JP4601143B2 - 新規酵素遺伝子およびその発現産物 - Google Patents

新規酵素遺伝子およびその発現産物 Download PDF

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Publication number
JP4601143B2
JP4601143B2 JP2000290679A JP2000290679A JP4601143B2 JP 4601143 B2 JP4601143 B2 JP 4601143B2 JP 2000290679 A JP2000290679 A JP 2000290679A JP 2000290679 A JP2000290679 A JP 2000290679A JP 4601143 B2 JP4601143 B2 JP 4601143B2
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Japan
Prior art keywords
gene
gfat1l
protein
present
gfat
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Expired - Fee Related
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JP2000290679A
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English (en)
Japanese (ja)
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JP2002065284A5 (enExample
JP2002065284A (ja
Inventor
力 藤原
考史 岡本
正史 新美
弘之 急式
恵史 山本
篤則 植山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2000290679A priority Critical patent/JP4601143B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to KR1020027016418A priority patent/KR100882407B1/ko
Priority to DE60135650T priority patent/DE60135650D1/de
Priority to CNB018111114A priority patent/CN100390286C/zh
Priority to DK01938602T priority patent/DK1291429T3/da
Priority to CA2412880A priority patent/CA2412880C/en
Priority to EP01938602A priority patent/EP1291429B1/en
Priority to PCT/JP2001/004941 priority patent/WO2001096574A1/ja
Priority to ES01938602T priority patent/ES2312442T3/es
Priority to AU2001264245A priority patent/AU2001264245B2/en
Priority to ARP010102776A priority patent/AR029130A1/es
Priority to US10/297,599 priority patent/US7091018B2/en
Priority to AU6424501A priority patent/AU6424501A/xx
Priority to AT01938602T priority patent/ATE407212T1/de
Priority to PT01938602T priority patent/PT1291429E/pt
Priority to TW090125551A priority patent/TWI232883B/zh
Publication of JP2002065284A publication Critical patent/JP2002065284A/ja
Publication of JP2002065284A5 publication Critical patent/JP2002065284A5/ja
Application granted granted Critical
Publication of JP4601143B2 publication Critical patent/JP4601143B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000290679A 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物 Expired - Fee Related JP4601143B2 (ja)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物
AU6424501A AU6424501A (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
CNB018111114A CN100390286C (zh) 2000-06-13 2001-06-12 新酶基因及其表达产物
DK01938602T DK1291429T3 (da) 2000-06-13 2001-06-12 Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt
CA2412880A CA2412880C (en) 2000-06-13 2001-06-12 Glutamine fructose-6-phosphate amidotransferase splice variant and its expression product
EP01938602A EP1291429B1 (en) 2000-06-13 2001-06-12 Glutamine fructose-6-phosphate amidotransferase splice variant and its expression product
PCT/JP2001/004941 WO2001096574A1 (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
ES01938602T ES2312442T3 (es) 2000-06-13 2001-06-12 Variante alternativa de corte y empalme de glutamina fructosa-6-fosfato amidotransferasa y su producto de expresion.
KR1020027016418A KR100882407B1 (ko) 2000-06-13 2001-06-12 신규 효소 유전자 및 그의 발현 생산물
ARP010102776A AR029130A1 (es) 2000-06-13 2001-06-12 Gen enzimatico y sus productos de expresion
US10/297,599 US7091018B2 (en) 2000-06-13 2001-06-12 Enzyme gene and its expression product
DE60135650T DE60135650D1 (de) 2000-06-13 2001-06-12 Amidotransferase und dessen expressionsprodukt
AT01938602T ATE407212T1 (de) 2000-06-13 2001-06-12 Spleissvariante der glutamine fructose-6- phosphate amidotransferase und dessen expressionsprodukt
PT01938602T PT1291429E (pt) 2000-06-13 2001-06-12 Variante de splicing da glutamina-frutose-6-fosfatoamidotransferase e seu produto de expressão
AU2001264245A AU2001264245B2 (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
TW090125551A TWI232883B (en) 2000-06-13 2001-10-16 Novel enzyme gene and expression product thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-176631 2000-06-13
JP2000176631 2000-06-13
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物

Publications (3)

Publication Number Publication Date
JP2002065284A JP2002065284A (ja) 2002-03-05
JP2002065284A5 JP2002065284A5 (enExample) 2007-09-13
JP4601143B2 true JP4601143B2 (ja) 2010-12-22

Family

ID=26593812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000290679A Expired - Fee Related JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物

Country Status (15)

Country Link
US (1) US7091018B2 (enExample)
EP (1) EP1291429B1 (enExample)
JP (1) JP4601143B2 (enExample)
KR (1) KR100882407B1 (enExample)
CN (1) CN100390286C (enExample)
AR (1) AR029130A1 (enExample)
AT (1) ATE407212T1 (enExample)
AU (2) AU2001264245B2 (enExample)
CA (1) CA2412880C (enExample)
DE (1) DE60135650D1 (enExample)
DK (1) DK1291429T3 (enExample)
ES (1) ES2312442T3 (enExample)
PT (1) PT1291429E (enExample)
TW (1) TWI232883B (enExample)
WO (1) WO2001096574A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE506614T1 (de) * 2005-06-20 2011-05-15 Exelixis Inc Gfats als modifikatoren des axin-wegs und verwendungsverfahren
US8106256B2 (en) * 2005-10-05 2012-01-31 Bayer Cropscience Ag Methods and means for producing hyaluronan
KR101430773B1 (ko) * 2006-06-30 2014-08-18 홋카이도 시스테무 사이엔스 가부시키가이샤 핵산 도입용 조성물
CN103301447B (zh) * 2013-06-25 2014-12-31 哈尔滨医科大学 DNA-PKcs在制备改变肿瘤细胞对MTX耐药性的药物中的应用
CN112980914A (zh) * 2019-12-12 2021-06-18 中国科学院大连化学物理研究所 Gfpt1基因作为靶点在筛选抗肿瘤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
JPH1018683A (ja) * 1996-06-29 1998-01-20 Tesco Joho Center:Kk 吊下扉のレール装置
US5876713A (en) * 1996-08-13 1999-03-02 Takeda Chemical Industries Ltd Glutamine: fructose-6-phosphate amidotransferase, its production and use
JP4175680B2 (ja) * 1996-08-13 2008-11-05 武田薬品工業株式会社 新規タンパク質およびそのｄｎａ
AU2216300A (en) * 1998-12-22 2000-07-12 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids

Also Published As

Publication number Publication date
ES2312442T3 (es) 2009-03-01
DK1291429T3 (da) 2009-01-19
EP1291429A4 (en) 2004-05-26
EP1291429A1 (en) 2003-03-12
US20040132020A1 (en) 2004-07-08
CA2412880A1 (en) 2002-12-13
DE60135650D1 (de) 2008-10-16
TWI232883B (en) 2005-05-21
ATE407212T1 (de) 2008-09-15
PT1291429E (pt) 2008-12-15
AU6424501A (en) 2001-12-24
EP1291429B1 (en) 2008-09-03
CA2412880C (en) 2010-05-04
AU2001264245B2 (en) 2006-04-27
KR100882407B1 (ko) 2009-02-05
US7091018B2 (en) 2006-08-15
WO2001096574A1 (en) 2001-12-20
JP2002065284A (ja) 2002-03-05
CN1436239A (zh) 2003-08-13
KR20030011868A (ko) 2003-02-11
AR029130A1 (es) 2003-06-04
CN100390286C (zh) 2008-05-28

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