GB9927320D0 - Exosome separation - Google Patents
Exosome separationInfo
- Publication number
- GB9927320D0 GB9927320D0 GBGB9927320.3A GB9927320A GB9927320D0 GB 9927320 D0 GB9927320 D0 GB 9927320D0 GB 9927320 A GB9927320 A GB 9927320A GB 9927320 D0 GB9927320 D0 GB 9927320D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- exosome separation
- hepatitis
- virus
- separation
- exosome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000001808 exosome Anatomy 0.000 title abstract 3
- 238000000926 separation method Methods 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 210000002381 plasma Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24251—Methods of production or purification of viral material
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9927320.3A GB9927320D0 (en) | 1999-11-18 | 1999-11-18 | Exosome separation |
| PCT/IB2000/001801 WO2001036601A1 (en) | 1999-11-18 | 2000-11-20 | Method for the preparation of purified hcv rna by exosome separation |
| US10/130,467 US7198923B1 (en) | 1999-11-18 | 2000-11-20 | Method for the preparation of purified HCV RNA by exosome separation |
| EP00979837A EP1230347B1 (en) | 1999-11-18 | 2000-11-20 | Method for the preparation of purified hcv rna by exosome separation |
| JP2001538480A JP4675017B2 (ja) | 1999-11-18 | 2000-11-20 | エキソソーム分離によって精製hcvrnaを調製するための方法 |
| DK00979837T DK1230347T3 (da) | 1999-11-18 | 2000-11-20 | Fremgangsmåde til fremstilling af oprenset HCV-RNA ved exosomseparering |
| PT00979837T PT1230347E (pt) | 1999-11-18 | 2000-11-20 | Método de preparação de rna do hcv purificado por separação de exossomas |
| DE60036403T DE60036403T2 (de) | 1999-11-18 | 2000-11-20 | Verfahren zur Herstellung von gereinigter HCV-RNA durch Isolierung von Exosomen |
| AU17218/01A AU1721801A (en) | 1999-11-18 | 2000-11-20 | Method for the preparation of purified hcv rna by exosome separation |
| AT00979837T ATE373084T1 (de) | 1999-11-18 | 2000-11-20 | Verfahren zur herstellung von gereinigtem hcv rna durch isolierung von exosomen |
| CA2392075A CA2392075C (en) | 1999-11-18 | 2000-11-20 | Method for the preparation of purified hcv rna by exosome separation |
| ES00979837T ES2292489T3 (es) | 1999-11-18 | 2000-11-20 | Procedimiento para la preparacion de arn de vhc purificado por separacion de exosomas. |
| US11/699,925 US7807438B2 (en) | 1999-11-18 | 2007-01-30 | Preparation of purified exosomes comprising HCV RNA |
| CY20071101559T CY1107521T1 (el) | 1999-11-18 | 2007-12-07 | Μεθοδος για την παρασκευη καθαρισμενου hcv rna με διαχωρισμο εξωσωματων |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9927320.3A GB9927320D0 (en) | 1999-11-18 | 1999-11-18 | Exosome separation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9927320D0 true GB9927320D0 (en) | 2000-01-12 |
Family
ID=10864765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9927320.3A Ceased GB9927320D0 (en) | 1999-11-18 | 1999-11-18 | Exosome separation |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7198923B1 (enExample) |
| EP (1) | EP1230347B1 (enExample) |
| JP (1) | JP4675017B2 (enExample) |
| AT (1) | ATE373084T1 (enExample) |
| AU (1) | AU1721801A (enExample) |
| CA (1) | CA2392075C (enExample) |
| CY (1) | CY1107521T1 (enExample) |
| DE (1) | DE60036403T2 (enExample) |
| DK (1) | DK1230347T3 (enExample) |
| ES (1) | ES2292489T3 (enExample) |
| GB (1) | GB9927320D0 (enExample) |
| PT (1) | PT1230347E (enExample) |
| WO (1) | WO2001036601A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110123841A (zh) * | 2018-02-09 | 2019-08-16 | 上海市第六人民医院 | 负载白藜芦醇的人多能干细胞外泌体在制备治疗生殖系统疾病药物的用途 |
| CN110123838A (zh) * | 2018-02-02 | 2019-08-16 | 上海睿泰生物科技股份有限公司 | 负载白藜芦醇的人多能干细胞外泌体及其制备方法与用途 |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9927320D0 (en) * | 1999-11-18 | 2000-01-12 | Chiron Spa | Exosome separation |
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| WO2005121369A2 (en) * | 2004-06-02 | 2005-12-22 | Sourcepharm, Inc. | Rna-containing microvesicles and methods therefor |
| ES2880460T3 (es) * | 2006-03-09 | 2021-11-24 | Aethlon Medical Inc | Eliminación extracorpórea de partículas microvesiculares |
| US9085778B2 (en) * | 2006-05-03 | 2015-07-21 | VL27, Inc. | Exosome transfer of nucleic acids to cells |
| US8617806B2 (en) * | 2008-01-25 | 2013-12-31 | Hansabiomed Ou | Method to measure and characterize microvesicles in the human body fluids |
| AU2009212543B2 (en) * | 2008-02-01 | 2015-07-09 | The General Hospital Corporation | Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions |
| US11266736B2 (en) | 2008-04-17 | 2022-03-08 | Vin De Bona Trading Company Pte Ltd | Method of painting micro vesicles |
| AU2009259893A1 (en) * | 2008-06-20 | 2009-12-23 | Proxy Life Science Holdings, Inc. | Microvesicle-based compositions and methods |
| US9487837B2 (en) | 2008-10-06 | 2016-11-08 | Morehouse School Of Medicine | Exosome-mediated diagnosis of hepatitis virus infections and diseases |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| JP2012507300A (ja) | 2008-10-30 | 2012-03-29 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | Rnaパターンを評価する方法 |
| EP2350320A4 (en) * | 2008-11-12 | 2012-11-14 | Caris Life Sciences Luxembourg Holdings | METHOD AND SYSTEMS FOR USE OF EXOSOMES FOR THE DETERMINATION OF PHENOTYPES |
| PT2419144T (pt) * | 2009-04-17 | 2019-09-16 | Univ Oxford Innovation Ltd | Composição para a administração de material genético |
| BRPI0900815A2 (pt) * | 2009-04-23 | 2010-12-28 | Sociedade Benef Israelita Bras Hospital Albert Einstein | método para isolamento de exossomos a partir de soluções biológicas utilizando nanopartìculas de óxido de ferro |
| DK2454588T3 (en) | 2009-07-16 | 2015-09-28 | Gen Hospital Corp | Nucleic acid |
| EP2475988B1 (en) | 2009-09-09 | 2018-11-14 | The General Hospital Corporation | Use of microvesicles in analyzing nucleic acid profiles |
| US20130029339A1 (en) | 2009-09-09 | 2013-01-31 | The General Hospital Corporation | Use of microvesicles in analyzing kras mutations |
| WO2011049059A1 (ja) * | 2009-10-22 | 2011-04-28 | 国立大学法人岐阜大学 | Rna内包キャリア組成物 |
| CA2782284A1 (en) | 2009-11-30 | 2011-06-03 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems for isolating, storing, and analyzing vesicles |
| AU2011223789A1 (en) | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| JP5755326B2 (ja) | 2010-06-11 | 2015-07-29 | 日立化成株式会社 | 腎機能の特徴を決定する方法 |
| WO2011156734A2 (en) * | 2010-06-11 | 2011-12-15 | Hitachi Chemical Co., Ltd. | Method of characterizing vascular diseases |
| WO2012006476A2 (en) | 2010-07-07 | 2012-01-12 | Aethlon Medical, Inc. | Methods and compositions for quantifying exosomes |
| WO2012031008A2 (en) | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| CA2817111C (en) | 2010-11-10 | 2019-03-05 | Exosome Diagnostics, Inc. | Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom |
| CA2835641C (en) | 2011-05-11 | 2019-05-28 | Exosome Diagnostics, Inc. | Nucleic acid extraction from heterogeneous biological materials |
| WO2012170037A1 (en) | 2011-06-10 | 2012-12-13 | Hitachi Chemical Co., Ltd. | Vesicle capturing devices and methods for using same |
| CA2839896A1 (en) | 2011-06-21 | 2012-12-27 | Alnylam Pharmaceuticals, Inc. | Assays and methods for determining activity of a therapeutic agent in a subject |
| EP3492606B1 (en) | 2011-08-22 | 2023-10-04 | Exosome Diagnostics, Inc. | Urine biomarkers |
| KR20140076571A (ko) * | 2011-09-22 | 2014-06-20 | 유니버시다드 데 로스 안데스 | 급성 신장 손상의 조기 모니터링, 진단 및/또는 예후 방법 |
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| US11136627B2 (en) | 2012-08-30 | 2021-10-05 | Exosome Diagnostics, Inc. | Controls for nucleic acid assays |
| US20150252428A1 (en) | 2012-10-03 | 2015-09-10 | Exosome Diagnostics, Inc. | Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions |
| US20150233800A1 (en) | 2012-10-11 | 2015-08-20 | Vin-De-Bona Trading Company Pte Ltd | Method of painting microvesicles |
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| US12558316B2 (en) | 2013-03-13 | 2026-02-24 | University Of Miami | Methods and compositions for the treatment of epidermolysis bullosa |
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| GB9517926D0 (en) | 1995-09-01 | 1995-11-01 | Biocine Spa | Binding protein |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| WO1999018198A1 (en) | 1997-10-06 | 1999-04-15 | Chiron S.P.A. | Hepatitis c receptor protein cd81 |
| CA2305715A1 (en) * | 1997-11-06 | 1999-05-20 | Innogenetics N.V. | Host derived proteins binding hcv: medical, diagnostic and purification use |
| GB9927320D0 (en) * | 1999-11-18 | 2000-01-12 | Chiron Spa | Exosome separation |
-
1999
- 1999-11-18 GB GBGB9927320.3A patent/GB9927320D0/en not_active Ceased
-
2000
- 2000-11-20 US US10/130,467 patent/US7198923B1/en not_active Expired - Lifetime
- 2000-11-20 DE DE60036403T patent/DE60036403T2/de not_active Expired - Lifetime
- 2000-11-20 EP EP00979837A patent/EP1230347B1/en not_active Expired - Lifetime
- 2000-11-20 ES ES00979837T patent/ES2292489T3/es not_active Expired - Lifetime
- 2000-11-20 CA CA2392075A patent/CA2392075C/en not_active Expired - Lifetime
- 2000-11-20 JP JP2001538480A patent/JP4675017B2/ja not_active Expired - Fee Related
- 2000-11-20 AU AU17218/01A patent/AU1721801A/en not_active Abandoned
- 2000-11-20 DK DK00979837T patent/DK1230347T3/da active
- 2000-11-20 WO PCT/IB2000/001801 patent/WO2001036601A1/en not_active Ceased
- 2000-11-20 AT AT00979837T patent/ATE373084T1/de active
- 2000-11-20 PT PT00979837T patent/PT1230347E/pt unknown
-
2007
- 2007-01-30 US US11/699,925 patent/US7807438B2/en not_active Expired - Fee Related
- 2007-12-07 CY CY20071101559T patent/CY1107521T1/el unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110123838A (zh) * | 2018-02-02 | 2019-08-16 | 上海睿泰生物科技股份有限公司 | 负载白藜芦醇的人多能干细胞外泌体及其制备方法与用途 |
| CN110123841A (zh) * | 2018-02-09 | 2019-08-16 | 上海市第六人民医院 | 负载白藜芦醇的人多能干细胞外泌体在制备治疗生殖系统疾病药物的用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| US7198923B1 (en) | 2007-04-03 |
| AU1721801A (en) | 2001-05-30 |
| DK1230347T3 (da) | 2007-11-05 |
| JP2003514523A (ja) | 2003-04-22 |
| JP4675017B2 (ja) | 2011-04-20 |
| CA2392075A1 (en) | 2001-05-25 |
| CY1107521T1 (el) | 2013-03-13 |
| WO2001036601A1 (en) | 2001-05-25 |
| US20070254351A1 (en) | 2007-11-01 |
| EP1230347B1 (en) | 2007-09-12 |
| CA2392075C (en) | 2011-01-04 |
| PT1230347E (pt) | 2007-12-20 |
| US7807438B2 (en) | 2010-10-05 |
| DE60036403T2 (de) | 2008-06-12 |
| ATE373084T1 (de) | 2007-09-15 |
| DE60036403D1 (de) | 2007-10-25 |
| ES2292489T3 (es) | 2008-03-16 |
| EP1230347A1 (en) | 2002-08-14 |
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| AT | Applications terminated before publication under section 16(1) |