JP4476362B2 - 生物学的に活性なペプチドのミルクからの精製 - Google Patents
生物学的に活性なペプチドのミルクからの精製 Download PDFInfo
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- JP4476362B2 JP4476362B2 JP54103697A JP54103697A JP4476362B2 JP 4476362 B2 JP4476362 B2 JP 4476362B2 JP 54103697 A JP54103697 A JP 54103697A JP 54103697 A JP54103697 A JP 54103697A JP 4476362 B2 JP4476362 B2 JP 4476362B2
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Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/832—Milk; colostrum
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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| US08/648,235 | 1996-05-13 | ||
| US08/648,235 US6268487B1 (en) | 1996-05-13 | 1996-05-13 | Purification of biologically active peptides from milk |
| PCT/US1997/008044 WO1997042835A1 (en) | 1996-05-13 | 1997-05-13 | Purification of biologically active peptides from milk |
Publications (3)
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| JP2000510701A JP2000510701A (ja) | 2000-08-22 |
| JP2000510701A5 JP2000510701A5 (cg-RX-API-DMAC7.html) | 2005-01-13 |
| JP4476362B2 true JP4476362B2 (ja) | 2010-06-09 |
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| JP54103697A Expired - Lifetime JP4476362B2 (ja) | 1996-05-13 | 1997-05-13 | 生物学的に活性なペプチドのミルクからの精製 |
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| EP1555319A3 (en) | 1997-10-20 | 2006-03-15 | GTC Biotherapeutics, Inc. | Modified nucleic acid sequences and method to increasing mRNA levels and protein expression in cell systems |
| SE9802213D0 (sv) * | 1998-06-18 | 1998-06-18 | Amersham Pharm Biotech Ab | A method for the removal/purification of serum albumins and means for use in the method |
| US20030005468A1 (en) * | 1998-06-19 | 2003-01-02 | Meade Harry M. | Methods and vectors for improving nucleic acid expression |
| DE69931645T2 (de) * | 1998-09-24 | 2007-05-16 | Pharming Intellectual Property Bv | Reinigung von fibrinogen aus flüssigkeiten mittels ausfällung und hydrophobischer-interaktion-chromatographie |
| EP1148779B1 (en) * | 1999-01-06 | 2007-12-12 | Merrimack Pharmaceuticals, Inc. | Expression of secreted human alpha-fetoprotein in transgenic animals |
| AU5553600A (en) | 1999-06-23 | 2001-01-31 | Ppl Therapeutics (Scotland) Ltd | Fusion proteins incorporating lysozyme |
| NZ522971A (en) * | 2000-05-05 | 2005-02-25 | Gtc Biotherapeutics Inc | Transgenically produced decorin in the mammary gland of a transgenic animal |
| US20030195707A1 (en) * | 2000-05-25 | 2003-10-16 | Schork Nicholas J | Methods of dna marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
| US20020077775A1 (en) * | 2000-05-25 | 2002-06-20 | Schork Nicholas J. | Methods of DNA marker-based genetic analysis using estimated haplotype frequencies and uses thereof |
| US20040226053A1 (en) * | 2000-10-13 | 2004-11-11 | Meade Harry M. | Methods of producing a target molecule in a transgenic animal and purification of the target molecule |
| CA2448432A1 (en) * | 2001-06-13 | 2002-12-19 | Taurus Hsa Llc | Purification of human serum albumin |
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| US20060253913A1 (en) * | 2001-12-21 | 2006-11-09 | Yue-Jin Huang | Production of hSA-linked butyrylcholinesterases in transgenic mammals |
| AU2003247354A1 (en) * | 2002-04-24 | 2003-11-10 | Intermediate ingredient for dairy product manufacturing and method of making the same | |
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| GB0216001D0 (en) * | 2002-07-10 | 2002-08-21 | Nat Blood Authority | Process and composition |
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| JP2006507839A (ja) * | 2002-11-27 | 2006-03-09 | ジーティーシー バイオセラピューティックス インコーポレイテッド | 乳中に安定して産生される改変抗体およびその製造方法 |
| US20040231010A1 (en) * | 2003-01-09 | 2004-11-18 | Murray James D. | Lysozyme transgenic ungulates |
| US20040210953A1 (en) * | 2003-01-09 | 2004-10-21 | Murray James D. | Lysozyme transgenic ungulates |
| PT1587923E (pt) | 2003-01-22 | 2011-12-07 | Univ Duke | Construções melhoradas para a expressão de polipéptidos lisossomais |
| CA2516836A1 (en) * | 2003-02-24 | 2004-09-10 | Gtc Biotherapeutics, Inc. | Methods of tangential flow filtration and an apparatus therefore |
| US7125963B2 (en) * | 2004-03-03 | 2006-10-24 | En N Tech Inc | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions |
| US20050197496A1 (en) * | 2004-03-04 | 2005-09-08 | Gtc Biotherapeutics, Inc. | Methods of protein fractionation using high performance tangential flow filtration |
| US20050245444A1 (en) * | 2004-04-30 | 2005-11-03 | Yann Echelard | Method of using recombinant human antithrombin for neurocognitive disorders |
| US20060121004A1 (en) * | 2004-12-07 | 2006-06-08 | Yann Echelard | Methods of reducing the incidence of rejection in tissue transplantation through the use of recombinant human antithrombin |
| US20060130159A1 (en) * | 2004-12-09 | 2006-06-15 | Nick Masiello | Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum |
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| WO2006138647A2 (en) * | 2005-06-16 | 2006-12-28 | Gtc Biotherapeutics, Inc. | Method of making recombinant human antibodies for use in biosensor technology |
| WO2007014244A2 (en) * | 2005-07-25 | 2007-02-01 | Gtc Biotherapeutics, Inc. | Method of purifying recombinant human antithrombin to enhance the viral and prion safety profile |
| KR20080068089A (ko) * | 2005-10-21 | 2008-07-22 | 지티씨바이오쎄라퓨틱스,인크. | 항체 의존성 세포 독성 활성이 증강된 항체, 그 생산 및사용 방법 |
| US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
| FR2901707B1 (fr) * | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
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| JP5208428B2 (ja) * | 2007-01-30 | 2013-06-12 | 雪印メグミルク株式会社 | 美肌剤 |
| FR2912310B1 (fr) | 2007-02-13 | 2009-08-07 | Kasan Sarl | Nouvelles compositions cosmetiques et/ou pharmaceutiques et leurs applications. |
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| EP3715356B1 (en) * | 2009-12-18 | 2023-10-11 | CSL Limited | Method of purifying polypeptides |
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| BR112015019348A2 (pt) | 2013-02-13 | 2017-08-22 | Lab Francais Du Fractionnement | Métodos para produção de proteína com glicosilação modificada e com sialilação aumentada, para aumentar a atividade de sialil transferase na glândula mamária e para produzir sialil transferase, proteína com glicosilação modificada ou proteína com sialilação aumentada, composição, sialil transferase, mamífero transgênico, e, célula epitelial mamária |
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| WO2015186004A2 (en) * | 2014-06-02 | 2015-12-10 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Production of fc fragments |
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| JP2021524464A (ja) * | 2018-05-24 | 2021-09-13 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司Ｊｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．， Ｌｔｄ． | 組換えヒトインスリンまたはそのアナログの前駆体の調製方法 |
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| FR2459619B1 (fr) | 1979-06-26 | 1983-07-29 | Agronomique Inst Nat Rech | Procede pour l'obtention a partir de lactoserum, d'un produit enrichi en alpha-lactalbumine et applications dudit procede |
| FR2487642B2 (fr) | 1980-07-31 | 1985-10-18 | Bel Fromageries | Procede de preparation de fractions proteiques par ultrafiltration et chromatographie d'exclusion et d'echange d'ions |
| DE3432718C1 (de) | 1984-09-06 | 1986-05-22 | Biotest Pharma GmbH, 6000 Frankfurt | Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen |
| FR2584727B1 (fr) | 1985-07-11 | 1988-06-17 | Roussel Uclaf | Procede d'extraction de proteines du lait, produits, application du procede, et compositions pharmaceutiques |
| JPS62298536A (ja) | 1986-06-17 | 1987-12-25 | Green Cross Corp:The | 生理活性物質の自動精製方法および自動精製装置 |
| DE3743440A1 (de) * | 1987-12-21 | 1989-06-29 | Gauri Kailash Kumar | Verfahren zum trennen der geloesten und ungeloesten bestandteile von milch |
| US4897465A (en) | 1988-10-12 | 1990-01-30 | Abbott Laboratories | Enrichment and concentration of proteins by ultrafiltration |
| CA2351200A1 (en) | 1989-12-01 | 1991-06-13 | Gene Pharming Europe Bv | Production of recombinant polypeptides by bovine species and transgenic methods |
| NL9001650A (nl) | 1990-07-19 | 1992-02-17 | Ver Coop Melkind | Werkwijze voor de bereiding van een melkeiwit-isolaat. |
| US5256294A (en) | 1990-09-17 | 1993-10-26 | Genentech, Inc. | Tangential flow filtration process and apparatus |
| US5175013A (en) | 1990-12-31 | 1992-12-29 | The Pillsbury Company | Frozen dessert compositions and products |
| US5178894A (en) | 1991-09-26 | 1993-01-12 | Silvia P. Rudel | High non-fat milk content bread products having improved keeping qualities |
| AU4537393A (en) | 1992-06-15 | 1994-01-04 | Gene Pharming Europe Bv | Production of recombinant polypeptides by bovine species and transgenic methods |
| US5256437A (en) * | 1992-06-19 | 1993-10-26 | Pall Corporation | Product and process of making sterile milk through dynamic microfiltration |
| DK0804070T3 (da) | 1993-03-09 | 2000-08-07 | Genzyme Corp | Fremgangsmåde til isolering af proteiner fra mælk |
| EP1142484A2 (en) | 1994-02-16 | 2001-10-10 | Pharming Intellectual Property BV | Isolation of lactoferrin from milk |
| US5597486A (en) * | 1995-05-01 | 1997-01-28 | Millipore Investment Holdings Limited | Membrane filtration with optimized addition of second liquid to maximize flux |
-
1996
- 1996-05-13 US US08/648,235 patent/US6268487B1/en not_active Expired - Lifetime
-
1997
- 1997-05-13 EP EP97923643A patent/EP0923308B1/en not_active Expired - Lifetime
- 1997-05-13 DE DE69715641T patent/DE69715641T2/de not_active Expired - Lifetime
- 1997-05-13 WO PCT/US1997/008044 patent/WO1997042835A1/en not_active Ceased
- 1997-05-13 AT AT97923643T patent/ATE224145T1/de active
- 1997-05-13 NZ NZ332916A patent/NZ332916A/xx not_active IP Right Cessation
- 1997-05-13 PT PT97923643T patent/PT923308E/pt unknown
- 1997-05-13 DK DK97923643T patent/DK0923308T3/da active
- 1997-05-13 ES ES97923643T patent/ES2182074T3/es not_active Expired - Lifetime
- 1997-05-13 DE DE122007000008C patent/DE122007000008I2/de active Active
- 1997-05-13 CA CA002254871A patent/CA2254871C/en not_active Expired - Lifetime
- 1997-05-13 JP JP54103697A patent/JP4476362B2/ja not_active Expired - Lifetime
- 1997-05-13 AU AU29402/97A patent/AU725993B2/en not_active Expired
-
2007
- 2007-01-12 LU LU91305C patent/LU91305I2/fr unknown
- 2007-01-19 NL NL300256C patent/NL300256I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000510701A (ja) | 2000-08-22 |
| DE122007000008I1 (de) | 2009-05-20 |
| DE69715641D1 (de) | 2002-10-24 |
| US6268487B1 (en) | 2001-07-31 |
| LU91305I2 (fr) | 2007-03-12 |
| NL300256I1 (nl) | 2007-04-02 |
| EP0923308B1 (en) | 2002-09-18 |
| DK0923308T3 (da) | 2002-10-14 |
| WO1997042835A1 (en) | 1997-11-20 |
| DE122007000008I2 (de) | 2011-01-13 |
| EP0923308A4 (cg-RX-API-DMAC7.html) | 1999-06-30 |
| AU2940297A (en) | 1997-12-05 |
| CA2254871A1 (en) | 1997-11-20 |
| PT923308E (pt) | 2002-11-29 |
| NZ332916A (en) | 2000-05-26 |
| AU725993B2 (en) | 2000-10-26 |
| DE69715641T2 (de) | 2003-08-07 |
| EP0923308A1 (en) | 1999-06-23 |
| ATE224145T1 (de) | 2002-10-15 |
| CA2254871C (en) | 2008-03-25 |
| ES2182074T3 (es) | 2003-03-01 |
| NL300256I2 (nl) | 2007-09-03 |
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