JP4465148B2 - Ｎｏｇｏレセプターホモログ - Google Patents

Ｎｏｇｏレセプターホモログ Download PDF

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Publication number
JP4465148B2
JP4465148B2 JP2002532629A JP2002532629A JP4465148B2 JP 4465148 B2 JP4465148 B2 JP 4465148B2 JP 2002532629 A JP2002532629 A JP 2002532629A JP 2002532629 A JP2002532629 A JP 2002532629A JP 4465148 B2 JP4465148 B2 JP 4465148B2
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JP
Japan
Prior art keywords
ngr
polypeptide
seq
protein
amino acids
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Expired - Fee Related
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JP2002532629A
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English (en)
Japanese (ja)
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JP2004528809A5 (cg-RX-API-DMAC7.html
JP2004528809A (ja
Inventor
スティーブン エム． ストリットマター，
リチャード エル． ケイト，
ディナー ダブリュー． ワイ． サー，
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Yale University
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Yale University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2002532629A 2000-10-06 2001-10-06 Ｎｏｇｏレセプターホモログ Expired - Fee Related JP4465148B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23836100P 2000-10-06 2000-10-06
PCT/US2001/031488 WO2002029059A2 (en) 2000-10-06 2001-10-06 Nogo receptor homologs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009022063A Division JP2009100767A (ja) 2000-10-06 2009-02-02 Ｎｏｇｏレセプターホモログ

Publications (3)

Publication Number Publication Date
JP2004528809A JP2004528809A (ja) 2004-09-24
JP2004528809A5 JP2004528809A5 (cg-RX-API-DMAC7.html) 2005-03-03
JP4465148B2 true JP4465148B2 (ja) 2010-05-19

Family

ID=22897532

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002532629A Expired - Fee Related JP4465148B2 (ja) 2000-10-06 2001-10-06 Ｎｏｇｏレセプターホモログ
JP2009022063A Withdrawn JP2009100767A (ja) 2000-10-06 2009-02-02 Ｎｏｇｏレセプターホモログ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009022063A Withdrawn JP2009100767A (ja) 2000-10-06 2009-02-02 Ｎｏｇｏレセプターホモログ

Country Status (12)

Country Link
US (5) US20030124704A1 (cg-RX-API-DMAC7.html)
EP (1) EP1325130B1 (cg-RX-API-DMAC7.html)
JP (2) JP4465148B2 (cg-RX-API-DMAC7.html)
AT (1) ATE458815T1 (cg-RX-API-DMAC7.html)
AU (2) AU1153902A (cg-RX-API-DMAC7.html)
CA (1) CA2424834A1 (cg-RX-API-DMAC7.html)
DE (1) DE60141409D1 (cg-RX-API-DMAC7.html)
DK (1) DK1325130T3 (cg-RX-API-DMAC7.html)
ES (1) ES2341608T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ525422A (cg-RX-API-DMAC7.html)
PT (1) PT1325130E (cg-RX-API-DMAC7.html)
WO (1) WO2002029059A2 (cg-RX-API-DMAC7.html)

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PT1325130E (pt) * 2000-10-06 2010-05-31 Biogen Idec Inc Homólogos do receptor de nogo
US20040259092A1 (en) * 2001-08-27 2004-12-23 Carmen Barske Nogo receptor homologues and their use
JP2005519584A (ja) * 2001-10-22 2005-07-07 ノバルティス アクチエンゲゼルシャフト Ｎｏｇｏレセプターホモログおよびそれらの使用
US7309485B2 (en) * 2001-12-03 2007-12-18 Children's Medical Center Corporation Reducing myelin-mediated inhibition of axon regeneration
WO2004005510A1 (ja) * 2002-07-05 2004-01-15 Shionogi & Co., Ltd. 新規Nogo受容体様ポリペプチドおよびそのＤＮＡ
WO2004014311A2 (en) * 2002-08-10 2004-02-19 Yale University Nogo receptor antagonists
ES2537015T3 (es) 2003-03-19 2015-06-01 Biogen Ma Inc. Proteína de unión del receptor de NOGO
WO2004090103A2 (en) 2003-04-04 2004-10-21 University Of Rochester Identification of novel nogo-receptors and methods related thereto
MXPA05011100A (es) * 2003-04-16 2006-04-18 Univ Yale Antagonistas de receptor nogo para el tratamiento de condiciones que comprenden placas amiloideas.
US20080274112A1 (en) * 2003-08-07 2008-11-06 Lee Daniel H S Nogo Receptor Antagonists
CA2549000A1 (en) * 2003-12-16 2005-06-30 Children's Medical Center Corporation Method for treating neurological disorders
US8912144B2 (en) * 2003-12-16 2014-12-16 Children's Medical Center Corporation Method for treating stroke via administration of NEP1-40 and inosine
CN1946418A (zh) * 2004-01-30 2007-04-11 比奥根艾迪克Ma公司 利用nogo受体拮抗剂治疗涉及多巴胺能神经元退变的疾病
PL1776136T3 (pl) 2004-06-24 2013-03-29 Biogen Ma Inc Leczenie stanów związanych z demielinizacją
JP2008515804A (ja) * 2004-10-01 2008-05-15 イェール ユニバーシティ Ｎｏｇｏ−Ａポリペプチド断片、改変体Ｎｏｇｏレセプター１ポリペプチドおよびそれらの使用
EP1904091A4 (en) * 2005-07-07 2009-12-23 Univ Yale COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH
ES2434470T3 (es) 2005-07-08 2013-12-16 Biogen Idec Ma Inc. Anticuerpos SP35 y usos de éstos
WO2007025219A2 (en) * 2005-08-25 2007-03-01 Biogen Idec Ma Inc. Nogo receptor polypeptides and polypeptide fragments and uses thereof
EP2526968A3 (en) 2006-01-27 2013-05-22 Biogen Idec MA Inc. Nogo receptor antagonists
US20110123535A1 (en) * 2006-05-15 2011-05-26 Biogen Idec Ma Inc. Use of Nogo Receptor-1 (NGR1) for Promoting Oligodendrocyte Survival
WO2007137303A2 (en) * 2006-05-24 2007-11-29 Myelin Repair Foundation, Inc. Permeability of blood-brain barrier
US20100047232A1 (en) * 2006-11-14 2010-02-25 Jasvinder Atwal Modulators of neuronal regeneration
CN101529255A (zh) * 2006-11-14 2009-09-09 健泰科生物技术公司 神经元再生的调控剂
WO2009009743A2 (en) * 2007-07-12 2009-01-15 Institute For Advance Study Sequence optimization for expression of a foreign gene
WO2009076359A2 (en) * 2007-12-11 2009-06-18 Genentech, Inc. Modulators of neuronal regeneration
US8992918B2 (en) 2008-03-13 2015-03-31 Yale University Reactivation of axon growth and recovery in chronic spinal cord injury
CL2009001155A1 (es) * 2008-05-13 2010-06-04 Genentech Inc Anticuerpo anti-pirb/lilrb aislado; polinucleotido que lo codifica; vector; celula huesped; metodo de obtencion; composicion farmaceutica que lo comprende; kit; y su uso para tratar enfermedades neurodegenerativas.
DK2982695T3 (da) 2008-07-09 2019-05-13 Biogen Ma Inc Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf
EP2392208B1 (en) * 2010-06-07 2016-05-04 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use
US9120111B2 (en) 2012-02-24 2015-09-01 Rain Bird Corporation Arc adjustable rotary sprinkler having full-circle operation and automatic matched precipitation
EA030716B1 (ru) 2012-05-14 2018-09-28 Байоджен Ма Инк. Антагонисты lingo-2 для лечения заболеваний, в которых участвуют двигательные нейроны
US9156043B2 (en) 2012-07-13 2015-10-13 Rain Bird Corporation Arc adjustable rotary sprinkler with automatic matched precipitation
US10435467B2 (en) 2015-01-08 2019-10-08 Biogen Ma Inc. LINGO-1 antagonists and uses for treatment of demyelinating disorders
US12343748B2 (en) 2021-03-16 2025-07-01 Rain Bird Corporation Multi-mode rotor sprinkler apparatus and method
US12434252B2 (en) 2022-04-20 2025-10-07 Rain Bird Corporation Full-circle and part-circle rotor sprinkler
US12440855B2 (en) 2022-10-27 2025-10-14 Rain Bird Corporation Multi-mode rotor sprinkler apparatus and method

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Also Published As

Publication number Publication date
US20070104713A1 (en) 2007-05-10
US20110129477A1 (en) 2011-06-02
WO2002029059A2 (en) 2002-04-11
JP2009100767A (ja) 2009-05-14
NZ525422A (en) 2006-09-29
PT1325130E (pt) 2010-05-31
DK1325130T3 (da) 2010-05-25
AU2002211539B2 (en) 2007-01-25
ATE458815T1 (de) 2010-03-15
US20050048520A1 (en) 2005-03-03
WO2002029059A9 (en) 2003-05-15
WO2002029059A3 (en) 2003-01-23
US7173118B2 (en) 2007-02-06
CA2424834A1 (en) 2002-04-11
DE60141409D1 (de) 2010-04-08
AU1153902A (en) 2002-04-15
US20090175850A1 (en) 2009-07-09
EP1325130B1 (en) 2010-02-24
JP2004528809A (ja) 2004-09-24
ES2341608T3 (es) 2010-06-23
US20030124704A1 (en) 2003-07-03
US7456255B2 (en) 2008-11-25
EP1325130A2 (en) 2003-07-09

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