JP4511939B2 - ベンゾフラン誘導体、その製造方法およびその中間体 - Google Patents

ベンゾフラン誘導体、その製造方法およびその中間体 Download PDF

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Publication number
JP4511939B2
JP4511939B2 JP2004552856A JP2004552856A JP4511939B2 JP 4511939 B2 JP4511939 B2 JP 4511939B2 JP 2004552856 A JP2004552856 A JP 2004552856A JP 2004552856 A JP2004552856 A JP 2004552856A JP 4511939 B2 JP4511939 B2 JP 4511939B2
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compound
formula
alkyl
methyl
glk
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Japanese (ja)
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JP2006509749A5 (enExample
JP2006509749A (ja
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マッケレッチャー，ダーレン
レイナー，ジョン・ウォール
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AstraZeneca AB
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AstraZeneca AB
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
JP2004552856A 2002-11-19 2003-11-13 ベンゾフラン誘導体、その製造方法およびその中間体 Expired - Fee Related JP4511939B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0226930.6A GB0226930D0 (en) 2002-11-19 2002-11-19 Chemical compounds
PCT/GB2003/004919 WO2004046139A1 (en) 2002-11-19 2003-11-13 Benzofuran derivates, process for their preparation and intermediates thereof

Publications (3)

Publication Number Publication Date
JP2006509749A JP2006509749A (ja) 2006-03-23
JP2006509749A5 JP2006509749A5 (enExample) 2006-10-19
JP4511939B2 true JP4511939B2 (ja) 2010-07-28

Family

ID=9948089

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004552856A Expired - Fee Related JP4511939B2 (ja) 2002-11-19 2003-11-13 ベンゾフラン誘導体、その製造方法およびその中間体

Country Status (9)

Country Link
US (1) US7709505B2 (enExample)
EP (1) EP1578745B1 (enExample)
JP (1) JP4511939B2 (enExample)
AT (1) ATE378332T1 (enExample)
AU (1) AU2003282234A1 (enExample)
DE (1) DE60317562T2 (enExample)
ES (1) ES2293045T3 (enExample)
GB (1) GB0226930D0 (enExample)
WO (1) WO2004046139A1 (enExample)

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JP2013520502A (ja) 2010-02-25 2013-06-06 メルク・シャープ・エンド・ドーム・コーポレイション 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
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US7709505B2 (en) 2010-05-04
ES2293045T3 (es) 2008-03-16
AU2003282234A1 (en) 2004-06-15
GB0226930D0 (en) 2002-12-24
ATE378332T1 (de) 2007-11-15
DE60317562D1 (de) 2007-12-27
JP2006509749A (ja) 2006-03-23
DE60317562T2 (de) 2008-10-23
EP1578745A1 (en) 2005-09-28
EP1578745B1 (en) 2007-11-14
US20060058353A1 (en) 2006-03-16

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