DK1291429T3 - Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt - Google Patents

Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt

Info

Publication number
DK1291429T3
DK1291429T3 DK01938602T DK01938602T DK1291429T3 DK 1291429 T3 DK1291429 T3 DK 1291429T3 DK 01938602 T DK01938602 T DK 01938602T DK 01938602 T DK01938602 T DK 01938602T DK 1291429 T3 DK1291429 T3 DK 1291429T3
Authority
DK
Denmark
Prior art keywords
gene
expression product
amino acid
protein
fructose
Prior art date
Application number
DK01938602T
Other languages
English (en)
Inventor
Yasuchika Yamamoto
Takashi Okamoto
Tsutomu Fujiwara
Masashi Niimi
Hiroyuki Kyushiki
Atsunori Ueyama
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK1291429T3 publication Critical patent/DK1291429T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK01938602T 2000-06-13 2001-06-12 Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt DK1291429T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000176631 2000-06-13
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物
PCT/JP2001/004941 WO2001096574A1 (fr) 2000-06-13 2001-06-12 Nouveau gene enzymatique et son produit d'expression

Publications (1)

Publication Number Publication Date
DK1291429T3 true DK1291429T3 (da) 2009-01-19

Family

ID=26593812

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01938602T DK1291429T3 (da) 2000-06-13 2001-06-12 Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt

Country Status (15)

Country Link
US (1) US7091018B2 (da)
EP (1) EP1291429B1 (da)
JP (1) JP4601143B2 (da)
KR (1) KR100882407B1 (da)
CN (1) CN100390286C (da)
AR (1) AR029130A1 (da)
AT (1) ATE407212T1 (da)
AU (2) AU6424501A (da)
CA (1) CA2412880C (da)
DE (1) DE60135650D1 (da)
DK (1) DK1291429T3 (da)
ES (1) ES2312442T3 (da)
PT (1) PT1291429E (da)
TW (1) TWI232883B (da)
WO (1) WO2001096574A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2612143A1 (en) * 2005-06-20 2007-01-04 Exelixis, Inc. Gfats as modifiers of the axin pathway and methods of use
CA2624973C (en) * 2005-10-05 2016-01-19 Bayer Cropscience Ag Production of hyaluronan from plants transgenic for hyaluronan synthase, gfat and udp-glucose dehydrogenase
CN101479384B (zh) * 2006-06-30 2012-11-07 北海道系统·科技株式会社 核酸导入用组合物
CN103301447B (zh) * 2013-06-25 2014-12-31 哈尔滨医科大学 DNA-PKcs在制备改变肿瘤细胞对MTX耐药性的药物中的应用
CN112980914A (zh) * 2019-12-12 2021-06-18 中国科学院大连化学物理研究所 Gfpt1基因作为靶点在筛选抗肿瘤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
JPH1018683A (ja) * 1996-06-29 1998-01-20 Tesco Joho Center:Kk 吊下扉のレール装置
JP4175680B2 (ja) * 1996-08-13 2008-11-05 武田薬品工業株式会社 新規タンパク質およびそのｄｎａ
US5876713A (en) * 1996-08-13 1999-03-02 Takeda Chemical Industries Ltd Glutamine: fructose-6-phosphate amidotransferase, its production and use
AU2216300A (en) * 1998-12-22 2000-07-12 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids

Also Published As

Publication number Publication date
AU2001264245B2 (en) 2006-04-27
CA2412880C (en) 2010-05-04
TWI232883B (en) 2005-05-21
AR029130A1 (es) 2003-06-04
EP1291429A1 (en) 2003-03-12
EP1291429A4 (en) 2004-05-26
PT1291429E (pt) 2008-12-15
JP2002065284A (ja) 2002-03-05
ES2312442T3 (es) 2009-03-01
US20040132020A1 (en) 2004-07-08
AU6424501A (en) 2001-12-24
WO2001096574A1 (fr) 2001-12-20
KR20030011868A (ko) 2003-02-11
KR100882407B1 (ko) 2009-02-05
ATE407212T1 (de) 2008-09-15
JP4601143B2 (ja) 2010-12-22
CN1436239A (zh) 2003-08-13
CN100390286C (zh) 2008-05-28
EP1291429B1 (en) 2008-09-03
CA2412880A1 (en) 2002-12-13
US7091018B2 (en) 2006-08-15
DE60135650D1 (de) 2008-10-16

Similar Documents

Publication Publication Date Title
RU2468080C2 (ru) Новый класс терапевтических белковых молекул
DE69531889D1 (de) Biologisch aktive Fragmente des Glucagon ähnlichen, insulinotropen Peptides
JP2002206000A5 (da)
ATE146219T1 (de) Polypeptid
ATE64619T1 (de) Menschliches apolipoprotein a1 sowie dessen variante, exprimiert in escherichia coli.
WO2001092497A3 (en) Human pancreatic islet glucose-6-phosphatase
DE3587407D1 (de) Toxin-segment des kristallgens vom bacillus thuringiensis.
WO2002061076A1 (en) Adiponectin-associated protein
WO2004053059A3 (en) Mitoneet polypeptide from mitochondrial membranes, modulators thereof, and methods of using the same
DK1291429T3 (da) Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt
KR980002066A (ko) 변이형 인간 성장호르몬 및 그의 용도
EP1284297A3 (en) Identification and use of molecules implicated in pain
EP1279744A3 (en) Identification and use of molecules implicated in pain
DE60336353D1 (de) Rekombinantes protein mit krebsunterdrückender wirkung, sein codierendes gen und seine verwendung
DE60127113D1 (de) Gd3 mimetische peptide
SE8801723D0 (sv) Fibronectin binding protein as well as its preparation
DE69925116D1 (de) Neue, physiologisch aktive peptide und ihre verwendung.
JP2003113111A5 (da)
RU97104072A (ru) Модуляторы веса тела, соответствующие нуклеиновые кислоты и протеины, а также их применение для диагностических и терапевтических целей
RU2003129163A (ru) Полинуклеотид, который можно использовать для модулирования пролиферации раковых клеток
EP0887410A3 (en) DNA encoding a plasminogen activating protein
WO2002088378A3 (en) 66784, a novel human potassium channel and uses therefor
DE60036676D1 (de) G-protein-gekoppelter rezeptor-ähnliche proteine
ATE514710T1 (de) Akap18 delta, eine neue spleissvariante eines proteinkinase a-ankerproteins und verwendung dieser
ATE444362T1 (de) Onkogen, davon abgeleitetes rekombinantes protein und dessen verwendung