预填充的流体储存器的弯曲流体路径附加装置
JP6961598B2 (ja) * 2015-12-30 2021-11-05 イノビオ ファーマシューティカルズ，インコーポレイティド ロックアウトシステムを備える取り外し可能な針アレイを備えたエレクトロポレーション装置
US11260176B2 (en) 2015-12-30 2022-03-01 Novo Nordisk A/S Autoinjector having needle shield triggering
WO2017127215A1 (en) 2016-01-21 2017-07-27 Medimop Medical Projects Ltd. Needle insertion and retraction mechanism
US11311674B2 (en) 2016-01-21 2022-04-26 West Pharma. Services IL, Ltd. Medicament delivery device comprising a visual indicator
CN109219456B (zh) 2016-01-21 2020-05-15 西医药服务以色列有限公司 自动注射器中的力牵制
US20170246395A1 (en) * 2016-02-29 2017-08-31 Shl Group Ab Delivery Device
US11065390B2 (en) * 2016-02-29 2021-07-20 Shl Medical Ag Automatic delivery device with end of injection indication device
WO2017161076A1 (en) 2016-03-16 2017-09-21 Medimop Medical Projects Ltd. Staged telescopic screw assembly having different visual indicators
WO2017158366A2 (en) * 2016-03-16 2017-09-21 Oxular Limited Ophthalmic delivery device and ophthalmic drug compositions
EP4309708A3 (en) 2016-05-06 2024-04-17 SHL Medical AG Drive assembly for a medicament delivery device
EP3490643B1 (en) 2016-08-01 2021-10-27 West Pharma. Services Il, Ltd. Anti-rotation cartridge pin
WO2018026385A1 (en) 2016-08-01 2018-02-08 Medimop Medical Projects Ltd. Partial door closure prevention spring
JP6646183B2 (ja) * 2016-10-10 2020-02-14 ウェスト ファーマ サービシーズ イスラエル リミテッド 針挿入および退避機構
US20180140783A1 (en) * 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device
CA3046228A1 (en) 2016-12-23 2018-06-28 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
WO2018125629A1 (en) 2016-12-27 2018-07-05 Action Medical Technologies, Llc Apparatuses and method for injecting medicaments
US10332623B2 (en) 2017-01-17 2019-06-25 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
EP3582832B1 (en) 2017-02-17 2025-07-02 Eli Lilly and Company Processes and devices for delivery of fluid by chemical reaction
WO2018222521A1 (en) 2017-05-30 2018-12-06 West Pharma. Services IL, Ltd. Modular drive train for wearable injector
US11213631B2 (en) 2017-06-13 2022-01-04 Difinity Solutions Inc. Protected needle assembly for a hypodermic needle
CN111050826B (zh) 2017-09-08 2022-05-31 伊莱利利公司 用于控制药物递送装置内的气体生成的系统
EP3703796A1 (en) 2017-11-03 2020-09-09 Sanofi Plunger and drug delivery device
CN111587132B (zh) * 2017-11-03 2022-10-04 赛诺菲 药物递送装置
EP3703789B1 (en) * 2017-11-03 2023-11-08 Sanofi Subassembly for a drug delivery device and drug delivery device
WO2020014292A1 (en) 2018-07-10 2020-01-16 Action Medical Technologies, Llc Apparatuses and method for injecting medicaments
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
CN118217484A (zh) * 2018-08-17 2024-06-21 安进公司 用于药物递送装置的启动机构
CN108939215A (zh) * 2018-08-31 2018-12-07 浙江康德莱医疗器械股份有限公司 一种安全注射器
ES3048295T3 (en) 2018-12-19 2025-12-09 Lilly Co Eli Devices for delivery of therapeutic fluids
CN113164681B (zh) 2018-12-19 2024-12-06 伊莱利利公司 用于递送治疗性流体的装置和过程
US12478739B2 (en) 2018-12-29 2025-11-25 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
USD893712S1 (en) 2019-02-15 2020-08-18 Action Medical Technologies, Llc Grip for autoinjectors
US11759570B2 (en) 2019-02-25 2023-09-19 Difinity Solutions Inc. Medicament injector and interchangeable cartridges therefor
EP3930790A1 (en) 2019-02-26 2022-01-05 Becton Dickinson France Auto-injector with audio indicator
EP4009936A4 (en) 2019-08-09 2023-08-09 Kaleo, Inc. DEVICES AND METHODS FOR DELIVERING SUBSTANCES IN A PRE-FILLED SYRINGE
AU2020357201B2 (en) 2019-09-30 2025-11-27 Amgen Inc. Drug delivery device
CN118161706A (zh) 2019-09-30 2024-06-11 美国安进公司 药物递送装置
CN114423476B (zh) * 2019-10-23 2024-11-12 贝克顿迪金森法国公司 具有给药结束指示器的注射装置
US12458780B2 (en) * 2019-12-18 2025-11-04 Becton, Dickinson And Company Inhibiting fluid leakage and splatter in catheter devices and systems
CN114828923B (zh) * 2019-12-18 2024-07-09 诺和诺德股份有限公司 用于递送预定多个预定剂量体积的注射装置
US12502481B2 (en) 2020-02-25 2025-12-23 Difinity Solutions Inc. Medicament injector and interchangeable cartridges therefor
EP4126128B1 (en) 2020-03-25 2025-11-19 Action Medical Technologies, LLC Apparatuses and methods for injecting medicaments
CN111558109B (zh) * 2020-04-30 2022-02-22 宁波睿爱产品设计有限公司 一种具有注射提示响声的两段式自动注射器
US11759576B2 (en) 2020-06-05 2023-09-19 Action Medical Technologies, Llc Parenteral injection apparatus
US12268847B1 (en) 2021-02-10 2025-04-08 Kaleo, Inc. Devices and methods for delivery of substances within a medicament container
CN112972835B (zh) * 2021-02-25 2022-08-23 中国人民解放军陆军军医大学第一附属医院 一种用于创伤患者的肌肉注射定位装置
US11369789B2 (en) 2021-04-05 2022-06-28 Ishaan Jain Transdermal drug delivery system
EP4173656A1 (en) 2021-10-27 2023-05-03 medmix Switzerland AG Needle guard, drug delivery device and method for manufacturing
EP4651923A1 (en) * 2023-01-17 2025-11-26 SHL Medical AG Medicament delivery device and medicament delivery assembly
WO2025188598A1 (en) * 2024-03-04 2025-09-12 Genzyme Corporation Injector device
US20250276131A1 (en) 2024-03-04 2025-09-04 Genzyme Corporation Medicament delivery device
US12274874B1 (en) 2024-03-04 2025-04-15 Genzyme Corporation Injector device
US12274873B1 (en) 2024-03-04 2025-04-15 Genzyme Corporation Medicament delivery device
US12268858B1 (en) 2024-03-04 2025-04-08 Genzyme Corporation Injector device
US20250303068A1 (en) 2024-03-28 2025-10-02 Difinity Solutions Inc. Modular medicament injector and applicator and interchangeable pod therefor

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2398544A (en) * 1945-01-06 1946-04-16 Marshall L Lockhart Hypodermic injector
BE488980A (enExample) 1948-05-15
FR1078911A (fr) * 1949-08-17 1954-11-24 Seringue hypodermique automatique et son ampoule
US2701566A (en) * 1950-02-07 1955-02-08 Becton Dickinson Co Injection apparatus
US2876770A (en) * 1955-10-10 1959-03-10 Raymond A White Shielded hypodermic syringe
NL106573C (enExample) * 1957-05-31
CH400462A (de) * 1961-10-07 1965-10-15 Penicillin Ges Dauelsberg & Co Injektionsspritze
US3542023A (en) * 1968-03-06 1970-11-24 Min I Mix Corp Minimix
DE1957833A1 (de) * 1968-11-21 1970-07-02 Maurice Steiner Injektionsspritze,insbesondere von dem Patienten selbst gehandhabte Injektionsspritze
BE755224A (fr) * 1969-08-25 1971-02-24 Philips Nv Seringue d'injection
US3811441A (en) * 1972-02-10 1974-05-21 Survival Technology Cartridge syringe
US3867938A (en) 1973-08-01 1975-02-25 Schick Inc Hygienic syringe
US3895633A (en) * 1973-09-27 1975-07-22 Survival Technology Large capacity syringe
US3880163A (en) * 1973-10-26 1975-04-29 Jack H Ritterskamp Medicinal syringe actuating device
US3889673A (en) * 1974-01-02 1975-06-17 Survival Technology Tip assembly for syringes
US4031890A (en) * 1976-01-14 1977-06-28 Survival Technology, Inc. Safety I. V. injector
US4031893A (en) * 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4254768A (en) * 1979-09-14 1981-03-10 Ty Perla J Hypodermic syringe
US4328802A (en) * 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
US4316463A (en) * 1981-01-26 1982-02-23 Vac-O-Cast, Inc. Corrosive protected hypodermic module
FR2506151B1 (fr) 1981-05-20 1985-12-27 Joulia Antoine Dispositif souple de maintien, de correction et de rechauffement cervical
US4624393A (en) 1981-07-02 1986-11-25 Survival Technology, Inc. Split hub assembly for a necked down cartridge tube
US4427039A (en) 1981-12-14 1984-01-24 Brooks William R Mechanical delivery system for a catalyst or the like
US4378015A (en) * 1981-12-21 1983-03-29 Wardlaw Stephen C Automatic injecting syringe
US4468220A (en) 1982-04-05 1984-08-28 Milliken Research Corporation Low flow constant rate pump
US4445510A (en) * 1982-09-13 1984-05-01 Rigby Ronald F Automatic injector for hypodermic syringes or the like and lancet holder for use in conjunction with an automatic injector
FR2539302B1 (fr) * 1983-01-17 1986-03-14 Brunet Jean Louis Seringue a usage medical
DE3417757C2 (de) * 1984-05-12 1994-11-10 Lucas Dieter Dr Injektionsspritze
ATE39325T1 (de) 1984-11-02 1989-01-15 Duphar Int Res Automatische injektionsvorrichtung.
US4645073A (en) 1985-04-02 1987-02-24 Survival Technology, Inc. Anti-contamination hazardous material package
US4689042A (en) * 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4723937A (en) * 1985-05-20 1988-02-09 Survival Technology, Inc. Plural dosage automatic injector with a by-pass fitment
US4838857A (en) 1985-05-29 1989-06-13 Becton, Dickinson And Company Medical infusion device
US4861335A (en) * 1985-07-26 1989-08-29 Duoject Medical Systems Inc. Syringe
US4713061A (en) 1986-07-14 1987-12-15 Survival Technology, Inc. Cartridge with universal plastic hub
DE3715337C2 (de) 1986-11-14 1994-04-14 Haselmeier Wilhelm Fa Injektionsgerät
DE3638984C3 (de) * 1986-11-14 1993-11-18 Haselmeier Wilhelm Fa Injektionsgerät
US4747839A (en) 1986-12-17 1988-05-31 Survival Technology, Inc. Disposable hypodermic syringe with plastic snap-on needle hub and heat shrink seal therefor
US4886495A (en) * 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US4904242A (en) 1987-04-29 1990-02-27 Kulli John C Phlebotomy set with safety retracting needle
US4900307A (en) 1987-04-29 1990-02-13 Kulli John C Safety retracting needle for use with syringe
US4927414A (en) 1987-04-29 1990-05-22 Kulli John C Syringe with safety retracting needle
DE3715258C2 (de) * 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
EP0315656B1 (de) 1987-05-18 1993-07-07 Disetronic Ag Infusionsgerät
FR2616221A1 (fr) 1987-06-02 1988-12-09 Archambeaud Philippe Dispositif d'injection automatique de produits et notamment de produits
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
IL86799A (en) * 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
US4938742A (en) 1988-02-04 1990-07-03 Smits Johannes G Piezoelectric micropump with microvalves
US5156599A (en) * 1988-06-28 1992-10-20 Sherwood Medical Company Syringe and sliding locking needle shield
US4929241A (en) 1988-08-05 1990-05-29 Kulli John C Medical needle puncture guard
US5024656A (en) * 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US4902279A (en) * 1988-10-05 1990-02-20 Autoject Systems Inc. Liquid medicament safety injector
US5244465A (en) * 1988-10-19 1993-09-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Reusable injection device for distributing a preselected dose
US5013303A (en) 1988-11-03 1991-05-07 Yehuda Tamari Constant pressure infusion device
US4923447A (en) * 1989-02-17 1990-05-08 Morgan Michael W Syringe assembly
US5407431A (en) * 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US5188599A (en) * 1989-07-11 1993-02-23 Med-Design, Inc. Retractable needle system
US5106374A (en) 1990-05-08 1992-04-21 Abbott Laboratories Ambulatory infusion device
US5279581A (en) * 1990-05-09 1994-01-18 Firth John R Disposable self-shielding hypodermic syringe
US5169388A (en) 1990-06-07 1992-12-08 Gensia Pharmaceuticals, Inc. Pressure-activated medication dispenser
GB9100819D0 (en) * 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US5709668A (en) * 1991-01-16 1998-01-20 Senetek Plc Automatic medicament injector employing non-coring needle
US5360410A (en) * 1991-01-16 1994-11-01 Senetek Plc Safety syringe for mixing two-component medicaments
US5163909A (en) 1991-01-28 1992-11-17 Alan E. Jordan Medical fluid delivery system
GB9107647D0 (en) * 1991-04-11 1991-05-29 Jeffrey Peter Syringe construction providing needle point protection
DE4112259A1 (de) * 1991-04-15 1992-10-22 Medico Dev Investment Co Injektionsgeraet
GB9111600D0 (en) * 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
EP0518416A1 (en) 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
DE4120267A1 (de) 1991-06-19 1992-12-24 Bader & Partner Medizintechnik Verfahren zum betrieb einer vorrichtung zur abgabe eines fluessigen medizinischen behandlungsstoffes an einen zu behandelnden koerper und vorrichtung zur durchfuehrung des verfahrens
US5207645A (en) 1991-06-25 1993-05-04 Medication Delivery Devices Infusion pump, treatment fluid bag therefor, and method for the use thereof
DE59202070D1 (de) * 1991-07-24 1995-06-08 Medico Dev Investment Co Injektor.
DE4127650C1 (enExample) * 1991-08-21 1993-02-25 Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De
GB9200219D0 (en) * 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
US5201708A (en) * 1992-02-03 1993-04-13 Timothy A. Kershenstine Self-locking safety syringe
US5281198A (en) 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
US5180370A (en) * 1992-05-18 1993-01-19 Gillespie Elgene R Safety hypodermic syringe with retractable needle
US5531683A (en) * 1992-08-13 1996-07-02 Science Incorporated Mixing and delivery syringe assembly
US5267963A (en) * 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
US5545147A (en) * 1992-10-20 1996-08-13 Eli Lilly And Company Anti-backup improvement for hypodermic syringes
US5681291A (en) * 1992-11-19 1997-10-28 Tebro S.A. Disposable auto-injector for prefilled syringes
US5320609A (en) * 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
US5342320A (en) 1993-01-15 1994-08-30 Cameron Robert W Hypodermic syringe having shielding to prevent accidental injury following use
US5545143A (en) 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
US5334162A (en) * 1993-03-15 1994-08-02 Eli Lilly And Company Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same
WO1994021316A1 (en) * 1993-03-24 1994-09-29 Owen Mumford Limited Improvements relating to injection devices
US5746714A (en) 1993-04-05 1998-05-05 P.A.T.H. Air powered needleless hypodermic injector
GB9310163D0 (en) * 1993-05-18 1993-06-30 Owen Mumford Ltd Improvements relating to injection devices
US5695472A (en) * 1993-05-27 1997-12-09 Washington Biotech Corporation Modular automatic or manual emergency medicine injection system
US5342319A (en) 1993-08-17 1994-08-30 Watson Robert L Transdermal injection appliance
US5472430A (en) 1993-08-18 1995-12-05 Vlv Associates Protected needle assembly
FR2715071B1 (fr) * 1994-01-17 1996-03-01 Aguettant Lab Injecteur automatique de médicament.
US5489266A (en) * 1994-01-25 1996-02-06 Becton, Dickinson And Company Syringe assembly and method for lyophilizing and reconstituting injectable medication
US5540665A (en) 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5514097A (en) * 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
JPH07227424A (ja) 1994-02-17 1995-08-29 Japan Storage Battery Co Ltd 流体輸送器
US5411489A (en) 1994-05-06 1995-05-02 Sterling Winthrop Inc. Pre-filled syringe and pre-filled cartridge having actuating cylinder/plunger rod combination for reducing syringing force
US5713872A (en) 1994-06-09 1998-02-03 Feuerborn; Arthur Mark Flexing safety shield for hypodermic needles
US5462525A (en) 1994-06-14 1995-10-31 Minimed, Inc., A Delaware Corporation Flow sensor for an infusion pump
US5460611A (en) 1994-09-06 1995-10-24 Medisys Technologies, Inc. Safety syringe
US5637094A (en) * 1994-11-04 1997-06-10 Pos-T-Vac, Inc. Multiple dosage syringe
NZ302558A (en) * 1995-03-07 1999-11-29 Lilly Co Eli Dispensing apparatus with a medication cartridge with a manually adjustable metering mechanism
US5785682A (en) * 1995-03-22 1998-07-28 Abbott Laboratories Pre-filled syringe drug delivery system
GB9506087D0 (en) * 1995-03-24 1995-05-10 Owen Mumford Ltd Improvements relating to medical injection devices
US5779668A (en) * 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
US5566729A (en) * 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
FR2733155B1 (fr) * 1995-04-18 1997-09-19 Tebro Auto-injecteur rechargeable
CA2229940A1 (en) * 1995-08-22 1997-03-06 Michael J. Botich Pre-filled retractable needle injection ampoules
US6123688A (en) * 1995-08-22 2000-09-26 Mdc Investment Holdings, Inc. Pre-filled retractable needle injection devices
US5688251A (en) * 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US5658259A (en) * 1995-10-19 1997-08-19 Meridian Medical Technologies, Inc. Dental cartridge assembly auto-injector with protective needle cover
US6146361A (en) * 1996-09-26 2000-11-14 Becton Dickinson And Company Medication delivery pen having a 31 gauge needle
US5738665A (en) * 1996-09-26 1998-04-14 Becton, Dickinson And Company Shield and actuator for needles
US5681292A (en) * 1996-10-29 1997-10-28 Retrax Safety Systems, Inc. Retractable needle and syringe combination
US5746215A (en) 1996-11-01 1998-05-05 U.S. Medical Instruments, Inc. IV infusion or collection device with extendable and retractable needle
US6319234B1 (en) * 1997-02-12 2001-11-20 Sergio Restelli Disposable safety syringe
DE29703820U1 (de) * 1997-03-03 1998-07-02 Medico Development Investment Co., Ascona Injektionsgerät
US5882342A (en) * 1997-04-11 1999-03-16 Safety Medical Manufacturing, Inc Safety medical syringe with retractable needle
GB9714948D0 (en) * 1997-07-16 1997-09-17 Owen Mumford Ltd Improvements relating to injection devices
US6149626A (en) * 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
IE970782A1 (en) * 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
FR2770404B1 (fr) 1997-11-05 2000-01-28 Sedat Injecteur automatique a retraction d'aiguille en fin d'injection
DE69827036T2 (de) * 1997-12-16 2006-03-09 Meridian Medical Technologies, Inc. Automatische injektionsvorrichtung zur verabreichung eines medikamentes
IT1304761B1 (it) * 1998-01-20 2001-03-29 Nardino Righi Siringa monouso di sicurezza.
DE29801168U1 (de) * 1998-01-24 1999-08-12 Medico Dev Investment Co Injektionsgerät
US6319233B1 (en) * 1998-04-17 2001-11-20 Becton, Dickinson And Company Safety shield system for prefilled syringes
US6616639B2 (en) * 1998-04-17 2003-09-09 Becton, Dickinson And Company Safety shield system for syringes
GB9808408D0 (en) * 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
DE19822031C2 (de) * 1998-05-15 2000-03-23 Disetronic Licensing Ag Autoinjektionsgerät
FR2778852B1 (fr) 1998-05-19 2000-12-22 Sedat Seringue d'injection a aiguille retractable
SE9803662D0 (sv) * 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
YU49336B (sh) * 1999-07-27 2005-07-19 Pharma Consult Ges.M.B.H. Uređaj za automatsko ubrizgavanje tečnosti za ubrizgavanje
FR2801795B1 (fr) * 1999-12-07 2002-07-05 Plastef Investissements Dispositif de support de securite pour une seringue et ensemble d'un tel dispositif et d'une seringue
GB0003790D0 (en) * 2000-02-18 2000-04-05 Astrazeneca Uk Ltd Medical device
DE10009815B4 (de) * 2000-03-01 2009-07-16 Tecpharma Licensing Ag Injektionsgerät mit einer Nadelabdeckung
US6387078B1 (en) * 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
US6899699B2 (en) * 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
BR0208064A (pt) * 2001-03-13 2006-10-10 Mdc Invest Holdings Inc dispositivo médico, e, processo para injetar medicamento
US20030105430A1 (en) * 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
US7004929B2 (en) * 2002-03-29 2006-02-28 Mdc Investment Holdings, Inc. Safety pre-filled cartridge injector
MY139059A (en) * 2002-06-24 2009-08-28 Alza Corp Reusable, spring driven autoinjector
US7097634B2 (en) * 2002-07-31 2006-08-29 Alza Corporation Injection device providing automatic needle retraction
US6805686B1 (en) * 2003-05-06 2004-10-19 Abbott Laboratories Autoinjector with extendable needle protector shroud
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector

Also Published As

Publication number Publication date
US20050027255A1 (en) 2005-02-03
JP2007500530A (ja) 2007-01-18
EP1654020A1 (en) 2006-05-10
US7717877B2 (en) 2010-05-18
DE602004026197D1 (de) 2010-05-06
WO2005009515A1 (en) 2005-02-03
US20070112310A1 (en) 2007-05-17
EP1654020B1 (en) 2010-03-24

Similar Documents

Publication Publication Date Title
JP4680190B2 (ja) 注射装置
US20070265568A1 (en) Automatic Injector
EP1660158B1 (en) Syringe with automatically triggered safety sleeve
EP3256196B1 (en) Safe auto-needle device
EP2654844B1 (en) Auto-injector
JP4864863B2 (ja) 自動注射器
JP6138129B2 (ja) 注射装置
EP3104909B1 (en) Automatic injection device
EP3103494B1 (en) Safety shield system for a syringe
US20030105430A1 (en) Automatic injector
EP3160547B1 (en) Injection device having needle shield locking
EA023390B1 (ru) Устройство для доставки лекарственных веществ, приводимое в действие ладонью руки
US20210106757A1 (en) Autoinjection device having a memory element
US20250229026A1 (en) Automatic injection device with rotation sensor
EP4410334A1 (en) Safety needle cover lock for an autoinjector
HK1182655B (en) Auto-injector
HK1182655A (en) Auto-injector

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070724

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070724

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100309

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100608

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100615

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100702

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110105

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110202

R150 Certificate of patent or registration of utility model

Ref document number: 4680190

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140210

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term