TWI232883B - Novel enzyme gene and expression product thereof - Google Patents

Novel enzyme gene and expression product thereof Download PDF

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Publication number
TWI232883B
TWI232883B TW090125551A TW90125551A TWI232883B TW I232883 B TWI232883 B TW I232883B TW 090125551 A TW090125551 A TW 090125551A TW 90125551 A TW90125551 A TW 90125551A TW I232883 B TWI232883 B TW I232883B
Authority
TW
Taiwan
Prior art keywords
gene
protein
amino acid
gfat1l
leu
Prior art date
Application number
TW090125551A
Other languages
English (en)
Chinese (zh)
Inventor
Tsutomu Fujiwara
Takashi Okamoto
Masashi Niimi
Hiroyuki Kyushiki
Yasuchika Yamamoto
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of TWI232883B publication Critical patent/TWI232883B/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1096Transferases (2.) transferring nitrogenous groups (2.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
TW090125551A 2000-06-13 2001-10-16 Novel enzyme gene and expression product thereof TWI232883B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000176631 2000-06-13
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物

Publications (1)

Publication Number Publication Date
TWI232883B true TWI232883B (en) 2005-05-21

Family

ID=26593812

Family Applications (1)

Application Number Title Priority Date Filing Date
TW090125551A TWI232883B (en) 2000-06-13 2001-10-16 Novel enzyme gene and expression product thereof

Country Status (15)

Country Link
US (1) US7091018B2 (enExample)
EP (1) EP1291429B1 (enExample)
JP (1) JP4601143B2 (enExample)
KR (1) KR100882407B1 (enExample)
CN (1) CN100390286C (enExample)
AR (1) AR029130A1 (enExample)
AT (1) ATE407212T1 (enExample)
AU (2) AU2001264245B2 (enExample)
CA (1) CA2412880C (enExample)
DE (1) DE60135650D1 (enExample)
DK (1) DK1291429T3 (enExample)
ES (1) ES2312442T3 (enExample)
PT (1) PT1291429E (enExample)
TW (1) TWI232883B (enExample)
WO (1) WO2001096574A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE506614T1 (de) * 2005-06-20 2011-05-15 Exelixis Inc Gfats als modifikatoren des axin-wegs und verwendungsverfahren
US8106256B2 (en) * 2005-10-05 2012-01-31 Bayer Cropscience Ag Methods and means for producing hyaluronan
KR101430773B1 (ko) * 2006-06-30 2014-08-18 홋카이도 시스테무 사이엔스 가부시키가이샤 핵산 도입용 조성물
CN103301447B (zh) * 2013-06-25 2014-12-31 哈尔滨医科大学 DNA-PKcs在制备改变肿瘤细胞对MTX耐药性的药物中的应用
CN112980914A (zh) * 2019-12-12 2021-06-18 中国科学院大连化学物理研究所 Gfpt1基因作为靶点在筛选抗肿瘤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
JPH1018683A (ja) * 1996-06-29 1998-01-20 Tesco Joho Center:Kk 吊下扉のレール装置
US5876713A (en) * 1996-08-13 1999-03-02 Takeda Chemical Industries Ltd Glutamine: fructose-6-phosphate amidotransferase, its production and use
JP4175680B2 (ja) * 1996-08-13 2008-11-05 武田薬品工業株式会社 新規タンパク質およびそのdna
AU2216300A (en) * 1998-12-22 2000-07-12 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids

Also Published As

Publication number Publication date
ES2312442T3 (es) 2009-03-01
DK1291429T3 (da) 2009-01-19
EP1291429A4 (en) 2004-05-26
JP4601143B2 (ja) 2010-12-22
EP1291429A1 (en) 2003-03-12
US20040132020A1 (en) 2004-07-08
CA2412880A1 (en) 2002-12-13
DE60135650D1 (de) 2008-10-16
ATE407212T1 (de) 2008-09-15
PT1291429E (pt) 2008-12-15
AU6424501A (en) 2001-12-24
EP1291429B1 (en) 2008-09-03
CA2412880C (en) 2010-05-04
AU2001264245B2 (en) 2006-04-27
KR100882407B1 (ko) 2009-02-05
US7091018B2 (en) 2006-08-15
WO2001096574A1 (en) 2001-12-20
JP2002065284A (ja) 2002-03-05
CN1436239A (zh) 2003-08-13
KR20030011868A (ko) 2003-02-11
AR029130A1 (es) 2003-06-04
CN100390286C (zh) 2008-05-28

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