JP4675017B2 - エキソソーム分離によって精製hcvrnaを調製するための方法 - Google Patents

エキソソーム分離によって精製hcvrnaを調製するための方法 Download PDF

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JP4675017B2
JP4675017B2 JP2001538480A JP2001538480A JP4675017B2 JP 4675017 B2 JP4675017 B2 JP 4675017B2 JP 2001538480 A JP2001538480 A JP 2001538480A JP 2001538480 A JP2001538480 A JP 2001538480A JP 4675017 B2 JP4675017 B2 JP 4675017B2
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hcv
exosome
particles
cell culture
antibody
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JP2003514523A5 (enExample
JP2003514523A (ja
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セルジョ アブリニューニ,
ピエロ ピレリ,
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カイロン ソチエタ ア レスポンサビリタ リミタータ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24251—Methods of production or purification of viral material

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2001538480A 1999-11-18 2000-11-20 エキソソーム分離によって精製hcvrnaを調製するための方法 Expired - Fee Related JP4675017B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9927320.3A GB9927320D0 (en) 1999-11-18 1999-11-18 Exosome separation
GB9927320.3 1999-11-18
PCT/IB2000/001801 WO2001036601A1 (en) 1999-11-18 2000-11-20 Method for the preparation of purified hcv rna by exosome separation

Publications (3)

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JP2003514523A JP2003514523A (ja) 2003-04-22
JP2003514523A5 JP2003514523A5 (enExample) 2007-11-22
JP4675017B2 true JP4675017B2 (ja) 2011-04-20

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US (2) US7198923B1 (enExample)
EP (1) EP1230347B1 (enExample)
JP (1) JP4675017B2 (enExample)
AT (1) ATE373084T1 (enExample)
AU (1) AU1721801A (enExample)
CA (1) CA2392075C (enExample)
CY (1) CY1107521T1 (enExample)
DE (1) DE60036403T2 (enExample)
DK (1) DK1230347T3 (enExample)
ES (1) ES2292489T3 (enExample)
GB (1) GB9927320D0 (enExample)
PT (1) PT1230347E (enExample)
WO (1) WO2001036601A1 (enExample)

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US7198923B1 (en) 2007-04-03
AU1721801A (en) 2001-05-30
DK1230347T3 (da) 2007-11-05
JP2003514523A (ja) 2003-04-22
CA2392075A1 (en) 2001-05-25
CY1107521T1 (el) 2013-03-13
WO2001036601A1 (en) 2001-05-25
US20070254351A1 (en) 2007-11-01
EP1230347B1 (en) 2007-09-12
CA2392075C (en) 2011-01-04
PT1230347E (pt) 2007-12-20
GB9927320D0 (en) 2000-01-12
US7807438B2 (en) 2010-10-05
DE60036403T2 (de) 2008-06-12
ATE373084T1 (de) 2007-09-15
DE60036403D1 (de) 2007-10-25
ES2292489T3 (es) 2008-03-16
EP1230347A1 (en) 2002-08-14

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